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Thyroid Function Summary

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21. Painless lymphocytic thyroiditis

Painless lymphocytic thyroiditis Painless lymphocytic thyroiditis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Painless lymphocytic thyroiditis Last reviewed: February 2019 Last updated: May 2018 Summary Autoimmune-mediated inflammation of the thyroid gland with release of thyroid hormone resulting in transient hyperthyroidism, frequently followed by a hypothyroid phase before recovery of normal thyroid function (...) -mediated lymphocytic inflammation of the thyroid gland resulting in a destructive thyroiditis with release of thyroid hormone and transient thyrotoxicosis (hyperthyroidism). Woolf PD. Transient painless thyroiditis with hyperthyroidism: a variant of lymphocytic thyroiditis? Endocr Rev. 1980 Fall;1(4):411-20. http://www.ncbi.nlm.nih.gov/pubmed/7018893?tool=bestpractice.com Samuels MH. Subacute, silent and postpartum thyroiditis. Med Clin North Am. 2012 Mar;96(2):223-33. http://www.ncbi.nlm.nih.gov

2018 BMJ Best Practice

22. Thyroid (Full text)

Treatment (PDQ®): Health Professional Version Thyroid Cancer Treatment (PDQ®) - National Library of Medicine - PubMed Health Warning: The NCBI web site requires JavaScript to function. | | | | | Search term Search database > > Thyroid Cancer Treatment (PDQ®): Health... PubMed Health. A service of the National Library of Medicine, National Institutes of Health. PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002-. PDQ Cancer Information (...) Summaries (...) , Sosa J A Record Status This is a critical abstract of an economic evaluation (...) that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary This study assessed the cost-effectiveness of calcitonin screening in combination with current screening practices, in the authors' setting, for the evaluation of thyroid

2018 Trip Latest and Greatest PubMed abstract

23. Recommendation on screening adults for asymptomatic thyroid dysfunction in primary care

of cardiac conditions (e.g., atrial fibrillation, heart failure) or bone fractures, and could lead to thyroid storm, an uncommon, life-threatening condition associated with tachycardia, extreme fatigue, fever and nausea. , Minor variations in thyroid function as measured by abnormal levels of TSH are often self-limiting. Observational studies have reported that levels of TSH appear to revert to normal without treatment in 37%–62% of patients with initially elevated levels and 51% with initially low (...) or thyroid surgery; exposure to medications known to affect thyroid function; exposure to thyroid radioiodine therapy, or radiotherapy to the head or neck area; or pituitary or hypothalamic diseases. Methods The task force is an independent panel of clinicians and methodologists that makes recommendations on primary and secondary prevention in primary care ( ). This recommendation was developed by a working group of 4 task force members (R.B., J.D., D.R. and B.T.) with scientific support from Public

2019 Canadian Task Force on Preventive Health Care

24. Research on Association Between Selenium Deficiencies and Change of Thyroid Function

Research on Association Between Selenium Deficiencies and Change of Thyroid Function Research on Association Between Selenium Deficiencies and Change of Thyroid Function - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Research on Association Between Selenium Deficiencies and Change of Thyroid Function The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03448588 Recruitment Status : Recruiting First Posted : February 28, 2018

2018 Clinical Trials

25. Gestational Age Specific Thyroid Function Reference Range

Kong Study Details Study Description Go to Brief Summary: It has been well accepted that maternal thyroid dysfunction has adverse affects on both mothers and fetuses. However, the dramatical changes during pregnancy make the interpretation of thyroid function test (TFT, i.e. free triiodothyronine [FT3], free thyroxine [FT4] and thyrotropin [TSH]) very difficult. Previous studies have shown that the level of thyroid hormones differs from non-pregnant population and varies from gestational ages (...) Gestational Age Specific Thyroid Function Reference Range Gestational Age Specific Thyroid Function Reference Range - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Gestational Age Specific Thyroid Function

2018 Clinical Trials

26. Genetic variations in TAS2R3 and TAS2R4 bitterness receptors modify papillary carcinoma risk and thyroid function in Korean females (Full text)

