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Superficial Thrombophlebitis

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181. Diagnosis of Mondor's Disease in the Emergency Department with Bedside Ultrasound (PubMed)

Diagnosis of Mondor's Disease in the Emergency Department with Bedside Ultrasound Mondor's disease is a rare condition characterized by a superficial thrombophlebitis that can occur in the thoracoabdominal and genital areas. Findings with ultrasound in penile Mondor's disease are readily measurable: a noncompressible penile vein without flow and absence of tears of the corpus cavernosum or tunica albuginea, hematoma, or evidence of fracture of the penis. We present a case of Mondor's disease

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2015 Case Reports in Emergency Medicine

182. Human placenta-derived cells (PDA-001) for the treatment of adults with multiple sclerosis: A randomized, placebo-controlled, multiple-dose study. (PubMed)

anaphylactoid reaction and 1 had grade 2 superficial thrombophlebitis. Other adverse events were mild to moderate and included headache, fatigue, infusion site reactions, and urinary tract infection.PDA-001 infusions were safe and well tolerated in relapsing-remitting multiple sclerosis and secondary progressive multiple sclerosis patients. No paradoxical worsening of lesion counts was noted with either dose.Copyright © 2014 The Authors. Published by Elsevier B.V. All rights reserved.

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2015 Multiple sclerosis and related disorders Controlled trial quality: predicted high

183. Prophylaxis of Ileostomy Closure Site Hernia by Placing Mesh

independently. Respiratory complications [ Time Frame: 30 days after surgery ] Pneumonia, Atelectasis, Pulmonary embolism, Respiratory distress syndrome ... This is a Clinical measure always supported by image . All the morbidity problems are reported independently. Vascular Complications [ Time Frame: 30 days after surgery ] Deep venous thrombosis, phlebitis, thrombophlebitis, ... This is a Clinical measure supported by more specific test if necessary . All the morbidity problems are reported independently (...) disorientation. Local infection [ Time Frame: 30 days after surgery ] Superficial, deep, body-cavity This is a Clinical measure supported by image if necessary All the morbidity problems are reported independently Local complications [ Time Frame: 30 days after surgery ] Hematoma, seroma, evisceration This is a Clinical measure All the morbidity problems are reported independently Hospital stay [ Time Frame: Days ] Hospital stay since surgery is done Eligibility Criteria Go to Information from the National

2014 Clinical Trials

184. Estradiol Vaginal Softgel Capsules in Treating Symptoms of Vulvar and Vaginal Atrophy in Postmenopausal Women

Capsule Drug: Estradiol Experimental: Estradiol 25mcg Vaginal Softgel Capsule Estradiol 25mcg Vaginal Softgel Capsule Drug: Estradiol Placebo Comparator: Placebo Vaginal Softgel Capsule Placebo Vaginal Softgel Capsule Drug: Placebo Outcome Measures Go to Primary Outcome Measures : Co-Primary Efficacy Endpoint - Vaginal Superficial Cells [ Time Frame: Baseline and 12 Weeks ] • Change from Baseline to Week 12 in the percentage of vaginal superficial cells (by vaginal cytologic smear) compared to placebo (...) from Baseline to Week 12 on the severity of the MBS of dyspareunia (vaginal pain associated with sexual activity) associated with VVA as compared to placebo VVA Symptoms Self-Assessment Questionnaire Severity Scale: 0 = None, 1 = Mild, 2 = Moderate, 3 = Severe. Subjects assessed severity at Baseline and Week 12 Secondary Outcome Measures : Secondary Efficacy Endpoints - Vaginal Superficial Cells [ Time Frame: Baseline and Week 2 ] • Change from Baseline to Week 2 in the percentage of vaginal

