How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

204 results for

Sydenham Chorea

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

181. Is there any advice in someone wishing to become pregnant with a prior history of Sydenham's chorea?

Is there any advice in someone wishing to become pregnant with a prior history of Sydenham's chorea? Is there any advice in someone wishing to become pregnant with a prior history of Sydenham's chorea? - Trip Database or use your Google+ account Find evidence fast ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe (...) across other content types including images, videos, patient information leaflets, educational courses and news. For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com Is there any advice in someone wishing to become pregnant with a prior history of Sydenham's chorea? Unfortunately, we have been unable to locate any evidence to support your management. eMedicine has

2007 TRIP Answers

182. Randomized double-blind study with prednisone in Sydenham's chorea. (PubMed)

Randomized double-blind study with prednisone in Sydenham's chorea. In this randomized, double-blind, parallel study of a group of 22 children and teenagers, prednisone efficacy in acute Sydenham's chorea was assessed. Use of prednisone (2 mg/kg/day during 4 weeks, followed by a gradual discontinuation) in the 22 patients and in a placebo group (n = 15) was evaluated by a chorea intensity score based on presence, distribution, and interference of choreic movement on daily activities. Each (...) patient was evaluated by the same pediatric neurologist weekly during the first month, followed by evaluation on weeks 8 and 12, with further evaluations as necessary if choreic movements persisted. Although initial chorea intensity was similar in both groups, a significant difference was observed after 1 week of medication (P < 0.001) with a larger reduction in the prednisone group, that continued until the end of the study. Percentage decrease in chorea intensity scale score also was persistently

2006 Pediatric neurology

183. Treatment of Sydenham's chorea with intravenous immunoglobulin, plasma exchange, or prednisone. (PubMed)

Treatment of Sydenham's chorea with intravenous immunoglobulin, plasma exchange, or prednisone. Sydenham's chorea has been established as a postinfectious autoimmune neuropsychiatric disorder. Corticosteroids have been used to treat patients with severe disease but are not always effective, and relapses are frequent after cessation. Eighteen subjects were entered into this randomized-entry controlled trial designed to determine if intravenous immunoglobulin or plasma exchange would be superior (...) to prednisone in decreasing the severity of chorea. Mean chorea severity for the entire group was significantly lower at the 1-month follow-up evaluation (overall 48% improvement). Although the between-group differences were not statistically significant, clinical improvements appeared to be more rapid and robust in the intravenous immunoglobulin and plasma exchange groups than in the prednisone group (mean chorea severity scores decreased by 72% in the intravenous immunoglobulin group, 50% in the plasma

2005 Journal of child neurology

184. Sydenham's chorea in western Pennsylvania. (PubMed)

Sydenham's chorea in western Pennsylvania. Chorea is characterized by involuntary, fleeting, irregular, nonrhythmic movements that flow from 1 body region to another. There are many causes of childhood chorea, including cerebrovascular accidents, collagen vascular diseases, drug intoxication, hyperthyroidism, Wilson's disease, Huntington's disease, and infectious agents. Although Sydenham's chorea (SC), a nonsuppurative sequela of group A streptococcal infection, is known to be a common cause (...) of chorea, multiple laboratory and radiographic studies are often obtained to determine the cause of pediatric chorea. We conducted a retrospective chart review to determine the causes of childhood chorea seen in a large children's hospital in an area endemic for acute rheumatic fever (ARF). The utility of neuroimaging in establishing a final diagnosis of SC is discussed.Patients who received a diagnosis of chorea between 1980 and 2004 at the Children's Hospital of Pittsburgh were identified from

2006 Pediatrics

185. Nerve conduction study in Sydenham's chorea. (PubMed)

Nerve conduction study in Sydenham's chorea. Sydenham's chorea (SC) is a late complication of group A beta-hemolytic streptococci infection presumably caused by an abnormal autoimmune reaction. Despite rare case reports of peripheral neuropathy associated with streptococcal infection, there is no investigation of peripheral nerve in SC. We performed nerve conduction studies in a cohort of patients with SC. The neurophysiology investigation comprised measurement of amplitude and sensory

