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1681. The time course for changes in plasma [h+] after sodium bicarbonate ingestion. (PubMed)

The time course for changes in plasma [h+] after sodium bicarbonate ingestion. 19168932 2009 04 03 2013 11 21 1555-0265 2 3 2007 Sep International journal of sports physiology and performance Int J Sports Physiol Perform The time course for changes in plasma [h+] after sodium bicarbonate ingestion. 323-6 Renfree Andrew A School of Sport and Exercise Science, University of Worcester, Henwick Grove, UK. eng Clinical Trial Journal Article Randomized Controlled Trial United States Int J Sports (...) Physiol Perform 101276430 1555-0265 8MDF5V39QO Sodium Bicarbonate H0G9379FGK Calcium Carbonate IM Adult Analysis of Variance Bicycling physiology Calcium Carbonate blood metabolism Dietary Supplements Double-Blind Method Exercise physiology Exercise Tolerance drug effects Female Humans Male Muscle, Skeletal drug effects physiology Sodium Bicarbonate blood metabolism Time Factors 2009 1 27 9 0 2007 9 1 0 0 2009 4 4 9 0 ppublish 19168932

2009 International journal of sports physiology and performance

1682. TREAD-20 Extension

of osteoarthritis of at least one knee: Diagnosed according to ACR criteria. Based upon a knee X-ray performed within 6 months prior to Screening, the radiograms must be classified as a Grade II or III for osteoarthritis of the knee according to the Kellgren & Lawrence grading system based upon a radiologist's written report or individual certified for reading knee radiograms. (Sharpening of the tibial spine is not considered to be an osteophyte). Patients with symptoms consistent with osteoarthritis (...) will select the more painful knee and the contralateral knee must have a VAS pain score of < 30 mm. Patients must have had knee pain in the signal knee on at least 50% of the days in the month preceding Screening. Patients who are able to complete efficacy measurement questionnaires and can understand and read English or Spanish (Spanish forms will be provided). Patients who can perform the 50-foot walk test without the support of crutches or other assistive devices, except for canes. If patient uses

2009 Clinical Trials

1683. Effect of Glucosamine or Ibuprofen Combined With Physical Training in Patients With Knee-Osteoarthritis

of Sports Medicine Copenhagen, Bispebjerg Hospital, Denmark ClinicalTrials.gov Identifier: Other Study ID Numbers: HIM-037 KF-01-18904 First Posted: January 30, 2009 Last Update Posted: January 30, 2009 Last Verified: January 2009 Keywords provided by Bispebjerg Hospital: Knee Osteoarthritis exercise strength training Glucosamine Dietary supplement Ibuprofen NSAID Additional relevant MeSH terms: Layout table for MeSH terms Osteoarthritis Osteoarthritis, Knee Arthritis Joint Diseases Musculoskeletal (...) : Glucosamine Drug: glucosamine sulphate Subjects are administered glucosamine-sulphate tablets of 500 mg * 3 daily, while they are performing a strength-training program with both legs (*3 weekly) for 12 weeks. Other Name: glucosamine from Ferrosan Experimental: Ibuprofen Drug: ibuprofen Subjects are administered 600 mg * 2 daily, while they are performing a strength-training program with both legs (*3 weekly) for 12 weeks Other Name: "Ibumetin" from Nycomed (vnr:38 83 71) Placebo Comparator: Placebo Drug

2009 Clinical Trials

1684. Multi-Center Study Evaluating the Efficacy of Wobenzym(R)N in Treating Knee Osteoarthritis

Information provided by: Atrium Innovations Study Details Study Description Go to Brief Summary: The objective of this study is to determine the most effective dose of Wobenzym® N versus placebo at reducing pain severity as measured by the WOMAC pain score in subjects with symptomatic knee osteoarthritis (OA) at 6 weeks of treatment. Condition or disease Intervention/treatment Phase Knee Osteoarthritis Dietary Supplement: Wobenzym® N Dietary Supplement: Placebo Phase 2 Phase 3 Detailed Description (...) to rheumatoid arthritis, sprains and strains, reduction of C-reactive protein, sports injuries and joint and muscular pain, as well as OA of the knee. Several comparative studies conducted with Phlogenzym®, an oral enzyme-rutin combination containing bromelain 90 mg, trypsin 48 mg and rutin 100 mg, have proved the product to be effective and safe in the treatment of OA as compared to NSAIDs. [For review, see Leipner, et al. Biodrugs 2001;15(12):779-89.] Study Design Go to Layout table for study information

