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Subacute Granulomatous Thyroiditis

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1. Subacute granulomatous thyroiditis

Subacute granulomatous thyroiditis Subacute granulomatous thyroiditis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Subacute granulomatous thyroiditis Last reviewed: February 2019 Last updated: March 2018 Summary Inflammation of the thyroid characterised by a triphasic course of transient thyrotoxicosis, followed by hypothyroidism, followed by a return to euthyroidism. The thyrotoxic phase is due to thyroid (...) therapy is generally necessary. Non-steroidal anti-inflammatory drugs and beta-blockers may be used for symptoms. Some patients with severe symptoms may also require corticosteroids, opioid analgesics, or potassium iodide or iopanoic acid to reduce the conversion of T4 to the more biologically active form of thyroid hormone, T3. Definition Subacute granulomatous thyroiditis is a self-limited inflammation of the thyroid gland. It is associated with a triphasic clinical course that lasts for a few weeks

2018 BMJ Best Practice

2. Fine-Needle Aspiration of De Quervain’s Thyroiditis (Subacute Granulomatous Thyroiditis): A Cytological Review of 20 Cases Full Text available with Trip Pro

Fine-Needle Aspiration of De Quervain’s Thyroiditis (Subacute Granulomatous Thyroiditis): A Cytological Review of 20 Cases De Quervain's Thyroiditis (DQT) is a self limiting inflammatory disease of the thyroid gland that presents with pain and sore throat. Although the diagnosis is usually made clinically, Fine Needle Aspiration (FNA) may provide assistance, particularly in excluding other thyroid lesions.The objective of this study was to reveal the cytological characteristics of DQT.We (...) followed by epithelioid cell clusters in 15 and colloid in 13 cases.Presence of follicular epithelial cells, large MNGCs and dirty background of cellular debris, mixed inflammatory cells with predominance of lymphocytes and macrophages were the most striking and consistent features for diagnosis of DQT in cytological smears. The above findings in consideration with the clinical history will help us to reach a definitive diagnosis. FNA also proves to be a useful tool in excluding other thyroid lesions

2017 Journal of clinical and diagnostic research : JCDR

3. Subacute Granulomatous Thyroiditis

Subacute Granulomatous Thyroiditis Subacute Granulomatous Thyroiditis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Subacute (...) Granulomatous Thyroiditis Subacute Granulomatous Thyroiditis Aka: Subacute Granulomatous Thyroiditis , Granulomatous Thyroiditis , Giant Cell Thyroiditis , Subacute Thyroiditis , de Quervain's Thyroiditis , de Quervain Thyroiditis II. Definition associated with Viral Infection III. Epidemiology : 5 per 100,000 persons Most common cause of Peak between ages 40 to 50 years More common in women by 4 fold Peak onset in late summer and early fall months IV. Pathophysiology Associated with HLA-B35 associated

2018 FP Notebook

4. Subacute granulomatous (De Quervain's) thyroiditis: Fine-needle aspiration cytology and ultrasonographic characteristics of 21 cases Full Text available with Trip Pro

Subacute granulomatous (De Quervain's) thyroiditis: Fine-needle aspiration cytology and ultrasonographic characteristics of 21 cases Subacute granulomatous thyroiditis (SGT) is an inflammatory disease that presents with different clinical and cytological characteristics. Although the diagnosis is generally made clinically, imaging methods and fine-needle aspiration (FNA) may provide assistance, particularly in atypical cases. The objective of this study is to reveal the ultrasonographic (USG (...) , the multinuclear giant cells (MNGCs) found in all cases were accompanied by a dirty background containing varying numbers of granulomatous structures, including isolated epithelioid histiocytes, proliferated/regenerated follicle epithelium cells and inflammatory cells and colloid.Though hypoechoic and heterogeneous areas with irregular margins are strongly associated with thyroiditis, SGT may also appear as painful or painless hypoechoic, solid nodules and generate challenges in differential diagnosis

2015 CytoJournal

5. Subacute (granulomatous) thyroiditis associated with granulomatous changes in adjacent lymph nodes. Full Text available with Trip Pro

