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Sports Performance Supplement

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1561. The Effects of β-Hydroxy-β-methylbutyrate Free Acid and High-Intensity Interval Training

in skeletal muscle physiological cross-sectional area (PCSA=Volume/Fascicle length) and muscle quality (MQ=echo intensity) in the rectus femoris and vastus lateralis. Subjects: Fifty males and females between the ages of 18 - 35 will be recruited to participate in this study. Subject will be randomized to one of three groups: a control group (CTL), an HIIT only group (HIIT) or a group which will take the amino acid metabolite HMB and perform HIIT (HMB-HIIT). Individuals assigned to CTL will undergo (...) baseline testing. They will then be asked to continue their normal exercise routine for 4 weeks and will undergo post-testing after this time period. Study Protocol: Two testing sessions, on nonconsecutive days, will occur at least 72 hours prior to the start of the training period. The same testing protocols will be repeated at the end of the 4-week training period. Testing protocols include performance testing (VO2peak, lactate threshold, critical power, anaerobic working capacity and neuromuscular

2013 Clinical Trials

1562. Effect of Inorganic Nitrates (Beetroot Juice) on Arterial Hemodynamics and Exercise Capacity

. Crescenz VA Medical Center Information provided by (Responsible Party): Julio A.Chirinos, Corporal Michael J. Crescenz VA Medical Center Study Details Study Description Go to Brief Summary: The main objective is to test the hypothesis that inorganic nitrate supplementation will: (1) Improve exercise efficiency and performance; (2) Enhance the systemic vasodilator reserve during exercise and specifically, the vasodilator response in exercising muscle; (3) Reduce arterial wave reflections and arterial (...) juice Subjects will receive 140 mL of Nitrate-rich concentrated beetroot juice. Other Name: Beet It Stamina Sports shots Placebo Comparator: Nitrate depleted beetroot juice Subjects with heart failure with preserved ejection fraction will receive 140 mL of nitrate-depleted beetroot juice (containing <0.01 mmol of NO-3).This will be a cross-over study. Therefore all subjects will receive both interventions, but the order of the interventions will be randomized. Dietary Supplement: Nitrate depleted

2013 Clinical Trials

1563. Effects of Traumeel®S Tablets on Recovery and Inflammatory Immune Response After Repeated Bouts of Exercise

BMI ≥ 18.5 and < 27,5 kg/m2 (WHO standard for normal range BMI) Maximum relative oxygen uptake (VO2max) < 53 ml/kg x min General state of good health Non-smoker Medically approved unrestricted participation in sports as shown by diagnostic performance test conducted on treadmill no longer than 3 months prior to study entry Willingness to provide signed informed consent Exclusion Criteria: Weekly training volume ≥ 6 hours Use of dietary supplements (incl. high-dosed vitamins and minerals) Chronic (...) of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its identifier (NCT number): NCT01921777 Locations Layout table for location information Germany Department of Sports Medicine, Institute of Sports Science, University of Giessen Giessen, Germany, 35394 Sponsors and Collaborators Prof. Dr. med. Frank Christoph Mooren Biologische Heilmittel Heel GmbH

2013 Clinical Trials

1564. A Study of Tadalafil for Duchenne Muscular Dystrophy

designed for ambulant boys with DMD that can provide additional information on motor functions important in maintaining normal ambulation and other activities important to everyday life. The NSAA is a 17-item evaluation of standing, ability to transition from lying to sitting, sitting to standing, and other mobility assessments. Each of the 17 items is evaluated on an ordinal scale of 0, 1, or 2, with higher scores reflecting better performance on the assessment, for a total maximum score of 34 (...) tests included time it took to rise from floor, walk 10 meters, ascend 4 stairs, and descend 4 stairs.The lower the time in seconds taken, the better the performance. The LS mean change from baseline, standard error, was derived using mixed model repeated measures methodology (MMRM) with factors for pooled country, treatment, visit, treatment-by-visit interaction and Day 1 value as baseline covariate. Time to Persistent 10% Worsening in 6MWD [ Time Frame: Baseline through Week 48 ] Time on study

