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Staphylococcal Scalded Skin Syndrome

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2. The spectrum of Staphylococcal scalded skin syndrome: a case series in children. (PubMed)

The spectrum of Staphylococcal scalded skin syndrome: a case series in children. Staphylococcal scalded skin syndrome (SSSS) is a disease caused by certain toxigenic strains of Staphylococcus aureus. While the classic severe phenotype is widely recognized in children, SSSS in fact exists on a spectrum with mild and moderate variants. Misunderstanding the phenotypic spectrum of SSSS may result in misdiagnosis of an otherwise treatable condition. To increase awareness of the heterogeneity of SSSS

2019 Clinical & Experimental Dermatology

3. Staphylococcal scalded skin syndrome: A pediatric dermatology case report (PubMed)

Staphylococcal scalded skin syndrome: A pediatric dermatology case report Staphylococcal scalded skin syndrome is a condition which predominantly affects children and causes a spectrum of skin lesions. We present a case of a 2-month-old infant with complaints of fever and fragile blisters over the body. The mucosal areas were spared. The diagnosis of staphylococcal scalded skin syndrome was reached on clinical grounds and culture report. The patient responded well to the treatment, which (...) included an antibiotic (cloxacillin), an analgesic (paracetamol), and hydration with intravenous fluids. He was discharged after 8 days, with almost complete resolution of his skin lesions. Having a high clinical suspicion for staphylococcal scalded skin syndrome, early diagnosis/treatment, and following robust hygiene measures are imperative for the effective management of staphylococcal scalded skin syndrome. More efforts are needed to develop novel therapies for staphylococcal scalded skin syndrome.

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2018 SAGE Open Medical Case Reports

4. Staphylococcal scalded skin syndrome in a 4-year-old child: a case report (PubMed)

Staphylococcal scalded skin syndrome in a 4-year-old child: a case report Staphylococcal scalded skin syndrome is an exfoliating skin disease which primarily affects children. Differential diagnosis includes toxic epidermal necrolysis, staphylococcal scalded skin syndrome, epidermolysis bullosa, and Stevens-Johnson syndrome. Staphylococcal scalded skin syndrome primarily affects children and can cause serious morbidity.In this case report we highlight the case of a 4-year-old Caucasian boy (...) . Diagnostic and therapeutic challenges are discussed. Differential diagnoses are considered and therapy is described and discussed. The latest treatment options are used and described. Successful results are achieved in this case due to timely and correct management.Some therapeutic options are widely used without thorough research bases. This case report highlights staphylococcal scalded skin syndrome and its treatment, and future challenges. Further research is warranted and this case report aims

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2018 Journal of medical case reports

5. Emergence of staphylococcal scalded skin syndrome associated with a new toxinogenic, methicillin-susceptible Staphylococcus aureus clone. (PubMed)

Emergence of staphylococcal scalded skin syndrome associated with a new toxinogenic, methicillin-susceptible Staphylococcus aureus clone. A sharp increase in staphylococcal scalded skin syndrome (SSSS) cases has been recorded in our settings since 2015, with 31 cases having been documented during the period 2014-2017. The molecular investigation of strains from the above period showed the emergence of a methicillin-susceptible, mupirocin- and fusidic acid-resistant Staphyloccocus aureus clone

2018 Journal of Medical Microbiology

6. Epidemiology of Staphylococcal Scalded Skin Syndrome in United States Children. (PubMed)

Epidemiology of Staphylococcal Scalded Skin Syndrome in United States Children. Staphylococcal scalded skin syndrome (SSSS) is a blistering dermatosis caused by exfoliative toxins released from Staphylococcus aureus.To describe the incidence, costs, length of stay (LOS), comorbidities and mortality of SSSS in U.S. children.The Nationwide Inpatient Sample 2008-2012 was analysed, including a 20% sample of U.S. hospitalizations and 589 cases of SSSS.The mean annual incidence of SSSS was 7·67

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2017 British Journal of Dermatology

