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Stimulant Use Disorder

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41. Efficacy and Safety of Deep Transcranial Magnetic Stimulation for Obsessive-Compulsive Disorder: A Prospective Multicenter Randomized Double-Blind Placebo-Controlled Trial

Efficacy and Safety of Deep Transcranial Magnetic Stimulation for Obsessive-Compulsive Disorder: A Prospective Multicenter Randomized Double-Blind Placebo-Controlled Trial Obsessive-compulsive disorder (OCD) is a chronic and disabling condition that often responds unsatisfactorily to pharmacological and psychological treatments. Converging evidence suggests a dysfunction of the cortical-striatal-thalamic-cortical circuit in OCD, and a previous feasibility study indicated beneficial effects (...) of deep transcranial magnetic stimulation (dTMS) targeting the medial prefrontal cortex and the anterior cingulate cortex. The authors examined the therapeutic effect of dTMS in a multicenter double-blind sham-controlled study.At 11 centers, 99 OCD patients were randomly allocated to treatment with either high-frequency (20 Hz) or sham dTMS and received daily treatments following individualized symptom provocation, for 6 weeks. Clinical response to treatment was determined using the Yale-Brown

2019 EvidenceUpdates

42. Comparative effectiveness of neuroablation and deep brain stimulation for treatment-resistant obsessive-compulsive disorder: a meta-analytic study

Comparative effectiveness of neuroablation and deep brain stimulation for treatment-resistant obsessive-compulsive disorder: a meta-analytic study The safety and efficacy of neuroablation (ABL) and deep brain stimulation (DBS) for treatment refractory obsessive-compulsive disorder (OCD) has not been examined. This study sought to generate a definitive comparative effectiveness model of these therapies.A EMBASE/PubMed search of English-language, peer-reviewed articles reporting ABL and DBS (...) for OCD was performed in January 2018. Change in quality of life (QOL) was quantified based on the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) and the impact of complications on QOL was assessed. Mean response of Y-BOCS was determined using random-effects, inverse-variance weighted meta-analysis of observational data.Across 56 studies, totalling 681 cases (367 ABL; 314 DBS), ABL exhibited greater overall utility than DBS. Pooled ability to reduce Y-BOCS scores was 50.4% (±22.7%) for ABL

2019 EvidenceUpdates

43. Theta-Burst Transcranial Magnetic Stimulation for Posttraumatic Stress Disorder

Theta-Burst Transcranial Magnetic Stimulation for Posttraumatic Stress Disorder Posttraumatic stress disorder (PTSD) is a highly prevalent psychiatric disorder associated with disruption in social and occupational function. Transcranial magnetic stimulation (TMS) represents a novel approach to PTSD, and intermittent theta-burst stimulation (iTBS) is a new, more rapid administration protocol with data supporting efficacy in depression. The authors conducted a sham-controlled study of iTBS (...) for PTSD.Fifty veterans with PTSD received 10 days of sham-controlled iTBS (1,800 pulses/day), followed by 10 unblinded sessions. Primary outcome measures included acceptability (retention rates), changes in PTSD symptoms (clinician- and self-rated), quality of life, social and occupational function, and depression, obtained at the end of 2 weeks; analysis of variance was used to compare active with sham stimulation. Secondary outcomes were evaluated 1 month after treatment, using mixed-model analyses

2019 EvidenceUpdates

44. Opioid Use Disorder - Diagnosis and Management in Primary Care

Opioid Use Disorder - Diagnosis and Management in Primary Care Opioid Use Disorder - Diagnosis and Management in Primary Care - Province of British Columbia theme_3_collection theme_3_frontend theme_3_collection theme_3_frontend Birth, Adoption, Death, Marriage & Divorce theme_1_collection theme_1_frontend theme_1_collection theme_1_frontend British Columbians & Our Governments theme_data_collection data_frontend theme_data_collection data_frontend Data theme_5_collection theme_5_frontend (...) theme_10_collection theme_10_frontend Sports, Recreation, Arts & Culture theme_8_collection theme_8_frontend theme_8_collection theme_8_frontend Taxes & Tax Credits theme_14_collection theme_14_frontend theme_14_collection theme_14_frontend Tourism & Immigration Search default_collection default_frontend Section Navigation Opioid Use Disorder - Diagnosis and Management in Primary Care Effective Date: June 1 st , 2018 Recommendations and Topics Scope This guideline presents recommendations for the diagnosis

