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Subcutaneous Fat Necrosis

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1. Subcutaneous Fat Necrosis and Hypercalcemia After Therapeutic Hypothermia in Patients With Hypoxic-ischemic Encephalopathy: A Case Series Full Text available with Trip Pro

Subcutaneous Fat Necrosis and Hypercalcemia After Therapeutic Hypothermia in Patients With Hypoxic-ischemic Encephalopathy: A Case Series Therapeutic hypothermia (TH) is provided to newborns with moderate to severe hypoxic-ischemic encephalopathy (HIE) to improve survival and long-term neurodevelopmental outcomes. Although the benefits certainly outweigh the risks associated with therapeutic hypothermia, it is important to be mindful of potential rare side effects in the background of asphyxia (...) -related injury to various body organs. One of those side effects includes subcutaneous fat necrosis (SCFN) that can occur in term newborns after perinatal hypoxia-ischemia or other stressing factors such as systemic hypothermia. It is usually a self-limited condition, however, in some cases, it can lead to severe hypercalcemia. We report three such cases of SCFN in newborns with HIE treated with TH. Due to potential long-term complications, such as metastatic calcifications, caregivers should

2018 Cureus

2. Neonatal subcutaneous fat necrosis with hypercalcemia treatment using calcitonin Full Text available with Trip Pro

Neonatal subcutaneous fat necrosis with hypercalcemia treatment using calcitonin Subcutaneous fat necrosis of newborn is a form of noninfectious panniculitis. It is an uncommon condition and mostly occurs in full-term infants within first weeks of life that have had a significant condition such as hypoxic-ischemic encephalopathy at the time of birth. Subcutaneous fat necrosis of newborn is usually a self-limiting condition but may be associated with hypercalcemia, which may lead to life (...) threatening levels. Hypercalcemia is a significant reason of subcutaneous fat necrosis and needs an intervention involving hyperhydration, calcitonin, diuretics, steroids and sometimes bisphosphonate in resistant cases. Here, we have reported the case of a term infant who developed extensive subcutaneous fat necrosis in the first week of life after significant perinatal hypoxic injury. Her condition was complicated by hypercalcemia resistant to prolonged medical treatment with hyperhydration, diuretic

2018 Saudi medical journal

3. Zoledronic acid for neonatal subcutaneous fat necrosis Full Text available with Trip Pro

Zoledronic acid for neonatal subcutaneous fat necrosis Subcutaneous fat necrosis (SFN) in infants producing severe hypercalcemia is a life-threatening emergency. Pathophysiology may include enhanced gastrointestinal calcium absorption and bone resorption. We treated an infant with SFN and serum calcium of 15 mg/dL with prednisolone and low-dose zoledronic acid. Serum calcium promptly normalized without rebound hypocalcemia, and redosing of zoledronic acid was not necessary.

2017 Clinical Case Reports

4. Hypocalcemia Associated with Subcutaneous Fat Necrosis of the Newborn: Case Report and Literature Review Full Text available with Trip Pro

Hypocalcemia Associated with Subcutaneous Fat Necrosis of the Newborn: Case Report and Literature Review Subcutaneous fat necrosis of the newborn (SCFNN) is a rare benign inflammatory disorder of the adipose tissue but may be complicated by hypercalcemia or less frequently, hypocalcemia, resulting in morbidity and mortality. Here we report the case of a neonate with subcutaneous fat necrosis who surprisingly developed hypocalcemia instead of hypercalcemia. A full-term female neonate

2017 Oman medical journal

5. Subcutaneous Fat Necrosis

Subcutaneous Fat Necrosis Subcutaneous Fat Necrosis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Subcutaneous Fat Necrosis (...) Subcutaneous Fat Necrosis Aka: Subcutaneous Fat Necrosis II. Epidemiology May appear up to 1 month of age III. Signs Erythematous s or s IV. Distribution Cheeks or buttocks V. Associations Rarely associated with VI. Course Most lesions resolve spontaneously VII. Management Fluctuant lesions may be aspirated Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Subcutaneous Fat Necrosis." Click on the image (or right click) to open the source