7. Rapid containment of nosocomial transmission of a rare community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) clone, responsible for the Staphylococcal Scalded Skin Syndrome (SSSS) (PubMed)

Rapid containment of nosocomial transmission of a rare community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) clone, responsible for the Staphylococcal Scalded Skin Syndrome (SSSS) The aims of this study were to identify the source and the transmission pathway for a Staphylococcal Scalded Skin Syndrome (SSSS) outbreak in a maternity setting in Italy over 2 months, during 2014; to implement appropriate control measures in order to prevent the epidemic spread within

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2017 Italian journal of pediatrics

8. Recurrent Staphylococcal Scalded Skin Syndrome in an Extremely Low-Birth-Weight Neonate (PubMed)

Recurrent Staphylococcal Scalded Skin Syndrome in an Extremely Low-Birth-Weight Neonate Staphylococcal scalded skin syndrome (SSSS) in premature infants is a rare condition. We present SSSS in an extremely low-birth-weight (ELBW) infant with recurrent and confirmed bacterial sepsis. We present it to emphasize the importance for clinicians to not only recognize the clinical manifestations of SSSS, but also the need to closely monitor infants, especially very low-birth-weight (VLBW) and ELBW

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2017 AJP Reports

9. Severe case of staphylococcal scalded skin syndrome in a 5‐year‐old child – case report (PubMed)

Severe case of staphylococcal scalded skin syndrome in a 5‐year‐old child – case report Benign impetigo can progress into a potential fatal staphylococcal scalded skin syndrome (SSSS) if prompt diagnosis and correct therapy is not established rapidly. Local and systematic antibiotics as well as Lactulose are crucial in order to stop SSSS from progressing. Burns units should be involved when skin lesions are extensive.

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2016 Clinical Case Reports

10. Staphylococcal Scalded Skin Syndrome

Staphylococcal Scalded Skin Syndrome Staphylococcal Scalded Skin Syndrome Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 (...) Staphylococcal Scalded Skin Syndrome Staphylococcal Scalded Skin Syndrome Aka: Staphylococcal Scalded Skin Syndrome , Staphylococcus Scalded Skin Syndrome , Ritters Disease From Related Chapters II. Pathophysiology Hematologic dissemination of from an infectious source (e.g. , URI) Contrast with , where localized infection spreads contiguously strains that carry exfoliative toxins A and B (only 5% of S. aureus strains) Breaks down desmoglein-1 resulting in (breakage of cell to cell adhesions) Similar

2018 FP Notebook

11. Staphylococcal Scalded Skin Syndrome in Child. A Case Report and a Review from Literature (PubMed)

Staphylococcal Scalded Skin Syndrome in Child. A Case Report and a Review from Literature Staphylococcal scalded skin syndrome (SSSS) is the medical term used to define a skin condition induced by the exfoliative toxins produced by Staphylococcus aureus. The disorder is also known as Ritter disease, bullous impetigo, neonatal pemphigus, or staphylococcal scarlet fever. The disease especially affects infants and small children, but has also been described in adults. Prompt therapy with proper (...) associated with fever and impaired general status. Based on clinical and paraclinical examinations a diagnosis of Staphylococcal scalded skin syndrome was established which responded favourably to antibiotic treatment, hydro-electrolytic re-equilibration, and adequate local hygiene. Staphylococcal infection can represent a problem of significant pathological importance sometimes requiring a multidisciplinary approach involving paediatricians, dermatologists, infectious diseases specialists, and plastic

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2016 The Journal of Critical Care Medicine

