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Thyroid Function Summary

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141. Phase 2 Trial of Apatinib Mesylate in Locally Advanced/Metastatic Differentiated Thyroid Carcinoma

: Recruiting First Posted : May 30, 2017 Last Update Posted : May 30, 2017 See Sponsor: Tianjin Medical University Cancer Institute and Hospital Information provided by (Responsible Party): Tianjin Medical University Cancer Institute and Hospital Study Details Study Description Go to Brief Summary: This is a non-randomized, phase II, open label study of Apatinib Mesylate in patients with with locally advanced or metastatic differentiated thyroid carcinoma (DTC). The purpose of this study is to evaluate (...) Phase 2 Trial of Apatinib Mesylate in Locally Advanced/Metastatic Differentiated Thyroid Carcinoma Phase 2 Trial of Apatinib Mesylate in Locally Advanced/Metastatic Differentiated Thyroid Carcinoma - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove

2017 Clinical Trials

142. The Feasibility and Safety of the TOETVA for Benign Thyroid Nodules

: The University of Hong Kong Information provided by (Responsible Party): Dr. Lang Hung Hin, Brian, The University of Hong Kong Study Details Study Description Go to Brief Summary: Thyroid surgery has been developed as a new technique for zero scar in surgery by applying transoral endoscopic thyroidectomy with sublingual approach. The new technique is locating the surgery which pierced through floor of mouth, cause severe tissue damage, high complication, and conversion rates to open surgery and surgical (...) after surgery The hematoma rate after TOETVA [ Time Frame: 12 months ] To record the situation of hematoma after surgery The vocal cord palsy rate after TOETVA [ Time Frame: 12 months ] To calculate the vocal cord situation after surgery within 12 months The hypoparathyroidism rate after TOETVA [ Time Frame: 12 months ] To record the thyroid function from blood test in 12 months after surgery and calculate the rate of hypo-parathyroid function The pain score of patient after TOETVA [ Time Frame: 12

2017 Clinical Trials

143. Atezolizumab Combinations With Chemotherapy for Anaplastic and Poorly Differentiated Thyroid Carcinomas

Recruitment Status : Recruiting First Posted : June 8, 2017 Last Update Posted : March 5, 2019 See Sponsor: M.D. Anderson Cancer Center Collaborator: Genentech, Inc. Information provided by (Responsible Party): M.D. Anderson Cancer Center Study Details Study Description Go to Brief Summary: Objectives: Primary To determine if targeted therapy + atezolizumab (cohorts 1-3) will lead to improved overall survival (OS) in patients with anaplastic thyroid carcinoma (ATC). Secondary To evaluate the safety (...) Atezolizumab Combinations With Chemotherapy for Anaplastic and Poorly Differentiated Thyroid Carcinomas Atezolizumab Combinations With Chemotherapy for Anaplastic and Poorly Differentiated Thyroid Carcinomas - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100

2017 Clinical Trials

144. Pembrolizumab, Chemotherapy, and Radiation Therapy With or Without Surgery in Treating Patients With Anaplastic Thyroid Cancer

: Active, not recruiting First Posted : July 7, 2017 Last Update Posted : May 1, 2018 Sponsor: Mayo Clinic Collaborator: National Cancer Institute (NCI) Information provided by (Responsible Party): Mayo Clinic Study Details Study Description Go to Brief Summary: This phase II trial studies how well pembrolizumab, chemotherapy, and radiation therapy work with or without surgery in treating patients with anaplastic thyroid cancer. Monoclonal antibodies, such as pembrolizumab, may interfere (...) Pembrolizumab, Chemotherapy, and Radiation Therapy With or Without Surgery in Treating Patients With Anaplastic Thyroid Cancer Pembrolizumab, Chemotherapy, and Radiation Therapy With or Without Surgery in Treating Patients With Anaplastic Thyroid Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached

2017 Clinical Trials

145. Cyclophosphamide and Sirolimus for the Treatment of Metastatic, RAI-refractory, Differentiated Thyroid Cancer

: NCT03099356 Recruitment Status : Recruiting First Posted : April 4, 2017 Last Update Posted : June 6, 2018 See Sponsor: University of Michigan Rogel Cancer Center Information provided by (Responsible Party): University of Michigan Rogel Cancer Center Study Details Study Description Go to Brief Summary: This study will be a non-randomized pilot trial using Cyclophosphamide and Sirolimus for the treatment of metastatic differentiated thyroid cancer. Patients will be treated with Sirolimus 4 mg, PO, days 1 (...) Cyclophosphamide and Sirolimus for the Treatment of Metastatic, RAI-refractory, Differentiated Thyroid Cancer Cyclophosphamide and Sirolimus for the Treatment of Metastatic, RAI-refractory, Differentiated Thyroid Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies

2017 Clinical Trials

146. Immunotherapy and Stereotactic Body Radiotherapy (SBRT) for Metastatic Anaplastic Thyroid Cancer

Immunotherapy and Stereotactic Body Radiotherapy (SBRT) for Metastatic Anaplastic Thyroid Cancer Immunotherapy and Stereotactic Body Radiotherapy (SBRT) for Metastatic Anaplastic Thyroid Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one (...) or more studies before adding more. Immunotherapy and Stereotactic Body Radiotherapy (SBRT) for Metastatic Anaplastic Thyroid Cancer The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03122496 Recruitment Status : Recruiting

2017 Clinical Trials

147. Study of PET Imaging With 18F-TFB in Patients With Thyroid Cancer

Sloan Kettering Cancer Center Information provided by (Responsible Party): Memorial Sloan Kettering Cancer Center Study Details Study Description Go to Brief Summary: The goal of the study is to evaluate a new imaging test that may allows the investigators to predict the uptake of radioactive iodine by thyroid cancer faster than the current standard and that does not interfere with the uptake of radioactive iodine used for therapy. Condition or disease Intervention/treatment Phase Thyroid Cancer (...) Study of PET Imaging With 18F-TFB in Patients With Thyroid Cancer Study of PET Imaging With 18F-TFB in Patients With Thyroid Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Study of PET Imaging

2017 Clinical Trials

148. A Clinical Study of Apatinib in Patients With Local Progressive/Metastatic Refractory Thyroid Cancer

Status : Recruiting First Posted : June 27, 2017 Last Update Posted : July 2, 2017 See Sponsor: Chinese Academy of Medical Sciences Information provided by (Responsible Party): Shengyu Zhou, Chinese Academy of Medical Sciences Study Details Study Description Go to Brief Summary: This is a single-center, open-label, single arm,exploratory clinical trial evaluating the efficacy and safety of Apatinib in patients with local progressive/metastatic refractory thyroid cancer. Condition or disease (...) A Clinical Study of Apatinib in Patients With Local Progressive/Metastatic Refractory Thyroid Cancer A Clinical Study of Apatinib in Patients With Local Progressive/Metastatic Refractory Thyroid Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please

2017 Clinical Trials

149. Evaluation of the Pattern of Thyroid Dysfunctions in Patients With Metabolic Syndrome

, 2017 Last Update Posted : July 3, 2018 See Sponsor: Assiut University Information provided by (Responsible Party): GAAbdelhay, Assiut University Study Details Study Description Go to Brief Summary: The study on evaluation the pattern of TD in MetS population may help us to know the magnitude of overlap of these two disease entities and may highlight the importance of thyroid function tests in patients with MetS. This can lead to proper planning and adequate management strategies, resulting (...) , lipids and protein metabolism. These hormones accelerate metabolic processes and may be associated with metabolic syndrome. Hyperthyroidism is usually associated with low cholesterol and glucose intolerance; whereas hypothyroidism is associated with high cholesterol tendency, and patients are prone to weight gain and cardiac signs like bradycardia. Thyroid functions affect the components of MetS including HDLcholesterol (HDL-C), triglycerides (TG), blood pressure and plasma glucose. Thyroid

2017 Clinical Trials

150. RAI Plus Immunotherapy for Recurrent/Metastatic Thyroid Cancers

Kettering Cancer Center Collaborators: AstraZeneca MedImmune LLC Information provided by (Responsible Party): Memorial Sloan Kettering Cancer Center Study Details Study Description Go to Brief Summary: The purpose of this study is to find out what effects, good and/or bad, a drug called durvalumab combined with Thyrogen-stimulated RAI, has on the patient and thyroid cancer. Durvalumab is a drug that has been developed to activate the immune system by blocking a protein called programmed death ligand-1 (...) RAI Plus Immunotherapy for Recurrent/Metastatic Thyroid Cancers RAI Plus Immunotherapy for Recurrent/Metastatic Thyroid Cancers - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. RAI Plus Immunotherapy

