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Stimulant Use Disorder

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21. Transcranial Direct Current Stimulation Reduces Craving in Substance Use Disorders: A Double-blind, Placebo-Controlled Study. (Abstract)

Transcranial Direct Current Stimulation Reduces Craving in Substance Use Disorders: A Double-blind, Placebo-Controlled Study. The use of transcranial direct current stimulation (tDCS) in addiction disorders is still on its rise in comparison with pharmacological and psychotherapeutic strategies that still show low level of evidence. In this study, we aimed to evaluate the efficacy of the anodic tDCS for the short-term treatment of substance craving and other psychiatric symptoms.In (...) this randomized, double-blind, sham-controlled trial, inclusion criteria included the diagnosis of substance use disorder and/or gambling disorder. The protocol includes 5 consecutive days of active or sham tDCS session. Cathode was placed over the left dorsolateral prefrontal cortex. Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale, Young Mania Rating Scale, Barratt Impulsiveness Scale, South Oaks Gambling Screen, and visual analog scale (VAS) 1 to 10 for craving were administered

2019 The journal of ECT Controlled trial quality: predicted high

22. The use of transcranial magnetic stimulation as a treatment for movement disorders: A critical review. (Abstract)

diseases. In this article, we illustrate the basic principles on which the therapeutic use of transcranial magnetic stimulation is based and review the clinical trials that have been performed in patients with movement disorders.A search of the PubMed database for research and review articles was performed on therapeutic applications of transcranial magnetic stimulation in movement disorders. The search included the following conditions: Parkinson's disease, dystonia, Tourette syndrome and other (...) chronic tic disorders, Huntington's disease and choreas, and essential tremor. The results of the studies and possible mechanistic explanations for the relatively minor effects of transcranial magnetic stimulation are discussed. Possible ways to improve the methodology and achieve greater therapeutic efficacy are discussed.Despite the promising and robust rationales for the use of transcranial magnetic stimulations as a treatment tool in movement disorders, the results taken as a whole

2019 Movement Disorders

23. Use of machine learning in predicting clinical response to transcranial magnetic stimulation in comorbid posttraumatic stress disorder and major depression: A resting state electroencephalography study. (Abstract)

Use of machine learning in predicting clinical response to transcranial magnetic stimulation in comorbid posttraumatic stress disorder and major depression: A resting state electroencephalography study. Repetitive transcranial magnetic stimulation (TMS) is clinically effective for major depressive disorder (MDD) and investigational for other conditions including posttraumatic stress disorder (PTSD). Understanding the mechanisms of TMS action and developing biomarkers predicting response remain (...) important goals. We applied a combination of machine learning and electroencephalography (EEG), testing whether machine learning analysis of EEG coherence would (1) predict clinical outcomes in individuals with comorbid MDD and PTSD, and (2) determine whether an individual had received a TMS course.We collected resting-state 8-channel EEG before and after TMS (5 Hz to the left dorsolateral prefrontal cortex). We used Lasso regression and Support Vector Machine (SVM) to test the hypothesis that baseline

2019 Journal of Affective Disorders

24. Canadian guidelines on cannabis use disorder among older adults

disorders, problematic substance use, or substance use disorder (SUD). b) Cognitive impairment, cardiovascular disease, cardiac arrhythmias, coronary artery disease, unstable blood pressure, or impaired balance. Regular cannabis smoking can lead to chronic bronchitis and respiratory symptoms. (11) Cannabis in other forms may cause osteoporosis, and cannabis can impair cognitive and motor functions. (12) Clinical case reports and case series have indicated that regular cannabis use can be associated (...) be avoided by older adults who have: a) A history of, or are currently experiencing, mental health disorders, problematic substance use, or Substance Use Disorder (SUD). [GRADE: Evidence: Moderate; Strength: Strong] b) Cognitive impairment, cardiovascular disease, cardiac arrhythmias, coronary artery disease, unstable blood pressure, or impaired balance. [GRADE: Evidence: Moderate; Strength: Strong] Recommendation #2: Clinicians should be aware of the following: a) The current evidence base

