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Thromboembolic Disease in Pregnancy

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161. Riociguat Versus Balloon Pulmonary Angioplasty in Non-operable Chronic thromboEmbolic Pulmonary Hypertension

Riociguat Versus Balloon Pulmonary Angioplasty in Non-operable Chronic thromboEmbolic Pulmonary Hypertension Riociguat Versus Balloon Pulmonary Angioplasty in Non-operable Chronic thromboEmbolic Pulmonary Hypertension - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (...) (100). Please remove one or more studies before adding more. Riociguat Versus Balloon Pulmonary Angioplasty in Non-operable Chronic thromboEmbolic Pulmonary Hypertension (RACE) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier

2015 Clinical Trials

162. Evaluation of Venous Thromboembolism Prevention in High-Risk Trauma Patients

enoxaparin dosing strategies. Condition or disease Intervention/treatment Phase Traumatic Injury Venous Thromboembolism Drug: Enoxaparin 40 mg q12h Drug: Enoxaparin 30 mg q8h Phase 4 Detailed Description: This is a pilot study to determine if AT-III serum concentrations differ between patients with normal (>= 0.1 IU/mL) versus subtherapeutic (<0.1 IU/mL) anti-Xa trough concentrations when placed on enoxaparin 30 mg twice daily for venous thromboembolism (VTE) prophylaxis. Secondarily, this study (...) table for MeSH terms Thromboembolism Venous Thromboembolism Wounds and Injuries Embolism and Thrombosis Vascular Diseases Cardiovascular Diseases Heparin, Low-Molecular-Weight Dalteparin Anticoagulants Fibrinolytic Agents Fibrin Modulating Agents Molecular Mechanisms of Pharmacological Action

2015 Clinical Trials

163. Epidemiology of venous thromboembolism. Full Text available with Trip Pro

Epidemiology of venous thromboembolism. Thrombosis can affect any venous circulation. Venous thromboembolism (VTE) includes deep-vein thrombosis of the leg or pelvis, and its complication, pulmonary embolism. VTE is a fairly common disease, particularly in older age, and is associated with reduced survival, substantial health-care costs, and a high rate of recurrence. VTE is a complex (multifactorial) disease, involving interactions between acquired or inherited predispositions to thrombosis (...) and various risk factors. Major risk factors for incident VTE include hospitalization for surgery or acute illness, active cancer, neurological disease with leg paresis, nursing-home confinement, trauma or fracture, superficial vein thrombosis, and-in women-pregnancy and puerperium, oral contraception, and hormone therapy. Although independent risk factors for incident VTE and predictors of VTE recurrence have been identified, and effective primary and secondary prophylaxis is available, the occurrence

2015 Nature reviews. Cardiology

164. Recurrent Miscarriage, Antiphospholipid Antibodies and the Risk of Thromboembolic Disease. (Abstract)

Recurrent Miscarriage, Antiphospholipid Antibodies and the Risk of Thromboembolic Disease. Miscarriage affects 15 % of women, and while most are sporadic, there is a subset comprising 2-5 % of couples that suffers recurrent miscarriage (RM). Much work has been carried out to try to identify the RM underlying mechanisms. A subgroup of women with RM has been demonstrated to be in a prothrombotic state before pregnancy. The long-term health implications of this hypercoagulability may imply (...) an increased risk of thrombotic events, including ischemic heart disease. Moreover, the presence of antiphospholipid antibodies (aPL), rather than thrombophilic genetic defects (i.e., factor V Leiden or prothrombin G202010A mutation) in patients with RM, is a determinant of thrombotic events later in life, especially among those patients having also classic cardiovascular risk factors. These facts may have therapeutic implications. The efficacy of long-term thromboprophylaxis and its associated risk