2017 Clinical Trials

151. Long Period Observation of Biochemical Survey and Ultrasonography in Thyroid Diseases and Subclinical Thyroid Diseases

, not recruiting First Posted : August 16, 2016 Last Update Posted : March 30, 2018 Sponsor: National Taiwan University Hospital Information provided by (Responsible Party): National Taiwan University Hospital Study Details Study Description Go to Brief Summary: Clinical and subclinical thyroid disease is usually used to describe patients with mild symptoms correlated to hyperthyroid or hypothyroid state. Therapeutic decision for clinical and subclinical thyroid dysfunction should be considered individually (...) . But long term outcome for treatment of such functional and structural thyroid diseases had not been recorded delicately in Taiwan. Further investigations should be observed in the future.The purpose of this study is aiming for early prevention and detection the potential risk factors for thyroid diseases in Taiwan. Condition or disease Thyroid Diseases Detailed Description: Clinical and subclinical thyroid disease is usually used to describe patients with mild symptoms correlated to hyperthyroid

2016 Clinical Trials

152. Management of Thyroid Cancer

with thyroid cancer 61 15 Thyroid cancer in childhood 64 16 Pathology reporting, grading and staging of thyroid cancers 16.1 General principles 65 16.2 Pathology report 65 16.3 Pathological staging 65 16.4 Staging protocol 65 16.5 Summary of thyroid cancer types 65 17 Medullary thyroid cancer 17.1 Presentation 69 17.2 Initial investigations of patients with suspected or con? rmed MTC 70 17.3 Treatment 70 17.4 Adjuvant therapies 71 17.5 Pathology 72 17.6 Follow-up for MTC 73 17.7 Investigation of persistent (...) 21.3 Screening 86 21.4 Diagnosis and referral 86 21.5 Summary of treatment of thyroid cancer 87 21.6 Follow-up 88 Appendices 1. Assay methodology 89 2. Recognition of MEN3 (MEN2B) 94 3. Search methodology 95 4. Patient information 97 Patient support groups 97 Websites with useful information for patients 97 Lea? ets for patients 1. The thyroid gland and thyroid cancer – tests and treatment 99 2. Information for patients being investigated for thyroid lumps 102 3. Surgery for thyroid Cancer 104 4

2014 British Association of Endocrine and Thyroid Surgeons

153. Thyroid Cancer Treatment (PDQ®): Patient Version

Thyroid Cancer Treatment (PDQ®): Patient Version Thyroid Cancer Treatment (Adult) (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf Warning: The NCBI web site requires JavaScript to function. Search database Search term Search NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health. PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002-. PDQ Cancer Information Summaries [Internet]. Bethesda (MD): ; 2002 (...) -. Search term Thyroid Cancer Treatment (Adult) (PDQ®) Patient Version PDQ Adult Treatment Editorial Board . Published online: May 16, 2019. This PDQ cancer information summary has current information about the treatment of adult thyroid cancer. It is meant to inform and help patients, families, and caregivers. It does not give formal guidelines or recommendations for making decisions about health care. Editorial Boards write the PDQ cancer information summaries and keep them up to date. These Boards

2016 PDQ - NCI's Comprehensive Cancer Database

154. Thyroid Cancer Treatment (PDQ®): Health Professional Version

Thyroid Cancer Treatment (PDQ®): Health Professional Version Thyroid Cancer Treatment (Adult) (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf Warning: The NCBI web site requires JavaScript to function. Search database Search term Search NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health. PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002-. PDQ Cancer Information Summaries [Internet]. Bethesda (MD (...) ): ; 2002-. Search term Thyroid Cancer Treatment (Adult) (PDQ®) Health Professional Version PDQ Adult Treatment Editorial Board . Published online: January 30, 2020. This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the treatment of adult thyroid cancer. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care

