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Tinea Corporis

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181. What is the best treatment for a persistent fungal skin infection of the foot microbiologically confirmed as Trichophyton rubrum?

on fungal (dermatophyte) skin infections (2), which offers treatment options for athlete’s foot, tinea cruris and tinea corporis, mostly caused by Trichophyton rubrum. Again the treatments discussed are not specific to persistent infection, however, the guideline offers alternative options if first-line treatment is unsuccessful. The information is to extensive to be reproduced here, but can be viewed in full by following the link in the references. Answered 24 July 2006 Follow us: © 2019 Trip Database

2006 TRIP Answers

182. A Proof of Concept Study With 0.5% Roflumilast Cream in Patients With Mild to Moderate Plaque Psoriasis

consistently and correctly such as implants, injectables, combined oral contraceptives, some IUDs, sexual abstinence or vasectomised partner Exclusion Criteria: Patient has spontaneously improving or rapidly deteriorating plaque psoriasis within at least the past 3 month. Patients who have a known history of psoriasis unresponsive to topical treatments. Patient has a physical condition (e.g., atopic dermatitis, contact dermatitis, tinea corporis) which, in the Investigator's opinion, might impair

2008 Clinical Trials

183. Quality of Life Study in Adults With Facial Eczema

response, or hypersensitivity to topical pimecrolimus cream 1%. Who have concurrent skin disease (e.g. acne) of such severity in the study area that it could interfere with the evaluation. Who have active bacterial (e.g. impetigo), viral (e.g. chicken pox, herpes simplex) or fungal infections (e.g. tinea corporis, intertriginosa) Who have received any investigational drugs within 8 weeks of visit 1, or plan to use any other investigational drugs during the course of this study Who, in the opinion

2005 Clinical Trials

184. Efficacy of triclosan soap against superficial dermatomycoses: a double-blind clinical trial in 224 primary school-children in Kilombero District, Morogoro Region, Tanzania. Full Text available with Trip Pro

was not statistically significant. Overall cure rates for Triclosan and placebo groups taken together were 21.8% for tinea versicolor, 58.3% for tinea capitis, 55.5% for tinea corporis and 68.8% for tinea pedis. This was confirmed microscopically. For the majority of the children the dermatomycoses improved significantly.The results strongly argue for regular soap use against common dermatomycoses as a low-cost and effective treatment. This promising finding should be considered in settings where dermatophyte

2007 International journal of dermatology Controlled trial quality: uncertain

185. Efficacy and Safety Study of Advantan for Maintenance Treatment of Atopic Dermatitis

History of moderate to severe form of atopic dermatitis for at least two years Exclusion Criteria: Pregnancy, breast feeding Known immune, hepatic, or renal insufficiency Acute herpes simplex or mollusca contagiosa infection Acute and severe impetigo contagiosa. A slight superinfection of eczema is no exclusion criterion Severe other viral, bacterial, or fungal skin infection (chicken pox, prominent tinea corporis) Acute infestations (e.g. head lice, scabies) Contacts and Locations Go to Information

2005 Clinical Trials

186. Microsporum canis in a neonatal intensive care unit patient. (Abstract)

Microsporum canis in a neonatal intensive care unit patient. A 45-day-old male neonate (born 25 weeks and 5 days) presented with an annular, erythematosquamous eruption covering the head, neck, trunk, upper limbs and thighs. The eruption most resembled tinea corporis, however unusual the setting. Routine fungal culture grew Microsporum canis. No contacts could be identified. No previous case of tinea corporis had been seen in this neonatal unit, and very few reports are in the literature

2008 Australasian Journal of Dermatology

187. Characteristics of superficial fungal infections in the Riyadh region of Saudi Arabia. (Abstract)

and 82 females), aged between 5 months and 67 years, were included in this study. The diagnosis of SFI was based on clinical presentation confirmed by laboratory analysis. The type of mycotic pathogen and the site of infection were recorded as a function of age and sex.Onychomycosis (40.3%) was the most frequent infection, followed by tinea capitis (21.9%), tinea pedis (16%), tinea cruris (15.1%), and tinea corporis (6.7%). Tinea capitis was most prevalent (15.1%) in children (male to female ratio, 1 (...) : 1.57), whereas tinea pedis was most common (11.8%) in adults (male to female ratio, 1 : 2.5). Trichophyton mentagrophytes and Microsporum canis were the most common dermatophytes responsible for tinea infections, and T. mentagrophytes, Candida spp., and Aspergillus spp. were mainly responsible for onychomycosis.The prevalence of SFI was twofold greater in females than males. Children were most commonly affected by tinea capitis, whereas adults generally suffered from tinea pedis. The frequency

2008 International Journal of Dermatology

188. A virulent genotype of Microsporum canis is responsible for the majority of human infections. Full Text available with Trip Pro