2018 FP Notebook

6. Neutrophil-rich subcutaneous fat necrosis of the newborn: A potential mimic of infection. (Abstract)

Neutrophil-rich subcutaneous fat necrosis of the newborn: A potential mimic of infection. The inflammatory infiltrate seen in biopsy specimens obtained from patients with subcutaneous fat necrosis of the newborn (SCFN) has classically been described as consisting mostly of histiocytes. However, we encountered patients with SCFN whose biopsy specimens revealed mostly neutrophils, prompting infection to be an initial consideration.We sought to describe cases of SCFN in which neutrophils formed

2016 Journal of American Academy of Dermatology

7. Subcutaneous fat necrosis in neonates after therapeutic hypothermia – report of two cases Full Text available with Trip Pro

Subcutaneous fat necrosis in neonates after therapeutic hypothermia – report of two cases 27279827 2016 06 09 2018 11 13 1642-395X 33 2 2016 Apr Postepy dermatologii i alergologii Postepy Dermatol Alergol Subcutaneous fat necrosis in neonates after therapeutic hypothermia - report of two cases. 152-4 10.5114/ada.2016.59164 Szpecht Dawid D Department of Neonatology, Poznan University of Medical Sciences, Poznan, Poland. Bagnosz-Magnuszewska Alina A Department of Neonatology, Poznan University

2016 Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii

8. Subcutaneous encapsulated fat necrosis Full Text available with Trip Pro

Subcutaneous encapsulated fat necrosis We have described subcutaneous encapsulated fat necrosis, which is benign, usually asymptomatic and underreported. Images have only been published on two earlier occasions, in which the necrotic nodules appear "pearly" than the cloudy yellow surface in present case. The presented image may help future surgeons to establish the diagnosis peroperatively.

2016 Clinical Case Reports

9. Breast panniculitis with liquefactive fat necrosis: A case report Full Text available with Trip Pro

Breast panniculitis with liquefactive fat necrosis: A case report Panniculitis is a group of heterogeneous disorders characterized by inflammation of the subcutaneous adipose tissue. Panniculitis of breast tissue as the initial manifestation has rarely been reported and is often misdiagnosed. Breast panniculitis may cause substantial morbidity and early diagnosis and treatment are important for the prognosis of the disease. The present study has reported a case of panniculitis with inflammation

2018 Experimental and therapeutic medicine

10. Subcutaneous fat necrosis in neonates with hypoxic ischaemic encephalopathy registered in the Swiss National Asphyxia and Cooling Register Full Text available with Trip Pro

Subcutaneous fat necrosis in neonates with hypoxic ischaemic encephalopathy registered in the Swiss National Asphyxia and Cooling Register Neonates with hypoxic ischaemic encephalopathy (HIE) are routinely treated with therapeutic hypothermia (TH) for 72 h in order to improve neurological outcome. Subcutaneous fat necrosis (SCFN) is an adverse event occurring in neonates with HIE.We analyzed risk factors for SCFN regarding demographic factors, cooling methods and deviation from target (...) % in neonates without SCFN. Neonates with SCFN showed 3.6% of all measured temperatures below target temperature range compared to 12.7% in neonates without SCFN.Subcutaneous fat necrosis in the neonate with HIE undergoing TH is a potential adverse event that seems to occur independently from the whole-body cooling method applied and proportion of temperature measurements outside target temperature range. In this cohort, moderate overcooling associated with moderate hypothermia (33.0-34.0 °C) does not seem