2005 Movement Disorders

186. UFMG Sydenham's chorea rating scale (USCRS): reliability and consistency. (PubMed)

UFMG Sydenham's chorea rating scale (USCRS): reliability and consistency. Despite the renewed interest in Sydenham's chorea (SC) in recent years, there were no valid and reliable scales to rate the several signs and symptoms of patients with SC and related disorders. The Universidade Federal de Minas Gerais (UFMG) Sydenham's Chorea Rating Scale (USCRS) was designed to provide a detailed quantitative description of the performance of activities of daily living, behavioral abnormalities

2005 Movement Disorders

187. Serum from Sydenham's chorea patients modifies intracellular calcium levels in PC12 cells by a complement-independent mechanism. (PubMed)

Serum from Sydenham's chorea patients modifies intracellular calcium levels in PC12 cells by a complement-independent mechanism. The proposed pathogenesis of Sydenham's chorea (SC) is an autoantibody-mediated basal ganglia dysfunction. Our study has shown that incubation of PC12 cells with complement-inactivated serum from SC patients was associated with a significant increase in Ca2+ levels evoked by KCl stimulus (mean +/- SEM, 341.0 +/- 8.7% of fluorescence intensity, arbitrary units) when

2005 Movement Disorders

188. Recurrence of Sydenham chorea: implications for pathogenesis. (PubMed)

Recurrence of Sydenham chorea: implications for pathogenesis. Sydenham chorea (SC), a major sign of rheumatic fever (RF), is related to systemic streptococcal infection and is treated with antibiotics. Recurrence usually occurs within a short interval following the initial event and is considered part of RF.To evaluate the rate, nature, and course of recurrent SC during an extended follow-up period.Prospective assessment of a cohort of patients with SC who were admitted between 1985 and 2002 (...) .General community hospital.Diagnosis of RF was based on the revised Jones criteria. Other causes of chorea were excluded. Recurrence was defined as the development of new signs, lasting more than 24 hours and separated by a minimum of 2 months from the previous episode. Patients were observed from 1 to 14 years following the initial SC episode and for at least 1 year after recurrence. At recurrence, patients were assessed for RF clinical and laboratory activity, including change in cardiac

Full Text available with Trip Pro

2004 Archives of Neurology

189. Late recurrences of Sydenham's chorea are not associated with anti-basal ganglia antibodies. (PubMed)

Late recurrences of Sydenham's chorea are not associated with anti-basal ganglia antibodies. Anti-basal ganglia antibodies (ABGA) have been associated with 100% of acute cases and 69% of persistent cases of Sydenham's chorea. We describe two cases of late recurrences of Sydenham's chorea with absence of ABGA. Both patients had several childhood episodes of Sydenham's chorea. MRI imaging of the basal ganglia and exhaustive investigations for other causes of chorea were normal or negative

Full Text available with Trip Pro

2004 Neurosurgery and Psychiatry

190. Obsessive-compulsive symptoms in adults with history of rheumatic fever, Sydenham's chorea and type I diabetes mellitus: preliminary results. (PubMed)

Obsessive-compulsive symptoms in adults with history of rheumatic fever, Sydenham's chorea and type I diabetes mellitus: preliminary results. Rheumatic fever (RF) associated with Sydenham's chorea (a neurological variant of RF), but not RF without chorea, has been acutely related to obsessive-compulsive symptomatology/disorder (OCS/OCD). This study investigated the presence of OCS in adults who had RF with or without chorea in childhood.The Yale-Brown Obsessive-Compulsive Scale (Y-BOCS (...) ) was used to evaluate OCS in 38 adults with history of RF (13 with chorea; 25 without chorea) or diabetes (controls; n = 19).The OCS was similar in both groups, although the intensity of symptoms was not clinically relevant. Moreover, subjects with RF with or without chorea did not score differently in the Y-BOCS.The similar occurrence of OCS in patients with history of RF and diabetes suggests that the development of this symptomatology, triggered by group A beta-haemolytic streptococcus infections