2012 Clinical Reviews in Allergy & Immunology

165. Pulmonary Embolism in Pregnancy

Pulmonary Embolism in Pregnancy Pulmonary Embolism in Pregnancy Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Pulmonary Embolism (...) in Pregnancy Pulmonary Embolism in Pregnancy Aka: Pulmonary Embolism in Pregnancy II. Epidemiology See Two thirds of thromboembolic events in pregnancy are DVT (diagnosable by ) Overall risk of Pulmonary Embolism in Pregnancy: 3 in 10,000 Risk of increases with advancing pregnancy and especially postpartum First trimester : 1 in 50,000 Third trimester : 1 in 10,000 Two thirds of pregnancy-related occur postpartum (esp after ) III. Symptoms and signs See may be present Unilateral leg signs of may be present

2018 FP Notebook

166. Immediate delivery versus expectant monitoring for hypertensive disorders of pregnancy between 34 and 37 weeks of gestation (HYPITAT-II): an open-label, randomised controlled trial. (Abstract)

and 44 non-academic hospitals in the Netherlands. Women with non-severe hypertensive disorders of pregnancy between 34 and 37 weeks of gestation were randomly allocated to either induction of labour or caesarean section within 24 h (immediate delivery) or a strategy aimed at prolonging pregnancy until 37 weeks of gestation (expectant monitoring). The primary outcomes were a composite of adverse maternal outcomes (thromboembolic disease, pulmonary oedema, eclampsia, HELLP syndrome, placental abruption (...) Immediate delivery versus expectant monitoring for hypertensive disorders of pregnancy between 34 and 37 weeks of gestation (HYPITAT-II): an open-label, randomised controlled trial. There is little evidence to guide the management of women with hypertensive disorders in late preterm pregnancy. We investigated the effect of immediate delivery versus expectant monitoring on maternal and neonatal outcomes in such women.We did an open-label, randomised controlled trial, in seven academic hospitals

2015 Lancet Controlled trial quality: predicted high

167. Chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease Chronic obstructive pulmonary disease - NICE CKS Share Chronic obstructive pulmonary disease - Summary Chronic obstructive pulmonary disease (COPD) is a treatable (but not curable) and largely preventable lung disease. COPD is characterized by airflow obstruction which is usually progressive, and not fully reversible. Tobacco smoking is the major risk factor for the development of COPD. Complications include disability and reduced quality of life (...) be discussed when appropriate and advance care planning offered. Have I got the right topic? Have I got the right topic? From age 35 years onwards. This CKS topic covers the diagnosis, management, and referral of people with chronic obstructive pulmonary disease (COPD). There are separate CKS topics on , , , , , , , , and . The target audience for this CKS topic is healthcare professionals working within the NHS in the UK, and providing first contact or primary healthcare. How up-to-date is this topic? How

2019 NICE Clinical Knowledge Summaries

168. Crohn's disease

, bronchitis, hyperhomocysteinemia, pancreatitis, renal stones, and venous thromboembolism. See the CKS topics on , , , and for more information. [ ; ; ; ; ; ; ] Prognosis What is the prognosis? Crohn's disease is a lifelong condition, typified by periods of relapse and remission with recurrent cycles of inflammation [ ] . A review of population-based studies of the natural history of Crohn's disease in adults found [ ]: The location of the disease (ileitis, colitis, or ileo-colitis) tended to remain (...) the management of suspected Crohn's disease in primary care. : covers the management of confirmed Crohn's disease in primary care. : covers advice on fertility and advice on the management of Crohn's disease during pregnancy and breastfeeding. Scenario: Suspected Crohn's disease Scenario: Suspected Crohn's disease From age 6 months onwards. Management Management of suspected Crohn's disease If Crohn's disease is : Arrange emergency hospital admission if the person is systemically unwell with symptoms

2019 NICE Clinical Knowledge Summaries

169. Pulmonary hypertensive vascular changes in lungs of patients with sudden unexpected death. Emphasis on congenital heart disease, Eisenmenger syndrome, postoperative deaths and death during pregnancy and postpartum. Full Text available with Trip Pro

