How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

298 results for

Subungual Melanoma

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

1. Collision of subungual melanoma and subungual squamous cell carcinoma: a case series. (Abstract)

Collision of subungual melanoma and subungual squamous cell carcinoma: a case series. Subungual squamous cell carcinoma (SSCC) and subungual melanoma (SUM) are rare tumors. Several case reports of association of SSCC with SUM (SSCC-SUM) have been published.We sought to document the clinical, dermoscopic, and histologic features in a case series of SSCC-SUMs and describe their relative frequency compared with those of SSCC and SUM.All patients who underwent surgical exploration of the nail

2017 Journal of American Academy of Dermatology

2. Subungual melanoma: A retrospective cohort of 157 cases from Brazilian National Cancer Institute. (Abstract)

Subungual melanoma: A retrospective cohort of 157 cases from Brazilian National Cancer Institute. Subungual melanoma (SM) is rare. The lesions are thick at the time of diagnosis. Few studies have evaluated SM in Brazil.The objective of this study was to investigate the factors associated with the survival of SM patients from the Brazilian National Cancer Institute.One-hundred and fifty-seven patients diagnosed with SM were included in this study. We evaluated the epidemiologic, clinical

2018 Journal of Surgical Oncology

3. Subungual Amelanotic Melanoma Masquerading as Onychomycosis Full Text available with Trip Pro

Subungual Amelanotic Melanoma Masquerading as Onychomycosis Subungual amelanotic melanoma is rare. In addition, amelanotic melanoma can mimic non-melanocytic tumors. A 67-year-old woman had a four-year history of dystrophy of the left fourth fingernail. Periodic acid-Schiff staining of the nail plate demonstrated fungal hyphae, establishing a diagnosis of tinea unguium. The nail plate subsequently detached and the underlying nail bed showed a red, friable mass that was biopsied and confirmed (...) a diagnosis of melanoma. In conclusion, additional morphologic change of a persistent nail dystrophy-even with a biopsy-confirmed diagnosis of onychomycosis-may require consideration for repeat evaluation, including a biopsy, to exclude the possibility of a subungual malignant tumor.

2018 Cureus

4. Assessment of a Predictive Scoring Model for Dermoscopy of Subungual Melanoma In Situ. Full Text available with Trip Pro

Assessment of a Predictive Scoring Model for Dermoscopy of Subungual Melanoma In Situ. Subungual melanoma in situ (SMIS) is a malignant neoplasm that requires early diagnosis and complete surgical excision; however, little is known about the usefulness of the detailed dermoscopic features of longitudinal melanonychia (LM) to predict the diagnosis of SMIS.To investigate the characteristic dermoscopic findings of SMIS and to establish a predictive scoring model for the diagnosis of SMIS

2018 JAMA dermatology (Chicago, Ill.)

5. Subungual Melanoma of the Hand. (Abstract)

Subungual Melanoma of the Hand. The diagnosis of subungual melanoma (SUM) can be challenging and SUMs generally have a worse prognosis than melanomas arising elsewhere. Due to their rarity, the evidence to guide management is limited. This study sought to identify clinicopathological features predictive of outcome and to provide guidelines for management.From a large, single-institution database, 103 patients with in situ (n = 9) or invasive (n = 94) SUMs of the hand treated between 1953 (...) (SNB), 28% of which were positive. Forty percent of SNB-positive patients had involved non-sentinel nodes (SNs) in their completion lymph node dissection. Five-year melanoma-specific survival (MSS) and disease-free survival (DFS) rates were 70% and 52%, respectively. On multivariate analysis, regional node metastasis and right-hand tumor location were significant predictors of shorter DFS and MSS, whereas mitoses negatively impacted DFS only and increasing Breslow thickness impacted MSS only.This

2018 Annals of Surgical Oncology

6. Early Detection of Subungual Melanoma In Situ: Proposal of ABCD Strategy in Clinical Practice Based on Case Series Full Text available with Trip Pro