2015 BMC pediatrics

11. Timing of Operative Debridement for Necrotizing Soft Tissue

. Address for reprints: Rondi B. Gelbard, MD, Emory University School of Medicine, 69 Jesse Hill Jr. Drive, SE, Glenn Memorial Building, Room 315, Atlanta, Georgia 30303; email: . Abstract BACKGROUND Necrotizing soft tissue infections (NSTI) are rare, life-threatening, soft-tissue infections characterized by rapidly spreading inflammation and necrosis of the skin, subcutaneous fat, and fascia. While it is widely accepted that delay in surgical debridement contributes to increased mortality (...) . Necrotizing fasciitis: strategies for diagnosis and management. World J Emerg Surg . 2007;2:19. Holtom PD. Necrotizing soft tissue infections. West J Med . 1995;163(6):568–569. Meade JW, Mueller CB. Necrotizing infections of subcutaneous tissue and fascia. Ann Surg . 1968;168(2):274–280. Patino J, Castro D. Necrotizing lesions of soft tissues: a review. World J Surg . 1991;15:235–239. Wall DB, Klein SR, Black S, de Virgilio C. A simple model to help distinguish necrotizing fasciitis from nonnecrotizing

2018 Eastern Association for the Surgery of Trauma

12. Neonatal Hypercalcemia Secondary to Subcutaneous Fat Necrosis Successfully Treated with Pamidronate: A Case Series and Literature Review Full Text available with Trip Pro

Neonatal Hypercalcemia Secondary to Subcutaneous Fat Necrosis Successfully Treated with Pamidronate: A Case Series and Literature Review Subcutaneous fat necrosis (SCFN) is a noninfectious panniculitis that occurs in term infants who experience significant distress in the 1st weeks of life, including hypoxic ischemic encephalopathy (HIE). Since the introduction of therapeutic hypothermia for HIE, there have been a few published case reports of SCFN, following this modality of treatment

2014 AJP Reports

13. Severe hypercalcaemia due to subcutaneous fat necrosis: presentation, management and complications. Full Text available with Trip Pro

Severe hypercalcaemia due to subcutaneous fat necrosis: presentation, management and complications. Subcutaneous fat necrosis (SCFN) is a rare form of panniculitis in infants that generally occurs following birth trauma, meconium aspiration, or therapeutic cooling. Severe hypercalcaemia occurs in a subset of patients, but data on its presentation, management and outcomes are limited. This report details the clinical course and complications of infants treated for severe hypercalcaemia (peak

2014 Archives of Disease in Childhood. Fetal and Neonatal Edition

14. Subcutaneous Fat Necrosis of the Newborn (Overview)

in subcutaneous fat necrosis of the newborn. [ ] and may contribute to hypercalcemia through a different pathway. Alternative explanations for hypercalcemia include the release of calcium from necrotic fat cells or elevated parathyroid hormone (PTH) levels that indirectly increase serum calcium by promoting osteoclast activity. [ ] A child with cyanotic heart disease treated with prostaglandins (intravenous PGE1) to maintain patent ductus arteriosus developed subcutaneous fat necrosis of the newborn; when (...) Subcutaneous Fat Necrosis of the Newborn (Overview) Subcutaneous Fat Necrosis of the Newborn: Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA4MTkxMC1vdmVydmlldw

2014 eMedicine.com

15. Subcutaneous Fat Necrosis of the Newborn (Diagnosis)

in subcutaneous fat necrosis of the newborn. [ ] and may contribute to hypercalcemia through a different pathway. Alternative explanations for hypercalcemia include the release of calcium from necrotic fat cells or elevated parathyroid hormone (PTH) levels that indirectly increase serum calcium by promoting osteoclast activity. [ ] A child with cyanotic heart disease treated with prostaglandins (intravenous PGE1) to maintain patent ductus arteriosus developed subcutaneous fat necrosis of the newborn; when (...) Subcutaneous Fat Necrosis of the Newborn (Diagnosis) Subcutaneous Fat Necrosis of the Newborn: Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA4MTkxMC1vdmVydmlldw