12. A Systemic Review on Staphylococcal Scalded Skin Syndrome (SSSS): A Rare and Critical Disease of Neonates (PubMed)

A Systemic Review on Staphylococcal Scalded Skin Syndrome (SSSS): A Rare and Critical Disease of Neonates The symptoms of Staphylococcal scalded skin syndrome (SSSS) include blistering of skin on superficial layers due to the exfoliative toxins released from Staphylococcus aureus. After the acute exfoliation of skin surface, erythematous cellulitis occurs. The SSSS may be confined to few blisters localized to the infection site and spread to severe exfoliation affecting complete body (...) . The specific antibodies to exotoxins and increased clearence of exotoxins decrease the frequency of SSSS in adults. Immediate medication with parenteral anti-staphylococcal antibiotics is mandatory. Mostly, SSSS are resistant to penicillin. Penicillinase resistant synthetic penicillins such as Nafcillin or Oxacillin are prescribed as emergency treatment medicine. If Methicillin-resistant Staphylococcus aureus (MRSA) is suspected), antibiotics with MRSA coverage (e.g., Vancomycin or Linezolid) are indicated

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2016 The open microbiology journal

13. Staphylococcal Scalded Skin Syndrome

Staphylococcal Scalded Skin Syndrome Staphylococcal Scalded Skin Syndrome Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 (...) Staphylococcal Scalded Skin Syndrome Staphylococcal Scalded Skin Syndrome Aka: Staphylococcal Scalded Skin Syndrome , Staphylococcus Scalded Skin Syndrome , Ritters Disease From Related Chapters II. Pathophysiology Hematologic dissemination of from an infectious source (e.g. , URI) Contrast with , where localized infection spreads contiguously strains that carry exfoliative toxins A and B (only 5% of S. aureus strains) Breaks down desmoglein-1 resulting in (breakage of cell to cell adhesions) Similar

2016 FP Notebook

14. Staphylococcal Scalded Skin Syndrome in Neonate (PubMed)

Staphylococcal Scalded Skin Syndrome in Neonate We described a case of Staphylococcal Scalded Skin Syndrome in infant age of 21 days by discussing clinical and management issues. This newborn presented large erythematous, eroded, and oozing areas covered by epidermal skin flap. The average surface of cutaneous unsticking on admission was 31.35% of body surface area corresponding to lesions of superficial second-degree burns. An important biological inflammatory syndrome including positive C (...) -reactive protein was found. Under treatment, erythroderma decreased within 7 to 10 days and the newborn was completely healed after 3 weeks of followup, with the disappearance of the inflammatory syndrome and total body surface restored. This clinical case report showed that SSSS remains a major dermatological problem in neonates. Therefore, its diagnosis should be made without doubt and its care should start earlier in a neonate emergency unit in order to have good prognosis. And the rigorous "search

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2015 Case reports in dermatological medicine

15. Adult Staphylococcal Scalded Skin Syndrome Successfully Treated with Plasma Exchange. (PubMed)

Adult Staphylococcal Scalded Skin Syndrome Successfully Treated with Plasma Exchange. 25519855 2016 01 27 2015 04 29 1651-2057 95 5 2015 May Acta dermato-venereologica Acta Derm. Venereol. Adult staphylococcal scalded skin syndrome successfully treated with plasma exchange. 612-3 10.2340/00015555-2033 Kato Takeshi T Department of Dermatology, Shiga University of Medical Science, Setatsukinowa, Otsu, Shiga 520-2192, Japan. Fujimoto Noriki N Nakanishi Gen G Tsujita Yasuyuki Y Matsumura Kazuhiro K (...) Eguchi Yutaka Y Tanaka Toshihiro T eng Case Reports Journal Article Review Sweden Acta Derm Venereol 0370310 0001-5555 IM Aged Follow-Up Studies Humans Male Methicillin-Resistant Staphylococcus aureus isolation & purification Plasma Exchange methods Rare Diseases Risk Assessment Severity of Illness Index Staphylococcal Scalded Skin Syndrome diagnosis drug therapy Treatment Outcome 2014 12 19 6 0 2014 12 19 6 0 2016 1 28 6 0 ppublish 25519855 10.2340/00015555-2033

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2014 Acta Dermato-Venereologica