2009 Clinical Trials

1685. Vegetable Consumption in Relation to Health

. Dietary Supplement: Vegetables 200 or 50 grams of vegetables daily for four weeks Active Comparator: Weight loss interventio Consumption of - 1000 kcal daily, for four weeks to be used as a positive control for the vegetables interventions. Dietary Supplement: energy restriction Consume about 1000 kcal less daily, for four weeks, as a positive control to the vegetables interventions. Outcome Measures Go to Primary Outcome Measures : Investigate whether the maximal exercise performance test is a good (...) and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00959790 Recruitment Status : Completed First Posted : August 17, 2009 Last Update Posted : February 28, 2012 Sponsor: TNO Collaborator: Netherlands: Ministry of Health, Welfare and Sports Information provided by (Responsible Party): W.J. Pasman, TNO Study Details Study

2009 Clinical Trials

1686. Blue-Green Algae

, Kabore F, Zongo F, et al. Nutrition rehabilitation of undernourished children utilizing Spiruline and Misola. Nutr J 2006;5:3. . Baicus C, Baicus A. Spirulina did not ameliorate idiopathic chronic fatigue in four N-of-1 randomized controlled trials.Phytother Res 2007;21:570-3. . Kalafati M, Jamurtas AZ, Nikolaidis MG, et al. Ergogenic and antioxidant effects of spirulina supplementation in humans. Med Sci Sports Exerc 2010;42:142-51. . Baicus C, Tanasescu C. Chronic viral hepatitis, the treatment (...) Blue-Green Algae Blue-Green Algae: MedlinePlus Supplements The navigation menu has been collapsed. Menu Show Search Search MedlinePlus GO You Are Here: → → → Blue-Green Algae URL of this page: https://medlineplus.gov/druginfo/natural/923.html Blue-Green Algae To use the sharing features on this page, please enable JavaScript. What is it? "Blue-green algae" refers to several species of bacteria that produce blue-green colored pigments. They grow in salt water and some large fresh water lakes

2009 National Centre for Complementary and Alternative Medicine

1687. L-Arginine

Dichloride, L-Arginine HCl, L-Arginine Hexanoate, L-Arginine Hydrochloride, L-Arginine Ketoisocaproic Acid, L-Arginine L-Pyroglutamate, L-Arginine Pyroglutamate, L-Arginine Taurinate, Malate de Di-Arginine, Orotate de Di-Arginine, R-Gene 10. Methodology To learn more about how this article was written, please see the Natural Medicines Comprehensive Database . References Aguiar AF, Balvedi MC, Buzzachera CF, et al. L-Arginine supplementation does not enhance blood flow and muscle performance in healthy (...) and physically active older women. Eur J Nutr. 2016;55:2053-62. . Camarena Pulido EE, García Benavides L, Panduro Barón JG, et al. Efficacy of L-arginine for preventing preeclampsia in high-risk pregnancies: A double-blind, randomized, clinical trial. Hypertens Pregnancy. 2016;35:217-25. . Pahlavani N, Entezari MH, Nasiri M, et al. The effect of l-arginine supplementation on body composition and performance in male athletes: a double-blinded randomized clinical trial. Eur J Clin Nutr. 2017;71:544-548

