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Sports Performance Supplement

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1621. Preventing falls and harm from falls in older people - best practice guidelines for Australian hospitals

considerations 115 17.3.1 Cognitive impairment 115 17.3.2 Indigenous and culturally and linguistically diverse groups 115 17.3.3 Climate 115 17.4 Economic evaluation 115 Pagex P r e v e n t i n g F a l l s a n d H a r m F r o m F a l l s i n O l d e r P e o p l e 18 Vitamin D and calcium supplementation 117 18.1 Background and evidence 118 18.1.1 Vitamin D supplementation (with or without calcium) in the community setting 118 18.1.2 Vitamin D combined with calcium s u p p l e m e n t a t i o n i n t h e R (...) A C F s e t t i n g 1 1 9 18.1.3 Vitamin D supplementation alone i n R A C F s e t t i n g s 1 1 9 1 8 . 1 . 4 V i t a m i n D , s u n l i g h t a n d w i n t e r in the community setting 119 18.1.5 Toxicity and dose 120 18.2 Principles of care 120 18.2.1 Assess vitamin D adequacy 120 18.2.2 Ensure minimum sun exposure to prevent vitamin D deficiency 120 18.2.3 Consider vitamin D and calcium supplementation 120 18.2.4 Encourage patients to include foods high in calcium in their diet 120 18.2.5

2009 Clinical Practice Guidelines Portal

1622. Safety of Probiotics to Reduce Risk and Prevent or Treat Disease

reports and technology assessments to assist public- and private-sector organizations in their efforts to improve the quality of health care in the United States. This review was jointly sponsored by the National Institutes of Health (NIH) Office of Dietary Supplements (ODS), the NIH National Center for Complementary and Alternative Medicine (NCCAM), and the Food and Drug Administration (FDA) Center for Food Safety and Applied Nutrition (CFSAN). The reports and assessments provide organizations (...) by providing important information to help improve health care quality. We welcome comments on this evidence report. They may be sent by mail to the Task Order Officer named below at: Agency for Healthcare Research and Quality, 540 Gaither Road, Rockville, MD 20850, or by e-mail to epc@ahrq.gov. Carolyn M. Clancy, M.D. Director Agency for Healthcare Research and Quality Paul Coates, Ph.D. Director Office of Dietary Supplements National Institutes of Health Josephine P. Briggs, M.D. Director National Center

2011 EvidenceUpdates

1623. Recreational football for disease prevention and treatment in untrained men: a narrative review examining cardiovascular health, lipid profile, body composition, muscle strength and functional capacity. Full Text available with Trip Pro

controlled trial, published in the BJSM in January 2009, showed that football increased maximal oxygen uptake and muscle and bone mass, and lowered fat percentage and blood pressure, in untrained men, and since then more than 70 articles about football for health have been published, including publications in two supplements of the Scandinavian Journal of Medicine and Science in Sports in 2010 and 2014, prior to the FIFA World Cup tournaments in South Africa and Brazil. While studies of football training (...) effects have also been performed in women and children, this article reviews the current evidence linking recreational football training with favourable effects in the prevention and treatment of disease in adult men.Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

2015 British Journal of Sports Medicine

1624. Is there any risk in healthy teenage boys wanting to build muscle in taking high protein drinks and are there significant benefits

searched the Cochrane Library, TRIP, Pubmed and NHS Evidence databases but found no studies assessing either the efficacy or adverse effects of bodybuilding supplements in teenagers. We did find one paper published in 2005 on the use of dietary supplements and hormones in adolescents (1) This reports: “Ergogenic aids, such as nutritional supplements, anabolic steroids and human growth hormone, are increasingly being used to enhance sports performance or body image. While few rigorous scientific studies (...) for bodybuilding or performance enhancement in adolescents. Health care professionals need to educate themselves about ergogenic use and ask informed questions of their adolescent patients. An honest discussion of the limitations of most supplements, and acknowledgement that some supplements may work some of the time, may allow the physician to be more credible and useful in providing medical care and guidance to the adolescent seeking to improve body image or athletic performance.” 1. Answered 31 March 2011

2011 TRIP Answers

1625. “I don’t like Cricket, oh no, I…” used it to inspire this blog!

! The added scourge of EIMD includes increased stiffness, swelling, decreased strength and power and altered proprioception. , Left alone, EIMD and DOMS usually resolve clinically after four to five days and athletes can return to pre-EIMD training levels. And here in belies the plight of physios, coaches and athletes alike. Anything less than 100% can be the difference between a performance nonpareil or a seasons work undone. In most sporting events (think Tour de France, Wimbledon [Murray on a good run (...) ], Test Match Cricket [ok, so I’m talking key fast bowlers and batsmen not out for <10 runs over two innings!]), a 5-day wait for a full force flexion of the is 3 to 4 days too long. Strategies to help reduce the effects of DOMS and allow a hastier return to full training or competition are like catnip to the high level sports arena. Massage, nutritional supplements and anti-inflammatory medications have all made the list, ice baths being the latest panacea. The problem with all these strategies

2014 David Nunan's blog

1626. “I don’t like Cricket, oh no, I…” used it to inspire this blog!