2018 Clinical Practice Guidelines and Protocols in British Columbia

45. Substance use disorders in pregnancy: clinical, ethical, and research imperatives of the opioid epidemic

Substance use disorders in pregnancy: clinical, ethical, and research imperatives of the opioid epidemic Substance use disorders in pregnancy: clinical, ethical, and research imperatives of the opioid epidemic: a report of a joint workshop of the Society for Maternal-Fetal Medicine, American College of Obstetricians and Gynecologists, and American Society of Addiction Medicine - American Journal of Obstetrics & Gynecology Email/Username: Password: Remember me Search Terms Search within Search (...) Share this page: Access provided by Volume 221, Issue 1, Pages B5–B28 Substance use disorders in pregnancy: clinical, ethical, and research imperatives of the opioid epidemic: a report of a joint workshop of the Society for Maternal-Fetal Medicine, American College of Obstetricians and Gynecologists, and American Society of Addiction Medicine The workshop was convened at the 38th Annual Pregnancy Meeting of the Society for Maternal-Fetal Medicine in Dallas, TX, January 29–February 2, 2018. x Jeffrey

2019 Society for Maternal-Fetal Medicine

46. Use of electronic screen media prior to dental appointment can help to reduce anxiety in patients with Autism Spectrum Disorder

Use of electronic screen media prior to dental appointment can help to reduce anxiety in patients with Autism Spectrum Disorder UTCAT3390, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Use of electronic screen media prior to dental appointment can help to reduce anxiety in patients with Autism Spectrum Disorder Clinical Question Can use of electronic screen media prior to dental appointment help reduce anxiety (...) in patients with Autism Spectrum Disorder? Clinical Bottom Line For children with Autism Spectrum Disorder (ASD), certain types of electronic screen media may be helpful to reduce anxiety during dental appointments. This randomized controlled study based on 80 subjects found that electronic screen media could be used to reduce anxiety in children with ASD. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Isong

2019 UTHSCSA Dental School CAT Library

47. Recovery schools for improving behavioral and academic outcomes among students in recovery from substance use disorders: a systematic review

Recovery schools for improving behavioral and academic outcomes among students in recovery from substance use disorders: a systematic review A Campbell Systematic Review 2018:9 Education Coordinating Group Emily A. Hennessy, Emily E. Tanner-Smith, Andrew J. Finch, Nila Sathe, Shannon Kugley Recovery schools for improving behavioral and academic outcomes among students in recovery from substance use disorders: a systematic review Published: October 2018 Search executed: September 2018The (...) Campbell Library comprises: • Systematic reviews (titles, protocols and reviews) • Policies and Guidelines Series • Methods Series Go to the library to download these resources, at: www.campbellcollaboration.org/library/ Better evidence for a better world Colophon Title Recovery schools for improving behavioral and academic outcomes among students in recovery from substance use disorders: a systematic review Authors 1 Emily A. Hennessy 2 Emily E. Tanner-Smith 3 Andrew J. Finch 4 Nila Sathe 5 Shannon

2018 Campbell Collaboration

48. Non-medical Prescription Stimulant Use among Post-secondary Students

stimulants, for example Ritalin® (methylphenidate) or Adderall® (amphetamine), are often used to treat attention deficit hyperactivity disorder (ADHD) (Canadian Centre on Substance Abuse, 2016a). Prescription stimulants used as prescribed can be of significant benefit to those who need them. However, the inappropriate use of these drugs can lead to significant harm, and is of particular concern with respect to emerging adults, aged 18–25 (Lakhan & Kirchgessner, 2012; McCabe, Knight, Teter, & Wechsler (...) disorders among young adult women. A study of female university students screened them for an eating disorder, determining those who were at low risk, at high risk or who already had a clinical diagnosis. Ten percent of this group reported inappropriate stimulant use and those who so reported had a greater clinical severity of eating disorder (i.e., those at high risk or those with a subclinical or clinical eating disorder)(Gibbs et al, 2016). It has been suggested that healthcare practitioners who

2018 Canadian Centre on Substance Abuse

49. What rodent models of deep brain stimulation can teach us about the neural circuit regulation of prepulse inhibition in neuropsychiatric disorders. (PubMed)

What rodent models of deep brain stimulation can teach us about the neural circuit regulation of prepulse inhibition in neuropsychiatric disorders. Deep brain stimulation (DBS) is routinely used for treatment of movement disorders and it is also under investigation for neuropsychiatric disorders with deficient sensorimotor gating, such as schizophrenia, Tourette's syndrome and obsessive compulsive disorder. Electrical stimulation induces excitation and inhibition both at the stimulation site (...) the neuronal circuit regulation that is of relevance to PPI and its deficits in neuropsychiatric disorders with disturbed sensorimotor gating. Finally, we report on the use of the PPI paradigm in human patients operated for DBS on/off stimulation, which may further elucidate the neuronal network involved in regulation of PPI.Copyright © 2017 Elsevier B.V. All rights reserved.