2009 National Centre for Complementary and Alternative Medicine

1688. Pantothenic Acid (Vitamin B5)

. Strahlenther.Onkol. 2011;187:485-491. . Mets, M. A., Ketzer, S., Blom, C., van Gerven, M. H., van Willigenburg, G. M., Olivier, B., and Verster, J. C. Positive effects of Red Bull(R) Energy Drink on driving performance during prolonged driving. Psychopharmacology (Berl) 2011;214:737-745. . Ivy, J. L., Kammer, L., Ding, Z., Wang, B., Bernard, J. R., Liao, Y. H., and Hwang, J. Improved cycling time-trial performance after ingestion of a caffeine energy drink. Int J Sport Nutr Exerc Metab 2009;19:61-78. . Plesofsky (...) -Vig N. Pantothenic acid. In: Shils ME, Olson JA, Shike M, eds. Modern Nutrition in Health and Disease, 8th ed. Malvern, PA: Lea & Febiger, 1994. Anon. Calcium pantothenate in arthritic conditions. A report from the General Practitioner Research Group. Practitioner 1980;224:208-11. . Webster MJ. Physiological and performance responses to supplementation with thiamin and pantothenic acid derivatives. Eur J Appl Physiol Occup Physiol 1998;77:486-91. . Arnold LE, Christopher J, Huestis RD, Smeltzer DJ

2009 National Centre for Complementary and Alternative Medicine

1689. Phosphate Salts

1;8:591-9. . Brewer CP, Dawson B, Wallman KE, Guelfi KJ. Effect of repeated sodium phosphate loading on cycling time-trial performance and VO2peak. Int J Sport Nutr Exerc Metab. 2013 Apr;23:187-94. . Buck CL, Wallman KE, Dawson B, Guelfi KJ. Sodium phosphate as an ergogenic aid. Sports Med. 2013 Jun;43:425-35. . Buck CL, Dawson B, Guelfi KJ, McNaughton L, Wallman KE. Sodium phosphate supplementation and time trial performance in female cyclists. J Sports Sci Med. 2014 Sep 1;13:469-75. . Brewer CP (...) , Dawson B, Wallman KE, Guelfi KJ. Effect of Sodium Phosphate Supplementation on Cycling Time Trial Performance and VO2 1 and 8 Days Post Loading. J Sports Sci Med. 2014 Sep 1;13:529-34. . West JS, Ayton T, Wallman KE, Guelfi KJ. The effect of 6 days of sodium phosphate supplementation on appetite, energy intake, and aerobic capacity in trained men and women. Int J Sport Nutr Exerc Metab. 2012 Dec;22:422-9. . van Vugt van Pinxteren MW, van Kouwen MC, van Oijen MG, van Achterberg T, Nagengast FM

2009 National Centre for Complementary and Alternative Medicine

1690. Pycnogenol

, and stocking in chronic venous insufficiency. Int J Angiol. 2015 Dec;24:268-74. Epub 2015 Jul 15. . Taxon: Pinus pinaster Aiton. U.S. National Plant Germplasm System. Available at: https://npgsweb.ars-grin.gov/gringlobal/taxonomydetail.aspx?28525. Accessed May 29, 2018. Vinciguerra G, Belcaro G, Bonanni E, et al. Evaluation of the effects of supplementation with Pycnogenol on fitness in normal subjects with the Army Physical Fitness Test and in performances of athletes in the 100-minute triathlon. J Sports (...) M, Belcaro G, Saggino A, Luzzi R, Dugall M, Feragalli B. Pycnogenol supplementation in minimal cognitive dysfunction. J Nuerosurg Sci. 2018 Jun;62:279-284. . Belcaro G, Dugall M, Ippolito E, Hus S, Saggino A, Feragalli B. The COFU3 Study. Improvement in cognitive function, attention, mental performance with Pycnogenol in healthy subjects (55-70) with high oxidative stress. J Neurosurg Sci 2015 Dec;59:437-46. Belcaro G, Dugall M. Preservation of muscular mass and strength in aged subjects

2009 National Centre for Complementary and Alternative Medicine

1691. Chronic Pain

-methionine (SAMe) for knee osteoarthritis pain have had conflicting results. There isn’t enough research on dimethyl sulfoxide (DMSO) or methylsulfonylmethane (MSM) for osteoarthritis pain to allow conclusions to be reached. For more information, see the NCCIH fact sheet on . Rheumatoid arthritis The amount of research on mind and body practices for rheumatoid arthritis pain is too small for conclusions to be reached about their effectiveness. Dietary supplements containing omega-3 fatty acids , gamma (...) of tai chi, yoga, mindfulness, and biofeedback for fibromyalgia symptoms have had promising results, the evidence is too limited to allow definite conclusions to be reached about whether these approaches are helpful. There is insufficient evidence that any natural products can relieve fibromyalgia pain, with the possible exception of vitamin D supplements, which may reduce pain in people with fibromyalgia who have low vitamin D levels. Studies of homeopathy have not demonstrated that it is beneficial

