How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

130 results for

Starvation Ketoacidosis

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

1. Starvation ketoacidosis: Treatment pitfalls (Full text)

Starvation ketoacidosis: Treatment pitfalls 29118847 2018 11 13 1751-1437 18 3 2017 Aug Journal of the Intensive Care Society J Intensive Care Soc Starvation ketoacidosis: Treatment pitfalls. 265 10.1177/1751143716687593 Hammerbeck Henry H Bedford Hospitals NHS Trust, Bedford, UK. Holland Michael R MR Buckinghamshire Healthcare NHS Trust, Buckinghamshire, UK. eng Journal Article 2017 07 24 England J Intensive Care Soc 101538668 1751-1437 2017 11 10 6 0 2017 11 10 6 0 2017 11 10 6 1 ppublish

2017 Journal of the Intensive Care Society PubMed

2. Starvation ketoacidosis (Full text)

Starvation ketoacidosis 28979522 2019 01 16 1751-1437 17 4 2016 Nov Journal of the Intensive Care Society J Intensive Care Soc Starvation ketoacidosis. 356 10.1177/1751143716644462 Frise Charlotte J CJ Oxford University Hospitals NHS Foundation Trust, Oxford, UK. Mackillop Lucy L Oxford University Hospitals NHS Foundation Trust, Oxford, UK. eng Journal Article 2016 10 25 England J Intensive Care Soc 101538668 1751-1437 2017 10 6 6 0 2017 10 6 6 0 2017 10 6 6 1 ppublish 28979522 10.1177

2016 Journal of the Intensive Care Society PubMed

3. Acute starvation ketoacidosis in pregnancy with severe hypertriglyceridemia: A case report. (Full text)

Acute starvation ketoacidosis in pregnancy with severe hypertriglyceridemia: A case report. Pregnant women are more prone to ketosis due to the relative insulin resistance, accelerated lipolysis and increased free fatty acids.We report a pregnant woman with hyperlipidemia, who experienced severe metabolic acidosis after a short period of starvation.Based on her clinical symptoms, exclusion diagnosis and therapeutic diagnosis, her condition was diagnosed as starvation ketoacidosis.An emergency (...) caesarean section under general anesthesia was implemented 2 hours after her admission. The metabolic acidosis was treated with fluid resuscitation using compound sodium lactate, bicarbonate, and 5% dextrose together with insulin 6U.Both mother and baby were discharged clinically well.Starvation ketoacidosis may happen in special patient who was in pregnancy and with severe hypertriglyceridemia, after just one day fasting and vomiting.

2018 Medicine PubMed

4. Post-bariatric surgery starvation ketoacidosis and lipase elevation in the absence of DKA or pancreatitis. (PubMed)

Post-bariatric surgery starvation ketoacidosis and lipase elevation in the absence of DKA or pancreatitis. We report a case of post bariatric surgery by laparoscopic sleeve gastrectomy who presented with post-surgical poor oral tolerance and high anion gap metabolic ketoacidosis, who was initially misdiagnosed with diabetic ketoacidosis and treated with volume supplementation without improvement. The metabolic derangements were found to be caused by starvation ketoacidosis, which (...) was then treated with glucose supplementation, and the anion gap quickly closed. Moreover, this patient also presented with non-pancreatitis lipase elevation. This case highlights the recognition and management of post-bariatric surgery starvation ketoacidosis; additionally, clinicians should be vigilant about the interpretation and management of elevated lipase without clinical pancreatitis.Copyright © 2017. Published by Elsevier Inc.