. Human cases mainly concern moderately inflammatory tinea corporis and tinea capitis, but, as cases of highly inflammatory ringworm are also observed, the question arises as to whether all lineages of M. canis are equally virulent to humans. In this study, two microsatellite markers were developed and used to analyse a global set of 101 M. canis strains to reveal patterns of genetic variation and dispersal. Using a Bayesian and a distance approach for structuring the M. canis samples, three

2007 Journal of Medical Microbiology

189. Dermatitis-like squamous cell carcinoma. (Abstract)

Dermatitis-like squamous cell carcinoma. A 78-year-old man with a 2-year history of a large dermatitis-like plaque of his thigh is described. It had a raised elevated border, resembling persistent fungal dermatitis (tinea corporis). However, it proved to be a squamous cell carcinoma, prompting this description and a reminder that skin cancer may mimic dermatitis.

2004 Dermatologic Surgery

190. A nationwide survey of Trichophyton tonsurans infection among combat sport club members in Japan using a questionnaire form and the hairbrush method. (Abstract)

. Demographic factors associated with high positive rates (> or =20%) of the infection were familial T. tonsurans infection (20.0%), history of tinea corporis (24.2%), increased dandruff (32.1%), and concomitant tinea corporis (31.6%). Those with positive hairbrush culture results without current or previous tinea were considered asymptomatic carriers.The study population was limited to members of judo clubs all over Japan; they were asked to participate in this survey via the All Japan Judo

2006 Journal of American Academy of Dermatology

191. First report on autochthonous urease-positive Trichophyton rubrum (T. raubitschekii) from South-east Europe. (Abstract)

First report on autochthonous urease-positive Trichophyton rubrum (T. raubitschekii) from South-east Europe. Trichophyton raubitschekii is a dermatophyte belonging to the T. rubrum complex and is differentiated principally by its positive urease activity and production of profuse macroconidia and microconidia in culture. It is classically isolated from African, South-east Asian and Australian aboriginal patients with tinea corporis or tinea cruris.This study was undertaken to screen Greek (...) amplifying repeat elements of the intergenic spacer region and by PCR fingerprinting.Five Greek and one Bulgarian T. raubitschekii strains were identified comprising isolates from patients with tinea manuum (one), tinea corporis (one), tinea cruris (one) and tinea unguium (three). Only one strain had the classical T. raubitschekii microscopic morphology, whereas the remaining five presented a dominant arthroconidial phenotype. Both typing methods clustered all T. raubitschekii and T. rubrum isolates

2005 British Journal of Dermatology

192. Dermatophytosis

. The most common organisms are: Trichophytons rubrum , Trichophytons tonsurans , Trichophytons interdigitale and Trichophytons mentagrophytes . Microsporum canis . Epidermophyton floccosum . Clinical classification is according to site: Scalp - tinea capitis. Feet - tinea pedis. Hands - tinea manuum. Nail - tinea unguium (or onychomycosis). Beard area - tinea barbae. Groin - tinea cruris. Body including trunk and arms - tinea corporis. Epidemiology Infection is very common all over the world. Some types (...) are more common than others, with tinea pedis being most common in adults and tinea capitis the most common in children. Onychomycosis is also extremely common. The Royal College of General Practitioner's Birmingham Research Unit reported an annual incidence of dermatomycosis of 16 per 10,000 persons (age standardised). [ ] A survey of 15,333 dermatophytes obtained from a UK reference laboratory from 1980 through 2005 found that the relative frequencies of isolations of M. canis (cat and dog ringworm

2008 Mentor

193. Discoid (Nummular) Eczema

below the knee. The lesions then flatten to macules, usually with brown hyperpigmentation from the inflammation. It gradually lightens but the pigment may never completely fade, particularly below the knee. Plaques may clear in the centre and resemble tinea corporis. The condition varies in intensity rather than being constant. The eruptions are intensely itchy but they may also burn or sting. Pruritus is always worst at night, almost irrespective of the aetiology. There tends to be seasonal (...) or thickened by chronic scratching, more violaceous and, often, has no clear border. Stasis dermatitis may occur simultaneously on the lower extremities and venous stasis may lead to the development of both conditions. are often found on the extensor surfaces, especially at the elbows and knees and the scalp is often involved. The scale is usually thick and silver. Investigations Scrapings of lesions should be analysed to exclude tinea. If there is secondary infection, swabs should be taken. Patch testing

2008 Mentor

194. Oil of bitter orange: new topical antifungal agent. (Abstract)

Oil of bitter orange: new topical antifungal agent. Superficial dermatophyte infection is one of the most common dermatologic diseases. Some of these infections are extremely resistant to therapy.Sixty patients participated in this study; they were classified into three groups (20 patients in each). All groups had comparable numbers of patients with tinea corporis, cruris, and pedis. Group 1 was treated with a 25% emulsion of oil of bitter orange (OBO) three times daily; group 2 was treated