2009 National Centre for Complementary and Alternative Medicine

1692. Ephedra and Ephedrine Alkaloids

ephedra species) in the United States in 2004. It was an ingredient in some dietary supplements marketed for weight loss, increased energy, and enhanced athletic performance. The dried stems and leaves of the ephedra plant have been used to create capsules, tablets, extracts, and teas. How Much Do We Know? A large amount of research led to ephedrine alkaloids becoming main oral asthma medications in the 1940s and 1950s. Ephedra also has been used as a weight-loss agent and energy enhancer for athletic (...) performance. However, the increasing number of reported adverse events caused the FDA to ban dietary supplements that contain ephedrine alkaloids. What Have We Learned? According to the FDA, there is little evidence of ephedra’s effectiveness, except for short-term weight loss. However, the increased risk of heart problems and stroke outweighs any benefits. What Do We Know About Safety? The FDA banned the U.S. sale of dietary supplements containing ephedrine alkaloids. It found that these supplements had

2009 National Centre for Complementary and Alternative Medicine

1693. Children, Alternative Therapies

complementary health approaches vary in age and health status. For example: About 10 percent of infants are given teas or botanical supplements, usually for fussiness or stomach problems. About 40 percent of children aged 2 to 8 are given dietary supplements containing vitamins or minerals. However, that age group generally eats a nutritionally adequate diet. Teens are particularly likely to use products that claim to improve sports performance, increase energy levels, or promote weight loss. Children (...) for Children The 2012 National Health Interview Survey (NHIS) included a comprehensive survey on the use of complementary health approaches by almost 45,000 Americans, including more than 10,000 children aged 4 to 17. The survey found that 11.6 percent of the children had used or been given some form of complementary health product or practice, such as yoga or dietary supplements, during the past year. Data from the found that from 2012 to 2017 the use of yoga and meditation in the past 12 months

2009 National Centre for Complementary and Alternative Medicine

1694. Carnitine

to improve performance. However, twenty years of research finds no consistent evidence that carnitine supplements can improve exercise or physical performance in healthy subjects—at doses ranging from 2–6 grams/day administered for 1 to 28 days [ ]. (The total body content of carnitine is about 20 grams in a man weighing 155 pounds, almost all of it in the skeletal muscle [ ].) For example, carnitine supplements do not appear to increase the body's use of oxygen or improve metabolic status when (...) more and improved their performance on memory-requiring tasks. At present there are no equivalent studies of this kind in humans. However, a meta-analysis of double-blind, placebo-controlled studies suggests that supplements of acetyl-L-carnitine may improve mental function and reduce deterioration in older adults with mild cognitive impairment and Alzheimer's disease [ ]. In these studies, subjects took 1.5–3.0 grams/day of acetyl-L-carnitine for 3–12 months. Cardiovascular and peripheral arterial

2009 National Centre for Complementary and Alternative Medicine

1695. Efficacy of a Tea Catechin Sports Drink for Enhancing Exercise-Induced Fat Loss

Information provided by: Provident Clinical Research Study Details Study Description Go to Brief Summary: The primary objective of this trial is to evaluate the influence of consuming a tea catechin containing sports beverage on body fat mass during exercise-induced weight loss among overweight and obese men and women. Condition or disease Intervention/treatment Overweight Obesity Dietary Supplement: 500 mL/day of a beverage providing approximately 625 mg catechins Other: Control beverage matched (...) by the National Library of Medicine related topics: available for: Groups and Cohorts Go to Group/Cohort Intervention/treatment Active Tea catechin sport beverage Dietary Supplement: 500 mL/day of a beverage providing approximately 625 mg catechins Subjects were asked to consume 500 mL/day of a beverage providing approximately 625 mg catechins Control Control beverage Other: Control beverage matched for energy and caffeine content 500 mL/day of a control beverage Outcome Measures Go to Primary Outcome

