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Thyroid Function Summary

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101. Maternal Thyroid Function in Early Pregnancy and Their Relationship With Gestational Diabetes Mellitus

Maternal Thyroid Function in Early Pregnancy and Their Relationship With Gestational Diabetes Mellitus Maternal Thyroid Function in Early Pregnancy and Their Relationship With Gestational Diabetes Mellitus - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please (...) remove one or more studies before adding more. Maternal Thyroid Function in Early Pregnancy and Their Relationship With Gestational Diabetes Mellitus The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02555332 Recruitment Status : Completed First Posted : September 21, 2015 Last Update Posted : September

2015 Clinical Trials

102. Iodine supplementation in pregnancy in areas of mild-to-moderate iodine deficiency: a systematic review of the effects on maternal and infant thyroid function, and child cognition

Iodine supplementation in pregnancy in areas of mild-to-moderate iodine deficiency: a systematic review of the effects on maternal and infant thyroid function, and child cognition Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email (...) : secondary outcome(s) Example: 1st author, year of publication, language, journal. ">Data to be extracted: other as well as a to meta-analysis of pre-clinical studies are available. Example: A meta‐analysis will be performed for all outcome measures reported in 10 or more articles. For subgroup analysis a minimum of 8 studies per subgroup is required. If meta‐analysis is not possible, data will be reported through a descriptive summary. ">Planned approach Example: number of metastases: standardized mean

2018 PROSPERO

103. Efficacy of Apatinib in Radioactive Iodine-refractory Differentiated Thyroid Cancer

Update Posted : March 20, 2019 See Sponsor: Peking Union Medical College Hospital Information provided by (Responsible Party): Yansong Lin, Peking Union Medical College Hospital Study Details Study Description Go to Brief Summary: Radioactive iodine-refractory differentiated thyroid cancer (RAIR-DTC) is a great challenge in the treatment of thyroid cancer. Tyrosine kinase inhibitors (TKIs), like sorafenib and lenvatinib which have been approved by food and drug administration (FDA), could (...) Efficacy of Apatinib in Radioactive Iodine-refractory Differentiated Thyroid Cancer Efficacy of Apatinib in Radioactive Iodine-refractory Differentiated Thyroid Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before

2017 Clinical Trials

104. Thyroid in Bariatric Surgery

Description Go to Brief Summary: This study is expected to provide novel data regarding potential structural and functional changes of the thyroid gland in morbidly obese adults following significant weight loss through bariatric surgery. These data will complement evidence from epidemiological studies regarding the association of obesity and alterations in thyroid function. Potentially this study may justify further longer-term studies regarding the effects of weight gain and/or weight loss (...) on the morphology of the thyroid gland and could help to form recommendations regarding follow-up investigations for the thyroid in morbidly obese patients. Condition or disease Intervention/treatment Phase Thyroid Obesity Insulin Resistance Autoimmune Thyroiditis Procedure: Bariatric surgery Not Applicable Detailed Description: Alterations in thyroid function are reported in obesity. Thyroid hormones and thyroid-stimulating hormone (TSH) concentrations have been variously described as normal, elevated, or low

2017 Clinical Trials

105. The Role of Thyroid Status in Regulating Brown Adipose Tissue Activity, White Adipose Tissue Partitioning and Resting Energy Expenditure

health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03064542 Recruitment Status : Recruiting First Posted : February 27, 2017 Last Update Posted : August 23, 2017 See Sponsor: Clinical Nutrition Research Centre, Singapore Collaborator: Agency for Science, Technology and Research Information provided by (Responsible Party): Melvin Leow, Tan Tock Seng Hospital Study Details Study Description Go to Brief Summary: To determine how thyroid status regulates (...) clinic at TTSH, the doctors will review that result and decide if a repeat test is needed. If subjects are confirmed by blood tests to have Graves' disease type of hyperthyroidism, they are eligible to take part in this study. However, approximately 2 teaspoons (~ 10 mL) of blood will be taken for baseline thyroid function test just prior to the initiation of anti-thyroid drugs. Pre-menopausal women will also undergo a urine pregnancy test to exclude pregnancy prior to participation at study entry