2017 American Journal of Emergency Medicine

5. Starvation Ketoacidosis as a Cause of Unexplained Metabolic Acidosis in the Perioperative Period (Full text)

Starvation Ketoacidosis as a Cause of Unexplained Metabolic Acidosis in the Perioperative Period BACKGROUND Besides providing anesthesia for surgery, the anesthesiologist's role is to optimize the patient for surgery and for post-surgical recovery. This involves timely identification and treatment of medical comorbidities and abnormal laboratory values that could complicate the patient's perioperative course. There are several potential causes of anion and non-anion gap metabolic acidosis (...) , including lactic acidosis, diabetic ketoacidosis, drug-induced ketoacidosis, ingestion of toxic alcohols (e.g., methanol, ethylene glycol), uremia, and acute renal failure. Laboratory workup was remarkable only for elevated serum and urinary ketone levels, believed to be secondary to starvation ketoacidosis. Due to the patient's unexplained acid-base disturbance, she was kept intubated postoperatively to allow for further workup and management. CONCLUSIONS Starvation ketoacidosis is not widely

2016 The American journal of case reports PubMed

6. Short-term starvation with a near-fatal asthma attack induced ketoacidosis in a nondiabetic pregnant woman: A case report. (Full text)

Short-term starvation with a near-fatal asthma attack induced ketoacidosis in a nondiabetic pregnant woman: A case report. Life-threatening refractory metabolic acidosis due to starvation ketoacidosis is rarely reported, even among nondiabetic pregnant women, and may be overlooked. Furthermore, stressful situations may increase the acidosis severity.In the present case, a nondiabetic multiparous woman was admitted for a near-fatal asthma attack and vomiting during the third trimester (...) of pregnancy. She was intubated and rapidly developed high anion gap metabolic acidosis. We diagnosed the patient with starvation ketoacidosis based on vomiting with concomitant periods of stress during pregnancy and the absence of other causes of high anion gap metabolic acidosis. She responded poorly to standard treatment, although the ketoacidosis and asthma promptly resolved after an emergency caesarean section. The patient and her baby were safely discharged.Short-term starvation, if it occurs during

2016 Medicine PubMed

7. ABCD position statement on the risk of diabetic ketoacidosis with the use of sodium-glucose cotransporter-2 inhibitors

phosphate in the dog as affected by glucose and phlorizin. Am J Physiol. 1956;184:91-96. 33. Cahill GF, Jr. Fuel metabolism in starvation. Annu Rev Nutr. 2006;26:1-22. 34. Burge MR, Garcia N, Qualls CR, et al. Differential effects of fasting and dehydration in the pathogenesis of diabetic ketoacidosis. Metabolism. 2001;50:171-177. 35. Peters AL, Buschur EO, Buse JB, et al. Euglycemic diabetic ketoacidosis: a potential complication of treatment with sodium-glucose cotransporter 2 inhibition. Diabetes (...) ABCD position statement on the risk of diabetic ketoacidosis with the use of sodium-glucose cotransporter-2 inhibitors Date of preparation 18.11.2016 Association of British Clinical Diabetologists (ABCD) position statement on the risk of diabetic ketoacidosis associated with the use of sodium-glucose cotransporter-2 inhibitors Umesh Dashora 1 , Alison Gallagher 2 , Ketan Dhatariya 3 , Peter Winocour 4 and Rob Gregory 2 on behalf of the ABCD 1 Conquest Hospital, Hastings, UK 2 University

2016 Association of British Clinical Diabetologists

8. Starvation Ketosis: A Rare Cause of Metabolic Acidosis

to protest with non-violence. In the western countries, starvation ketosis or ketoacidosis has been reported in individuals with strict dieting (e.g. or Atkins diet), extreme exercise, and rarely with malnutrition. Few cases of starvation-induced ketoacidosis during and , and during the have also been reported in literature. I saw a young non-verbal woman with quadriplegia who was admitted from a nursing home with a two-day history of worsening abdominal pain and leakage around her percutaneous (...) , drug-induced ketoacidosis, ingestion of toxic alcohols, uremia, and acute kidney injury), we concluded starvation ketosis was the cause of HAGMA due to elevated urinary ketone levels. In clinical practice, fasting or starvation is seldom suspected to be the cause of significant Ketone bodies, which are water-soluble, fat derived fuel are produced by the liver during the time of glucose deficiency . These ketone bodies are used by body tissues for energy generation, when there is limited glucose