2008 Clinical Trials

1696. Muscle Regrowth During Physical Rehabilitation and Amino Acid Supplementation

Muscle Regrowth During Physical Rehabilitation and Amino Acid Supplementation Muscle Regrowth During Physical Rehabilitation and Amino Acid Supplementation - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Muscle Regrowth During Physical Rehabilitation and Amino Acid Supplementation The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00760383 Recruitment Status : Completed First Posted : September 26, 2008 Results First Posted : December 4, 2014 Last Update Posted : December 4, 2014 Sponsor: University

2008 Clinical Trials

1697. Fit in the Aged by Professional Training

validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00783159 Recruitment Status : Completed First Posted : October 31, 2008 Last Update Posted : January 12, 2011 Sponsor: University of Erlangen-Nürnberg Medical School Collaborators: Klinikum Nürnberg Institute of Biomedicine of Aging Institute of Sport Science and Sport Robert Bosch (...) function by physical exercise in prefrail elderly persons. Prefrail participants are recruited according to the frailty score of Fried. Taking into account, that vitamin D supplementation reduces falls and improves muscle strength in older people, all participants are supplemented by vitamin D. Two different training methods are tested. After a run-in period of supplementation of vitamin D for two months, participants will be randomized into three different equally sized groups (n=25): Group

2008 Clinical Trials

1698. The effects of 10 weeks of resistance training combined with beta-alanine supplementation on whole body strength, force production, muscular endurance and body composition. (PubMed)

] brought about through beta-ala supplementation had a positive effect on training responses. Twenty-six Vietnamese sports science students completed the study. The subjects completed a 10-week resistance-training program whilst consuming 6.4 g x day(-1) of beta-ala (beta-ALG) or a matched dose of a placebo (PLG). Subjects were assessed prior to and after training for whole body strength, isokinetic force production, muscular endurance, body composition. beta-Alanine supplemented subjects increased M (...) The effects of 10 weeks of resistance training combined with beta-alanine supplementation on whole body strength, force production, muscular endurance and body composition. Carnosine (Carn) occurs in high concentrations in skeletal muscle is a potent physico-chemical buffer of H+ over the physiological range. Recent research has demonstrated that 6.4 g x day(-1) of beta-alanine (beta-ala) can significantly increase skeletal muscle Carn concentrations (M-[Carn]) whilst the resultant change

2008 Amino acids

1699. Carbohydrate-supplement form and exercise performance. (PubMed)

Carbohydrate-supplement form and exercise performance. Numerous studies have shown that ingesting carbohydrate in the form of a drink can improve exercise performance by maintaining blood glucose levels and sparing endogenous glycogen stores. The effectiveness of carbohydrate gels or jellybeans in improving endurance performance has not been examined. On 4 separate days and 1-2 hr after a standardized meal, 16 male (8; 35.8 +/- 2.5 yr) and female (8; 32.4 +/- 2.4 yr) athletes cycled at 75% VO (...) (2peak) for 80 min followed by a 10-km time trial. Participants consumed isocaloric (0.6 g of carbohydrate per kg per hour) amounts of randomly assigned sports beans, sports drink, gel, or water only, before, during, and after exercise. Blood glucose concentrations were similar at rest between treatments and decreased significantly during exercise with the water trial only. Blood glucose concentrations for all carbohydrate supplements were significantly, p < .05, higher than water during the 80-min

2008 International journal of sport nutrition and exercise metabolism

1700. Caffeine supplementation and multiple sprint running performance. (PubMed)

Caffeine supplementation and multiple sprint running performance. The aim of this study was to examine the effects of caffeine supplementation on multiple sprint running performance.Using a randomized double-blind research design, 21 physically active men ingested a gelatin capsule containing either caffeine (5 mg x kg(-1) body mass) or placebo (maltodextrin) 1 h before completing an indoor multiple sprint running trial (12 x 30 m; repeated at 35-s intervals). Venous blood samples were drawn (...) sprint work requires further investigation, the results of the present study show that caffeine has ergogenic properties with the potential to benefit performance in both single and multiple sprint sports.

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2008 Medicine and science in sports and exercise

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