Early Detection of Subungual Melanoma In Situ: Proposal of ABCD Strategy in Clinical Practice Based on Case Series Prevalence of subungual melanoma (SUM) in Asian population is relatively high and early clinical detection improves both quality of life and survival.We sought to establish screening strategy for SUM in situ.We retrospectively reviewed medical records of 8 patients pathologically diagnosed as SUM in situ between January 2015 and September 2016.All patients in our study were adults (...) and had solitary lesion. In all cases, longitudinal melanonychia as well as background pigmentation in entire nail plate was observed. Seven (87.5%) cases had periungual pigmentation. Clinical features of SUM in situ can be summarized according to new criteria categorized under initial letters of alphabet, namely nail ABCD of SUM in situ; "A" stands for adult age (age >18 years); "B" for brown bands in brown background; "C" for color in periungual skin; "D" for one digit. Our strategy was to suspect

2017 Annals of dermatology

7. Super-thin SCIP Flap for Reconstruction of Subungual Melanoma: Aesthetic Functional Surgery. (Abstract)

Super-thin SCIP Flap for Reconstruction of Subungual Melanoma: Aesthetic Functional Surgery. This study aimed to use a superthin, free superficial circumflex iliac artery perforator (SCIP) flap in functional surgery for treating subungual melanoma and to evaluate its outcomes.Forty-one patients with primary subungual melanoma of less than or equal to 2-mm thickness who were treated with functional surgery were prospectively enrolled. After oncologic resection, a thin SCIP flap was harvested (...) Function Index following functional surgery were significantly lower than those following amputation.The superthin SCIP flap might serve as a valuable reconstruction option, providing aesthetically thin coverage and reliable outcomes, in functional surgery for treating early-stage subungual melanoma.Therapeutic, IV.

2017 Plastic and reconstructive surgery

8. A Case of Subungual Melanoma In Situ in an 18-Year-Old Girl Presented with Total Melanonychia Full Text available with Trip Pro

A Case of Subungual Melanoma In Situ in an 18-Year-Old Girl Presented with Total Melanonychia 28966533 2018 11 13 1013-9087 29 5 2017 Oct Annals of dermatology Ann Dermatol A Case of Subungual Melanoma In Situ in an 18-Year-Old Girl Presented with Total Melanonychia. 653-654 10.5021/ad.2017.29.5.653 Woo Cheong Ha CH Department of Dermatology, Ilsan Paik Hospital, College of Medicine, Inje University, Goyang, Korea. Ham Seung Pil SP Department of Dermatology, Ilsan Paik Hospital, College

2017 Annals of dermatology

9. Digit preserving surgery of subungual melanoma, a case series using vacuum assisted closure and full thickness skin grafting. (Abstract)

Digit preserving surgery of subungual melanoma, a case series using vacuum assisted closure and full thickness skin grafting. 28609554 2017 12 27 1468-3083 31 12 2017 Dec Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol Digit preserving surgery of subungual melanoma: a case series using vacuum assisted closure and full-thickness skin grafting. e537-e538 10.1111/jdv.14400 Crisan D D Department of Dermatology & Allergology, University of Ulm

2017 Journal of the European Academy of Dermatology and Venereology

10. Frequency of Subungual Melanoma in Longitudinal Melanonychia: A Single-Center Experience. (Abstract)

Frequency of Subungual Melanoma in Longitudinal Melanonychia: A Single-Center Experience. Clinical and dermatoscopic guidelines are used to differentiate between benign longitudinal melanonychia (LM) and subungual melanoma; however, the frequency of malignancy among patients undergoing a biopsy for LM is not well defined.To describe the histologic diagnoses and malignancy among patients undergoing a biopsy for clinical LM.Retrospective cohort study of consecutive patients who underwent a nail (...) biopsy for LM at a single cancer center between 2000 and 2014. Clinical features, biopsy techniques, and histopathologic results were reviewed.Forty-two patients with 43 biopsied lesions were included. Three of the 43 biopsies revealed melanoma (mean depth 2.1 mm). The mean age among patients with malignant lesions was 60 years compared with 58.1 years for benign lesions. The mean width of all biopsied lesions was 4.2 mm, with a mean of 10.7 mm for malignant and 3.4 mm for benign. The first digit