2017 Clinical Trials

106. Pembrolizumab in Recurrent or Metastatic Medullary Thyroid Cancer

(NCI) Information provided by (Responsible Party): National Institutes of Health Clinical Center (CC) ( National Cancer Institute (NCI) ) Study Details Study Description Go to Brief Summary: Background: Medullary thyroid cancer (MTC) is a tumor of the thyroid gland. Surgery is the only current treatment to cure it. The drug pembrolizumab (MK-3475) is a new type of cancer therapy. It works by allowing the immune system to detect and kill tumor cells. Objective: To test how pembrolizumab affects (...) Pembrolizumab in Recurrent or Metastatic Medullary Thyroid Cancer Pembrolizumab in Recurrent or Metastatic Medullary Thyroid Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Pembrolizumab in Recurrent

2017 Clinical Trials

107. Pembrolizumab With Chemotherapy for Poorly Chemo-responsive Thyroid and Salivary Gland Tumors

: Recruiting First Posted : December 4, 2017 Last Update Posted : April 11, 2018 See Sponsor: University of Chicago Information provided by (Responsible Party): University of Chicago Study Details Study Description Go to Brief Summary: Phase II, 2-cohort, single arm trial treated with the combination of the following two agents: Pembrolizumab (MK3475) 200mg, every three weeks, iv Docetaxel 75mg/m2, every three weeks, iv Condition or disease Intervention/treatment Phase Thyroid Cancer Salivary Gland Cancer (...) Pembrolizumab With Chemotherapy for Poorly Chemo-responsive Thyroid and Salivary Gland Tumors Pembrolizumab With Chemotherapy for Poorly Chemo-responsive Thyroid and Salivary Gland Tumors - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one

2017 Clinical Trials

108. Myeloid Cell Reprogramming in Thyroid Carcinoma

): Radboud University Study Details Study Description Go to Brief Summary: This study investigates the reprogramming of myeloid cells in patients with thyroid carcinoma. The investigators hypothesize that tumor-derived factors change the function of myeloid cells in such a way that these immune cells promote tumor growth rather than combat the tumor. Condition or disease Thyroid Cancer Study Design Go to Layout table for study information Study Type : Observational Estimated Enrollment : 50 participants (...) Myeloid Cell Reprogramming in Thyroid Carcinoma Myeloid Cell Reprogramming in Thyroid Carcinoma - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Myeloid Cell Reprogramming in Thyroid Carcinoma The safety

2017 Clinical Trials

109. Health-related quality-of-life assessment in surgical patients with papillary thyroid carcinoma: A single-center analysis from Mainland China. (PubMed)

showed significantly lower scores than those of the control group in 7 domains of the HRQoL: role-physical (RP), bodily pain (BP), general health (GH), vitality (VT), social functioning (SF), role-emotional (RE), and mental health (MH). PTC was a risk factor for a low Physical Component Summary (PCS) score and a low Mental Component Summary (MCS) score (all P values were less than .05). Significant reductions in the scores of all 8 domains were observed at 1 month after the operation, and obvious (...) Health-related quality-of-life assessment in surgical patients with papillary thyroid carcinoma: A single-center analysis from Mainland China. Even with a favorable prognosis, the health-related quality of life (HRQoL) of papillary thyroid carcinoma (PTC) patients remains unclear and conflicting. Thus, in the present study, we compared the HRQoL of PTC patients with that of the general population (GP).The study was performed in our thyroid and parathyroid surgery department, and 186 PTC

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2017 Medicine

110. EEG Alterations in Preterm Infants With Thyroid Dysfunction

and hereby, parental informed consent was already obtained. TH function is assessed in preterm infants ≤ 34 weeks as part of the clinical care protocol. No additional blood samples were taken. Quantitative EEG measures will be compared between the preterm infants with THOP (circulating thyroxine levels< P10) and without THOP. Logisitic regression will be performed to determine the effect of thyroid function as well as other clinical and demographic variables, on functional brain development at term (...) Ages Eligible for Study: 24 Weeks to 27 Weeks (Child) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Sampling Method: Probability Sample Study Population Preterm infants who had EEG recordings in the framework of the Resilience study and gestational age < 28 weeks. Criteria Inclusion Criteria: gestational age < 28 weeks serial EEG recordings available thyroid function test on the first day of life and at the end of the first week of life available Exclusion Criteria: Presence

2017 Clinical Trials

111. Deciding on Active Surveillance or Surgery for Primary Management of Low Risk Papillary Thyroid Cancer

Estimated Study Completion Date : December 31, 2026 Resource links provided by the National Library of Medicine related topics: available for: resources: Groups and Cohorts Go to Group/Cohort Active surveillance Patients under active surveillance choose to not have immediate thyroidectomy. Patients are closely monitored with respect to clinical status, ultrasound imaging, biochemical indices (thyroid function, thyroglobulin, and thyroglobulin antibodies) and any thyroid cancer-related treatments (...) Deciding on Active Surveillance or Surgery for Primary Management of Low Risk Papillary Thyroid Cancer Deciding on Active Surveillance or Surgery for Primary Management of Low Risk Papillary Thyroid Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please