2005 Acta Psychiatrica Scandinavica

191. Treatment of Sydenham chorea with corticosteroids. (PubMed)

Treatment of Sydenham chorea with corticosteroids. Despite treatment with valproic acid and neuroleptics, a significant proportion of patients with Sydenham chorea (SC) remain with chorea. We evaluated the effect of intravenous methyl-prednisolone followed by oral prednisone in patients with SC refractory to conventional treatment. Patients were enrolled in the study if they failed to improve with conventional treatment, despite the development of side effects. Chorea was rated on a 0 to 4 (...) score. Five patients, 3 of them women, were included in the study. The median pretreatment rating score of the chorea was 3 (range, 3-4) and dropped to 1 (range, 0-2) after a median follow-up of 7 months (range, 3-7 months). Two patients developed Cushing syndrome. Our data suggest that intravenous methyl-prednisolone followed by oral prednisone is an effective and well-tolerated treatment of refractory SC.

2003 Movement Disorders

192. Did Gustav Mahler have Sydenham's chorea? (PubMed)

Did Gustav Mahler have Sydenham's chorea? Sydenham's chorea (SC), a major manifestation of acute rheumatic fever (RF), is characterized by chorea and other motor and non-motor features. Among the latter are behavioral symptoms, including obsessive-compulsive disorder. Although SC is typically a self-limited condition, up to 50% of patients may evolve with persistent chorea. There is evidence that Gustav Mahler had a movement disorder, but its nature remains undetermined. There are witnesses (...) describing him as having facial dyskinesia and a gait disorder consistent with chorea. His conducting performance was notorious for obsessive attention to details of the staging and musical production. Mahler was diagnosed with a valvulopathy in 1907 and died of subacute bacterial endocarditis in 1911. It is possible that the composer suffered from RF in childhood with carditis and SC, which may left him with valvulopathy, obsessive-compulsive disorder, and persistent chorea.

2006 Movement Disorders

193. Obsessive-compulsive spectrum disorders in rheumatic fever with and without Sydenham's chorea. (PubMed)

Obsessive-compulsive spectrum disorders in rheumatic fever with and without Sydenham's chorea. Recent findings suggest that acute-phase rheumatic fever (RF) patients present with higher frequencies of obsessive-compulsive disorder (OCD) and tic disorders. Until now, there have been no such studies in RF in non-acute phases.To verify whether patients with a history of RF with or without Sydenham's chorea (SC) present with higher rates of OCD, tic disorders, and other obsessive-compulsive (OC

2004 Journal of Clinical Psychiatry

194. Obsessive compulsive behavior, hyperactivity, and attention deficit disorder in Sydenham chorea. (PubMed)

Obsessive compulsive behavior, hyperactivity, and attention deficit disorder in Sydenham chorea. The authors investigated obsessive-compulsive behavior, obsessive-compulsive disorder (OCD), and attention deficit and hyperactivity disorder (ADHD) in 50 healthy subjects, 50 patients with rheumatic fever without chorea, and 56 patients with Sydenham chorea. Obsessive-compulsive behavior, OCD, and ADHD were more frequent in the Sydenham chorea group (19%, 23.2%, 30.4%) than in the healthy subjects (...) (11%, 4%, 8%) and in the rheumatic fever without chorea group (14%, 6%, 8%). ADHD was more common in persistent Sydenham chorea.

