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Sublingual Varices

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1. Sublingual Varices

Sublingual Varices Sublingual Varices Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Sublingual Varices Sublingual Varices Aka (...) : Sublingual Varices , Varicose Veins of Tongue , Caviar Lesions of Tongue From Related Chapters II. Epidemiology Develop with age : 10% of patients over age 40 years III. Signs Small purplish or blue round swellings under IV. Evaluation No significance Reassure patient Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Sublingual Varices." Click on the image (or right click) to open the source website in a new browser window. Related

2018 FP Notebook

2. Is there a connection between sublingual varices and hypertension? (PubMed)

Is there a connection between sublingual varices and hypertension? Sublingual varices have earlier been related to ageing, smoking and cardiovascular disease. The aim of this study was to investigate whether sublingual varices are related to presence of hypertension.In an observational clinical study among 431 dental patients tongue status and blood pressure were documented. Digital photographs of the lateral borders of the tongue for grading of sublingual varices were taken, and blood pressure (...) was graded as none/few (grade 0) or medium/severe (grade 1) presence of sublingual varices. Pearson's Chi-square test, Student's t-test, and multiple regression analysis were applied. Power calculation stipulated a study population of 323 patients.An association between sublingual varices and hypertension was found (OR = 2.25, p < 0.002). Mean systolic blood pressure was 123 and 132 mmHg in patients with grade 0 and grade 1 sublingual varices, respectively (p < 0.0001, CI 95 %). Mean diastolic blood

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2015 BMC Oral Health

3. Is there a connection between sublingual varices and hypertension? (PubMed)

Is there a connection between sublingual varices and hypertension? Sublingual varices have earlier been related to ageing, smoking and cardiovascular disease. The aim of this study was to investigate whether sublingual varices are related to presence of hypertension.In an observational clinical study among 431 dental patients tongue status and blood pressure were documented. Digital photographs of the lateral borders of the tongue for grading of sublingual varices were taken, and blood pressure (...) was graded as none/few (grade 0) or medium/severe (grade 1) presence of sublingual varices. Pearson's Chi-square test, Student's t-test, and multiple regression analysis were applied. Power calculation stipulated a study population of 323 patients.An association between sublingual varices and hypertension was found (OR = 2.25, p < 0.002). Mean systolic blood pressure was 123 and 132 mmHg in patients with grade 0 and grade 1 sublingual varices, respectively (p < 0.0001, CI 95 %). Mean diastolic blood

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2015 BMC oral health

4. Sublingual Varices

Sublingual Varices Sublingual Varices Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Sublingual Varices Sublingual Varices Aka (...) : Sublingual Varices , Varicose Veins of Tongue , Caviar Lesions of Tongue From Related Chapters II. Epidemiology Develop with age : 10% of patients over age 40 years III. Signs Small purplish or blue round swellings under IV. Evaluation No significance Reassure patient Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Sublingual Varices." Click on the image (or right click) to open the source website in a new browser window. Related

2015 FP Notebook

6. Royal Flying Doctor Service Western Operations Clinical manual part 1.Clinical guidelines

the referring practitioner is uncertain). ? Understand the plan for this patient and the rationale behind it. (Does this patient really need an urgent procedure or is the issue more one of convenience? Are they holding the catheter lab open for this patient, or not intending to do anything until tomorrow?). 2. Establish first line therapy for all ACS. ? Aspirin loading dose 300mg orally (Medical Chest Item 62). ? Glyceryl trinitrate (GTN) spray sublingual, titrated to pain and blood pressure (Medical Chest (...) location. 1. Diagnose and treat precipitating causes, including myocardial infarction, cardiac arrhythmias, pericardial effusion, hypertrophic cardiomyopathy and valvular heart disease. Consider non-cardiogenic pulmonary oedema. 2. Administer high flow oxygen with the patient sitting upright. Maximal supplemental oxygen followed by assisted ventilation should be used before resorting to a sea level cabin. 3. Give nitrates, either sublingually, or by infusion (commence at 10 ?g/min) (See Infusion

2014 Clinical Practice Guidelines Portal

7. Supportive care in multiple myeloma

disorder Platelet count <100 × 10 9 /l Acute stroke in previous month (haemorrhagic or ischaemic) Blood pressure >200 mmHg systolic or >120 mmHg diastolic Severe liver disease (abnormal PT or known varices) Severe renal disease (Creatinine clearance <30 ml/min) Undergoing procedure or intervention with high bleeding risk Other patients who are not receiving thalidomide or lenalidomide may also be at risk of VTE and thromboprophylaxis may be appropriate. This is particularly true of those admitted (...) (buccal, sublingual, nasal), TD, IV, Sp 12 μg/h TD patch over 72 h Reduced sedation, emesis, constipation cf morphine; Convenience of 3 d patch TM applications very short‐acting (1–2 h) – best reserved for incident (movement‐related) pains and dressing changes, etc.; Probably immunoneutral Safe in renal failure (Alternative for parenteral use is alfentanil) Safe Use rapid acting TM formulations with caution in patients with addictive tendencies; Affected by CYP3A4‐acting drugs Buprenorphine Partial

