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Syrup of Ipecac

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81. Toxicity, Antihistamine (Follow-up)

them down the toilet. Medication should be considered "medicine," not a toy or candy. Medicine should never be referred to as candy and, if possible, not administered in front of other children. Parents, relatives, and friends also should childproof their homes. Although ipecac syrup has fallen into disfavor in some medical circles, it is still recommended that parents have it readily available in the home for use with medical direction from a physician or poison control center. In instances

2014 eMedicine Emergency Medicine

82. Toxicity, Ciguatera (Follow-up)

== processing > Ciguatera Toxicity Treatment & Management Updated: Dec 29, 2015 Author: Thomas C Arnold, MD, FAAEM, FACMT; Chief Editor: Asim Tarabar, MD Share Email Print Feedback Close Sections Sections Ciguatera Toxicity Treatment Approach Considerations Treatment is largely supportive and symptom driven. If performed within 3-4 hours of toxin ingestion, gastric decontamination with activated charcoal may help. Avoid administering ipecac syrup because of its potential to worsen fluid losses. Antiemetics

2014 eMedicine Emergency Medicine

83. Disk Battery Ingestion (Overview)

, no clinical evidence of mercury toxicity was observed. [ ] A spent cell, which no longer has enough power for the intended device, may still maintain considerable residual voltage. However, new cells are 3.2 times likely to be associated with clinically significant outcomes than spent cells. [ ] Retrograde movement of the battery from the stomach to the esophagus has been reported as a complication of use of ipecac syrup, necessitating emergent endoscopic removal. If the battery produces a mucosal burn

2014 eMedicine Emergency Medicine

84. Toxicity, Iron (Overview)

Toxicol (Phila) . 2018 Dec 21. 55 (10):1-203. . . [Guideline] Höjer J, Troutman WG, Hoppu K, Erdman A, Benson BE, Mégarbane B, et al. Position paper update: ipecac syrup for gastrointestinal decontamination. Clin Toxicol (Phila) . 2013 Mar. 51(3):134-9. . Tenenbein M. Benefits of parenteral deferoxamine for acute iron poisoning. J Toxicol Clin Toxicol . 1996. 34(5):485-9. . Sankar J, Shukla A, Khurana R, Dubey N. Near fatal iron intoxication managed conservatively. BMJ Case Rep . 2013 Jan 31. 2013

2014 eMedicine Emergency Medicine

85. Guidelines for the management of paracetamol poisoning in Australia and New Zealand - explanation and elaboration

with potential accidental paracetamol intoxication, gastrointestinal decontamination with syrup of ipecac, activated charcoal or gastric lavage is not indicated. In adults, activated charcoal administered within 1–2 hours of ingestion reduces the absorbed paracetamol dose and the likelihood that N -acetylcysteine will subsequently be required. Nevertheless, if activated charcoal cannot be administered, treatment with N -acetylcysteine within 8 hours guarantees survival in any case. Therefore, activated

2008 MJA Clinical Guidelines

86. Home safety education and provision of safety equipment for injury prevention (Review).

), and for those interventions not providing safety equipment (IRR 0.78, 95% CI 0.66 to 0.92). Home safety interventions were effective in increasing the proportion of families with safe hot tap water temperatures (OR 1.41, 95% CI 1.07 to 1.86), functional smoke alarms (OR 1.81, 95% CI 1.30 to 2.52), a fire escape plan (OR 2.01, 95% CI 1.45 to 2.77), storing medicines (OR 1.53, 95% CI 1.27 to 1.84) and cleaning products (OR 1.55, 95% CI 1.22 to 1.96) out of reach, having syrup of ipecac (OR 3.34, 95% CI 1.50

2013 Evidence-based child health : a Cochrane review journal

87. Home safety education and provision of safety equipment for injury prevention. (PubMed)

), and for those interventions not providing safety equipment (IRR 0.78, 95% CI 0.66 to 0.92).Home safety interventions were effective in increasing the proportion of families with safe hot tap water temperatures (OR 1.41, 95% CI 1.07 to 1.86), functional smoke alarms (OR 1.81, 95% CI 1.30 to 2.52), a fire escape plan (OR 2.01, 95% CI 1.45 to 2.77), storing medicines (OR 1.53, 95% CI 1.27 to 1.84) and cleaning products (OR 1.55, 95% CI 1.22 to 1.96) out of reach, having syrup of ipecac (OR 3.34, 95% CI 1.50