2013 Clinical Trials

1565. Effect of Omega-3 Phospholipids on Perceptual-cognitive Training

of the sessions. Dietary Supplement: Omega-3 The capsule will be take daily for 4 weeks before and for the duration of the tests of the perceptual-cognitive training protocol. The testing period will held at intervals of 3 to 7 days for 5 sessions (maximum of 5 weeks testing). Taking products will be made more specifically 30 minutes before the start of the sessions. Other Name: health Canada product number 80006416 Outcome Measures Go to Primary Outcome Measures : Speed-thresholds performance [ Time Frame: 6 (...) of visual information in the brain and in particular the attention and perceptual-cognitive learning in a three dimensions environment. Eighty subjects (40 young (18-35 years) and 40 older (60-75 years)) divided into four groups, two Omega-3 (20 young and 20 older) and two other placebo (20 young and 20 elderly ), will in this study, performing a complex perceptual-cognitive task such as the pursuit of moving objects in a 3D space. This stimulus was chosen because it is very similar to the situations

2013 Clinical Trials

1566. Physiologic Adaptations to Interval and Continuous Running at Low Volume and Vigorous Intensity Over 14-Weeks.

performed on a treadmill for a period of 14 weeks, with a frequency of three times a week, lasting 20-minutes per session thus completing 46 sessions of training. The intensity and volume of training both were adapted according to the recommendations of the American College of Sports Medicine. The interval training group intensities ranged between 84-87% of maximal heart rate (HRmax) (vigorous intensity), 88-93%HRmax (near maximum intensity) and 94-99% HRmax (maximum intensity). Other: running training (...) of the American College of Sports Medicine.The continuous group ran at an intensity of ~87% of maximal heart rate (HRmax) Other: running training The present study was designed to compare the physiological effects between the two training regimes and the control group.The subjects from interval and continuous group performed others activities as resistance training, swimming or soccer. Those activities wasn't controlled by our study, but the individual didn't do physical activities at least 3 hours before

2013 Clinical Trials

1567. Vitamin D2, Muscle Damage, NASCAR Pitcrew

of the impact of vitamin D on muscle function (Scand J Med Sci Sports. 2010;20:182-90). In the early 20th century, athletes and coaches felt that ultraviolet rays had a positive impact on athletic performance, and evidence is accumulating to support this view. Both cross-sectional and longitudinal studies support a functional role for vitamin D in muscle, and the discovery of the vitamin D receptor in muscle tissue provides a mechanistic pathway for understanding the role of vitamin D within muscle. Studies (...) soreness (DOMS) in athletes. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 33 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Investigator) Primary Purpose: Prevention Official Title: Influence of 6-weeks Supplementation With Vitamin D Portobello Mushroom Powder on Muscle Function and Performance, Innate Immune Function, and Exercise-induced Muscle Damage and DOMS in NASCAR

2013 Clinical Trials

1568. Muscle Oxygenation, Type 1 Diabetes, and Glycated Hemoglobin

test starts 2-4h after a standardised breakfast. After a 2-min resting period sitting on the cycle ergometer (Excalibur Sport, Lode B.V, Medical Technology, Groningen, Netherlands), the test starts at 30 watts with a 20 watts increment every 2min until exhaustion. Dietary Supplement: Oral Glucose Tolerance Test The subjects arrive after an overnight fast and have a 75g Glucose Oral Charge. Procedure: Muscle biopsy A sample of vastus lateralis (less than 150mg) is taken with a specific needle under (...) Intervention/treatment Type 1 Diabetes Behavioral: Incremental maximal exercise Dietary Supplement: Oral Glucose Tolerance Test Procedure: Muscle biopsy Procedure: Combined DLCO-DLNO Procedure: Dual energy X-ray absorptiometry Procedure: Accelerometry over one week Other: Questionnaires Detailed Description: The current study aims at assessing the impact of Type 1 diabetes and HbA1c on muscle oxygen delivery and on muscle mitochondrial capacity. Our hypothesis is that these both steps of the oxygen cascade