Pulmonary hypertensive vascular changes in lungs of patients with sudden unexpected death. Emphasis on congenital heart disease, Eisenmenger syndrome, postoperative deaths and death during pregnancy and postpartum. Pulmonary hypertension (PH) in asymptomatic patients is a rare cause of sudden death. This study aims to determine the incidence of this entity and raise awareness among pathologists.We retrospectively investigated 44 cases of sudden unexpected death in relation to PH in patients (...) heart disease. The cause of PH was recognised as congenital heart disease in 27 patients (61.36%), 14 of whom had simple congenital heart disease, such as atrial or ventricular septal defect,and 13 had complex congenital heart disease with associated atrial septal defect or ventricular septal defect. The remaining 17 patients (29.55%) suffered from primary PH due to plexiform arteriopathy, veno-occlusive disease and thromboembolic disease. Extensive sampling of the lungs is required to detect

2014 Journal of Clinical Pathology

170. Maternal Collapse in Pregnancy and the Puerperium

, Placenta Praevia Accreta and Vasa Praevia: Diagnosis and Management. 67 4.6.2 Venous thromboembolism The specific management of massive pulmonary embolism is covered in the RCOG Green-top Guideline No. 28: Thromboembolic Disease in Pregnancy and the Puerperium: Acute Management. 68 4.6.3 Amniotic fluid embolism The management of AFE is supportive rather than specific, as there is no proven effective therapy. 2 12 of 24 RCOG Green-top Guideline No. 56 © Royal College of Obstetricians and Gynaecologists (...) The incidence of primary cardiac arrest in pregnancy is much rarer at around 1/30 000 maternities, and most cardiac events have preceding signs and symptoms. Aortic root dissection can present in otherwise healthy women, and signs and symptoms such as central chest or interscapular pain, a wide pulse pressure, mainly secondary to systolic hypertension, and a new cardiac murmur must prompt referral to a cardiologist and appropriate imaging. The incidence of congenital and rheumatic heart disease in pregnancy

2011 Royal College of Obstetricians and Gynaecologists

171. Oral contraceptives and thromboembolic disease. Full Text available with Trip Pro

Oral contraceptives and thromboembolic disease. 5648983 1968 07 04 2008 11 20 0007-1447 2 5601 1968 May 11 British medical journal Br Med J Oral contraceptives and thromboembolic disease. 366-7 Crawford J S JS eng Journal Article England Br Med J 0372673 0007-1447 0 Contraceptives, Oral AIM IM Contraceptives, Oral adverse effects Female Humans Pregnancy Thromboembolism chemically induced 1968 5 11 1968 5 11 0 1 1968 5 11 0 0 ppublish 5648983 PMC1985616

1968 British medical journal

172. Oral contraception and thromboembolic disease. Full Text available with Trip Pro

Oral contraception and thromboembolic disease. 5676080 1968 11 01 2008 11 20 0008-4409 99 3 1968 Jul 20 Canadian Medical Association journal Can Med Assoc J Oral contraception and thromboembolic disease. 131 Whyte J C JC eng Journal Article Canada Can Med Assoc J 0414110 0008-4409 0 Contraceptives, Oral AIM IM Contraceptives, Oral adverse effects Female Humans Pregnancy Pregnancy Complications, Cardiovascular mortality Thromboembolism chemically induced mortality 1968 7 20 1968 7 20 0 1 1968 7

1968 Canadian Medical Association Journal

173. Risk of thromboembolic disease in women taking oral contraceptives. A preliminary communication to the Medical Research Council by a Subcommittee. Full Text available with Trip Pro

Contraceptives, Oral adverse effects Coronary Disease chemically induced Female Humans Intracranial Embolism and Thrombosis chemically induced Middle Aged Phlebitis chemically induced Pregnancy Pulmonary Embolism chemically induced Retrospective Studies Thromboembolism chemically induced Thrombophlebitis chemically induced 1967 5 6 1967 5 6 0 1 1967 5 6 0 0 ppublish 6023133 PMC1841690 Br Med J. 1967 Mar 25;1(5542):726-9 6020089 Br Med J. 1965 Nov 13;2(5471):1164-6 5833621 (...) Risk of thromboembolic disease in women taking oral contraceptives. A preliminary communication to the Medical Research Council by a Subcommittee. 6023133 1967 06 23 2018 11 13 0007-1447 2 5548 1967 May 06 British medical journal Br Med J Risk of thromboembolic disease in women taking oral contraceptives. A preliminary communication to the Medical Research Council by a Subcommittee. 355-9 eng Journal Article England Br Med J 0372673 0007-1447 0 Contraceptives, Oral AIM IM Adolescent Adult

