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41. Treatment of superficial thrombophlebitis: a randomized, bouble-blind trial of heparinoid cream. (PubMed)

Treatment of superficial thrombophlebitis: a randomized, bouble-blind trial of heparinoid cream. In a prospective, double-blind, randomized trial the efficacy of a heparinoid in ointment form was assessed in treating superficial thrombophlebitis developing after continuous intravenous infusion. One hundred surgical patients were studied, and clinical examination and the iodine-125-labelled fibrinogen test used to assess the results. The mean time required for the relief of local symptoms

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1975 British medical journal Controlled trial quality: uncertain

42. Idiopathic superficial thrombophlebitis and the incidence of cancer in primary care patients (PubMed)

Idiopathic superficial thrombophlebitis and the incidence of cancer in primary care patients The association of spontaneous venous thromboembolism with occult malignancy is well established. Less clear is the incidence of subsequent cancer in patients with superficial thrombophlebitis. We wanted to determine the incidence of cancer after an episode of spontaneous superficial thrombophlebitis in a large general practice population.The objective of this study was to assess the incidence of newly (...) diagnosed malignancies in patients within 2 years after the diagnosis of a spontaneous episode of superficial thrombophlebitis and to compare this incidence with nonexposed matched control patients and the Dutch population. The patients and their controls were identified by a search in the electronic patient records of 5 primary health care centers in Amsterdam, the Netherlands. A standardized morbidity ratio was calculated using data of the Dutch cancer registry.A total number of 277 patients

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2010 EvidenceUpdates

43. Effect of PEM Treatment of Superficial Axial and Tributary Vein Reflux on Improvement of Wound Healing in VLUs

pain/discomfort in extremity, infusion site thrombosis (retained coagulum), injection site hematoma or pain, and superficial thrombophlebitis. Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below (...) Effect of PEM Treatment of Superficial Axial and Tributary Vein Reflux on Improvement of Wound Healing in VLUs Effect of PEM Treatment of Superficial Axial and Tributary Vein Reflux on Improvement of Wound Healing in VLUs - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved

2016 Clinical Trials

44. Postoperative Massive Pulmonary Embolism Due to Superficial Vein Thrombosis of the Upper Limb (PubMed)

extremities deep vein thrombosis) is a very rare clinical manifestation with few cases reported in the literature. We report a rare case of thrombophlebitis in departure from a superficial branch of the cephalic vein of the right arm, complicated by cardiac arrest secondary to a massive pulmonary embolism in a patient who underwent major surgery for ovarian cancer. We discuss on the numerous thrombotic risk factors, triggering a cascade of reactions and resulting in a potential fatal clinical (...) Postoperative Massive Pulmonary Embolism Due to Superficial Vein Thrombosis of the Upper Limb It is well known that deep vein thrombosis of the upper extremities is linked to high morbidity/mortality, resulting in 12-20% of all documented pulmonary embolism; however, there are few data about thromboembolism originating from a vein and/or a branch of a superficial vein of the upper extremities. Pulmonary embolism secondary to upper limb superficial vein thrombosis (not combined with upper

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2016 Journal of clinical medicine research

45. Randomized trial of radiofrequency ablation versus conventional surgery for superficial venous insufficiency: if you don't tell, they won't know. (PubMed)

Randomized trial of radiofrequency ablation versus conventional surgery for superficial venous insufficiency: if you don't tell, they won't know. This study compared radiofrequency ablation versus conventional surgery in patients who had not undergone previous treatment for bilateral great saphenous vein insufficiency, with each patient serving as his own control.This was a randomized controlled trial that included 18 patients and was carried out between November 2013 and May 2015. Each (...) of the lower limbs of each patient was randomly assigned to undergo either radiofrequency ablation or conventional surgery. Clinical features (hyperpigmentation, hematoma, aesthetics, pain, skin burn, nerve injury, and thrombophlebitis) were evaluated at one week, one month, and six months postoperatively. Hemodynamic assessments (presence of resection or occlusion of the great saphenous vein and recurrent reflux in the sapheno-femoral junction and in the great saphenous vein) were performed at one month

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2016 Clinics (Sao Paulo, Brazil) Controlled trial quality: uncertain