2017 Clinical Trials

112. Thyroid Dysfunction and Dyslipidemia in Patients With Chronic Kidney Diseases

Posted : September 11, 2017 See Sponsor: Assiut University Information provided by (Responsible Party): Sara Elewa Ahmed, Assiut University Study Details Study Description Go to Brief Summary: Early diagnosis of thyroid and lipid disorders by regular screening, and treatment of such disorders in CKD patients may be highly beneficial to slow progression of CKD. The study will be conducted to investigate thyroid function and lipid profile in patients with chronic kidney disease. Condition or disease (...) with a number of serious complications, including increased incidence of cardiovascular disease, hyperlipidemia, anemia and metabolic bone disease .CKD patients should be assessed for the presence of these complications and receive optimal treatment to reduce their morbidity and mortality . CKD affects thyroid function in many ways, including low thyroid circulating hormone levels, altered peripheral hormone metabolism, insufficient binding to carrier proteins, reduced tissue thyroid hormone content

2017 Clinical Trials

113. A Clinical Study of Apatinib in Patients With Local Progressive/Metastatic Refractory Thyroid Cancer

Status : Recruiting First Posted : June 27, 2017 Last Update Posted : July 2, 2017 See Sponsor: Chinese Academy of Medical Sciences Information provided by (Responsible Party): Shengyu Zhou, Chinese Academy of Medical Sciences Study Details Study Description Go to Brief Summary: This is a single-center, open-label, single arm,exploratory clinical trial evaluating the efficacy and safety of Apatinib in patients with local progressive/metastatic refractory thyroid cancer. Condition or disease (...) A Clinical Study of Apatinib in Patients With Local Progressive/Metastatic Refractory Thyroid Cancer A Clinical Study of Apatinib in Patients With Local Progressive/Metastatic Refractory Thyroid Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please

2017 Clinical Trials

114. Pembrolizumab, Chemotherapy, and Radiation Therapy With or Without Surgery in Treating Patients With Anaplastic Thyroid Cancer

: Active, not recruiting First Posted : July 7, 2017 Last Update Posted : May 1, 2018 Sponsor: Mayo Clinic Collaborator: National Cancer Institute (NCI) Information provided by (Responsible Party): Mayo Clinic Study Details Study Description Go to Brief Summary: This phase II trial studies how well pembrolizumab, chemotherapy, and radiation therapy work with or without surgery in treating patients with anaplastic thyroid cancer. Monoclonal antibodies, such as pembrolizumab, may interfere (...) Pembrolizumab, Chemotherapy, and Radiation Therapy With or Without Surgery in Treating Patients With Anaplastic Thyroid Cancer Pembrolizumab, Chemotherapy, and Radiation Therapy With or Without Surgery in Treating Patients With Anaplastic Thyroid Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached

2017 Clinical Trials

115. Study of PET Imaging With 18F-TFB in Patients With Thyroid Cancer

Sloan Kettering Cancer Center Information provided by (Responsible Party): Memorial Sloan Kettering Cancer Center Study Details Study Description Go to Brief Summary: The goal of the study is to evaluate a new imaging test that may allows the investigators to predict the uptake of radioactive iodine by thyroid cancer faster than the current standard and that does not interfere with the uptake of radioactive iodine used for therapy. Condition or disease Intervention/treatment Phase Thyroid Cancer (...) Study of PET Imaging With 18F-TFB in Patients With Thyroid Cancer Study of PET Imaging With 18F-TFB in Patients With Thyroid Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Study of PET Imaging

2017 Clinical Trials

116. Nivolumab Plus Ipilimumab in Thyroid Cancer

provided by (Responsible Party): Jochen Lorch, MD, Dana-Farber Cancer Institute Study Details Study Description Go to Brief Summary: This research study is studying nivolumab, an investigational drug, in combination with ipilimumab, also an investigational drug, as a possible treatment for thyroid cancer. The drugs involved in this study are: Nivolumab (Opdivo™) Ipilimumab (Yervoy™) Condition or disease Intervention/treatment Phase Thyroid Cancer Drug: Nivolumab Drug: Ipilimumab Phase 2 Detailed (...) kinase inhibitor (TKI) failure and progression within 13 months prior to enrollment (10 patients) and anaplastic thyroid cancer (7 patients) Any number of lines of prior treatment are allowed Any line of prior treatment for patients under 65y, over 65y must have at least one prior line of TKI treatment Age 18 years or older ECOG performance status ≤2 (Karnofsky ≥60%, see Appendix A) Participants must have normal organ and marrow function as defined below: Screening laboratory values must meet