1967 British medical journal

174. Oral contraceptives and thromboembolic disease. Full Text available with Trip Pro

Oral contraceptives and thromboembolic disease. 6023128 1967 06 23 2018 11 13 0007-1447 2 5548 1967 May 06 British medical journal Br Med J Oral contraceptives and thromboembolic disease. 327-8 eng Journal Article England Br Med J 0372673 0007-1447 0 Contraceptives, Oral AIM IM Adult Contraceptives, Oral adverse effects Female Humans Pregnancy Thromboembolism chemically induced 1967 5 6 1967 5 6 0 1 1967 5 6 0 0 ppublish 6023128 PMC1841739 Br Med J. 1966 May 28;1(5499):1327-8 5934376

1967 British medical journal

175. Oral contraception and thromboembolic disease. Full Text available with Trip Pro

Oral contraception and thromboembolic disease. 5652942 1968 07 29 2018 11 13 0008-4409 98 23 1968 Jun 08 Canadian Medical Association journal Can Med Assoc J Oral contraception and thromboembolic disease. 1117-8 eng Journal Article Canada Can Med Assoc J 0414110 0008-4409 0 Contraceptives, Oral AIM IM Adult Contraceptives, Oral adverse effects Female Humans Pregnancy Pulmonary Embolism etiology mortality Thromboembolism etiology mortality 1968 6 8 1968 6 8 0 1 1968 6 8 0 0 ppublish 5652942

1968 Canadian Medical Association Journal

176. Acute and recurrent thromboembolic disease: a new concept of etiology. Full Text available with Trip Pro

Acute and recurrent thromboembolic disease: a new concept of etiology. 5344031 1969 12 02 2018 11 13 0003-4932 170 4 1969 Oct Annals of surgery Ann. Surg. Acute and recurrent thromboembolic disease: a new concept of etiology. 547-58 Altemeier W A WA Hill E O EO Fullen W D WD eng Journal Article United States Ann Surg 0372354 0003-4932 9005-49-6 Heparin AIM IM Acute Disease Adult Aged Bacteroides Chronic Disease Female Fusobacterium Infections complications Heparin administration & dosage (...) therapeutic use Humans Infection microbiology L Forms pathogenicity Male Middle Aged Peptostreptococcus Pregnancy Pulmonary Embolism etiology Staphylococcal Infections complications Streptococcal Infections complications Thromboembolism etiology microbiology Thrombophlebitis etiology microbiology Varicose Veins complications 1969 10 1 1969 10 1 0 1 1969 10 1 0 0 ppublish 5344031 PMC1387770 Surgery. 1951 Aug;30(2):298-310 14855228 J Bacteriol. 1941 Mar;41(3):301-3 16560400 J Bacteriol. 1964 Dec;88:1805-7

1969 Annals of Surgery

177. Puerperal thromboembolic disease. Full Text available with Trip Pro

Puerperal thromboembolic disease. 4739604 1973 05 24 2018 11 13 0007-1447 1 5853 1973 Mar 10 British medical journal Br Med J Puerperal thromboembolic disease. 614 Taylor A B AB eng Journal Article England Br Med J 0372673 0007-1447 0 Iodine Radioisotopes AIM IM Animals Breast Female Humans Iodine Radioisotopes Milk Pregnancy Puerperal Disorders Radionuclide Imaging Thromboembolism diagnosis 1973 3 10 1973 3 10 0 1 1973 3 10 0 0 ppublish 4739604 PMC1589897 Br J Surg. 1968 Oct;55(10):742-7