Subacute (granulomatous) thyroiditis associated with granulomatous changes in adjacent lymph nodes. 5765406 1969 04 04 2018 11 13 0008-4409 100 8 1969 Feb 22 Canadian Medical Association journal Can Med Assoc J Subacute (granulomatous) thyroiditis associated with granulomatous changes in adjacent lymph nodes. 388-90 Danyluk J M JM Stirrat J H JH Laskin M M MM eng Journal Article Canada Can Med Assoc J 0414110 0008-4409 AIM IM Adult Female Granuloma Humans Lymph Nodes pathology Thyroiditis

1969 Canadian Medical Association Journal

6. Assessment of thyroid mass

observing known microcarcinomas is to use restraint in biopsying lesions less than 1 cm in diameter. Differentials Colloid nodule Thyroid adenoma or hyperplastic nodule, single (solid or complex) Non-toxic multinodular goitre Differentiated thyroid cancer (papillary, follicular) Toxic adenoma, single Toxic multinodular goitre Medullary thyroid cancer Anaplastic thyroid cancer Lymphoma Simple epithelial-lined thyroid cyst Thyroglossal duct cyst Acute suppurative thyroiditis Subacute granulomatous (...) Assessment of thyroid mass Assessment of thyroid mass - Differential diagnosis of symptoms | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Assessment of thyroid mass Last reviewed: February 2019 Last updated: January 2019 Summary Thyroid parenchymal expansion can result from diffuse enlargement or infiltration of the thyroid gland or from the presence of one or more thyroid nodules. A thyroid nodule is a discrete lesion distinct from the surrounding

2019 BMJ Best Practice

7. Subacute Granulomatous Thyroiditis

Subacute Granulomatous Thyroiditis Subacute Granulomatous Thyroiditis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Subacute (...) Granulomatous Thyroiditis Subacute Granulomatous Thyroiditis Aka: Subacute Granulomatous Thyroiditis , Granulomatous Thyroiditis , Giant Cell Thyroiditis , Subacute Thyroiditis , de Quervain's Thyroiditis , de Quervain Thyroiditis II. Definition associated with Viral Infection III. Epidemiology : 5 per 100,000 persons Most common cause of Peak between ages 40 to 50 years More common in women by 4 fold Peak onset in late summer and early fall months IV. Pathophysiology Associated with HLA-B35 associated

2015 FP Notebook

8. Assessment of thyroid mass

observing known microcarcinomas is to use restraint in biopsying lesions less than 1 cm in diameter. Differentials Colloid nodule Thyroid adenoma or hyperplastic nodule, single (solid or complex) Non-toxic multinodular goitre Differentiated thyroid cancer (papillary, follicular) Toxic adenoma, single Toxic multinodular goitre Medullary thyroid cancer Anaplastic thyroid cancer Lymphoma Simple epithelial-lined thyroid cyst Thyroglossal duct cyst Acute suppurative thyroiditis Subacute granulomatous (...) Assessment of thyroid mass Assessment of thyroid mass - Differential diagnosis of symptoms | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Assessment of thyroid mass Last reviewed: February 2019 Last updated: January 2019 Summary Thyroid parenchymal expansion can result from diffuse enlargement or infiltration of the thyroid gland or from the presence of one or more thyroid nodules. A thyroid nodule is a discrete lesion distinct from the surrounding