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2012 Cochrane database of systematic reviews (Online)

88. Toxicity of Weight Loss Agents (PubMed)

Toxicity of Weight Loss Agents With the rise of the obesity epidemic in the United States over the last several decades and the medical complications seen with it, weight loss and dieting have become a national public health concern.Because of their increased use and availability through internet sales, several different dieting agents were reviewed for potential toxicity. These included: syrup of ipecac, cathartics, human chorionic gonadotropin hormone, 2,4 Dinitrophenol, guar gum

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2012 Journal of Medical Toxicology

89. Emergency treatment of petroleum distillate and turpentine ingestion (PubMed)

Emergency treatment of petroleum distillate and turpentine ingestion A comparative study was made of pulmonary complications following the use of ipecac syrup and gastric lavage for hydrocarbon ingestion. The selected 255 patients had chest radiography when first seen and again two to five days later. Of these patients 74 or 29% had been treated with ipecac syrup, 41 or 16% by gastric lavage. On follow-up radiographs 19% of the ipecac-treated group were unchanged or worsened, compared with 39 (...) % of the lavage group, suggesting that pneumonitis was significantly less severe in the ipecac-treated patients. Use of ipecac is preferred over gastric lavage for alert patients who have ingested an excessive amount of hydrocarbon.

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1974 Canadian Medical Association Journal

90. Prevention of Poisoning (PubMed)

Prevention of Poisoning Education of the public in prevention of accidental poisoning has been unsuccessful. The use of child-resistant containers for prescription drugs, patent medicines and household products is the most promising approach to this problem. The value of Syrup of Ipecac is stressed to induce early emesis, following ingestion of poisons. Medication errors in hospital are another serious cause of accidental poisoning and various examples are discussed. Every physician must take

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1974 Canadian Family Physician

91. General Principles of Poisoning

and, if a caustic substance has been ingested, is contraindicated (see ). If gastric emptying is used, gastric lavage is the preferred method. Gastric lavage may cause complications such as epistaxis, aspiration, or, rarely, oropharyngeal or esophageal injury. Syrup of ipecac has unpredictable effects, often causes prolonged vomiting, and may not remove substantial amounts of poison from the stomach. Syrup of ipecac may be warranted if the ingested agent is highly toxic and transport time to the emergency

2013 Merck Manual (19th Edition)

92. Cough in Adults

). Dextromethorphan , a congener of the opioid levorphanol , is effective as a tablet or syrup at a dose of 15 to 30 mg po 1 to 4 times/day for adults or 0.25 mg/kg po qid for children. Codeine has antitussive, analgesic, and sedative effects, but dependence is a potential problem, and nausea, vomiting, constipation, and tolerance are common adverse effects. Usual doses are 10 to 20 mg po q 4 to 6 h as needed for adults and 0.25 to 0.5 mg/kg po qid for children. Other opioids (hydrocodone, hydromorphone (...) , methadone , morphine ) have antitussive properties but are avoided because of high potential for dependence and abuse. Benzonatate , a congener of tetracaine that is available in liquid-filled capsules, is effective at a dose of 100 to 200 mg po tid. Expectorants are thought to decrease viscosity and facilitate expectoration (coughing up) of secretions but are of limited, if any, benefit in most circumstances. Guaifenesin (200 to 400 mg po q 4 h in syrup or tablet form) is most commonly used because

2013 Merck Manual (19th Edition)

93. Bulimia Nervosa

, the stomach ruptures or the esophagus is torn during a binge or purge episode, leading to life-threatening complications. Because substantial weight loss does not occur, the serious physical complications that often occur with anorexia nervosa are not present. However, cardiomyopathy may result from long-term abuse of syrup of ipecac if used to induce vomiting. Symptoms and Signs Patients with bulimia nervosa typically describe binge-purge behavior. Binges involve rapid consumption of an amount of food

2013 Merck Manual (19th Edition)

94. Paracetamol toxicity

charcoal. Inducing vomiting with has no role in paracetamol overdose because the vomiting it induces delays the effective administration of activated charcoal and oral acetylcysteine. Liver injury is extremely rare after acute accidental ingestion in children under 6 years of age. Children with accidental exposures do not require gastrointestinal decontamination with either gastric lavage, activated charcoal, or syrup of ipecac. Acetylcysteine [ ] is the antidote for paracetamol toxicity , also called