2017 Clinical Trials

117. The Efficacy of Intermediate Cervical Plexus Block Versus Cutaneous and Thyroid Capsular Blocks

First Posted : September 1, 2017 Last Update Posted : October 11, 2017 See Sponsor: Mansoura University Information provided by (Responsible Party): Mansoura University Study Details Study Description Go to Brief Summary: Thyroid gland surgery is one of the most commonly performed operations for either benign or malignant pathologies Pain related to thyroid surgery is of moderate intensity .which may be treated with NSAIDs or opioids. However, Opioids have many well-known undesirable effects (...) table for eligibility information Ages Eligible for Study: 20 Years to 60 Years (Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: American Society of Anesthesiologists physical status grade I and grade II. Euthyroidism after thyroid function tests Exclusion Criteria: Patient refusal. Thyroid gland more than 5 cm size. Retrosternal extension. Planned block neck dissection. Neuromuscular diseases Hematological diseases. Bleeding diseases. Coagulation

2017 Clinical Trials

118. PLD Combined With Cisplatin in the Treatment of Advanced Poorly Differentiated Thyroid Carcinoma

First Posted : January 2, 2018 Last Update Posted : January 3, 2018 See Sponsor: CSPC ZhongQi Pharmaceutical Technology Co., Ltd. Information provided by (Responsible Party): CSPC ZhongQi Pharmaceutical Technology Co., Ltd. Study Details Study Description Go to Brief Summary: This is a prospective, multicenter, open label Phase II Clinical Trial. 30 advanced poorly differentiated thyroid carcinoma patients who were histopathologically confirmed inoperable were enrolled in this study. Condition (...) in the treatment. [ Time Frame: A summary of adverse events of each cycle,from date of administration of drugs until 30 days after the last chemotherapy or progression,whichever came first,assessed up to 18 months. ] Evaluate the adverse reaction rate of drugs assessed by number and severity of adverse events in the treatment of advanced thyroid poorly differentiated carcinoma. quality of life assessment [ Time Frame: It will be assessed before the administration of drugs at each first day of the chemotherapy

2017 Clinical Trials

119. Potential Preventive Effect of Selenium on Iodine-induced Thyroid Autoimmunity During Pregnancy

without particular iodine supplementation. Participants are asked to complete a questionnaire on dietary habits concerning iodine. Thyroid function (thyroid-stimulating hormone, free thyroxine) and thyroperoxidase antibodies (TPO-Ab) and urinary iodine are measured during first, second and third trimester of pregnancy and week 8 after delivery in both, intervention and control group. Condition or disease Intervention/treatment Phase Pregnancy Thyroid Autoimmune Disease Iodine Deficiency Selenium (...) Potential Preventive Effect of Selenium on Iodine-induced Thyroid Autoimmunity During Pregnancy Potential Preventive Effect of Selenium on Iodine-induced Thyroid Autoimmunity During Pregnancy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one

2017 Clinical Trials

120. Gut Microbiota is Associated With Autoimmune Thyroid Disease

of Harbin Medical University Information provided by (Responsible Party): First Affiliated Hospital of Harbin Medical University Study Details Study Description Go to Brief Summary: Autoimmune thyroid disease (AITD), which includes Hashimoto's thyroiditis (HT) and Grave's disease (GD), are the most common organ-specific autoimmune diseases and affect more women than men, with a female-to-male ratio from 5 to 10. Many studies have indicated that alterations in the gut microbiota are important (...) with Methimazole Pill according to the guidelines Other Name: Methimazole Outcome Measures Go to Primary Outcome Measures : 16S rRNAgene sequencing was used to measure the diversity of gut microbiota [ Time Frame: HC, treatment_naive HT and treatment_naive GD patients samples were collected at the enroll. Treated GD patients were collected until thyroid function resumed to the normal for at least 3 months of methimazole withdrawal ] Intestinal microbes are different in different groups Secondary Outcome

2017 Clinical Trials

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