Genetic variations in TAS2R3 and TAS2R4 bitterness receptors modify papillary carcinoma risk and thyroid function in Korean females Type 2 taste receptors (T2Rs, TAS2Rs) mediate bitterness perception and are involved in diverse defence mechanisms in extraoral tissues. The thyrocyte-expressed T2Rs control thyroid hormone production, and this regulatory role may be associated with susceptibility to thyroid diseases. This study examined whether the variations in TAS2Rs modify the risk of papillary (...) thyroid carcinoma (PTC) and whether such T2R-related PTC risk is associated with genetically modified thyroid function. We conducted a case-control study with 763 Korean females, including 250 PTC cases. Seventy-three single-nucleotide polymorphisms in 13 TAS2R genes and the pre-diagnosis levels of 4 thyroid-related functional markers [total triiodothyronine (TT3), free thyroxine, thyroid-stimulating hormone and thyroglobulin] were analysed. Individuals with TAS2R3/4 CC haplotype (rs2270009

2018 Scientific reports PubMed abstract

27. Liver, Pancreas and Thyroid Function in Burn Patients

Information provided by (Responsible Party): The University of Texas Medical Branch, Galveston Study Details Study Description Go to Brief Summary: The purpose of this study is to determine the extent to which severe burn injuries affect the morphology and function of liver, pancreas and thyroid. The evaluation of the liver will be performed non-invasively with liver fibrosis scores based on standard blood parameters and the measurement of liver stiffness (correlated with liver fibrosis) and controlled (...) Liver, Pancreas and Thyroid Function in Burn Patients Liver, Pancreas and Thyroid Function in Burn Patients - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Liver, Pancreas and Thyroid Function in Burn

2018 Clinical Trials

28. PheWAS of a Polygenic Predictor of Thyroid Function

PheWAS of a Polygenic Predictor of Thyroid Function PheWAS of a Polygenic Predictor of Thyroid Function - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. PheWAS of a Polygenic Predictor of Thyroid Function (...) ): Joe Elie Salem, Groupe Hospitalier Pitie-Salpetriere Study Details Study Description Go to Brief Summary: Performing a phenome-wide association study (PheWAS) identifying clinical diagnoses associated with a polygenic predictor of Thyroid stimulating hormone (TSH) levels identified by a previously published genome-wide association study (GWAS). PheWAS will be applied in an electronic-health-record (EHR) cohort including North American (n: 37,154) and European participants using 1,318 phenotypes

2018 Clinical Trials

29. Correction of Selenium Deficiency Has Effect on Thyroid Function

Correction of Selenium Deficiency Has Effect on Thyroid Function Correction of Selenium Deficiency Has Effect on Thyroid Function - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Correction of Selenium (...) Deficiency Has Effect on Thyroid Function The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03445078 Recruitment Status : Not yet recruiting First Posted : February 26, 2018 Last Update Posted : May 31, 2018 See Sponsor: Peking

2018 Clinical Trials

30. The meta-analysis of the association between thyroid function and insulin resistance.

The meta-analysis of the association between thyroid function and insulin resistance. Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites (...) . ">Data to be extracted: secondary outcome(s) Example: 1st author, year of publication, language, journal. ">Data to be extracted: other as well as a to meta-analysis of pre-clinical studies are available. Example: A meta‐analysis will be performed for all outcome measures reported in 10 or more articles. For subgroup analysis a minimum of 8 studies per subgroup is required. If meta‐analysis is not possible, data will be reported through a descriptive summary. ">Planned approach If a meta-analysis

2020 PROSPERO

31. Association between thyroid function and total and cardiovascular mortality: A systematic review and meta-analysis

Association between thyroid function and total and cardiovascular mortality: A systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated (...) by Jablonski scale; continuous; Jablonski score. ">Data to be extracted: secondary outcome(s) Example: 1st author, year of publication, language, journal. ">Data to be extracted: other as well as a to meta-analysis of pre-clinical studies are available. Example: A meta‐analysis will be performed for all outcome measures reported in 10 or more articles. For subgroup analysis a minimum of 8 studies per subgroup is required. If meta‐analysis is not possible, data will be reported through a descriptive summary

2020 PROSPERO

32. Effect of levothyroxine on among women with normal thyroid function and thyroid autoimmunity: systematic review and meta-analysis of a randomized clinical trials