2018 BMJ Best Practice

9. Painless lymphocytic thyroiditis

://www.ncbi.nlm.nih.gov/pubmed/20144025?tool=bestpractice.com subacute (granulomatous, de Quervain), Fatourechi V, Aniszewski JP, Fatourechi GZ, et al. Clinical features and outcome of subacute thyroiditis in an incident cohort: Olmstead County, Minnesota, study. J Clin Endocrinol Metab. 2003 May;88(5):2100-5. http://press.endocrine.org/doi/full/10.1210/jc.2002-021799 http://www.ncbi.nlm.nih.gov/pubmed/12727961?tool=bestpractice.com palpation, Stang MT, Yim JH, Challinor SM, et al. Hyperthyroidism after parathyroid (...) -mediated lymphocytic inflammation of the thyroid gland resulting in a destructive thyroiditis with release of thyroid hormone and transient thyrotoxicosis (hyperthyroidism). Woolf PD. Transient painless thyroiditis with hyperthyroidism: a variant of lymphocytic thyroiditis? Endocr Rev. 1980 Fall;1(4):411-20. http://www.ncbi.nlm.nih.gov/pubmed/7018893?tool=bestpractice.com Samuels MH. Subacute, silent and postpartum thyroiditis. Med Clin North Am. 2012 Mar;96(2):223-33. http://www.ncbi.nlm.nih.gov

2018 BMJ Best Practice

10. Subacute Granulomatous Thyroiditis: A Clinicopathologic Review Full Text available with Trip Pro

Subacute Granulomatous Thyroiditis: A Clinicopathologic Review 17859644 2007 09 17 2018 11 13 0003-4932 153 1 1961 Jan Annals of surgery Ann. Surg. Subacute Granulomatous Thyroiditis: A Clinicopathologic Review. 149-56 Stein A A AA Hernandez I I McClintock J C JC eng Journal Article United States Ann Surg 0372354 0003-4932 1961 1 1 0 0 1961 1 1 0 1 1961 1 1 0 0 ppublish 17859644 PMC1613799 Surg Gynecol Obstet. 1954 Feb;98(2):197-212 13135910 J Clin Endocrinol Metab. 1956 Jul;16(7):848-68

1961 Annals of Surgery

11. De Quervain's subacute granulomatous thyroiditis: histological identification and incidence Full Text available with Trip Pro

De Quervain's subacute granulomatous thyroiditis: histological identification and incidence The histological features of de Quervain's subacute granulomatous thyroiditis are described, on the basis of a study of six specimens. This condition, unlike Hashimoto's disease, rarely causes permanent hypothyroidism; its histological identification is thus of practical importance. Areas of thyroid affected by the disease show intrafollicular cellular infiltration, with partial or complete loss (...) a striking appearance, aiding recognition of the disease. Some follicles contain numerous giant cells, often grouped around a central pool of residual colloid; others may contain a considerable proportion of neutrophil polymorphs or show radially aligned spindle-shaped cells.A study has also been made of the incidence of de Quervain's thyroiditis in surgical material in Sheffield during the seven year period 1955-61. Only two examples were found in a total of 1,282 cases of primary thyroid disease

1963 Journal of Clinical Pathology

12. Guidance on the reporting of thyroid cytology specimens

Guidance on the reporting of thyroid cytology specimens CEff 200116 1 V5 Final Guidance on the reporting of thyroid cytology specimens January 2016 Authors: Dr Paul Cross, Gateshead Health NHS Foundation Trust (Chair) Dr Ashish Chandra, Guys and St Thomas’s NHS Foundation Trust Dr Thomas Giles, Royal Liverpool and Broadgreen University Hospitals NHS Trust Dr Sarah Johnson, Newcastle upon Tyne Hospitals NHS Foundation Trust Dr Gabrijela Kocjan, University College London Hospitals NHS Foundation (...) Trust Dr David Poller, Portsmouth Hospitals NHS Trust Professor Tim Stephenson, Sheffield Teaching Hospitals NHS Foundation Trust Unique document number G089 Document name Guidance on the reporting of thyroid cytology specimens Version number 2 Produced by Dr P Cross (Chair), Dr A Chandra, Dr T Giles, Dr S Johnson, Dr G Kocjan, Dr D Poller and Professor T Stephenson. The authors are all consultant cellular pathologists, reporting thyroid histology and/or cytology, some of whom hold or have held