2014 eMedicine.com

16. Subcutaneous Fat Necrosis of the Newborn (Follow-up)

Subcutaneous Fat Necrosis of the Newborn (Follow-up) Subcutaneous Fat Necrosis of the Newborn Treatment & Management: Medical Care, Surgical Care, Consultations Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA4MTkxMC10cmVhdG1lbnQ= processing > Subcutaneous Fat Necrosis of the Newborn Treatment & Management Updated: May 15, 2018 Author: Sungat K Grewal; Chief Editor: William D James, MD Share Email Print Feedback Close Sections Sections Subcutaneous Fat Necrosis of the Newborn Treatment Medical Care Subcutaneous fat necrosis of the newborn (SFNN) is usually a self-limited process that does not require treatment. Interventions have focused on the prevention of subcutaneous fat necrosis of the newborn in the setting

2014 eMedicine.com

17. Subcutaneous Fat Necrosis of the Newborn (Treatment)

Subcutaneous Fat Necrosis of the Newborn (Treatment) Subcutaneous Fat Necrosis of the Newborn Treatment & Management: Medical Care, Surgical Care, Consultations Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA4MTkxMC10cmVhdG1lbnQ= processing > Subcutaneous Fat Necrosis of the Newborn Treatment & Management Updated: May 15, 2018 Author: Sungat K Grewal; Chief Editor: William D James, MD Share Email Print Feedback Close Sections Sections Subcutaneous Fat Necrosis of the Newborn Treatment Medical Care Subcutaneous fat necrosis of the newborn (SFNN) is usually a self-limited process that does not require treatment. Interventions have focused on the prevention of subcutaneous fat necrosis of the newborn in the setting

2014 eMedicine.com

18. Surgical management of subcutaneous fat necrosis of the newborn required due to a lack of improvement: a very rare case. (Abstract)

Surgical management of subcutaneous fat necrosis of the newborn required due to a lack of improvement: a very rare case. Subcutaneous fat necrosis of the newborn (ScFN) is an uncommon and transient disease characterized by defined areas of fat necrosis and overlying cutaneous nodule lesions. It usually becomes apparent within the first 6 weeks of life in full-term or post-term infants. It is caused by generalized and/or local tissue hypoperfusion. The skin lesions of ScFN tend generally (...) to improve spontaneously in a few weeks. We present a full-term newborn with birth distress. After therapeutic hypothermia, she presented voluminous and numerous subcutaneous fat necrosis with extensive calcifications. Surgical management was decided at her ninth month because of a total lack of regression. Hypercalcaemia, the most threatening complication, appeared only after this delayed surgery.© 2013 British Association of Dermatologists.

2013 British Journal of Dermatology

19. Subcutaneous Fat Necrosis

Subcutaneous Fat Necrosis Subcutaneous Fat Necrosis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Subcutaneous Fat Necrosis (...) Subcutaneous Fat Necrosis Aka: Subcutaneous Fat Necrosis II. Epidemiology May appear up to 1 month of age III. Signs Erythematous s or s IV. Distribution Cheeks or buttocks V. Associations Rarely associated with VI. Course Most lesions resolve spontaneously VII. Management Fluctuant lesions may be aspirated Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Subcutaneous Fat Necrosis." Click on the image (or right click) to open the source

2015 FP Notebook

20. Review of the Mechanisms and Effects of Noninvasive Body Contouring Devices on Cellulite and Subcutaneous Fat Full Text available with Trip Pro

Review of the Mechanisms and Effects of Noninvasive Body Contouring Devices on Cellulite and Subcutaneous Fat Today, different kinds of non-invasive body contouring modalities, including cryolipolysis, radiofrequency (RF), low-level laser therapy (LLLT), and high-intensity focused ultrasound (HIFU) are available for reducing the volume of subcutaneous adipose tissue or cellulite. Each procedure has distinct mechanisms for stimulating apoptosis or necrosis adipose tissue. In addition (...) to the mentioned techniques, some investigations are underway for analyzing the efficacy of other techniques such as whole body vibration (WBV) and extracorporeal shockwave therapy (ESWT). In the present review the mechanisms, effects and side effects of the mentioned methods have been discussed. The effect of these devices on cellulite or subcutaneous fat reduction has been assessed.We searched pubmed, google scholar and the cochrane databases for systemic reviews, review articles, meta-analysis

2016 International journal of endocrinology and metabolism

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