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2011 British Committee for Standards in Haematology

8. Inorganic Nitrite to Amplify the Benefits and Tolerability of Exercise Training in Heart Failure With Preserved Ejection Fraction (HFpEF) (INABLE-Training)

sublingual nitroglycerin (requirement for >1 sublingual nitroglycerin per week). No daily use of phosphodiesterase 5 (PDE5) inhibitors or soluble guanylyl cyclase activators and willing to withhold as needed use of PDE5 inhibitors for duration of study Ambulatory (not wheelchair / scooter dependent) Body size allows wearing of the accelerometer belt as confirmed by ability to comfortably fasten the test belt provided for the screening process. Willingness to wear the accelerometer belt for the duration (...) of the following: encephalopathy, variceal bleeding, International Normalized Ratio (INR) > 1.7 in the absence of anticoagulation treatment Terminal illness (other than HF) with expected survival of less than 1 year Enrollment or planned enrollment in another therapeutic clinical trial in next 3 months. Inability to comply with planned study procedures Pregnancy or breastfeeding mothers Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your

2016 Clinical Trials

9. Family Practice Notebook Updates 2016

encephalopathy Goal of <36 C (prevent fever) appears as effective as <33 C, with fewer adverse effects is contraindicated in including CNS and requiring s Sublingual tablets are now good for up to 2 years from manufacture date if kept at room with bottle capped Costs roughly $0.40/tablet, compared with >$1.50/spray or $7/ powder Medications is finally banned by AAP for under age 18 years old s Ask patients their preferred name, gender and pronoun (may differ from medical record) Preventive health screening (...) , reverse , empiric PPI IV and variceal management (gi, esophagus, procedure, er) temporizes in 60-90% until emergent endoscopy in exsanguinating Critical that gastric balloon is not inflated within esophagus (would result in ) (id, virus) Zika is an in the genus , which also includes and Transmitted by aedes which breed in water containers Mild symptoms (if any) include fever, maculopapular rash, , (as well as myalgias and ) Associated with and thousands of newborn cases in Brazil XI. Updates: March

2018 FP Notebook

10. Inorganic Nitrite Delivery to Improve Exercise Capacity in HFpEF

by answering # 2 to the following question: My ability to be active is most limited by: Joint, foot, leg, hip or back pain Shortness of breath and/or fatigue and/or chest pain Unsteadiness or dizziness Lifestyle, weather, or I just don't like to be active 6. Peak VO2 ≤75% predicted with peak respiratory exchange ratio≥1.0 CPET Normal Values for Peak VO2* Criteria (ml/kg/min) 7. No chronic nitrate therapy or not using intermittent sublingual nitroglycerin (requirement for >1 SL nitroglycerin per week (...) of the following: encephalopathy, variceal bleeding, INR > 1.7 in the absence of anticoagulation treatment Terminal illness (other than HF) with expected survival of less than 1 year Regularly (> 1x per week) swims or does water aerobics Enrollment or planned enrollment in another therapeutic clinical trial in next 3 months. Inability to comply with planned study procedures Pregnancy or breastfeeding mothers Contacts and Locations Go to Information from the National Library of Medicine To learn more about

2016 Clinical Trials

11. Family Practice Notebook Updates 2016

encephalopathy Goal of <36 C (prevent fever) appears as effective as <33 C, with fewer adverse effects is contraindicated in including CNS and requiring s Sublingual tablets are now good for up to 2 years from manufacture date if kept at room with bottle capped Costs roughly $0.40/tablet, compared with >$1.50/spray or $7/ powder Medications is finally banned by AAP for under age 18 years old s Ask patients their preferred name, gender and pronoun (may differ from medical record) Preventive health screening (...) , reverse , empiric PPI IV and variceal management (gi, esophagus, procedure, er) temporizes in 60-90% until emergent endoscopy in exsanguinating Critical that gastric balloon is not inflated within esophagus (would result in ) (id, virus) Zika is an in the genus , which also includes and Transmitted by aedes which breed in water containers Mild symptoms (if any) include fever, maculopapular rash, , (as well as myalgias and ) Associated with and thousands of newborn cases in Brazil XI. Updates: March