2020 CPG Infobase

25. Electrical stimulation of the lower oesophageal sphincter for treating gastro-oesophageal reflux disease

. 1 1 Recommendations Recommendations 1.1 Current evidence on the safety and efficacy of electrical stimulation of the lower oesophageal sphincter for treating gastro-oesophageal reflux disease © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 1 of 10(GORD) is limited in quantity and quality. Therefore, this procedure should only be used in the context of research. 1.2 NICE encourages clinicians to enter patients (...) . Electrical stimulation of the lower oesophageal sphincter for treating gastro-oesophageal reflux disease (IPG540) © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 103.2 With the patient under general anaesthesia, 2 electrodes and a lead are implanted into the sphincter muscle using a laparoscope under endoscopic guidance. The lead is passed through the abdominal wall and is secured to a stimulator, which is implanted

2016 National Institute for Health and Clinical Excellence - Interventional Procedures

26. Effects of Tonic Spinal Cord Stimulation on External Mechanical and Thermal Stimuli Perception Using Quantitative Sensory Testing: A Multicenter Stimulation ON-OFF Study on Chronic Pain Patients. (Abstract)

on the sensory perception of chronic pain patients using quantitative sensory testing (QST).Forty-eight patients (mean age: 57 y) with chronic leg pain due to failed back surgery syndrome or complex regional pain syndrome treated with SCS were recruited from 3 research centers. Test procedures included 2 sessions (stimulation On or Off), with measures of detection thresholds for heat, touch, vibration, and of pain thresholds for cold, heat, pressure, the assessment of dynamic mechanical allodynia (...) Effects of Tonic Spinal Cord Stimulation on External Mechanical and Thermal Stimuli Perception Using Quantitative Sensory Testing: A Multicenter Stimulation ON-OFF Study on Chronic Pain Patients. Tonic spinal cord stimulation (SCS) is currently used to treat neuropathic pain. With this type of stimulation, an implantable pulse generator generates electrical paresthesias in the affected area through 1 or more epidural leads. The goal of this study was to evaluate the impact of tonic SCS

2020 Clinical Journal of Pain

27. Author Correction: A novel oocyte maturation trigger using 1500 IU of human chorionic gonadotropin plus 450 IU of follicle-stimulating hormone may decrease ovarian hyperstimulation syndrome across all in vitro fertilization stimulation protocols Full Text available with Trip Pro

Author Correction: A novel oocyte maturation trigger using 1500 IU of human chorionic gonadotropin plus 450 IU of follicle-stimulating hormone may decrease ovarian hyperstimulation syndrome across all in vitro fertilization stimulation protocols The original version of this article unfortunately contained a mistake. The middle initial of Douglas A. Mata was omitted. The original article has been corrected.

2017 Journal of assisted reproduction and genetics

28. Low frequency right transcranial magnetic stimulation for major depressive disorder

effect and thereby produces antidepressant results. Patient Population: LFrTMS is used to treat a number of disorders including, but not limited to, schizophrenia, obsessive compulsive disorder, and tinnitus. This health technology assessment is specifically focused on the therapeutic use of LFrTMS for treatment-resistant MDD in adults. Clinical Alternatives: Transcranial magnetic stimulation was initially developed as a physiologically similar but potentially more acceptable alternative (...) Low frequency right transcranial magnetic stimulation for major depressive disorder Low frequency right transcranial magnetic stimulation for major depressive disorder Low frequency right transcranial magnetic stimulation for major depressive disorder HAYES, Inc. Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation HAYES, Inc.. Low frequency right transcranial