2017 Dermatologic Surgery

11. Subungual Melanoma

Subungual Melanoma Subungual Melanoma Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Subungual Melanoma Subungual Melanoma Aka (...) : Subungual Melanoma , Ungual Melanoma , Hutchinson Nail Sign , Hutchinson's Nail Sign , Hutchinson's Melanotic Whitlow , Acral Lentiginous Melanoma From Related Chapters II. Epidemiology Represents 2.5% of s Account for 50% of s in dark skinned patients III. Pathophysiology Type of Acral Lentiginous Melanoma IV. Characteristics Longitudinal brown-black streak May encompass entire nail Hutchinson's Nail Sign affecting proximal nail fold skin V. Evaluation: Factors suggesting Melanoma Recent change (e.g

2018 FP Notebook

12. A case of nodular subungual melanoma without Hutchinson's nail sign. (Abstract)

A case of nodular subungual melanoma without Hutchinson's nail sign. An early and accurate diagnosis is critical for the optimal management of subungual melanoma; the absence of Hutchinson's nail sign makes an accurate diagnosis extremely difficult. Previous publications show that most subungual melanomas have Hutchinson's nail sign. In this report, we present a rare case of a subungual melanoma without Hutchinson's nail sign and discuss the importance of cautious evaluations of Hutchinson's

2016 Australasian Journal of Dermatology

13. Population-based incidence and melanoma-specific survival of cutaneous malignant melanoma in a Colombian population 2000-2009. (Abstract)

Population-based incidence and melanoma-specific survival of cutaneous malignant melanoma in a Colombian population 2000-2009. Demographic, clinical, and morphological characteristics of cutaneous melanoma are unknown for the Colombian population. We aim to provide these characteristics as well as population-based incidence and survival data.All patients with an invasive cutaneous melanoma diagnosed in the period 2000-2009 registered in the population-based cancer registry of the metropolitan (...) of melanomas presented on the plants or palms (16%) and under the nails (7.1%); at least 24.3% of melanomas were ulcerated, and 21.1% had a Breslow thickness more than 2 mm. Melanoma-specific 5-year survival was 79.3%, with worst survival for melanomas localized on the plants (64.6%) and subungual areas (55.6%). Affiliation to the subsidized type of affiliation to the social security system was statistically significantly (P = 0.003) associated with poorer survival (68.8%) compared to the special regimes

2017 International Journal of Dermatology

14. Non-melanoma Hutchinson's sign: A reappraisal of this important, remarkable melanoma simulant. (Abstract)

Non-melanoma Hutchinson's sign: A reappraisal of this important, remarkable melanoma simulant. More than 20 years ago, our reappraisal of the Hutchinson's sign (HS) gave birth to the concept of the pseudo-Hutchinson's sign.We have found it interesting to emphasize some important histologic points and to expand the list of the numerous HS simulants.We have examined the cutaneous samples taken from the pigmented skin of patients in association with nail matrix biopsy. We have also extended (...) , involvement of the PNF, nail matrix and nail bed containing atypical melanocytes in irregular array may be seen in more advanced lesions. The recent literature on non-melanoma HS simulants is summarized and clinical examples are provided.The mere presence of periungual pigmentation is neither clinically nor histologically pathognomonic of subungual melanoma and justifies the usefulness of this work stressing the non-melanoma HS.© 2017 European Academy of Dermatology and Venereology.

2017 Journal of the European Academy of Dermatology and Venereology

15. Variable Sized Cellular Remnants in the Nail Plate of Longitudinal Melanonychia: Evidence of Subungual Melanoma Full Text available with Trip Pro

Variable Sized Cellular Remnants in the Nail Plate of Longitudinal Melanonychia: Evidence of Subungual Melanoma 26082594 2015 06 17 2018 11 13 1013-9087 27 3 2015 Jun Annals of dermatology Ann Dermatol Variable Sized Cellular Remnants in the Nail Plate of Longitudinal Melanonychia: Evidence of Subungual Melanoma. 328-9 10.5021/ad.2015.27.3.328 Lee Dong-Youn DY Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. eng Journal Article 2015 05