! The added scourge of EIMD includes increased stiffness, swelling, decreased strength and power and altered proprioception. , Left alone, EIMD and DOMS usually resolve clinically after four to five days and athletes can return to pre-EIMD training levels. And here in belies the plight of physios, coaches and athletes alike. Anything less than 100% can be the difference between a performance nonpareil or a seasons work undone. In most sporting events (think Tour de France, Wimbledon [Murray on a good run (...) ], Test Match Cricket [ok, so I’m talking key fast bowlers and batsmen not out for <10 runs over two innings!]), a 5-day wait for a full force flexion of the is 3 to 4 days too long. Strategies to help reduce the effects of DOMS and allow a hastier return to full training or competition are like catnip to the high level sports arena. Massage, nutritional supplements and anti-inflammatory medications have all made the list, ice baths being the latest panacea. The problem with all these strategies

2014 David Nunan's blog

1627. UCL’s senior common room and the Boston marathon: emancipation in the 1960s, and now

like her. The reference you gave is to the sponsor’s site. The only bit that I’d disagree with is “well-researched”. There’s very little research when it comes to performance. The charitable interpretation is that it means that sensible, uncontaminated ingredients are used. Diet whey is being used as a convenient source of protein, that’s all. There is no comparison between that and, say, Carol Vorderman’s lyrical endorsement of vitamin supplements for all. (c) The example you produce about coitus (...) , . In 1972 women were allowed to run in Boston, and within 10 years, the women’s record time had fallen by a full hour. Physiology hadn’t changed, but confidence had. Of course it wasn’t until the 2012 Olympics that women gained total equality in sport. Everyone who said that women were incapable of competing in combat sports should see in action. She’s the ultimate high-achiever. She’s an accomplished musician (grade 7 cello, piano) and she played at the Albert Hall with the Reading Youth Orchestra. She

2014 DC's Improbable Science blog

1628. Clinical guidelines for the diagnosis and management of early rheumatoid arthritis

of rheumatoid arthritis 19 Multidisciplinary care and care planning 19 Patient information and education 19 Psychosocial support 20 Sleep patterns and fatigue 21 Pharmacological interventions for RA 22 Simple analgesics (eg. paracetamol) 22 Fatty acid supplements (omega-3 and gamma-linolenic acid) 22 Traditional non-steroidal anti-inflammatory drugs and COX-2 inhibitors 23 Disease modifying antirheumatic drugs 25 Corticosteroids 26 Complementary medicines 27ii Clinical guideline for the diagnosis (...) working within a multidisciplinary team. These include, but are not limited to, physiotherapists, nurses, occupational therapists, sports medicine personnel, podiatrists, dieticians, psychologists, pharmacists and community health workers. The guideline is applicable to primary care settings in metropolitan, regional, rural, and remote areas of Australia. The guideline focuses on the diagnosis and management of adults with early stage RA. The early stage of RA is defined as ‘disease duration of less

2009 The Royal Australian College of General Practitioners

1629. Gait Disorders in the Elderly

, subcortical, or basal ganglia dysfunction. Deviations from path are strong indicators of motor control deficits. Arm swing may be reduced or absent in Parkinson disease and vascular dementias. Arm swing disorders may also be adverse effects of dopamine -blocking drugs (typical and atypical antipsychotics). Evaluation The goal is to determine as many potential contributing factors to gait disorders as possible. A performance-oriented mobility assessment tool may be helpful (see Table: ), as may other (...) clinical tests (eg, a screening cognitive examination for patients with gait problems possibly due to frontal lobe syndromes). Table Performance-Oriented Assessment of Mobility Component Findings Score* Clinical Meaning Initiation of gait (immediately after being told to go) Any hesitancy or multiple attempts to start 0 Parkinson disease Isolated gait initiation failure (stroke or dementia) Frontal gait disorder No hesitancy 1 Right step length and height (right swing foot) Does not pass left stance

2013 Merck Manual (19th Edition)

1630. Dehydroepiandrosterone (DHEA)

of wild yam is not recommended as a supplement as the body is unable to convert the precursors to DHEA. (See also .) Claims DHEA supplements are said to improve mood, energy, sense of well-being, and the ability to function well under stress. They are also said to improve athletic performance, stimulate the immune system, deepen nightly sleep, lower cholesterol levels, decrease body fat, build muscles, reverse aging, improve brain function in patients with Alzheimer disease, increase libido (...) , and decrease symptoms of . Evidence The medicinal claims of DHEA have not been fully supported by the evidence. In addition, DHEA is banned by numerous professional sports organizations as it is classified as a "prohormone." DHEA levels are known to naturally decrease with age and therefore people in search of the unattainable fountain of youth have turned to DHEA supplementation as a possible solution to ailments associated with age. Studies have been reported showing both positive and negative results