Effect of levothyroxine on among women with normal thyroid function and thyroid autoimmunity: systematic review and meta-analysis of a randomized clinical trials Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr (...) outcome(s) Example: 1st author, year of publication, language, journal. ">Data to be extracted: other as well as a to meta-analysis of pre-clinical studies are available. Example: A meta‐analysis will be performed for all outcome measures reported in 10 or more articles. For subgroup analysis a minimum of 8 studies per subgroup is required. If meta‐analysis is not possible, data will be reported through a descriptive summary. ">Planned approach Example: number of metastases: standardized mean

2018 PROSPERO

33. Thyroid Disease

There are a wide variety of diseases that affect the thyroid gland and range from hyperplastic to neoplastic, autoimmune, or inflammatory. They can present with functional abnormality or a palpable structural change. Imaging has a key role in diagnosing and characterizing the thyroid finding for management. Imaging is also essential in the management of thyroid cancer. Thyroid nodules are the most common finding in the thyroid gland. The majority of thyroid nodules are benign [1,2]. Initiating workup is costly (...) Measurement for Benign and Malignant Thyroid Disease [14]. Discussion of Procedures by Variant Variant 1: Palpable thyroid nodule. Not goiter. Euthyroid. Initial imaging. Screening for thyroid cancer by palpation is not recommended by the U.S. Preventive Task Force [15]. However, if a patient presents with a palpable neck nodule, the goal of imaging is to determine if the palpable abnormality corresponds to a thyroid nodule and to characterize the nodule for malignancy risk. Thyroid function tests should

2019 American College of Radiology

34. Clinical Practice Guidelines – Thyroid cancer

or declining in patient with no imaging evidence of disease Nonspeci?c imaging ?ndings or Tg 0.2–5ng/ml or TgAb levels stable or declining in the absence of structural or functional disease Nonspeci?c imaging ?ndings a Modi?ed from the 2015 ATA ongoing risk strati?cation (response to therapy) system [8]. ATA, American Thyroid Association; DTC, differentiated thyroid cancer; RAI, radioactive iodine; RRA, radioactive iodine remnant ablation; stimTg, TSH-stimu- lated serum thyroglobulin; Tg, thyroglobulin (...) with preservation of function. CND, central neck dissection; CT, computed tomography; DTC, differentiated thyroid cancer; EBRT, external beam radiotherapy; ETE, extrathyroidal extension; LND, lateral neck dissection; MRI, magnetic resonance imaging; N0, no evidence of locoregional lymph node metastasis; N1, regional lymph node metastasis; R0, no residual tumour; R1, microscopic residual tumour; TT, total thyroidectomy; US, ultrasound. Special article Annals of Oncology 1862 | Filetti et al. Volume 30 | Issue 12

2020 European Society for Medical Oncology

35. Toxic thyroid adenoma

Toxic thyroid adenoma Toxic thyroid adenoma - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Toxic thyroid adenoma Last reviewed: February 2019 Last updated: February 2019 Summary Typically a single large thyroid nodule accompanied by clinical and biochemical hyperthyroidism. Diagnosis confirmed by thyroid scan demonstrating a hot area and suppression of extranodular thyroid tissue. Hyperthyroidism caused by toxic (...) adenomas generally does not remit. Definitive treatment, such as radioactive iodine therapy, is usually required. Complications of untreated toxic adenomas may include sequelae of hyperthyroidism such as cardiac dysfunction or bone loss, or tracheal compression by large nodules. Definition A toxic adenoma is an autonomously functioning thyroid nodule that causes hyperthyroidism. Ross DS, Burch HB, Cooper DS, et al. 2016 American Thyroid Association guidelines for diagnosis and management