2018 Renal Fellow Network

9. Severe ketoacidosis in a patient with spinal muscular atrophy (Full text)

bicarbonate infusion. Given the severity of the ketosis that seemed inconsistent with moderate starvation alone, we postulate that there must have been other contributing factors besides moderate starvation that might explain the severity of acidosis in this particular patient. These factors include low muscle mass, disturbed fatty acid metabolism, hormonal imbalances and defective glucose metabolism. Ketoacidosis is an under-recognized entity in patients with neuromuscular diseases and requires a high (...) Severe ketoacidosis in a patient with spinal muscular atrophy Spinal muscular atrophy (SMA) is a genetic neuromuscular disease characterized by progressive muscle weakness and atrophy. We report a case of a 36-year-old man with SMA type 3 who presented to our emergency department with epigastric pain and vomiting. He was found to have severe ketoacidosis on laboratory evaluation. The patient's symptoms and ketoacidosis resolved after dextrose infusion and a relatively small amount of sodium

2018 CEN Case Reports PubMed

10. Two Bag System for Diabetic Ketoacidosis

: No Criteria Inclusion Criteria: Diagnosis of diabetic ketoacidosis defined as: Blood sugar greater than 250 mg/dl Venous pH less than 7.25 Bicarbonate less than 18 Evidence of ketone formation with either positive urine ketones or elevated beta-hydroxybutyrate > 3 Anion gap greater than 10 +/ - 2 (or higher than expected anion gap corrected for albumin) 18-85 years of age Exclusion Criteria: Pregnancy Hyperglycemic hyperosmolar state Ketosis from other etiology such as starvation or alcoholic ketosis (...) Two Bag System for Diabetic Ketoacidosis Two Bag System for Diabetic Ketoacidosis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Two Bag System for Diabetic Ketoacidosis (2BagDKA) The safety and scientific

2018 Clinical Trials

11. Newer Perspectives of Mechanisms for Euglycemic Diabetic Ketoacidosis (Full text)

is more common than we used to believe. The SGLT-2 inhibitor-associated EDKA also indicates a necessary review of our previous understanding of "diabetic" ketoacidosis, since the SGLT-2 inhibitor predisposes patients to DKA in a "starvation" way. Actually, there are growing reports about starvation-induced ketoacidosis as well. The previously "exclusive" nomenclature and cognition of these entities need to be reexamined. That the hormonal interactions in DKA may differ from the severity of insulin (...) Newer Perspectives of Mechanisms for Euglycemic Diabetic Ketoacidosis Euglycemic diabetic ketoacidosis (EDKA) was considered a rare condition with its specific definition and precipitating factors. However, with the wide use of sodium glucose cotransporter 2 (SGLT-2) inhibitors, the newest class of antidiabetic agents, EDKA has come back into the spotlight. Relevant cases are increasingly being reported along with insights into the mechanism of EDKA. It seems increasingly clear that EDKA

2018 International journal of endocrinology PubMed

12. Ketogenic diet versus ketoacidosis: what determines the influence of ketone bodies on neurons? (Full text)

Ketogenic diet versus ketoacidosis: what determines the influence of ketone bodies on neurons? Glucose is the main energy substrate for neurons, however, at certain conditions, e.g. in starvation, these cells could also use ketone bodies. This approach is used in clinical conditions as the ketogenic diet. The ketogenic diet is actually a biochemical model of fasting. It includes replacing carbohydrates by fats in daily meal. Synthesis of ketone bodies β-hydroxubutirate, acetoacetate and acetone (...) begins once glycogen stores have depleted in the liver. The ketogenic diet can be used to treat clinical conditions, primarily epilepsy. The mechanism of neuroprotective action of ketogenic diet is not very clear. It is shown that ketone bodies influence neurons at three different levels, namely, metabolic, signaling and epigenetic levels. Ketone bodies are not always neuroprotective. Sometimes they can be toxic for the brain. Ketoacidosis which is a very dangerous complication of diabetes mellitus