2016 Royal College of Pathologists

13. Guidance on the reporting of thyroid cytology specimens

Guidance on the reporting of thyroid cytology specimens CEff 200116 1 V5 Final Guidance on the reporting of thyroid cytology specimens January 2016 Authors: Dr Paul Cross, Gateshead Health NHS Foundation Trust (Chair) Dr Ashish Chandra, Guys and St Thomas’s NHS Foundation Trust Dr Thomas Giles, Royal Liverpool and Broadgreen University Hospitals NHS Trust Dr Sarah Johnson, Newcastle upon Tyne Hospitals NHS Foundation Trust Dr Gabrijela Kocjan, University College London Hospitals NHS Foundation (...) Trust Dr David Poller, Portsmouth Hospitals NHS Trust Professor Tim Stephenson, Sheffield Teaching Hospitals NHS Foundation Trust Unique document number G089 Document name Guidance on the reporting of thyroid cytology specimens Version number 2 Produced by Dr P Cross (Chair), Dr A Chandra, Dr T Giles, Dr S Johnson, Dr G Kocjan, Dr D Poller and Professor T Stephenson. The authors are all consultant cellular pathologists, reporting thyroid histology and/or cytology, some of whom hold or have held

2016 Royal College of Pathologists

14. Subacute Thyroiditis (Overview)

is important; because it is self-limiting, no specific treatment, such as antithyroid or thyroid hormone replacement therapy, is necessary in most patients. (See Presentation, Workup, and Treatment.) In general, the following three forms of subacute thyroiditis are recognized: Subacute granulomatous thyroiditis - Also known as subacute painful or de Quervain thyroiditis (see the image below) [ ] Subacute lymphocytic thyroiditis - Also known as subacute painless thyroiditis Subacute postpartum thyroiditis (...) Three multinucleated, giant cell granulomas observed in a fine-needle aspiration biopsy of the thyroid; from a patient with thyrotoxicosis resulting from subacute granulomatous thyroiditis. Disease course Although the etiology appears to be different for the three subtypes, the clinical courses are the same. High thyroid hormone levels result from the destruction of the thyroid follicle and the release of preformed into the circulation, with thyrotoxicosis consequently developing. (The high thyroid

2014 eMedicine.com

15. Thyroiditis, Subacute (Overview)

is important; because it is self-limiting, no specific treatment, such as antithyroid or thyroid hormone replacement therapy, is necessary in most patients. (See Presentation, Workup, and Treatment.) In general, the following three forms of subacute thyroiditis are recognized: Subacute granulomatous thyroiditis - Also known as subacute painful or de Quervain thyroiditis (see the image below) [ ] Subacute lymphocytic thyroiditis - Also known as subacute painless thyroiditis Subacute postpartum thyroiditis (...) Three multinucleated, giant cell granulomas observed in a fine-needle aspiration biopsy of the thyroid; from a patient with thyrotoxicosis resulting from subacute granulomatous thyroiditis. Disease course Although the etiology appears to be different for the three subtypes, the clinical courses are the same. High thyroid hormone levels result from the destruction of the thyroid follicle and the release of preformed into the circulation, with thyrotoxicosis consequently developing. (The high thyroid

2014 eMedicine.com

16. Subacute Thyroiditis (Diagnosis)

is important; because it is self-limiting, no specific treatment, such as antithyroid or thyroid hormone replacement therapy, is necessary in most patients. (See Presentation, Workup, and Treatment.) In general, the following three forms of subacute thyroiditis are recognized: Subacute granulomatous thyroiditis - Also known as subacute painful or de Quervain thyroiditis (see the image below) [ ] Subacute lymphocytic thyroiditis - Also known as subacute painless thyroiditis Subacute postpartum thyroiditis (...) Three multinucleated, giant cell granulomas observed in a fine-needle aspiration biopsy of the thyroid; from a patient with thyrotoxicosis resulting from subacute granulomatous thyroiditis. Disease course Although the etiology appears to be different for the three subtypes, the clinical courses are the same. High thyroid hormone levels result from the destruction of the thyroid follicle and the release of preformed into the circulation, with thyrotoxicosis consequently developing. (The high thyroid