16. Staphylococcal scalded skin syndrome: diagnosis and management in children and adults. (PubMed)

Staphylococcal scalded skin syndrome: diagnosis and management in children and adults. Staphylococcal scalded skin syndrome is a potentially life-threatening disorder caused most often by a phage group II Staphylococcus aureus infection. Staphylococcal scalded skin syndrome is more common in newborns than in adults. Staphylococcal scalded skin syndrome tends to appear abruptly with diffuse erythema and fever. The diagnosis can be confirmed by a skin biopsy specimen, which can be expedited (...) by frozen section processing, as staphylococcal scalded skin syndrome should be distinguished from life threatening toxic epidermal necrolysis. Histologically, the superficial epidermis is detached, the separation level being at the granular layer. The diffuse skin loss is due to a circulating bacterial exotoxin. The aetiological exfoliating toxin is a serine protease that splits only desmoglein 1. The exfoliative toxins are spread haematogenously from a localized source of infection, causing widespread

2014 Journal of the European Academy of Dermatology and Venereology

17. Staphylococcal Scalded Skin Syndrome (Diagnosis)

Staphylococcal Scalded Skin Syndrome (Diagnosis) Dermatologic Manifestations of Staphylococcal Scalded Skin Syndrome: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA1MzMyNS1vdmVydmlldw== processing > Dermatologic Manifestations of Staphylococcal Scalded Skin Syndrome Updated: Apr 25, 2017 Author: Elizabeth J Usedom, MD, MS; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Dermatologic Manifestations of Staphylococcal Scalded Skin Syndrome Overview Background Staphylococcal scalded skin syndrome (SSSS) is a toxin-mediated exfoliative dermatitis. Toxin-mediated staphylococcal syndromes comprise a group of blistering skin diseases, ranging

2014 eMedicine.com

18. Staphylococcal Scalded Skin Syndrome (Treatment)

Staphylococcal Scalded Skin Syndrome (Treatment) Dermatologic Manifestations of Staphylococcal Scalded Skin Syndrome Treatment & Management: Medical Care, Consultations, Diet Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA1MzMyNS10cmVhdG1lbnQ= processing > Dermatologic Manifestations of Staphylococcal Scalded Skin Syndrome Treatment & Management Updated: Apr 25, 2017 Author: Elizabeth J Usedom, MD, MS; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Dermatologic Manifestations of Staphylococcal Scalded Skin Syndrome Treatment Medical Care Direct the therapy for staphylococcal scalded skin syndrome (SSSS) at eradication of the staphylococcal focus of infection, which generally requires intravenous

2014 eMedicine.com

19. Staphylococcal Scalded Skin Syndrome (Overview)

Staphylococcal Scalded Skin Syndrome (Overview) Dermatologic Manifestations of Staphylococcal Scalded Skin Syndrome: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA1MzMyNS1vdmVydmlldw== processing > Dermatologic Manifestations of Staphylococcal Scalded Skin Syndrome Updated: Apr 25, 2017 Author: Elizabeth J Usedom, MD, MS; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Dermatologic Manifestations of Staphylococcal Scalded Skin Syndrome Overview Background Staphylococcal scalded skin syndrome (SSSS) is a toxin-mediated exfoliative dermatitis. Toxin-mediated staphylococcal syndromes comprise a group of blistering skin diseases, ranging

2014 eMedicine.com

20. Staphylococcal Scalded Skin Syndrome (Follow-up)

Staphylococcal Scalded Skin Syndrome (Follow-up) Dermatologic Manifestations of Staphylococcal Scalded Skin Syndrome Treatment & Management: Medical Care, Consultations, Diet Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA1MzMyNS10cmVhdG1lbnQ= processing > Dermatologic Manifestations of Staphylococcal Scalded Skin Syndrome Treatment & Management Updated: Apr 25, 2017 Author: Elizabeth J Usedom, MD, MS; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Dermatologic Manifestations of Staphylococcal Scalded Skin Syndrome Treatment Medical Care Direct the therapy for staphylococcal scalded skin syndrome (SSSS) at eradication of the staphylococcal focus of infection, which generally requires intravenous

2014 eMedicine.com

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