1996 International journal of dermatology

195. Short-duration therapy with terbinafine 1% cream in dermatophyte skin infections. (Abstract)

Short-duration therapy with terbinafine 1% cream in dermatophyte skin infections. In a multicentre, double-blind, parallel-group study, the efficacy and safety of a single application of terbinafine 1% cream was compared with 3, 5 and 7 days' once-daily therapy in the treatment of tinea pedis and tinea corporis/cruris. Seventy-eight patients with tinea pedis (58 male, 20 female; mean age 36, range 19-80) and 21 patients with tinea corporis or tinea cruris (16 male, 5 female; mean age 37, range (...) 22-72), presenting in general practice, were entered into the study. Of these, 65 patients with tinea pedis and 14 with tinea corporis or cruris completed the study and were evaluable. Twenty-eight days after commencing therapy 78, 83, 82 and 83% of patients with tinea pedis in the 1-, 3-, 5-, and 7-day treatment groups, respectively, were mycologically cured, and 61, 78, 71 and 67%, respectively, were 'effectively treated'. There was no statistically significant difference between treatment

1994 The British journal of dermatology Controlled trial quality: uncertain

196. Itraconazole in the treatment of dermatophytoses: a comparison of two daily dosages. (Abstract)

Itraconazole in the treatment of dermatophytoses: a comparison of two daily dosages. Itraconazole, the first orally active triazole antifungal agent, was tested in 185 cases of acute or chronic (recurrent) dermatophytosis. The skin infections were divided into two major diagnostic groups: tinea corporis/tinea cruris (91 cases) and tinea pedis/tinea manuum (94 cases). Each patient was randomly assigned to a regimen of 50 or 100 mg of itraconazole daily. Of the cases of tinea corporis (...) and/or tinea cruris, 94% responded to 50 mg of itraconazole daily and 96% to 100 mg daily. The effects of therapy were evident earlier when 100 mg daily was given. Of the cases of tinea pedis and/or tinea manuum, 80% responded to 50 mg of itraconazole daily and 94% to 100 mg. Again, improvement was seen sooner with the 100-mg regimen. Only five patients (2.9%) reported minor adverse reactions. Hematologic and blood-biochemical parameters were monitored before treatment and at biweekly intervals thereafter

1987 Reviews of infectious diseases Controlled trial quality: uncertain

197. Tolciclate versus miconazole, a double-blind trial in patients with dermatomycosis. (Abstract)

Tolciclate versus miconazole, a double-blind trial in patients with dermatomycosis. Eighty-one patients with dermatomycosis such as tinea corporis, tinea cruris, tinea pedis and pityriasis versicolor were treated with tolciclate 1% cream or miconazole 2% cream. Parasitological cure was obtained in 100% of the patients given tolciclate and in 97.4% of those given miconazole. Patients and investigator considered tolciclate treatment as excellent, respectively, in 76.2% and 73.8% of the cases

1980 The Journal of international medical research Controlled trial quality: uncertain

198. A comparative double blind study of ketoconazole and griseofulvin in dermatophytosis. (Abstract)

given. Seventy-five per cent (total 80) and 74% (total 72) of all infected sites treated with ketoconazole and griseofulvin respectively were cleared of infection. However, in toe nail infections the respective cure rates were only 21% and 17%. Ketoconazole appeared to act more rapidly in curing tinea corporis or tinea cruris due to Trichophyton rubrum, whereas griseofulvin was superior in T. interdigitale infections. No serious side-effects were encountered in either treatment group. In view

1985 The British journal of dermatology

199. Cutaneous fungal and viral infections in athletes. (Abstract)

Cutaneous fungal and viral infections in athletes. Fungal and viral cutaneous infections are common among athletes and can develop quickly into widespread outbreaks. To prevent such outbreaks, the team physician must be familiar with common cutaneous infections including tinea corporis, tinea capitis, tinea pedis, herpes simplex, molluscum contagiosum, and human papillomaviruses. Appropriate treatment and management of these infections allows the athlete to safely return to play and safeguards

2007 Clinics in Sports Medicine

200. Characteristics of superficial mycoses in Malta. (Abstract)

by C. albicans (n = 12) and C. tropicalis (n = 6). Nondermatophyte filamentous fungi were isolated from nail specimens only.In this study, superficial fungal infections were reported more commonly in female (n = 207) than in male (n = 182) patients. M. canis was the chief agent of tinea capitis and tinea corporis, whilst T. rubrum was the main causative agent of tinea pedis, tinea manuum, and tinea unguium. Onychomycosis due to Candida species was more common in female than in male patients.

2003 International Journal of Dermatology

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