46. Cerebral tubercular thrombophlebitis presenting as venous infarct: Magnetic resonance imaging and pathologic correlation (PubMed)

proven cases of tuberculous thrombophlebitis with venous infarcts involving superficial venous system in one and deep venous system in the other. This is the first study presenting radiopathologic correlation of this rare complication. Tuberculous thrombophlebitis should be suspected if basal exudates and multiple white matter T2 hyperintensities are seen on neuroimaging and the imaging protocol should include both magnetic resonance arteriogram and venogram. (...) Cerebral tubercular thrombophlebitis presenting as venous infarct: Magnetic resonance imaging and pathologic correlation Central nervous system involvement by tuberculosis to produce basal meningitis, hydrocephalus, arteritis and infarcts is well-known, the brunt of the pathology being borne by the arterial vasculature to produce neurological sequelae. However, tuberculous thrombophlebitis causing venous infarction is exceedingly rare. We present imaging and pathological features of two autopsy

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2014 Annals of Indian Academy of Neurology

47. Thrombophlebitis (Treatment)

combinations than prophylactic doses. [ ] LMWH and nonsteroidal anti-inflammatory drugs (NSAIDs) both were shown to decrease the incidence of thrombophlebitis spread by approximately 70% in a meta-analysis of 24 studies and nearly 2500 patients. [ ] In a small study of 72 patients, LMWH (dalteparin) was found to be superior to NSAIDs (ibuprofen) in preventing extension of DVT. [ ] Alternatively, superficial relapsing superficial venous thrombophlebitis may be treated with subcutaneously placed fondaparinux (...) , diagnosis, and treatment of thrombosis. Am J Surg . 1990 Dec. 160(6):547-51. . Kakkar VV, Howe CT, Nicolaides AN, Renney JT, Clarke MB. Deep vein thrombosis of the leg. Is there a "high risk" group?. Am J Surg . 1970 Oct. 120(4):527-30. . Samlaska CP, James WD. Superficial thrombophlebitis. II. Secondary hypercoagulable states. J Am Acad Dermatol . 1990 Jul. 23(1):1-18. . Schafer AI. The hypercoagulable states. Ann Intern Med . 1985 Jun. 102(6):814-28. . Chengelis DL, Bendick PJ, Glover JL, Brown OW

2014 eMedicine.com

48. Thrombophlebitis (Overview)

. The hypercoagulable condition of the immediate antepartum period is responsible, in large part, for the development of superficial thrombophlebitis and DVT in 0.15% and 0.04% of this patient population, respectively. [ ] Even more important is the immediate postpartum period, during which the incidences of superficial thrombophlebitis and DVT increase to 1.18% and 0.15%, respectively. A Dutch study of pregnant women with age-matched controls found a 5-fold increased risk of venous thrombosis during pregnancy (...) thrombophlebitis of the superficial veins of the breast and anterior chest wall. It has been associated with breast or axillary surgery, malignancy, and intense thoracoabdominal exercise training. [ , ] Previous Next: Etiology See . Trauma to a varicose vein or healthy vein is common. Predisposing factors include any event that can reduce venous flow; examples include prolonged sitting or immobilization and dehydration (eg, as on a long airline flight), long surgery, or prolonged bed rest. Genetic

2014 eMedicine.com

49. Thrombophlebitis (Follow-up)

combinations than prophylactic doses. [ ] LMWH and nonsteroidal anti-inflammatory drugs (NSAIDs) both were shown to decrease the incidence of thrombophlebitis spread by approximately 70% in a meta-analysis of 24 studies and nearly 2500 patients. [ ] In a small study of 72 patients, LMWH (dalteparin) was found to be superior to NSAIDs (ibuprofen) in preventing extension of DVT. [ ] Alternatively, superficial relapsing superficial venous thrombophlebitis may be treated with subcutaneously placed fondaparinux (...) , diagnosis, and treatment of thrombosis. Am J Surg . 1990 Dec. 160(6):547-51. . Kakkar VV, Howe CT, Nicolaides AN, Renney JT, Clarke MB. Deep vein thrombosis of the leg. Is there a "high risk" group?. Am J Surg . 1970 Oct. 120(4):527-30. . Samlaska CP, James WD. Superficial thrombophlebitis. II. Secondary hypercoagulable states. J Am Acad Dermatol . 1990 Jul. 23(1):1-18. . Schafer AI. The hypercoagulable states. Ann Intern Med . 1985 Jun. 102(6):814-28. . Chengelis DL, Bendick PJ, Glover JL, Brown OW