2014 eMedicine.com

17. Thyroiditis, Subacute (Diagnosis)

is important; because it is self-limiting, no specific treatment, such as antithyroid or thyroid hormone replacement therapy, is necessary in most patients. (See Presentation, Workup, and Treatment.) In general, the following three forms of subacute thyroiditis are recognized: Subacute granulomatous thyroiditis - Also known as subacute painful or de Quervain thyroiditis (see the image below) [ ] Subacute lymphocytic thyroiditis - Also known as subacute painless thyroiditis Subacute postpartum thyroiditis (...) Three multinucleated, giant cell granulomas observed in a fine-needle aspiration biopsy of the thyroid; from a patient with thyrotoxicosis resulting from subacute granulomatous thyroiditis. Disease course Although the etiology appears to be different for the three subtypes, the clinical courses are the same. High thyroid hormone levels result from the destruction of the thyroid follicle and the release of preformed into the circulation, with thyrotoxicosis consequently developing. (The high thyroid

2014 eMedicine.com

18. Thyroiditis, Subacute (Follow-up)

== processing > Subacute Thyroiditis Treatment & Management Updated: Oct 08, 2018 Author: Stephanie L Lee, MD, PhD; Chief Editor: Romesh Khardori, MD, PhD, FACP Share Email Print Feedback Close Sections Sections Subacute Thyroiditis Treatment Approach Considerations The treatment of subacute thyroiditis is generally supportive to reduce the symptoms of thyrotoxicosis and to control neck pain in the setting of subacute granulomatous thyroiditis. Because no new hormone is being made, antithyroid medications (...) are not effective in these conditions. Although the abnormal thyroid levels are temporary, emotional support is often necessary. [ , ] Patients are often dehydrated from thyrotoxicosis; encourage all patients to drink 6-8 cups per day of noncaffeinated fluids. Surgical care is almost never recommended for subacute thyroiditis. In rare cases, surgery is recommended for patients who have frequent recurrences of thyrotoxicosis from subacute lymphocytic thyroiditis or recurrent pain from subacute granulomatous

2014 eMedicine.com

19. Subacute Thyroiditis (Follow-up)

== processing > Subacute Thyroiditis Treatment & Management Updated: Oct 08, 2018 Author: Stephanie L Lee, MD, PhD; Chief Editor: Romesh Khardori, MD, PhD, FACP Share Email Print Feedback Close Sections Sections Subacute Thyroiditis Treatment Approach Considerations The treatment of subacute thyroiditis is generally supportive to reduce the symptoms of thyrotoxicosis and to control neck pain in the setting of subacute granulomatous thyroiditis. Because no new hormone is being made, antithyroid medications (...) are not effective in these conditions. Although the abnormal thyroid levels are temporary, emotional support is often necessary. [ , ] Patients are often dehydrated from thyrotoxicosis; encourage all patients to drink 6-8 cups per day of noncaffeinated fluids. Surgical care is almost never recommended for subacute thyroiditis. In rare cases, surgery is recommended for patients who have frequent recurrences of thyrotoxicosis from subacute lymphocytic thyroiditis or recurrent pain from subacute granulomatous

2014 eMedicine.com

20. Subacute Thyroiditis (Treatment)

== processing > Subacute Thyroiditis Treatment & Management Updated: Oct 08, 2018 Author: Stephanie L Lee, MD, PhD; Chief Editor: Romesh Khardori, MD, PhD, FACP Share Email Print Feedback Close Sections Sections Subacute Thyroiditis Treatment Approach Considerations The treatment of subacute thyroiditis is generally supportive to reduce the symptoms of thyrotoxicosis and to control neck pain in the setting of subacute granulomatous thyroiditis. Because no new hormone is being made, antithyroid medications (...) are not effective in these conditions. Although the abnormal thyroid levels are temporary, emotional support is often necessary. [ , ] Patients are often dehydrated from thyrotoxicosis; encourage all patients to drink 6-8 cups per day of noncaffeinated fluids. Surgical care is almost never recommended for subacute thyroiditis. In rare cases, surgery is recommended for patients who have frequent recurrences of thyrotoxicosis from subacute lymphocytic thyroiditis or recurrent pain from subacute granulomatous

2014 eMedicine.com

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