2017 Health Technology Assessment (HTA) Database.

29. High-frequency left repetitive transcranial magnetic stimulation for treatment-resistant major depressive disorder

High-frequency left repetitive transcranial magnetic stimulation for treatment-resistant major depressive disorder High-frequency left repetitive transcranial magnetic stimulation for treatment-resistant major depressive disorder High-frequency left repetitive transcranial magnetic stimulation for treatment-resistant major depressive disorder HAYES, Inc. Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has (...) been made for the HTA database. Citation HAYES, Inc.. High-frequency left repetitive transcranial magnetic stimulation for treatment-resistant major depressive disorder . Lansdale: HAYES, Inc.. Directory Publication. 2016 Authors' objectives Repetitive high-frequency left transcranial magnetic stimulation (HFL-rTMS) is a noninvasive technique that may serve as an alternative intervention for treatment-resistant depression (TRD). Brief repetitive pulses of magnetic energy are applied to the scalp

2017 Health Technology Assessment (HTA) Database.

30. Dorsal root ganglion stimulation for the treatment of complex regional pain syndrome

of DRG stimulation for the relief of CRPS compared with traditional and newer SCS systems is unknown. Key Questions: Is dorsal root ganglion (DRG) stimulation effective in treating chronic complex regional pain syndrome (CRPS) in adults? How does DRG stimulation compare with spinal cord stimulation (SCS) or conservative management of CRPS? Is DRG stimulation safe for the treatment of CRPS? Have definitive patient selection criteria been identified for the use of DRG stimulation in CRPS patients (...) Dorsal root ganglion stimulation for the treatment of complex regional pain syndrome Dorsal root ganglion stimulation for the treatment of complex regional pain syndrome Dorsal root ganglion stimulation for the treatment of complex regional pain syndrome HAYES, Inc Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation HAYES, Inc. Dorsal root ganglion stimulation

2017 Health Technology Assessment (HTA) Database.

31. National Trends in and Correlates of Nonmedical Use of Prescription Stimulants, Nonmedical Use Frequency, and Use Disorders. (Abstract)

National Trends in and Correlates of Nonmedical Use of Prescription Stimulants, Nonmedical Use Frequency, and Use Disorders. To examine national trends in and correlates of nonmedical use of prescription stimulants, nonmedical use frequency, and use disorders among individuals aged 12-64 years.Data from 783,400 persons aged 12-64 who participated in the 2003-2014 National Surveys on Drug Use and Health (NSDUH). Descriptive analyses and bivariable and multivariable logistic regression and zero (...) , and the prevalence of prescription stimulant use disorders in 2003-2004 was higher than that in 2005-2010, but was similar to that in 2011-2014. Among nonmedical prescription stimulant users aged 12-64 in 2013-2014, 53.2% reported that their source of stimulants used nonmedically last time was from relatives/friends for free. Our study also identified correlates of prescription stimulant nonmedical use, use frequency, and use disorders. Co-occurring substance use disorders are common among those

2017 Journal of Clinical Psychiatry

32. Historical clinical and economic consequences of anemia management in patients with end-stage renal disease on dialysis using erythropoietin stimulating agents versus routine blood transfusions: a retrospective cost-effectiveness analysis Full Text available with Trip Pro

Historical clinical and economic consequences of anemia management in patients with end-stage renal disease on dialysis using erythropoietin stimulating agents versus routine blood transfusions: a retrospective cost-effectiveness analysis Historical clinical and economic consequences of anemia management in patients with end-stage renal disease on dialysis using erythropoietin stimulating agents versus routine blood transfusions: a retrospective cost-effectiveness analysis Historical clinical (...) and economic consequences of anemia management in patients with end-stage renal disease on dialysis using erythropoietin stimulating agents versus routine blood transfusions: a retrospective cost-effectiveness analysis Naci H, de Lissovoy G, Hollenbeak C, Custer B, Hofmann A, McClellan W, Gitlin M Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed

2012 NHS Economic Evaluation Database.

33. Effect of footplate neuromuscular electrical stimulation on functional and quality-of-life parameters in patients with peripheral artery disease: pilot, and subsequent randomized clinical trial (Abstract)