2017 Schizophrenia Research

50. Specific impact of stimulant, alcohol and cannabis use disorders on first-episode psychosis: 2-year functional and symptomatic outcomes. (PubMed)

Specific impact of stimulant, alcohol and cannabis use disorders on first-episode psychosis: 2-year functional and symptomatic outcomes. Many studies have concluded that cannabis use disorder (CUD) negatively influences outcomes in first-episode psychosis (FEP). However, few have taken into account the impact of concurrent misuse of other substances.This 2-year, prospective, longitudinal study of FEP patients, aged between 18 and 30 years, admitted to early intervention programs in Montreal (...) , Quebec, Canada, examined the specific influence of different substance use disorders (SUD) (alcohol, cannabis, cocaine, amphetamines) on service utilization, symptomatic and functional outcomes in FEP.Drugs and alcohol were associated with lower functioning, but drugs had a greater negative impact on most measures at 2-year follow-up. Half of CUD patients and more than 65% of cocaine or amphetamine abusers presented polysubstance use disorder (poly-SUD). The only group that deteriorated from years 1

2017 Psychological Medicine

51. Deep Transcranial Magnetic Stimulation of the Dorsolateral Prefrontal Cortex in Alcohol Use Disorder Patients: Effects on Dopamine Transporter Availability and Alcohol Intake. (PubMed)

Deep Transcranial Magnetic Stimulation of the Dorsolateral Prefrontal Cortex in Alcohol Use Disorder Patients: Effects on Dopamine Transporter Availability and Alcohol Intake. Repetitive Transcranial Magnetic Stimulation (rTMS) of the dorsolateral prefrontal cortex may affect neuro-adaptations associated with alcohol use disorder (AUD), potentially influencing craving and alcohol intake. We investigated alcohol intake and dopamine transporter (DAT) availability by Single Photon Emission (...) Computed Tomography (SPECT) in the striatum of AUD patients before and after deep rTMS. Fourteen patients underwent baseline clinical and SPECT assessment. Eleven out of fourteen patients were randomized into two groups for the REAL (n.5) or SHAM (n.6) treatment. Clinical and SPECT evaluations were then carried out after four weeks of rTMS sessions (T1). At baseline, AUD patients showed higher striatal DAT availability than healthy control subjects (HC). Patients receiving the REAL stimulation revealed

2017 European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology

52. Transcranial Direct Current Stimulation in Substance Use Disorders: A Systematic Review of Scientific Literature. (PubMed)

Transcranial Direct Current Stimulation in Substance Use Disorders: A Systematic Review of Scientific Literature. New treatment options such as noninvasive brain stimulation have been recently explored in the field of substance use disorders (SUDs), including transcranial direct current stimulation (tDCS).In light of this, we have performed a review of the scientific literature to assess efficacy and technical and methodological issues resulting from applying tDCS to the field of SUDs.Our (...) scientific papers were selected out of 48 articles. Among these, 16 studied the efficacy of tDCS applied to the dorsolateral prefrontal cortex, and 8 suggested the efficacy of tDCS in reducing substance craving.In light of these data, it is premature to conclude that tDCS over the dorsolateral prefrontal cortex is a very efficient technique in reducing craving. Small sample size, different stimulation protocols, and study duration were the main limitations. However, the efficacy of tDCS in treating SUDs

2017 The journal of ECT

53. Repetitive Transcranial Magnetic Stimulation in Patients With Opioid Use Disorders

Repetitive Transcranial Magnetic Stimulation in Patients With Opioid Use Disorders Repetitive Transcranial Magnetic Stimulation in Patients With Opioid Use Disorders - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Repetitive Transcranial Magnetic Stimulation in Patients With Opioid Use Disorders The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03229642 Recruitment Status : Recruiting First Posted : July 25, 2017 Last

2017 Clinical Trials

54. Transcranial Direct Current Stimulation to Modulate Top-Down Regulation for Drug Craving in Methamphetamine Use Disorder

Transcranial Direct Current Stimulation to Modulate Top-Down Regulation for Drug Craving in Methamphetamine Use Disorder Transcranial Direct Current Stimulation to Modulate Top-Down Regulation for Drug Craving in Methamphetamine Use Disorder - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum (...) number of saved studies (100). Please remove one or more studies before adding more. Transcranial Direct Current Stimulation to Modulate Top-Down Regulation for Drug Craving in Methamphetamine Use Disorder (NeuroMethDC) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our