2013 Merck Manual (19th Edition)

1631. Creatine

documented. Creatine references : Creatine for treating muscle disorders. Cochrane Database Syst Rev (6):CD004760, 2013. doi: 10.1002/14651858.CD004760.pub4. : Effect of creatine supplementation on body composition and performance: a meta-analysis. Int J Sport Nutr Exerc Metab 13(2):198-226, 2003. : Beneficial effect of creatine supplementation in knee osteoarthritis. Med Sci Sports Exerc 43(8):1538-1543, 2011. doi: 10.1249/MSS.0b013e3182118592. More Information NIH National Center for Complementary (...) physical and athletic performance and to reduce muscle fatigue. Evidence Some evidence suggests creatine is effective at increasing work done in a short maximal effort (eg, sprinting, weightlifting). It has proven therapeutic use in muscle phosphorylase deficiency ( type V [McArdle disease]) and gyrate atrophy of the choroid and retina; early data also suggest possible effects in and . Numerous clinical trials have demonstrated that creatine supplementation is well tolerated and may increase muscle

2013 Merck Manual (19th Edition)

1632. Pharmacologic-based strategies for smoking cessation: clinical and cost-effectiveness analyses

) Vancouver, British Columbia Jed E. Rose, PhD Professor, Duke University Medical Center Durham, North Carolina Authorship Khai Tran, research lead, coordinated the research project; selected studies; extracted, tabulated and analyzed data; and wrote the clinical sections of the report. Keiko Asakawa, lead for the economic section, selected articles; extracted data for the economic review; performed the economic modelling, and population and budget impact analyses; wrote the economic, budget impact (...) that were missed in the search, review of the first draft, and critical review of the final draft. Andrew Pipe participated in the conceptualization of clinical approaches to smoking cessation, preparation and revision of portions of the manuscript addressing clinical considerations and descriptions of smoking-related diseases, and editing and revisions of the final draft. David Kaunelis developed the literature search strategies, performed all searches and search updates, managed report referencing

2010 EvidenceUpdates

1633. The prevalence, variety and impact of wrist problems in elite professional golfers on the European Tour. Full Text available with Trip Pro

professional golfers.European Tour golfers eligible to compete at the 2009 BMW PGA Championship at Wentworth were studied. Study design involved the completion of a structured questionnaire supplemented by interview and examination when required, with performance statistics provided by the European Tour. The severity of injury was assessed by the number of missed tournaments and the amount of time of missed practice.128 of 153 eligible golfers, (84%) completed the study with 38 golfers (30%) reporting 43 (...) The prevalence, variety and impact of wrist problems in elite professional golfers on the European Tour. Golf is a popular sport played by an estimated 57 million people. Previous studies on wrist injuries in elite golfers have been of simple design and have demonstrated such injuries to be frequent, although no studies report the incidence, variety, severity or impact on the activity of wrist injuries in detail. This prospective cross-sectional study assesses these factors in a cohort of elite

2013 British Journal of Sports Medicine

1634. Effects of Caffeine in Hydration and Energy Metabolism

the experimental trial to assure that the same diet and physical activity patterns were maintained. Also it was analyzed if the effect of caffeine was independent of body composition, assessed by dual-energy x-ray absorptiometry. To perform this research study, a total of 30 non-smoker males, low caffeine users (<100 mg/day), aged 20-39 yrs [body mass (BM): 72.7 ± 8.8 kg; Height: 1.77 ± 0.07 m] were followed in a double-blind crossover experimental design with two conditions in a random sequence: caffeine (5 (...) mg per kg of BM/day) and malt-dextrine as placebo, both through capsules. Conditions lasted for 4 days with a 3-day washout period. Evaluations were performed at baseline (visit-1), end of condition 1 (visit-2), and end of condition 2 (visit-3). Fat and fat-free masses (FFM) were assessed by dual energy x-ray absorptiometry. TBW and ECW were determined by dilution techniques (deuterium and bromide, specifically) while ICW was calculated as the difference between TBW and ECW (Schoeller et al