Effect of footplate neuromuscular electrical stimulation on functional and quality-of-life parameters in patients with peripheral artery disease: pilot, and subsequent randomized clinical trial Supervised exercise programmes for intermittent claudication have poor access and limited compliance. Neuromuscular electrical stimulation (NMES) may be an effective alternative. A proof-of-concept study and RCT were conducted.In study 1, eligible patients underwent baseline assessment; treadmill testing (...) for initial (ICD) and maximum (MCD) claudication distance; EuroQoL Five Dimensions five-level instrument (EQ-5D-5L™) and Intermittent Claudication Questionnaire (ICQ) assessment; and measurement of ultrasound haemodynamics of the superficial femoral artery. After familiarization with the NMES device, participants underwent a 30-min session of stimulation with concomitant recording of haemodynamic measures at 15 min, and after device cessation. Measurements were repeated after 6 weeks of daily use of NMES

2020 EvidenceUpdates

34. Efficacy and safety of repetitive transcranial magnetic stimulation using an H1-coil or figure-8-coil in the treatment of unipolar major depressive disorder: A study protocol for a randomized controlled trial. Full Text available with Trip Pro

Efficacy and safety of repetitive transcranial magnetic stimulation using an H1-coil or figure-8-coil in the treatment of unipolar major depressive disorder: A study protocol for a randomized controlled trial. Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive technique with few side effects that has been reported to be effective in the treatment of major depressive disorder (MDD). At present, no randomized controlled trials (RCT) have compared the efficacy and safety of rTMS (...) delivered by the figure-8-coil and the H1-coil. We describe an industry-independent, randomized, controlled, single-blinded, single-center study protocol assessing the differences in efficacy and safety of rTMS for patients diagnosed with MDD with the H1-coil and figure-8-coil as an add-on to stable pharmacotherapy or pharmacotherapy alone. Stimulation protocols follow those that led to the FDA clearance of these treatments for MDD. The sample of 76 patents in each of the three groups will be enrolled

2018 Psychiatria Danubina Controlled trial quality: uncertain

35. High frequency repetitive transcranial magnetic stimulation of the left dorsolateral prefrontal cortex for methamphetamine use disorders: A randomised clinical trial. (Abstract)

High frequency repetitive transcranial magnetic stimulation of the left dorsolateral prefrontal cortex for methamphetamine use disorders: A randomised clinical trial. Repetitive transcranial magnetic stimulation (rTMS) is a brain stimulation and modulation electrophysiological technique, it can change cortical excitability of target brain region, modulate neuron plasticity and brain connections. Previous researches indicated that rTMS could reduce cue-induced craving in drug addiction.In (...) after 5 sessions of rTMS as compared to sham stimulation. Furthermore, real rTMS improved verbal learning and memory and social cognition in MA-addicted patients.The present study suggests that 10Hz rTMS of the left DLPFC may reduce craving and have no negative effects on cognitive function in MA-addicted patients, supporting the safety of rTMS in treating MA addiction.Copyright © 2017 Elsevier B.V. All rights reserved.

2018 Drug and alcohol dependence Controlled trial quality: uncertain

36. Longitudinal Trends in the Diagnosis of Attention-Deficit/Hyperactivity Disorder and Stimulant Use in Preschool Children on Medicaid. (Abstract)

Longitudinal Trends in the Diagnosis of Attention-Deficit/Hyperactivity Disorder and Stimulant Use in Preschool Children on Medicaid. To describe trends in the diagnosis of attention-deficit/hyperactivity disorder (ADHD) and prescribing of stimulants in preschool-age children receiving Medicaid and to identify factors associated with the receipt of psychosocial care.Data were extracted from 2012-2016 Kentucky Medicaid claims for children aged <6 years. ADHD was identified using International (...) Classification of Diseases, Tenth Revision codes F90.0, F90.1, F90.2, F90.8, and F90.9. Psychosocial therapy was defined as having at least 1 relevant Current Procedural Terminology code in a claim within the year. A generalized linear model with a logit link and binomial distribution was used to assess factors associated with receipt of psychosocial treatment in 2016.More than 2500 (1.24%) preschool-aged children receiving Medicaid had a diagnosis of ADHD in 2016, with 988 (38.2%) of those receiving