2015 Annals of dermatology

16. Melanoma Treatment (PDQ®): Health Professional Version

in the skin, they may also arise from mucosal surfaces or at other sites to which neural crest cells migrate, including the uveal tract. Uveal melanomas differ significantly from cutaneous melanoma in incidence, prognostic factors, molecular characteristics, and treatment. (Refer to the PDQ summary on for more information.) Incidence and Mortality Estimated new cases and deaths from melanoma in the United States in 2019:[ ] New cases: 96,480. Deaths: 7,230. Skin cancer is the most common malignancy (...) diagnosed in the United States, with 5.4 million cancers diagnosed among 3.3 million people in 2012.[ ] Invasive melanoma represents about 1% of skin cancers but results in most deaths.[ , ] The incidence has been increasing over the past 30 years.[ ] Elderly men are at highest risk; however, melanoma is the most common cancer in young adults aged 25 to 29 years and the second most common cancer in those aged 15 to 29 years.[ ] Ocular melanoma is the most common cancer of the eye, with approximately

2018 PDQ - NCI's Comprehensive Cancer Database

17. Incidence of melanoma and outcomes of longitudinal melanonychia in a cohort of cases referred to a London dermatology department. (Abstract)

Incidence of melanoma and outcomes of longitudinal melanonychia in a cohort of cases referred to a London dermatology department. Longitudinal melanonychia is a pigmented longitudinal band on the nail plate and may occur due to melanocyte activation, nail matrix nevus, lentigo or subungual melanoma.1 In a racially diverse community, melanonychia is a relatively common presenting complaint. However, despite this, little is known about the incidence of melanoma in longitudinal melanonychia

2019 British Journal of Dermatology

18. The causes of nail apparatus pigmentation presenting to a melanoma screening clinic a prospective study. (Abstract)

The causes of nail apparatus pigmentation presenting to a melanoma screening clinic a prospective study. Advanced stage primary cutaneous malignant melanoma (PCMM) has a high mortality. PCMM may affect any area of the skin, including the nail apparatus (malignant melanoma or subungual melanoma). Although nail apparatus malignant melanoma (NAMM) is rare, delayed diagnosis carries a poor prognosis.The primary aim was to study the range of nail presentations and identify key patterns to aid (...) in differential diagnosis. A secondary aim was to quantify the number of patients requiring surgery, indications for biopsy, and the incidence and characteristics of NAMM.This was a prospective study of all referrals with nail apparatus pigmentation to a weekly dedicated melanoma screening clinic over a 6-month period.In total, 2246 patients were included. Of the 38 patients referred with nail pigmentation, 1 (2.6%) was diagnosed with NAMM and involved a fungating amelanotic lesion of the right hallux

2019 Clinical & Experimental Dermatology

19. Skin Cancer, Melanoma

Skin Cancer, Melanoma Melanoma Treatment (PDQ®)—Health Professional Version - National Cancer Institute Menu Search Search Search General Information About Melanoma Melanoma is a malignant tumor of melanocytes, which are the cells that make the pigment melanin and are derived from the neural crest. Although most melanomas arise in the skin, they may also arise from mucosal surfaces or at other sites to which neural crest cells migrate, including the uveal tract. Uveal melanomas differ (...) significantly from cutaneous melanoma in incidence, prognostic factors, molecular characteristics, and treatment. (Refer to the PDQ summary on for more information.) Incidence and Mortality Estimated new cases and deaths from melanoma in the United States in 2019:[ ] New cases: 96,480. Deaths: 7,230. Skin cancer is the most common malignancy diagnosed in the United States, with 5.4 million cancers diagnosed among 3.3 million people in 2012.[ ] Invasive melanoma represents about 1% of skin cancers

2012 PDQ - NCI's Comprehensive Cancer Database

20. Comparing SLNE With or Without Preoperative Hybrid SPECT/CT in Melanoma

information, Layout table for eligibility information Ages Eligible for Study: 18 Years to 75 Years (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Patients with malignant melanoma in AJCC stages Ib / II Tumor depth of ≥1.0 mm Age ≥18 years to ≤75 years Have a primary melanoma that is cutaneous (including head, neck, trunk, extremity, scalp, palm, sole, subungual skin tissues Eastern Cooperative Oncology Group (ECOG) performance status 0-1 (...) Signed written informed consent prior to the performance of any trial specific procedure Exclusion Criteria: History of previous or concurrent (i.e., second primary) invasive melanoma Primary melanoma of the eye, mucous membranes or internal viscera Any additional solid tumor or hematologic malignancy during the past 5 years except skin lesions of squamous cell carcinoma, basal cell carcinoma, or uterine cervical cancer Skin grafts, tissue transfers or flaps that have the potential to alter

2018 Clinical Trials

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>