2018 Neural Regeneration Research PubMed

13. Euglycaemic ketoacidosis in a non-diabetic primigravida following an appendicectomy (Full text)

glucose level would be less than that of a non-pregnant state and in contrast plasma ketones and free fatty acids levels are elevated, resulting in a state of accelerated starvation. These metabolic alterations place a pregnant woman at a higher risk of developing euglycaemic ketoacidosis when allowed to fast for prolonged periods due to medical, surgical and psychological reasons. We report a rare case of euglycaemic ketoacidosis causing severe increased anion gap metabolic acidosis in a non-diabetic (...) Euglycaemic ketoacidosis in a non-diabetic primigravida following an appendicectomy Pregnancy creates significant alterations in energy metabolism which itself is a physiological adaptation to provide continuous flow of energy metabolites to the foetus. The state of insulin resistance created by hormonal changes in pregnancy enables free flow of glucose to the foetus and allows its absorption through facilitated diffusion. As glucose is preferentially available for the foetus, maternal fasting

2017 SAGE Open Medical Case Reports PubMed

14. A rare cause of metabolic acidosis: ketoacidosis in a non-diabetic lactating woman (Full text)

A rare cause of metabolic acidosis: ketoacidosis in a non-diabetic lactating woman Ketoacidosis occurring during lactation has been described infrequently. The condition is incompletely understood, but it appears to be associated with a combination of increased metabolic demands during lactation, reduction in carbohydrate intake and acute illness. We present a case of a 27-year-old woman, 8 weeks post-partum, who was exclusively breastfeeding her child whilst following a low carbohydrate diet (...) . She developed gastroenteritis and was unable to tolerate an oral diet for several days. She presented with severe metabolic acidosis on admission with a blood 3-hydroxybutyrate of 5.4 mmol/L. She was treated with intravenous dextrose and intravenous sodium bicarbonate, and given dietary advice to increase her carbohydrate intake. She made a rapid and full recovery. We provide a summary of the common causes of ketoacidosis and compare our case with other presentations of lactation

2017 Endocrinology, diabetes & metabolism case reports PubMed

15. Euglycemic diabetic ketoacidosis: a diagnostic and therapeutic dilemma (Full text)

admitted with a diagnosis of EDKA. The first patient had insulin pump failure and the second patient had urinary tract infection and nausea, thereby resulting in starvation. Both of them were aggressively treated with intravenous fluids and insulin drip as per the protocol for the blood glucose levels till the anion gap normalized, and the metabolic acidosis reversed. This case series summarizes, in brief, the etiology, pathophysiology and treatment of EDKA.Euglycemic diabetic ketoacidosis (...) Euglycemic diabetic ketoacidosis: a diagnostic and therapeutic dilemma Euglycemic diabetic ketoacidosis (EDKA) is a clinical triad comprising increased anion gap metabolic acidosis, ketonemia or ketonuria and normal blood glucose levels <200 mg/dL. This condition is a diagnostic challenge as euglycemia masquerades the underlying diabetic ketoacidosis. Thus, a high clinical suspicion is warranted, and other diagnosis ruled out. Here, we present two patients on regular insulin treatment who were

2017 Endocrinology, diabetes & metabolism case reports PubMed

16. Ketoacidosis due to a Low-carbohydrate Diet in an Elderly Woman with Dementia and Abnormal Eating Behavior (Full text)

with intravenous fluids followed by oral intake of a regular diet. She remained relapse-free after correcting her eating habits. Healthcare providers should know that abnormal eating behavior in demented people can lead to an extremely-low-carbohydrate diet and cause atypical ketoacidosis unexplained by diabetes, heavy alcohol intake, or starvation conditions. (...) Ketoacidosis due to a Low-carbohydrate Diet in an Elderly Woman with Dementia and Abnormal Eating Behavior Strict restriction of carbohydrates can induce symptomatic ketoacidosis. We herein report a 76-year-old demented woman who developed ketoacidosis after 1 month of abnormal eating behavior involving selectively eating hamburger steak (estimated carbohydrate =12.7 g/day). Laboratory tests showed high-anion-gap metabolic acidosis with elevated blood ketone levels. She was successfully treated