2014 Clinical Trials

185. Single Dose vs. Two Dose Regimen of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections

to be resistant to dalbavancin or vancomycin (vancomycin MIC (minimum inhibitory concentration) >8 μg/mL). Evidence of meningitis, necrotizing fasciitis, gas gangrene, gangrene, septic arthritis, osteomyelitis; endovascular infection, such as clinical and/or echocardiographic evidence of endocarditis or septic thrombophlebitis. Infections caused exclusively by Gram-negative bacteria (without Gram-positive bacteria present) and infections caused by fungi, whether alone or in combination with a bacterial (...) as assessed by a vascular surgeon. Participants with ABSSSI such as superficial/simple cellulitis/erysipelas, impetiginous lesion, furuncle, or simple abscess that only requires surgical drainage for cure. Concomitant condition requiring any antibiotic therapy that would interfere with the assessment of study drug for the condition under study. Anticipated need of antibiotic therapy for longer than 14 days. Participants who are placed in a hyperbaric chamber as adjunctive therapy for the ABSSSI. More than

2014 Clinical Trials

186. Penile Mondor’s disease (PubMed)

Penile Mondor’s disease Mondor's disease is a rare, self-limiting, benign process with acute presentation characterized by subcutaneous bands in several parts of the body. Penile Mondor's disease (PMD) is thrombophlebitis of the superficial dorsal vein of the penis. It is usually considered as thrombophlebitis or phlebitis of subcutaneous vessels. Some findings suggest that it might be of lymphatic origin. The chest, abdominal wall, penis, upper arm, and other parts of the body may also (...) be involved by the disease. Although its physiopathology is not exactly known, transection of the vessel during surgery or any type of trauma such as external compression may trigger its possible development. This disease almost always limits itself. It may be associated with psychological distress and sexual incompatibility. The patients usually feel the superficial vein of the penis like a hard rope and present with complaint of pain around this hardness. Diagnosis is usually easy with physical

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2014 Basic and Clinical Andrology

187. Achieving predictability in augmentation mastopexy. (PubMed)

documented.At a mean follow-up of 38 months, major complications included 16 revisions and one readmission for superficial thrombophlebitis. The majority of revisions were for scar revision or implant size change. Minor complications included two hematomas, one seroma, three T-point skin sloughs, and two minor infections. There were no instances of major flap loss or nipple loss.The technique described provides a safe and conservative surgical approach for one-stage augmentation mastopexy resulting

2014 Plastic and reconstructive surgery

188. The VANISH-2 study: a randomized, blinded, multicenter study to evaluate the efficacy and safety of polidocanol endovenous microfoam 0.5% and 1.0% compared with placebo for the treatment of saphenofemoral junction incompetence. (PubMed)

emboli were detected and no clinically important neurologic or visual adverse events were reported. The most common adverse events in patients treated with polidocanol endovenous microfoam were retained coagulum, leg pain and superficial thrombophlebitis; most were related to treatment and resolved without sequelae.Polidocanol endovenous microfoam provided clinically meaningful benefit in treating symptoms and appearance in patients with varicose veins. Polidocanol endovenous microfoam

2014 Phlebology / Venous Forum of the Royal Society of Medicine Controlled trial quality: uncertain

191. Nonneoplastic Epithelial Disorders of the Vulva (Overview)

a pseudomembranous coating. Vulvar ulcers, ranging in diameter from a few millimeters to 3 cm, often appear as multiple crops of well-defined and very tender ulcers with fibrinous bases and considerable undermining. Fistulae, with partial or complete destruction of the labia, may develop. Other manifestations of the disease include fever, malaise, acneiform lesions or cutaneous nodules on the skin, arthritis, synovitis, and thrombophlebitis. Associated erythema nodosum and erythema multiforme have been reported (...) ). Lymphangioma This condition is usually detected early in infancy on the labia minora or majora as an asymptomatic, raised, compressible, doughy mass, sometimes showing multiple clustered, superficial, thin-walled, translucent, and persistent pseudovesicles filled with clear fluid that may progressively grow over time. [ ] Angiokeratoma Angiokeratomas manifest as 1-3 mm, dark, red-to-purple, and sometimes hyperkeratotic papules. Patients are usually asymptomatic. Benign vulvar lesions. Angiokeratomas