2005 Neurology

195. Tracing Sydenham's chorea: historical documents from a British paediatric hospital. (PubMed)

Tracing Sydenham's chorea: historical documents from a British paediatric hospital. Sydenham's chorea (SC) became a well defined nosological entity only during the second half of the nineteenth century. Such progress was promoted by the availability of large clinical series provided by newly founded paediatric hospitals. This paper analyses the demographic and clinical features of patients with chorea admitted to the first British paediatric hospital (the Hospital for Sick Children, Great

Full Text available with Trip Pro

2005 Archives of Disease in Childhood

196. Sydenham chorea: a case report and review of the literature. (PubMed)

Sydenham chorea: a case report and review of the literature. Sydenham chorea (SC) is the neurological manifestation of rheumatic fever and is the most common acquired chorea in children. The disease presents as choreiform movements and behavioral changes after a streptoccocal throat infection. Although the incidence of SC has diminished because of aggressive antibiotic treatment, both isolated cases and epidemics persist, necessitating emergency physicians to be familiar with the disease. We

2007 Pediatric Emergency Care

197. Corticosteroids i Sydenham's chorea. (PubMed)

Corticosteroids i Sydenham's chorea. 7203571 1981 05 21 2013 04 18 0971-5916 72 1980 Nov The Indian journal of medical research Indian J. Med. Res. Corticosteroids i Sydenham's chorea. 696-701 Kalra V V Ghai O P OP eng Clinical Trial Journal Article Randomized Controlled Trial India Indian J Med Res 0374701 0971-5916 0 Adrenal Cortex Hormones IM Adrenal Cortex Hormones therapeutic use Brain Diseases etiology Child Child, Preschool Chorea drug therapy etiology Female Humans Male Rheumatic Fever

1981 The Indian journal of medical research

198. Homovanilic acid in Huntington's disease and Sydenham's chorea. (PubMed)

Homovanilic acid in Huntington's disease and Sydenham's chorea. Homovanilic acid (HVA) was determined in the lumbar CSF of 12 patients with Huntington's disease and 12 with Sydenham's chorea before and after probenecid administration. The means of HVA concentration (basal and after probenecid) were lower in those with Huntington's disease than in controls, and were even lower in a sub-group characterised by increased tone and slowness of voluntary movement. There was no correlation between CSF (...) HVA values and the severity of abnormal movements, nor with length of the illness and age of the patients with Huntington's disease. The mean basal HVA concentration did not differ from controls in those with Sydenham's chorea but the accumulation with probenecid was significantly lower. These results suggest a decrease in cerebral dopamine release in both forms of chorea.

Full Text available with Trip Pro

1981 Journal of neurology, neurosurgery, and psychiatry

199. Successful treatment of refractory Sydenham's chorea with pimozide. (PubMed)

Successful treatment of refractory Sydenham's chorea with pimozide. 3998747 1985 07 17 2018 11 13 0022-3050 48 4 1985 Apr Journal of neurology, neurosurgery, and psychiatry J. Neurol. Neurosurg. Psychiatry Successful treatment of refractory Sydenham's chorea with pimozide. 390 Harries-Jones R R Gibson J G JG eng Case Reports Letter England J Neurol Neurosurg Psychiatry 2985191R 0022-3050 1HIZ4DL86F Pimozide IM Adolescent Chorea drug therapy Humans Male Pimozide therapeutic use 1985 4 1 1985 4 1

Full Text available with Trip Pro

1985 Journal of neurology, neurosurgery, and psychiatry

200. SPECT and MRI findings in Sydenham's chorea. (PubMed)

SPECT and MRI findings in Sydenham's chorea. 8006668 1994 07 15 2018 11 13 0022-3050 57 6 1994 Jun Journal of neurology, neurosurgery, and psychiatry J. Neurol. Neurosurg. Psychiatry SPECT and MRI findings in Sydenham's chorea. 763 Hill A A Herkes G K GK Roche P P eng Case Reports Comment Letter England J Neurol Neurosurg Psychiatry 2985191R 0022-3050 IM J Neurol Neurosurg Psychiatry. 1992 Mar;55(3):238-9 1564496 Adult Chorea diagnosis etiology Female Humans Magnetic Resonance Imaging Rheumatic

Full Text available with Trip Pro

1994 Journal of neurology, neurosurgery, and psychiatry

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>