2017 BMJ Best Practice

36. Thyroid Cancer

Thyroid Cancer Thyroid cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up † S. Filetti 1 , C. Durante 1 , D. Hartl 2 , S. Leboulleux 3 , L.D. Locati 4 , K. Newbold 5 , M.G. Papotti 6 , A. Berruti 7 , on behalf of the ESMO Guidelines Committee* 1 Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Rome, Italy; 2 Department of Head and Neck Oncology, Gustave Roussy and Université Paris Saclay, Villejuif; 3 Department of Nuclear (...) : clinicalguidelines@esmo.org † Approved by the ESMO Guidelines Committee: February 2008, last update September 2019. This publication supersedes the previously published version—Ann Oncol 2012; 23 (Suppl. 7): vii110–vii119. Running header: ESMO Clinical Practice Guidelines thyroid cancer Word count: 11 701 (excluding key message, references, tables & figures) Key words: papillary thyroid cancer, follicular thyroid cancer, anaplastic thyroid cancer, medullary thyroid cancer, management Key message (online only): ©

2019 European Society for Medical Oncology

37. Iodine excess exposure during pregnancy and lactation impairs maternal thyroid function in rats (Full text)

Iodine excess exposure during pregnancy and lactation impairs maternal thyroid function in rats Adequate maternal iodine consumption during pregnancy and lactation guarantees normal thyroid hormones (TH) production, which is crucial to the development of the fetus. Indeed, iodine deficiency is clearly related to maternal hypothyroidism and deleterious effects in the fetal development. Conversely, the effects of iodine excess (IE) consumption on maternal thyroid function are still controversial (...) , increased thyroid oxidative stress and decreased expression of thyroid genes/proteins involved in TH synthesis, secretion and metabolism. Furthermore, Dio1 mRNA expression and D1 activity were reduced in the liver and the kidney of IE-treated animals. Finally, the mRNA expression of Slc5a5 and Slc26a4 were reduced in the mammary gland of IE-exposed rats. The latter results are in accordance with the reduction of prolactin expression and serum levels in IE-treated dams. In summary, our study indicates

2017 Endocrine connections PubMed abstract

38. Effects of different dl-selenomethionine and sodium selenite levels on growth performance, immune functions and serum thyroid hormones concentrations in broilers. (Abstract)

Effects of different dl-selenomethionine and sodium selenite levels on growth performance, immune functions and serum thyroid hormones concentrations in broilers. This trial was conducted in a 2 × 3 + 1 factorial arrangement based on a completely randomized design to evaluate the effects of different dl-selenomethionine (dl-Se-Met) and sodium selenite (SS) levels on growth performance, immune functions and serum thyroid hormones concentrations in broilers. A total of 840 Ross 308 broilers (7 (...) were significantly higher (p < 0.05) than those of broilers fed 0.05 or 0.25 mg Se/kg. In summary, we concluded that dl-Se-Met is more effective than SS in increasing immunity and promoting conversion of T4 to T3 , thus providing an effective way to improve the growth performance of broilers. Besides, based on a consideration of all experiment indices, 0.15 mg Se/kg was suggested to be the optimal level of Se supplementation under the conditions of this study. Journal of Animal Physiology

2017 Journal of animal physiology and animal nutrition Controlled trial quality: uncertain

39. Thyroid function and the risk of fibrosis of the liver, heart and lung in humans: a systematic review and meta-analysis

Thyroid function and the risk of fibrosis of the liver, heart and lung in humans: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any (...) . ">Data to be extracted: secondary outcome(s) Example: 1st author, year of publication, language, journal. ">Data to be extracted: other as well as a to meta-analysis of pre-clinical studies are available. Example: A meta‐analysis will be performed for all outcome measures reported in 10 or more articles. For subgroup analysis a minimum of 8 studies per subgroup is required. If meta‐analysis is not possible, data will be reported through a descriptive summary. ">Planned approach If a meta-analysis

2019 PROSPERO

40. Circulating irisin level in patients with abnormal thyroid function: a systematic review and meta-analysis

Circulating irisin level in patients with abnormal thyroid function: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files (...) . ">Data to be extracted: secondary outcome(s) Example: 1st author, year of publication, language, journal. ">Data to be extracted: other as well as a to meta-analysis of pre-clinical studies are available. Example: A meta‐analysis will be performed for all outcome measures reported in 10 or more articles. For subgroup analysis a minimum of 8 studies per subgroup is required. If meta‐analysis is not possible, data will be reported through a descriptive summary. ">Planned approach If a meta-analysis

2019 PROSPERO

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