2017 Internal Medicine PubMed

17. Combined metformin-associated lactic acidosis and euglycemic ketoacidosis (Full text)

highlights the parallel occurrence of MALA and euglycemic ketoacidosis, the latter exceeding ketosis due to starvation, suggesting a metformin-triggered inhibition of gluconeogenesis. Affected patients benefit from glucose infusion counteracting suppressed hepatic gluconeogenesis. (...) Combined metformin-associated lactic acidosis and euglycemic ketoacidosis In renal failure metformin can lead to lactic acidosis. Additional inhibition of hepatic gluconeogenesis by accumulation of the drug may aggravate fasting-induced ketoacidosis. We report the occurrence of metformin-associated lactic acidosis (MALA) with concurrent euglycemic ketoacidosis (MALKA) in three patients with renal failure.Patient 1: a 78-year-old woman (pH = 6.89, lactic acid 22 mmol/l, serum ketoacids 7.4 mmol

2017 Wiener klinische Wochenschrift PubMed

18. The DKA that wasn't: a case of euglycemic diabetic ketoacidosis due to empagliflozin (Full text)

of ketoacidosis among patients who take SGLT-2 inhibitors include decrease carbohydrate intake/starvation, acute illness and decrease in insulin dose. When identified, immediate cessation of the medication and administration of glucose must be done, and in some instances, starting an insulin drip might be necessary. We present a case of a patient with diabetes mellitus being on empagliflozin (SGLT-2 antagonist) who was admitted for acute cholecystitis. The hospital course was complicated by euglycemic (...) The DKA that wasn't: a case of euglycemic diabetic ketoacidosis due to empagliflozin Sodium glucose co-transporter (SGLT-2) inhibitor is a relatively new medication used to treat diabetes. At present, the Food and Drug Administration (FDA) has only approved three medications (canagliflozin, dapagliflozin and empagliflozin) in this drug class for the management of Type 2 diabetes. In May 2015, the FDA issued a warning of ketoacidosis with use of this drug class. Risk factors for the development

2016 Oxford Medical Case Reports PubMed

19. Euglycemic Diabetic Ketoacidosis in a Patient with Cocaine Intoxication (Full text)

Euglycemic Diabetic Ketoacidosis in a Patient with Cocaine Intoxication Diabetic ketoacidosis (DKA) is characterized by elevated anion gap metabolic acidosis, hyperglycemia, and elevated ketones in urine and blood. Hyperglycemia is a key component of DKA; however, a subset of DKA patients can present with near-normal blood glucose, an entity described as "euglycemic DKA." This rare phenomenon is thought to be due to starvation and food restriction in insulin dependent diabetic patients. Cocaine (...) diabetes, noncompliance to insulin, and cocaine abuse leading to DKA, with starvation physiology causing development of euglycemic DKA.

2016 Case reports in critical care PubMed

20. Alcoholic ketoacidosis: case report and review

Alcoholic ketoacidosis: case report and review Alcoholic ketoacidosis: case report and review » The Poison Review Alcoholic ketoacidosis: case report and review October 12, 2016, 3:45 pm A Patient with Alcoholic Ketoacidosis and Profound Lactemia. Gerrity RS et al. J Emerg Med 2016 Oct;51:447-449. This is a very good short case-based review of alcoholic ketoacidosis (AKA), and well-worth the 5 – 10 minutes reading time. Some key points: Development of AKA requires increased (binge) alcohol (...) intake along with starvation (decreased food and water intake.) The characteristic high anion gap metabolic acidosis with elevated lactate and β-hydroxybutyrate levels are the result of dehydration, decreased glycogen stores, increased reducing potential (increased NADH) and release of stress hormones (catecholamines, glucagon, cortisol, and growth hormone.) The critical steps in treating AKA include fluid repletion along with administration of dextrose and parenteral thiamine, followed by feeding

2016 The Poison Review blog

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>