2014 eMedicine.com

50. Deep Venous Thrombosis and Thrombophlebitis (Follow-up)

to effective compression is strongly recommended. Early ambulation without ECS is not recommended. The fear of dislodging clots and precipitating a fatal PE is unfounded. Previous Next: Treatment of Superficial Thrombophlebitis Superficial thrombophlebitis is often associated with deep venous thrombosis (DVT) in two specific settings. The following high-risk groups require further evaluation for DVT: Superficial thrombophlebitis in the absence of coexisting venous varices and no other obvious etiology (...) Involvement of the greater saphenous vein above the knee, especially if it extends to the saphenofemoral junction (These latter patients should be treated as having proximal vein DVT and treated with full anticoagulant therapy.) Uncomplicated superficial thrombophlebitis may be treated symptomatically with heat, nonsteroidal anti-inflammatory agents (NSAIDs), and compression hose. Bed rest is not recommended. Some centers recommend full anticoagulation for high-risk patients with isolated superficial

2014 eMedicine Emergency Medicine

51. Thrombophlebitis, Septic (Diagnosis)

develop spontaneously but more often is associated with breaks in the skin. Though most commonly caused by indwelling catheters, septic thrombophlebitis may also result from simple procedures such as venipuncture for phlebotomy and intravenous injection. While infection must always be considered, catheter-related phlebitis can result from sterile chemical or mechanical irritation. (See Etiology.) Septic phlebitis of a superficial vein without frank purulence is known as simple phlebitis. Simple (...) phlebitis is often benign, but when it is progressive, it can cause serious complications, and even death. Suppurative superficial thrombophlebitis is a more serious condition that can lead to and death, even with appropriate aggressive intervention. [ ] A frequent complication is embolization of infected thrombus to distant sites, most commonly the lungs, leading to septic pulmonary emboli, hypoxia, sepsis, and often death. [ ] Patient factors such as burns, [ ] steroid usage, [ ] or intravenous drug

2014 eMedicine Emergency Medicine

52. Deep Venous Thrombosis and Thrombophlebitis (Overview)

Deep Venous Thrombosis and Thrombophlebitis (Overview) Deep Venous Thrombosis (DVT): Practice Essentials, Background, Anatomy Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTkxMTMwMy1vdmVydmlldw== processing (...) that is easily displaced. These suprafascial collecting veins can dilate to accommodate large volumes of blood with little increase in back pressure so that the volume of blood sequestered within the venous system at any moment can vary by a factor of 2 or more without interfering with the normal function of the veins. Suprafascial collecting veins belong to the superficial venous system. Outflow from collecting veins is via secondary conduit veins that have thicker walls and are less distensible. Most

2014 eMedicine Emergency Medicine

53. Thrombophlebitis (Diagnosis)

. The hypercoagulable condition of the immediate antepartum period is responsible, in large part, for the development of superficial thrombophlebitis and DVT in 0.15% and 0.04% of this patient population, respectively. [ ] Even more important is the immediate postpartum period, during which the incidences of superficial thrombophlebitis and DVT increase to 1.18% and 0.15%, respectively. A Dutch study of pregnant women with age-matched controls found a 5-fold increased risk of venous thrombosis during pregnancy (...) thrombophlebitis of the superficial veins of the breast and anterior chest wall. It has been associated with breast or axillary surgery, malignancy, and intense thoracoabdominal exercise training. [ , ] Previous Next: Etiology See . Trauma to a varicose vein or healthy vein is common. Predisposing factors include any event that can reduce venous flow; examples include prolonged sitting or immobilization and dehydration (eg, as on a long airline flight), long surgery, or prolonged bed rest. Genetic

2014 eMedicine.com

54. Thrombophlebitis, Septic (Treatment)

Thrombophlebitis, Septic (Treatment) Septic Thrombophlebitis Treatment & Management: Approach Considerations, Emergency and Inpatient Department Care, Consultations Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvNzg2NTI2LXRyZWF0bWVudA== processing > Septic Thrombophlebitis Treatment & Management Updated: Dec 07, 2018 Author: Nicholas J Connors, MD; Chief Editor: Jeter (Jay) Pritchard Taylor, III, MD Share Email Print Feedback Close Sections Sections Septic Thrombophlebitis Treatment Approach Considerations Given the rarity of septic thrombophlebitis, as well as the wide variety of vessels involved and the substantial morbidity and mortality, a very high index of suspicion should be maintained by the ED physician

2014 eMedicine Emergency Medicine

55. Vasculitis and Thrombophlebitis (Overview)

vascular involvement in 14% of patients with Behçet disease, most commonly manifesting as superficial vein thrombophlebitis or deep vein thrombosis. [ ] Previous Next: Pathophysiology Vessel inflammation occurs by various mechanisms in this heterogenous group of diseases. The histopathological pattern of inflammation is a characteristic feature of the vasculitis subtypes. Lymphocytic/giant cell-mediated vasculitis Takayasu arteritis and temporal arteritis (in adults) both involve large elastic arteries (...) Vasculitis and Thrombophlebitis (Overview) Vasculitis and Thrombophlebitis: Background, Classification Guidelines, The EULAR and PRES Classification of Childhood Vasculitis Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache

2014 eMedicine Pediatrics

56. Vasculitis and Thrombophlebitis (Diagnosis)

vascular involvement in 14% of patients with Behçet disease, most commonly manifesting as superficial vein thrombophlebitis or deep vein thrombosis. [ ] Previous Next: Pathophysiology Vessel inflammation occurs by various mechanisms in this heterogenous group of diseases. The histopathological pattern of inflammation is a characteristic feature of the vasculitis subtypes. Lymphocytic/giant cell-mediated vasculitis Takayasu arteritis and temporal arteritis (in adults) both involve large elastic arteries (...) Vasculitis and Thrombophlebitis (Diagnosis) Vasculitis and Thrombophlebitis: Background, Classification Guidelines, The EULAR and PRES Classification of Childhood Vasculitis Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache

2014 eMedicine Pediatrics

57. Deep Venous Thrombosis and Thrombophlebitis (Diagnosis)

Deep Venous Thrombosis and Thrombophlebitis (Diagnosis) Deep Venous Thrombosis (DVT): Practice Essentials, Background, Anatomy Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTkxMTMwMy1vdmVydmlldw== processing (...) that is easily displaced. These suprafascial collecting veins can dilate to accommodate large volumes of blood with little increase in back pressure so that the volume of blood sequestered within the venous system at any moment can vary by a factor of 2 or more without interfering with the normal function of the veins. Suprafascial collecting veins belong to the superficial venous system. Outflow from collecting veins is via secondary conduit veins that have thicker walls and are less distensible. Most

2014 eMedicine Emergency Medicine

58. Thrombophlebitis, Septic (Overview)

as severe systemic infections culminating in profound that is refractory to aggressive management, including operative intervention and intensive care. (See Presentation and Prognosis.) A number of distinct clinical conditions have been identified, depending on the vessel involved, but all thrombophlebitides involve the same basic pathophysiology. Thrombosis and infection within a vein can occur throughout the body and can involve superficial or deep vessels. Notable examples are thrombophlebitis (...) but more often is associated with breaks in the skin. Though most commonly caused by indwelling catheters, septic thrombophlebitis may also result from simple procedures such as venipuncture for phlebotomy and intravenous injection. While infection must always be considered, catheter-related phlebitis can result from sterile chemical or mechanical irritation. (See Etiology.) Septic phlebitis of a superficial vein without frank purulence is known as simple phlebitis. Simple phlebitis is often benign

2014 eMedicine Emergency Medicine

59. Deep Venous Thrombosis and Thrombophlebitis (Treatment)

to effective compression is strongly recommended. Early ambulation without ECS is not recommended. The fear of dislodging clots and precipitating a fatal PE is unfounded. Previous Next: Treatment of Superficial Thrombophlebitis Superficial thrombophlebitis is often associated with deep venous thrombosis (DVT) in two specific settings. The following high-risk groups require further evaluation for DVT: Superficial thrombophlebitis in the absence of coexisting venous varices and no other obvious etiology (...) Involvement of the greater saphenous vein above the knee, especially if it extends to the saphenofemoral junction (These latter patients should be treated as having proximal vein DVT and treated with full anticoagulant therapy.) Uncomplicated superficial thrombophlebitis may be treated symptomatically with heat, nonsteroidal anti-inflammatory agents (NSAIDs), and compression hose. Bed rest is not recommended. Some centers recommend full anticoagulation for high-risk patients with isolated superficial

2014 eMedicine Emergency Medicine

60. Thrombophlebitis, Septic (Follow-up)

Thrombophlebitis, Septic (Follow-up) Septic Thrombophlebitis Treatment & Management: Approach Considerations, Emergency and Inpatient Department Care, Consultations Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvNzg2NTI2LXRyZWF0bWVudA== processing > Septic Thrombophlebitis Treatment & Management Updated: Dec 07, 2018 Author: Nicholas J Connors, MD; Chief Editor: Jeter (Jay) Pritchard Taylor, III, MD Share Email Print Feedback Close Sections Sections Septic Thrombophlebitis Treatment Approach Considerations Given the rarity of septic thrombophlebitis, as well as the wide variety of vessels involved and the substantial morbidity and mortality, a very high index of suspicion should be maintained by the ED physician

2014 eMedicine Emergency Medicine

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