2013 Clinical Trials

1569. Exercise to Prevent Aromatase Inhibitor Side Effects in Breast Cancer Patients

: Arms and Interventions Go to Arm Intervention/treatment Experimental: Structured Exercise Structured and supervised aerobic and resistance training 2 times per week Other: Structured Exercise Structured and supervised aerobic and resistance training 2 times per week Active Comparator: Usual Care Subjects will be counseled on American Cancer Society and American College of Sports Medicine physical activity and nutritional guidelines at the initiation of the study. Study participants (...) will be contacted by a physician or nurse on weeks 2, 6, 10, and 14 to provide support and encouragement to patients. Other: Usual Care Subjects will be counseled on American Cancer Society and American College of Sports Medicine physical activity and nutritional guidelines at the initiation of the study. Study participants will be contacted by a physician or nurse on weeks 2, 6, 10, and 14 to provide support and encouragement to patients. Outcome Measures Go to Primary Outcome Measures : Fatigue [ Time Frame

2013 Clinical Trials

1570. Effect of Allopurinol Administration on the Prevention of Muscle Mass Loss in Subject Immobilized.

Sponsor: Instituto de Investigacion Sanitaria La Fe Information provided by (Responsible Party): Instituto de Investigacion Sanitaria La Fe Study Details Study Description Go to Brief Summary: Generating critical levels of power is a prerequisite for performing simple daily activities, such as rising from a chair or climbing stairs. For a young healthy person these activities can be performed easily, however after a prolonged period of forced inactivity (such as during the recovery from a sports (...) patients, i.e. 300 mg/day orally, during all the immobilization period, which will last fifteen days. This medication will be delivered to the patients when they agree to participate in the clinical trial. They will be immobilized by posterior knee splint, preventing use of that leg. We will determine muscle mass loss by performing two magnetic resonances of both legs before and after the immobilization period. We will also take two blood samples (before and after immobilization) to measure oxidative

2013 Clinical Trials

1571. Fixation Using Alternative Implants for the Treatment of Hip Fractures (FAITH-2)

all patients require surgical repair of their fractures and unlike elderly hip fractures, failure of surgery offers few options for salvage. Arthroplasty is a successful treatment for elderly patients; however, a hip replacement is not a viable option for younger patients because of their higher functional demands for work and recreational activities that are not tolerated by joint replacements. There is more than one way to perform internal fixation for femoral neck fractures. Cancellous screws (...) , musculoskeletal health, and improved fracture healing. Experimental animal studies have demonstrated the concentration of vitamin D metabolites are higher at a fracture callus compared to the uninjured contralateral bone, vitamin D supplementation leads to decreased time to fracture union and increased callus vascularity, and vitamin D increases mechanical bone strength compared to controls. Clinical studies have also demonstrated that vitamin D supplementation increases the callus volume of proximal humerus

2013 Clinical Trials

1572. Treatment of large cystic medial osteochondral lesions of the talus with autologous osteoperiosteal cylinder grafts. (Abstract)

transplantation of autologous osteoperiosteal cylinder graft, which was harvested from the ipsilateral iliac crest. The visual analog scale score for pain during daily activities, American Orthopaedic Foot & Ankle Society hindfoot and ankle scores, and subjective satisfaction survey rating were obtained. Plain radiographs and magnetic resonance imaging of the ankle were obtained before and after surgery. In 13 cases second-look arthroscopy was performed 12 months postoperatively and the cartilage repair (...) was assessed with the criteria of the International Cartilage Repair Society.Sixteen patients were available for follow-up at a mean of 32.6 months (range, 24 to 48 months). The mean visual analog scale score decreased from 5.51 ± 0.83 preoperatively to 0.98 ± 0.98 at the latest follow-up, and the median American Orthopaedic Foot & Ankle Society score improved from 75 preoperatively to 90 at the latest follow-up. Seven patients resumed sporting activities. Overall, 7 patients rated the result as excellent