2014 eMedicine.com

192. Normal and Abnormal Puerperium (Overview)

superficial injury to the skin and subcutaneous perineal tissue or vaginal epithelium only. Second degree lacerations extend into the musculature of the perineal body, including the deep and superficial transverse perineal muscles, the bulbocavernosus muscle, and the pubococcygeus muscle. Obstetric anal sphincter injuries (OASIS), which are third and fourth degree perineal lacerations are considered more severe forms of obstetric tears. Third degree lacerations extend beyond the muscles and involve (...) and mortality Following 48-72 hours of intravenous antibiotic therapy, 90% of women clinically improve. Fewer than 2% of patients develop life-threatening complications such as septic shock, pelvic abscess, or septic pelvic thrombophlebitis. [ ] History A patient may report any of the following symptoms: fever, chills, lower abdominal pain, malodorous lochia, increased vaginal bleeding, anorexia, and malaise. Physical A focused physical examination is important and should include vital signs, an examination

2014 eMedicine.com

193. Erysipelas (Overview)

: Loretta S Davis, MD; Chief Editor: William D James, MD Share Email Print Feedback Close Sections Sections Erysipelas Overview Background Erysipelas is a bacterial skin infection involving the upper dermis that characteristically extends into the superficial cutaneous lymphatics. It is a tender, intensely erythematous, indurated plaque with a sharply demarcated border. Its well-defined margin can help differentiate it from other skin infections (eg, cellulitis). [ ] See the image below. (See .) Well (...) usually are not life threatening, and most cases resolve after antibiotic therapy without sequelae. (The disease may also resolve spontaneously, without treatment.) Complications of erysipelas may include the following: Gangrene/amputation Chronic edema Scarring Bacteremia sepsis Scarlet fever Pneumonia Abscess [ , ] Embolism Meningitis Death The most common complications of erysipelas include abscess, gangrene, and thrombophlebitis. [ ] Less common complications (< 1%) are acute glomerulonephritis

2014 eMedicine.com

194. Benign Vulvar Lesions (Follow-up)

a pseudomembranous coating. Vulvar ulcers, ranging in diameter from a few millimeters to 3 cm, often appear as multiple crops of well-defined and very tender ulcers with fibrinous bases and considerable undermining. Fistulae, with partial or complete destruction of the labia, may develop. Other manifestations of the disease include fever, malaise, acneiform lesions or cutaneous nodules on the skin, arthritis, synovitis, and thrombophlebitis. Associated erythema nodosum and erythema multiforme have been reported (...) ). Lymphangioma This condition is usually detected early in infancy on the labia minora or majora as an asymptomatic, raised, compressible, doughy mass, sometimes showing multiple clustered, superficial, thin-walled, translucent, and persistent pseudovesicles filled with clear fluid that may progressively grow over time. [ ] Angiokeratoma Angiokeratomas manifest as 1-3 mm, dark, red-to-purple, and sometimes hyperkeratotic papules. Patients are usually asymptomatic. Benign vulvar lesions. Angiokeratomas

2014 eMedicine.com

195. Behcet Disease (Follow-up)

showing pulmonary artery aneurysm in a Behçet disease patient. Courtesy of Mohanad Elfishawi, MD, Rheumatology Department, Cairo University. Acneiform lesions in a Behçet disease patient. Courtesy of Mohanad Elfishawi, MD, Rheumatology Department, Cairo University. Superficial thrombophlebitis in a Behçet disease patient. Courtesy of Mohanad Elfishawi, MD, Rheumatology Department, Cairo University. Postphlebitic limb in a Behçet disease patient. Courtesy of Mohanad Elfishawi, MD, Rheumatology

2014 eMedicine.com

196. Deep Venous Thrombosis (Diagnosis)

displaced. These suprafascial collecting veins can dilate to accommodate large volumes of blood with little increase in back pressure so that the volume of blood sequestered within the venous system at any moment can vary by a factor of 2 or more without interfering with the normal function of the veins. Suprafascial collecting veins belong to the superficial venous system. Outflow from collecting veins is via secondary conduit veins that have thicker walls and are less distensible. Most of these veins (...) driving the blood proximally. When the calf is allowed to relax, the veins and sinusoids refill from the superficial venous system via perforating veins, and the outflow valve is then forced shut, preventing retrograde flow. With each “contraction,” 40-60% of the calf’s venous volume is driven proximally. [ ] The deep veins of the thigh begin distally with the popliteal vein as it courses proximally behind the knee and then passes through the adductor canal, at which point its name changes