2018 Journal of Pediatrics

37. Investigating the Efficacy of Caloric Vestibular Stimulation in the Treatment of Substance Use Disorders

Recruitment Status : Not yet recruiting First Posted : August 29, 2018 Last Update Posted : March 8, 2019 See Sponsor: Wake Forest University Health Sciences Information provided by (Responsible Party): Wake Forest University Health Sciences Study Details Study Description Go to Brief Summary: The purpose of this study is to determine efficacy and effect of CVS (caloric vestibular stimulation) Condition or disease Intervention/treatment Phase Substance Use Disorders Device: ThermoNeuroModulation TNM (...) by U.S. FDA: No Pediatric Postmarket Surveillance of a Device Product: No Product Manufactured in and Exported from the U.S.: No Keywords provided by Wake Forest University Health Sciences: opiate use disorder neuromodulation caloric vestibular stimulation adjunct therapy Additional relevant MeSH terms: Layout table for MeSH terms Disease Substance-Related Disorders Pathologic Processes Chemically-Induced Disorders Mental Disorders

2018 Clinical Trials

38. Deep Brain Stimulation (DBS) for the Treatment of Refractory Alcohol Use Disorder (AUD): Pilot Trial

addiction and craving behaviours. Condition or disease Intervention/treatment Phase Alcohol Use Disorder Device: Deep Brain Stimulation Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 5 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: Deep Brain Stimulation (DBS) for the Treatment of Refractory Alcohol Use Disorder (AUD): Pilot Trial (...) Deep Brain Stimulation (DBS) for the Treatment of Refractory Alcohol Use Disorder (AUD): Pilot Trial Deep Brain Stimulation (DBS) for the Treatment of Refractory Alcohol Use Disorder (AUD): Pilot Trial - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please

2018 Clinical Trials

39. Add-on Low Dose Dextromethorphan and Memantine in Patients With Amphetamine-type Stimulants Use Disorder

with improvement in inflammatory markers, neurotrophic factors and neuropsychological tests. Condition or disease Intervention/treatment Phase Stimulants Use Disorder Drug: dextromethorphan and memantine (DM+MM) Drug: Placebos Phase 1 Phase 2 Detailed Description: In current study, we will conduct a randomized double-blind placebo-controlled study. We will recruit 100-120 patients with ATSUD in three years and allocate them to add-on low dose dextromethorphan and memantine (DM 30mg/day+MM 5mg/day) or placebo (...) , National Cheng-Kung University Hospital: amphetamine-type stimulants use disorder dextromethorphan memantine inflammation neurodegeneration Additional relevant MeSH terms: Layout table for MeSH terms Disease Pathologic Processes Memantine Amphetamine Dextromethorphan Central Nervous System Stimulants Antiparkinson Agents Anti-Dyskinesia Agents Dopamine Agents Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action Physiological Effects of Drugs Excitatory Amino Acid Antagonists

2018 Clinical Trials

40. Transcranial Magnetic Stimulation in Tourette Syndrome: A Historical Perspective, Its Current Use and the Influence of Comorbidities in Treatment Response Full Text available with Trip Pro

Transcranial Magnetic Stimulation in Tourette Syndrome: A Historical Perspective, Its Current Use and the Influence of Comorbidities in Treatment Response Tourette syndrome (TS) is a childhood-onset neuropsychiatric disorder consisting of impairing motor and vocal tics which often persists adolescent and adult years. In this older refractory group, standard treatments such as pharmacotherapy and psychotherapeutic interventions may only have limited effects. Based on electrical cortical (...) disorders using TMS and imaging targeting neuroplasticity will be discussed.Therapeutic electrical brain activity modulation with TMS has been carried out in stroke neuro-rehabilitation and neuropsychiatry, including trials in TS. Eleven trials document the use of TMS in TS targeting several brain areas, a positive effect is seen for those trials targeting the SMA. In particular, it appears that younger individuals with concurrent attention-deficit hyperactivity disorder (ADHD) benefit the most.TMS can

2018 Brain sciences

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