2012 Wikipedia

95. Poison

; European Association of Poisons Centres Clinical Toxicologists (2004). "Position paper: Ipecac syrup". J Toxicol Clin Toxicol . 42 (2): 133–143. : . . Vale JA, Kulig K; American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologist. (2004). "Position paper: gastric lavage". J Toxicol Clin Toxicol . 42 (7): 933–943. : . . CS1 maint: Multiple names: authors list ( ) "Position paper: whole bowel irrigation". J Toxicol Clin Toxicol . 42 (6): 843–854. 2004

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2012 Wikipedia

96. Effect of education and safety equipment on poisoning-prevention practices and poisoning: systematic review, meta-analysis and meta-regression (PubMed)

by child age, gender and social variables.Home safety interventions increased safe storage of medicines (OR 1.57, 95% CI 1.22 to 2.02) and cleaning products (OR 1.63, 95% CI 1.22 to 2.17), the possession of syrup of ipecac (OR 3.34, 95% CI 1.50 to 7.41), and having poison control centre numbers accessible (OR 3.67, 95% CI 1.84 to 7.33). There was a lack of evidence on poisoning rates (rate ratio 1.03, 95% CI 0.78 to 1.36) and no consistent evidence that intervention effects differed by child age

2008 EvidenceUpdates

97. Comparative efficacy of maropitant and selected drugs in preventing emesis induced by centrally or peripherally acting emetogens in dogs. (PubMed)

Comparative efficacy of maropitant and selected drugs in preventing emesis induced by centrally or peripherally acting emetogens in dogs. Maropitant (Cerenia; a novel, selective neurokinin(1) receptor antagonist), chlorpromazine, metoclopramide and ondansetron were compared in two randomized, placebo-controlled studies for efficacy in preventing emesis induced by emetogens acting centrally (apomorphine; Study 1) or peripherally (syrup of ipecac; Study 2) in dogs. In each study, ten male and ten (...) female beagles were treated in a five-treatment, five-period crossover design. The five treatments were 0.9% saline (0.1 mL/kg), maropitant (1 mg/kg), metoclopramide (0.5 mg/kg), or chlorpromazine (0.5 mg/kg) all administered subcutaneously, or ondansetron (0.5 mg/kg) administered intravenously. One hour posttreatment dogs were challenged with apomorphine at 0.1 mg/kg intravenously (Study 1) or syrup of ipecac at 0.5 mL/kg orally (Study 2). Following emetogen challenge, dogs were observed for 30 min

2008 Journal of veterinary pharmacology and therapeutics

98. Gastrointestinal decontamination of the poisoned patient. (PubMed)

of syrup of ipecac-induced emesis, orogastric lavage, single-dose-activated charcoal, cathartics, and whole-bowel irrigation.

2008 Pediatric Emergency Care

99. Home safety education and provision of safety equipment for injury prevention. (PubMed)

1.22 to 2.17) out of reach, syrup of ipecac (OR 3.34, 95% CI 1.50 to 7.44) and poison control centre numbers accessible (OR 3.66, 95% CI 1.84 to 7.27), fitted stair gates (1.26, 95% CI 1.05 to 1.51), socket covers on unused sockets (OR 3.73, 95% CI 1.48 to 9.39) and storing sharp objects out of reach (OR 1.52, 95% CI 1.01 to 2.29). There was a lack of evidence that interventions reduced rates of thermal injuries, poisoning or a range of injuries. There was no consistent evidence that interventions

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2007 Cochrane

100. Home safety education and provision of safety equipment for injury prevention. (PubMed)

1.22 to 2.17) out of reach, syrup of ipecac (OR 3.34, 95% CI 1.50 to 7.44) and poison control centre numbers accessible (OR 3.66, 95% CI 1.84 to 7.27), fitted stair gates (1.26, 95% CI 1.05 to 1.51), socket covers on unused sockets (OR 3.73, 95% CI 1.48 to 9.39) and storing sharp objects out of reach (OR 1.52, 95% CI 1.01 to 2.29). There was a lack of evidence that interventions reduced rates of thermal injuries, poisoning or a range of injuries. There was no consistent evidence that interventions

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2007 Cochrane database of systematic reviews (Online)

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