2014 eMedicine Surgery

197. Chronic Venous Insufficiency (Diagnosis)

that DVT affected 1.3% of patients and that amputation was necessary in 1.2%, with an overall mortality of 1.6%. [ ] As many as 50% of patients with untreated varicose veins develop superficial thrombophlebitis at some time. This is of grave concern, because unrecognized DVT is present in as many as 45% of patients with what appears to be purely superficial phlebitis. The risk of DVT is 3 times higher in patients with superficial varicosities than in the general population. Bed rest and intercurrent (...) : Oct 22, 2018 Author: Robert Weiss, MD; Chief Editor: William D James, MD Share Email Print Feedback Close Sections Sections Venous Insufficiency Overview Background In venous insufficiency states, venous blood escapes from its normal antegrade path of flow and refluxes backward down the veins into an already congested leg. Venous insufficiency syndromes are most commonly caused by valvular incompetence in the low-pressure superficial venous system (see the image below) but may also be caused

2014 eMedicine Surgery

198. Buerger Disease (Thromboangiitis Obliterans) (Diagnosis)

. Although patient's right foot is normal in gross appearance, angiography demonstrated compromised arterial flow to both feet. Superficial thrombophlebitis of great toe in patient with thromboangiitis obliterans (Buerger disease). Tobacco smoke stains on male patient's fingers suggest diagnosis of thromboangiitis obliterans (Buerger disease). Patient presented with small, painful ulcers on tips of thumb and ring finger. Lower-extremity arteriogram of peroneal and tibial arteries of patient (...) with thromboangiitis obliterans (Buerger disease) demonstrates classic findings of multiple small and medium-sized arterial occlusions with formation of compensatory "corkscrew collaterals." of 4 Tables ] Table 1. Scoring System for Diagnosis of Thromboangiitis Obliterans [ ] Positive Criterion Positive Points Age at onset < 30 y (+2) 30-40 y (+1) Foot intermittent claudication Present (+2) By history only (+1) Upper extremity Symptomatic (+2) Asymptomatic (+1) Migrating superficial thrombophlebitis Present (+2

2014 eMedicine Surgery

199. Tumescent Liposuction (Overview)

to the deepest layer in a radial fashion and then successively more superficially. Infiltration of anesthetic is achieved with an electric-powered peristaltic pump. Some physicians prefer to use a spinal needle for infiltration without regard to specific insertion sites. Although the addition of hyaluronidase may hasten the diffusion of anesthetic, this addition may allow for increased absorption, different peak levels, and duration of anesthetic effect. The addition of corticosteroid is also avoided because (...) emboli, viscus perforation, thrombophlebitis, hypovolemic shock, seizures, or toxic reactions were described. Four cases of toxic shock syndrome were recognized, but, overall, the prevalence of infection ranged from 0.34-0.6%. Skin irregularity ranged from 0.26-2.1%. The rate of hematoma or seroma was only 0.17-1.6%, the rate of unacceptable scarring was 0.02%, the rate of sensory nerve impairment was 0.03-2.6%, and the rate of contact dermatitis was 0.12%. In another recent survey of 261

2014 eMedicine.com

200. Campylobacter Infections (Overview)

. Such adherence would promote gut colonization. PEB 1 is a superficial antigen that appears to be a major adhesin and is conserved among C jejuni strains. Some strains of C jejuni produce a heat-labile, choleralike enterotoxin, which is important in the watery diarrhea observed in infections. Infection with the organism produces diffuse, bloody, edematous, and exudative enteritis. The inflammatory infiltrate consists of neutrophils, mononuclear cells, and eosinophils. Crypt abscesses develop in the epithelial (...) in Campylobacter jejuni. Antimicrob Agents Chemother . 2008 Nov. 52(11):3947-54. . Carbone KM, Heinrich MC, Quinn TC. Thrombophlebitis and cellulitis due to Campylobacter fetus ssp. fetus. Report of four cases and a review of the literature. Medicine (Baltimore) . 1985 Jul. 64(4):244-50. . Crushell E, Harty S, Sharif F, Bourke B. Enteric campylobacter: purging its secrets?. Pediatr Res . 2004 Jan. 55(1):3-12. . Drake AA, Gilchrist MJ, Washington JA 2nd, et al. Diarrhea due to Campylobacter fetus subspecies

2014 eMedicine.com

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