2015 PDQ - NCI's Comprehensive Cancer Database

155. The association of maternal thyroid function and autoimmunity with preterm birth: an IPD meta-analysis

The association of maternal thyroid function and autoimmunity with preterm birth: an IPD meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web (...) to be extracted: other as well as a to meta-analysis of pre-clinical studies are available. Example: A meta‐analysis will be performed for all outcome measures reported in 10 or more articles. For subgroup analysis a minimum of 8 studies per subgroup is required. If meta‐analysis is not possible, data will be reported through a descriptive summary. ">Planned approach Example: number of metastases: standardized mean difference; incidence of metastasis: risk ratio. ">Effect measure The random-effects model

2016 PROSPERO

156. Thyroid function within normal range and risk of atrial fibrillation: a systematic review and individual participant data analysis

Thyroid function within normal range and risk of atrial fibrillation: a systematic review and individual participant data analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne (...) of publication, language, journal. ">Data to be extracted: other as well as a to meta-analysis of pre-clinical studies are available. Example: A meta‐analysis will be performed for all outcome measures reported in 10 or more articles. For subgroup analysis a minimum of 8 studies per subgroup is required. If meta‐analysis is not possible, data will be reported through a descriptive summary. ">Planned approach Example: number of metastases: standardized mean difference; incidence of metastasis: risk ratio

2016 PROSPERO

157. The relationship between thyroid function in the reference range and risk of fractures: an individual participant data analysis

The relationship between thyroid function in the reference range and risk of fractures: an individual participant data analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne (...) of publication, language, journal. ">Data to be extracted: other as well as a to meta-analysis of pre-clinical studies are available. Example: A meta‐analysis will be performed for all outcome measures reported in 10 or more articles. For subgroup analysis a minimum of 8 studies per subgroup is required. If meta‐analysis is not possible, data will be reported through a descriptive summary. ">Planned approach Example: number of metastases: standardized mean difference; incidence of metastasis: risk ratio

2016 PROSPERO

158. Effect of Perioperative Intravenous Lidocaine Infusion and Magnesium Infusion on the Functional Recovery After General Anesthesia in the Patients Undergoing Thyroid Surgery

Effect of Perioperative Intravenous Lidocaine Infusion and Magnesium Infusion on the Functional Recovery After General Anesthesia in the Patients Undergoing Thyroid Surgery Effect of Perioperative Intravenous Lidocaine Infusion and Magnesium Infusion on the Functional Recovery After General Anesthesia in the Patients Undergoing Thyroid Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information (...) . Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Effect of Perioperative Intravenous Lidocaine Infusion and Magnesium Infusion on the Functional Recovery After General Anesthesia in the Patients Undergoing Thyroid Surgery The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does

2013 Clinical Trials

159. Which Thyroid Antibody Assays Should be Checked in Patients with Thyroid Disease?

Stimulating Immunoglobulins in Graves’ and anti-Thyroglobulin, anti-thyroid peroxidase, and anti-thyroid symporter in all autoimmune thyroid disorders, as well as TSH-blocking antibodies. The TSH-blocking antibodies interfere with the ability of native TSH and TSI to up-regulate the TSH receptor. The net thyroid functional effect is the sum of the trophic and inhibitory factors, anti-enzyme effects, and destructive T-Cell phenomenoa . For example, in Graves’ disease activation of the thyroid stimulating (...) myxedema, or primarily affect several organ systems, like Graves’ disease. The manifestations of ITD are influenced by co-morbidities, past events, environmental factors, and notably local T-lymphocyte phenomena and several immunoglobulins that have unique specificities and impact on thyroid function. TSI binds to and stimulates the TSH receptor to enhance thyroid hormone levels, anti-TPO antibody interferes with the function of the thyroid peroxidase enzyme to reduce thyroxine production, TSH-blocking

2010 Clinical Correlations

160. Preconceptional Thyroid Screening and Childhood Nerocognitive Function

Preconceptional Thyroid Screening and Childhood Nerocognitive Function Preconceptional Thyroid Screening and Childhood Nerocognitive Function - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Preconceptional (...) Thyroid Screening and Childhood Nerocognitive Function The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01744743 Recruitment Status : Unknown Verified December 2012 by Xiaotian Li, Fudan University. Recruitment status was: Recruiting First Posted : December 7, 2012 Last Update Posted : December 11, 2012

2012 Clinical Trials

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