2011 Clinical Trials

1635. Effects of Theobromine and Caffeine on Mood, Cognition and Blood Pressure

Details Study Description Go to Brief Summary: The purpose of this study was to measure potential mood, cognition and blood pressure effects of theobromine and caffeine in healthy women Condition or disease Intervention/treatment Phase Mood Dietary Supplement: theobromine Dietary Supplement: Caffeine Dietary Supplement: caffeine + theobromine Dietary Supplement: placebo Not Applicable Detailed Description: Background Previous research has shown that naturally occurring chocolate ingredients (...) Resource links provided by the National Library of Medicine related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Active Comparator: theobromine theobromine (700 mg) in capsule Dietary Supplement: theobromine 700 mg theobromine in gelatin capsules given one time only Other Name: 3,7-dimethylxanthine Active Comparator: caffeine caffeine (120 mg) in capsule Dietary Supplement: Caffeine 120 mg caffeine in capsules given one time only Other Name: 1,3,7-trimethylxanthine

2011 Clinical Trials

1636. Diet, Insulin Sensitivity And the Brain

with changes in insulin signaling pathways in peripheral fat and muscle tissue. Condition or disease Intervention/treatment Phase Obesity Diabetes Mellitus Type 2 Other: Meal size increase with HFHS Other: Meal size increase with HS Other: Meal frequency increase with HFHS Other: Meal frequency increase with HS Not Applicable Detailed Description: Lean, healthy, young men will follow a hypercaloric HF- or HFHS diet for 6 weeks. Before and after the dietary intervention, the investigators will perform (...) a SPECT-scan for serotonin and dopamine transporters with the radioligand [123I]FP-CIT, administered intravenously. The investigators will also perform a structural MRI for localization. Furthermore the investigators will perform a liver MRS and abdominal MRI for liver fat- and abdominal visceral fat measurement. The investigators will also perform a euglycemic, hyperinsulinemic clamp to measure insulin sensitivity and muscle- and fat biopsies to examine changes in insulin signaling pathways and fat

2011 Clinical Trials

1637. DGB-01 Effects on Endurance Exercise

: The purpose of this research is to evaluate the effects of DGB-01 on performance of a 40‐km time trial in trained male cyclists. The investigators believe that DGB-01 will improve performance on the time trial as measured by a reduction in the amount of time required to complete the distance, using a computerized cycle ergometer. Condition or disease Intervention/treatment Phase Fatigue Dietary Supplement: DGB-01 Supplementation Not Applicable Study Design Go to Layout table for study information Study (...) will be measured by cycling performance on a standardized 40-km time trial course. [ Time Frame: Individual participants will be followed for the duration of study enrollment, an expected average of 97 days. The study will remain open for up to 2 years or until subject number requirement is met. ] Time to complete the 40km time trial for subjects with DGB-01 intervention in period 1 (minimum 4 weeks of supplementation) versus the time for time trial completion of these subjects with casein in period 2 (minimum

2011 Clinical Trials

1638. The Effect of Potassium Bicarbonate on Bone and Several Physiological Systems During Immobilisation

different aspects like sports but also nutrition. Alkaline salts, abundant in fruits and vegetables, have shown to have positive effects on markers of bone turnover of postmenopausal women but also men and younger adults. With the current study the effects of a potassium bicarbonate supplementation added to a standardised, strictly controlled, definite diet of healthy, young men, should be verified within 21 days of 6°- HDT- Bedrest- the gold standard of simulating weightlessness within earthbound (...) deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 20 Years to 45 Years (Adult) Sexes Eligible for Study: Male Accepts Healthy Volunteers: Yes Criteria Inclusion Criteria: healthy male subjects age: 20- 45 weight 65- 85 kg height: 158- 190 cm BMI 20- 26 kg/m2 no high performance sports non- smoking (minimum 6 months

2011 Clinical Trials

1639. Elevated plasma creatinine due to creatine ethyl ester use. (Abstract)

Elevated plasma creatinine due to creatine ethyl ester use. Creatine is a nutritional supplement widely used in sport, physical fitness training and bodybuilding. It is claimed to enhance performance. We describe a case in which serum creatinine is elevated due to the use of creatine ethyl esther. One week after withdrawal, the plasma creatinine had normalised. There are two types of creatine products available: creatine ethyl esther (CEE) and creatine monohydrate (CM). Plasma creatinine

2011 Netherlands Journal of Medicine

1640. Creatine in type 2 diabetes: a randomized, double-blind, placebo-controlled trial. (Abstract)

Creatine in type 2 diabetes: a randomized, double-blind, placebo-controlled trial. Creatine supplementation improves glucose tolerance in healthy subjects.The aim was to investigate whether creatine supplementation has a beneficial effect on glycemic control of type 2 diabetic patients undergoing exercise training.A 12-wk randomized, double-blind, placebo-controlled trial was performed. The patients were allocated to receive either creatine (CR) (5 g·d) or placebo (PL) and were enrolled (...) effects were comparable between the groups.Creatine supplementation combined with an exercise program improves glycemic control in type 2 diabetic patients. The underlying mechanism seems to be related to an increase in GLUT-4 recruitment to the sarcolemma.© 2011 by the American College of Sports Medicine

2011 Medicine and science in sports and exercise Controlled trial quality: predicted high

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