1973 British medical journal

178. An analysis of the reported association of oral contraceptives to thromboembolic disease. Full Text available with Trip Pro

An analysis of the reported association of oral contraceptives to thromboembolic disease. 1089003 1975 03 18 2018 11 13 0093-0415 122 1 1975 Jan The Western journal of medicine West. J. Med. An analysis of the reported association of oral contraceptives to thromboembolic disease. 26-33 Odell W D WD eng Journal Article Review United States West J Med 0410504 0093-0415 0 Contraceptives, Oral 0 Estrogens 731DCA35BT Diethylstilbestrol 88181ACA0M Norethynodrel B2V233XGE7 Mestranol IM Adolescent (...) Adult Cerebrovascular Disorders chemically induced Contraceptives, Oral adverse effects Diethylstilbestrol adverse effects therapeutic use Estrogens administration & dosage adverse effects therapeutic use Female Humans Intracranial Embolism and Thrombosis chemically induced mortality Male Mestranol adverse effects Myocardial Infarction chemically induced Norethynodrel adverse effects Pregnancy Prostatic Neoplasms drug therapy Pulmonary Embolism chemically induced mortality Recurrence Retrospective

1975 Western Journal of Medicine

179. Pulmonary Disease and Pregnancy (Diagnosis)

and respiratory muscle function in pregnancy. Am Rev Respir Dis . 1991 Oct. 144(4):837-41. . Crapo RO. Normal cardiopulmonary physiology during pregnancy. Clin Obstet Gynecol . 1996 Mar. 39(1):3-16. . Cydulka RK, Emerman CL, Schreiber D, Molander KH, Woodruff PG, Camargo CA Jr. Acute asthma among pregnant women presenting to the emergency department. Am J Respir Crit Care Med . 1999 Sep. 160(3):887-92. . Douketis JD, Ginsberg JS. Diagnostic problems with venous thromboembolic disease in pregnancy. Haemostasis (...) . 1995 Jan-Apr. 25(1-2):58-71. . Elkus R, Popovich J Jr. Respiratory physiology in pregnancy. Clin Chest Med . 1992 Dec. 13(4):555-65. . Ginsberg JS, Hirsh J, Rainbow AJ, Coates G. Risks to the fetus of radiologic procedures used in the diagnosis of maternal venous thromboembolic disease. Thromb Haemost . 1989 Apr 25. 61(2):189-96. . King TE Jr. Restrictive lung disease in pregnancy. Clin Chest Med . 1992 Dec. 13(4):607-22. . Laibl VR, Sheffield JS. Influenza and pneumonia in pregnancy. Clin

2014 eMedicine.com

180. Pulmonary Disease and Pregnancy (Follow-up)

and respiratory muscle function in pregnancy. Am Rev Respir Dis . 1991 Oct. 144(4):837-41. . Crapo RO. Normal cardiopulmonary physiology during pregnancy. Clin Obstet Gynecol . 1996 Mar. 39(1):3-16. . Cydulka RK, Emerman CL, Schreiber D, Molander KH, Woodruff PG, Camargo CA Jr. Acute asthma among pregnant women presenting to the emergency department. Am J Respir Crit Care Med . 1999 Sep. 160(3):887-92. . Douketis JD, Ginsberg JS. Diagnostic problems with venous thromboembolic disease in pregnancy. Haemostasis (...) . 1995 Jan-Apr. 25(1-2):58-71. . Elkus R, Popovich J Jr. Respiratory physiology in pregnancy. Clin Chest Med . 1992 Dec. 13(4):555-65. . Ginsberg JS, Hirsh J, Rainbow AJ, Coates G. Risks to the fetus of radiologic procedures used in the diagnosis of maternal venous thromboembolic disease. Thromb Haemost . 1989 Apr 25. 61(2):189-96. . King TE Jr. Restrictive lung disease in pregnancy. Clin Chest Med . 1992 Dec. 13(4):607-22. . Laibl VR, Sheffield JS. Influenza and pneumonia in pregnancy. Clin

2014 eMedicine.com

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