2017 FP Notebook

12. Endocrine and Nutritional Management of the Post-Bariatric Surgery Patient

RYGB ( , ). The initiation of vitamin B12 supplementation within 6 months postoperatively is recommended by most surgical groups in the absence of controlled studies. Oral crystalline vitamin B12 at a dose of at least 350 μg/d has been shown to maintain normal plasma vitamin B12 levels ( – ). Optimal dosing of oral, sublingual, or intranasal forms of B12 supplementation has not been well studied. However, in a study of postoperative RYGB patients by Clements et al. ( ), 1000 μg vitamin B12 im every (...) 3 months or intranasal B12, 1000 μg every week, resulted in a lower incidence of vitamin B12 deficiency (3.6% at 1 yr and 2.3% at 2 yr) compared with the frequency of 12–37% described by Brolin and Leung ( ). In many institutions, intranasal administration of vitamin B12 has been supplanted by sublingual administration of vitamin B12. One study demonstrated that oral and sublingual administration of 500 μg vitamin B12 were equally efficacious in correcting vitamin B12 deficiency ( ). Regardless

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2010 The Endocrine Society

13. Pharmacokinetics and Safety of ALKS 5461 in Healthy Subjects and Subjects With Hepatic Impairment and Normal Hepatic Function

: Interventional (Clinical Trial) Actual Enrollment : 40 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: A Phase 1 Study of the Pharmacokinetics, Safety, and Tolerability of ALKS 5461 in Subjects With Hepatic Impairment Study Start Date : May 2015 Actual Primary Completion Date : December 2015 Actual Study Completion Date : December 2015 Arms and Interventions Go to Arm Intervention/treatment Experimental: ALKS 5461 Sublingual (...) obstruction, severe ascites, severe portal hypertension, surgical systemic shunts, or other clinically relevant liver-related disorder or condition Has received a liver transplant Has had esophageal variceal bleeding in the past 2 months Additional criteria may apply Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer

2015 Clinical Trials

14. Nitrate's Effect on Activity Tolerance in Heart Failure With Preserved Ejection Fraction

≥ 0.43 (♂ or ♀) [(IVS+PW)/LVEDD] Posterior wall thickness ≥ 0.9 (♀) or 1.0 (♂) cm No chronic nitrate therapy or infrequent (≤ 1x week) use of intermittent sublingual nitroglycerin within last 3 months Ambulatory (not wheelchair / scooter / walker / cane dependent) HF is the primary factor limiting activity as indicated by answering # 2 to the following question: My ability to be active is most limited by: Joint, foot, leg, hip or back pain Shortness of breath and/or fatigue and/or chest pain (...) pacing within past 3 months Primary hypertrophic cardiomyopathy Infiltrative cardiomyopathy (amyloid) Constrictive pericarditis or tamponade Active myocarditis Complex congenital heart disease Active collagen vascular disease More than mild aortic or mitral stenosis Intrinsic (prolapse, rheumatic) valve disease with moderate to severe or severe mitral, tricuspid or aortic regurgitation Acute or chronic severe liver disease as evidenced by any of the following: encephalopathy, variceal bleeding, INR

2014 Clinical Trials

15. Oral Manifestations of Systemic Diseases (Treatment)

, alcoholic liver disease, and nonalcoholic fatty liver disease, although countless other conditions can cause CLD. [ ] CLD is a leading cause of mortality and morbidity both in the United States and around the world. [ ] The systemic manifestations of CLD are numerous and beyond the scope of this article. They can be classified as those due to synthetic dysfunction (eg, coagulopathies, hypoalbuminemia), portal hypertension (eg, ascites, esophageal varices, hemorrhoids), bilirubin secretion (eg, jaundice (...) to coagulopathies, patients may have petechiae on the mucous membranes or excessive gingival bleeding with minor trauma, often in the absence of inflammation. [ ] Therefore, special care must be taken during any type of surgery, oral or otherwise, as the patient is at high risk for severe hemorrhage. Jaundice may also appear in the oral mucosa due to the yellow pigmentation that results from deposition of bilirubin into the submucosa. [ ] Of note, because the sublingual and soft palate mucosae are very thin

2014 eMedicine.com

16. Oral Manifestations of Systemic Diseases (Overview)

, alcoholic liver disease, and nonalcoholic fatty liver disease, although countless other conditions can cause CLD. [ ] CLD is a leading cause of mortality and morbidity both in the United States and around the world. [ ] The systemic manifestations of CLD are numerous and beyond the scope of this article. They can be classified as those due to synthetic dysfunction (eg, coagulopathies, hypoalbuminemia), portal hypertension (eg, ascites, esophageal varices, hemorrhoids), bilirubin secretion (eg, jaundice (...) to coagulopathies, patients may have petechiae on the mucous membranes or excessive gingival bleeding with minor trauma, often in the absence of inflammation. [ ] Therefore, special care must be taken during any type of surgery, oral or otherwise, as the patient is at high risk for severe hemorrhage. Jaundice may also appear in the oral mucosa due to the yellow pigmentation that results from deposition of bilirubin into the submucosa. [ ] Of note, because the sublingual and soft palate mucosae are very thin