2017 Clinical Trials

55. A Preliminary Investigation of Pre-Frontal Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Cannabis Use Disorder

A Preliminary Investigation of Pre-Frontal Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Cannabis Use Disorder A Preliminary Investigation of Pre-Frontal Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Cannabis Use Disorder - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study (...) Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Preliminary Investigation of Pre-Frontal Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Cannabis Use Disorder The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care

2017 Clinical Trials

56. Transcranial Magnetic Stimulation for the Treatment of Veterans With Alcohol Use Disorders

Transcranial Magnetic Stimulation for the Treatment of Veterans With Alcohol Use Disorders Transcranial Magnetic Stimulation for the Treatment of Veterans With Alcohol Use Disorders - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) studies before adding more. Transcranial Magnetic Stimulation for the Treatment of Veterans With Alcohol Use Disorders The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03191266 Recruitment Status : Recruiting First Posted

2017 Clinical Trials

57. Insular and Cingulate Attenuation during Decision Making is associated with Future Transition to Stimulant Use Disorder (PubMed)

Insular and Cingulate Attenuation during Decision Making is associated with Future Transition to Stimulant Use Disorder To understand processes placing individuals at risk for stimulant (amphetamine and cocaine) use disorder.Longitudinal study.University of California, San Diego Department of Psychiatry, CA, USA.Occasional stimulant users (OSU; n = 184) underwent a baseline clinical interview and a functional magnetic resonance imaging (fMRI) session. On the basis of a follow-up clinical (...) interview completed 3 years later, OSU (n = 147) were then categorized as problem stimulant users (PSU: n = 36; those who developed stimulant use disorders in the interim) or desisted stimulant users (DSU: n = 74; those who stopped using). OSU who did not meet criteria for PSU or DSU (n = 37) were included in dimensional analyses.fMRI blood oxygen level-dependent (BOLD) contrast percentage signal change from baseline collected during a Paper-Scissors-Rock task was examined during three decision-making

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2017 Addiction (Abingdon, England)

58. SNORAP: A Device for the Correction of Impaired Sleep Health by Using Tactile Stimulation for Individuals with Mild and Moderate Sleep Disordered Breathing (PubMed)

SNORAP: A Device for the Correction of Impaired Sleep Health by Using Tactile Stimulation for Individuals with Mild and Moderate Sleep Disordered Breathing Sleep physiology and sleep hygiene play significant roles in maintaining the daily lives of individuals given that sleep is an important physiological need to protect the functions of the human brain. Sleep disordered breathing (SDB) is an important disease that disturbs this need. Snoring and Obstructive Sleep Apnea Syndrome (OSAS (...) we named SNORAP) were applied to five volunteer patients (male, mean age: 33.2, body mass index mean: 29.3). After receiving the sound in real time with the microphone, the snoring sound was detected by using the Audio Fingerprint method with a success rate of 98.9%. According to the results obtained, the severity and the number of the snoring of the patients using SNORAP were found to be significantly lower than in the experimental conditions in the apnea hypopnea index (AHI), apnea index

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2017 Sensors (Basel, Switzerland)

59. Developing Repetitive Transcranial Magnetic Stimulation (rTMS) as a Treatment Tool for Cocaine Use Disorder: a Series of Six Translational Studies (PubMed)

Developing Repetitive Transcranial Magnetic Stimulation (rTMS) as a Treatment Tool for Cocaine Use Disorder: a Series of Six Translational Studies Cocaine dependence is a chronic and relapsing disorder which is particularly resistant to behavioral or pharmacologic treatment, and likely involves multiple dysfunctional frontal-striatal circuits. Through advances in preclinical research in the last decade, we now have an unprecedented understanding of the neural control of drug-taking behavior (...) and empirically developing a non-invasive, neural circuit-based intervention for cocaine use disorder. Utilizing a multimodal approach of functional brain imaging and brain stimulation, we have attempted to design and optimize a repetitive transcranial magnetic stimulation treatment protocol for cocaine use disorder. This manuscript will briefly review the data largely from our own lab that motivated our selection of candidate neural circuits, and then summarize the results of six studies, culminating

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2017 Current behavioral neuroscience reports

60. Updated Review on the Clinical Use of Repetitive Transcranial Magnetic Stimulation in Psychiatric Disorders (PubMed)

Updated Review on the Clinical Use of Repetitive Transcranial Magnetic Stimulation in Psychiatric Disorders With the ability to modulate cortical activity, repetitive transcranial magnetic stimulation (rTMS) is becoming increasingly important in clinical applications for psychiatric disorders. Previous studies have demonstrated its promising efficacy in depression and schizophrenia, and emerging evidence has also been found in patients with anxiety disorder, obsessive-compulsive disorder (...) and the optimal protocol of rTMS in psychiatric disorders, especially for medication-resistant symptoms.

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2017 Neuroscience bulletin

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