2014 eMedicine.com

17. Oral Manifestations of Systemic Diseases (Follow-up)

, alcoholic liver disease, and nonalcoholic fatty liver disease, although countless other conditions can cause CLD. [ ] CLD is a leading cause of mortality and morbidity both in the United States and around the world. [ ] The systemic manifestations of CLD are numerous and beyond the scope of this article. They can be classified as those due to synthetic dysfunction (eg, coagulopathies, hypoalbuminemia), portal hypertension (eg, ascites, esophageal varices, hemorrhoids), bilirubin secretion (eg, jaundice (...) to coagulopathies, patients may have petechiae on the mucous membranes or excessive gingival bleeding with minor trauma, often in the absence of inflammation. [ ] Therefore, special care must be taken during any type of surgery, oral or otherwise, as the patient is at high risk for severe hemorrhage. Jaundice may also appear in the oral mucosa due to the yellow pigmentation that results from deposition of bilirubin into the submucosa. [ ] Of note, because the sublingual and soft palate mucosae are very thin

2014 eMedicine.com

18. Oral Manifestations of Systemic Diseases (Diagnosis)

, alcoholic liver disease, and nonalcoholic fatty liver disease, although countless other conditions can cause CLD. [ ] CLD is a leading cause of mortality and morbidity both in the United States and around the world. [ ] The systemic manifestations of CLD are numerous and beyond the scope of this article. They can be classified as those due to synthetic dysfunction (eg, coagulopathies, hypoalbuminemia), portal hypertension (eg, ascites, esophageal varices, hemorrhoids), bilirubin secretion (eg, jaundice (...) to coagulopathies, patients may have petechiae on the mucous membranes or excessive gingival bleeding with minor trauma, often in the absence of inflammation. [ ] Therefore, special care must be taken during any type of surgery, oral or otherwise, as the patient is at high risk for severe hemorrhage. Jaundice may also appear in the oral mucosa due to the yellow pigmentation that results from deposition of bilirubin into the submucosa. [ ] Of note, because the sublingual and soft palate mucosae are very thin

2014 eMedicine.com

19. Critical care - Shock

ulcer, esophageal varices, or ruptured aortic aneurysm. Bleeding may be overt (eg, hematemesis, melena) or concealed (eg, ruptured ectopic pregnancy). Hypovolemic shock may also follow increased losses of body fluids other than blood (see Table: ). Table Hypovolemic Shock Caused by Body Fluid Loss Site of Fluid Loss Mechanism of Loss Skin Thermal or chemical burn, sweating due to excessive heat exposure GI tract Vomiting, diarrhea Kidneys Diabetes mellitus or insipidus, adrenal insufficiency, salt (...) for diagnosis and initial management of patients with shock of uncertain or mixed etiology or with severe shock, especially when accompanied by oliguria or pulmonary edema. Echocardiography (bedside or transesophageal) is a less invasive alternative. Serial measurements of ABGs, Hct, electrolytes, serum creatinine, and blood lactate are obtained. Sublingual CO 2 measurement (see ), if available, is a noninvasive monitor of visceral perfusion. A well-designed flow sheet is helpful. Because tissue

2013 Merck Manual (19th Edition)

20. Aliskiren HCTZ Compared to Amlodipine in Patients With Stage 2 Systolic Hypertension and Diabetes Mellitus

pharmacological therapy (except sublingual nitroglycerin). Second or third degree heart block without a pacemaker. Atrial fibrillation or atrial flutter at Visit 1, or potentially life-threatening or any symptomatic arrhythmia during the 12 months prior to Visit 1. Clinically significant valvular heart disease. History of angioedema during use of an ACE inhibitor. History or evidence of drug or alcohol abuse within the last 12 months. Any surgical or medical condition, which in the opinion of the investigator (...) of hepatic encephalopathy, a history of esophageal varices, or a history of portocaval shunt. Evidence of renal impairment as determined by any one of the following: serum creatinine > 1.5 x ULN at Visit 1, a history of dialysis, or a history of nephrotic syndrome. Current treatment with cholestyramine or colestipol resins History of noncompliance to medical regimes or unwillingness to comply with the study protocol. Any condition that in the opinion of the investigator would confound the evaluation

2008 Clinical Trials

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