2013 Arthroscopy

1573. The effect of caffeine ingestion on skill maintenance and fatigue in epee fencers. (Abstract)

The effect of caffeine ingestion on skill maintenance and fatigue in epee fencers. The ergogenic effect of caffeine on sports performance focuses predominantly on endurance sports (Doherty & Smith, 2004 ) with little research on intermittent high intensity sports. This study aimed to explore the effect of caffeine ingestion on skill maintenance following fencing simulated exercise. Eleven competitive fencers participated (four female; seven male; age 33 ± 6.5 years). Following a maximal test (...) to exhaustion, fencers completed two trials assessing accuracy and reaction times (Stroop test) before and after a fatiguing protocol designed to simulate the demands of a fencing competition. Skill testing involved 30 lunges to hit a target. 500 ml placebo or 3 mg · kg(-1) caffeine supplemented drink was administered after the initial reaction and skill tests in a single-blind crossover design. The fatiguing protocol involved simulating six fights with 6-minute rests between each. Fencers rated

2013 Journal of sports sciences Controlled trial quality: uncertain

1574. Training table to the battlefield: protein recommendations for warfighters. Full Text available with Trip Pro

been tailored for these populations. Like athletes, warfighters consider protein a critical component of their diet and often incorporate protein supplements into daily diet plans. This article highlights sports nutrition principles that target energy and protein needs of athletes, considers the basis of these recommendations in the context of protein supplementation, and asserts that translating these recommendations to the warfighter is appropriate and necessary. The recommended range of protein (...) Training table to the battlefield: protein recommendations for warfighters. Warfighters represent a population of athletes for whom routine training and physical expectations for military operations parallel, and very often exceed, those of their civilian counterparts. Like athletes, warfighters require nutrition support to optimize physical condition to maintain training, sustain performance, speed recovery, and prevent injury and illness. Specifically, energy and protein requirements have

2013 Journal of Nutrition

1575. A 60day double-blind, placebo-controlled safety study involving Citrus aurantium (bitter orange) extract. (Abstract)

A 60day double-blind, placebo-controlled safety study involving Citrus aurantium (bitter orange) extract. Bitter orange (Citrus aurantium) extract and its primary protoalkaloid p-synephrine are widely consumed in dietary supplements for weight management and sports performance. p-Synephrine is also present in foods derived from a variety of Citrus species. Bitter orange extract is commonly used in combination with multiple herbal ingredients. Most clinical studies conducted on bitter orange

2013 Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

1576. Comparison of Pre-exercise Beta-hydroxy-beta-methylbutyrate Free Acid (HMB-FA) and Cold Water Therapy for the Attenuation of Muscle Damage and Soreness

of the squat exercise only using the same loading pattern and rest interval length as T2. Following the T2 and T3 workouts subjects in CT will undergo no treatment; subjects in CW will be required to sit in a whirlpool tub for 10-min up to their umbilicus in water at 50° F - 54° F (10° C - 12° C); subjects in HMB-FA will be provided the supplement 30 min prior each workout and CW+HMB-FA will be administered together at time points describe above. Statistical Analysis Statistical evaluation of performance (...) nutritional supplement or performance enhancing drug (determined from health and activity questionnaire). Any chronic illness that causes continuous medical care Taking any type of prescription or over-the-counter medication, having any chronic illness causing you to seek medical care, pregnancy Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided

2013 Clinical Trials

1577. Effect of Tongkat Ali on stress hormones and psychological mood state in moderately stressed subjects. Full Text available with Trip Pro

Effect of Tongkat Ali on stress hormones and psychological mood state in moderately stressed subjects. Eurycoma longifolia is a medicinal plant commonly called tongkat ali (TA) and "Malaysian ginseng." TA roots are a traditional "anti-aging" remedy and modern supplements are intended to improve libido, energy, sports performance and weight loss. Previous studies have shown properly-standardized TA to stimulate release of free testosterone, improve sex drive, reduce fatigue, and improve well (...) -being.We assessed stress hormones and mood state in 63 subjects (32 men and 31 women) screened for moderate stress and supplemented with a standardized hot-water extract of TA root (TA) or Placebo (PL) for 4 weeks. Analysis of variance (ANOVA) with significance set at p < 0.05 was used to determine differences between groups.Significant improvements were found in the TA group for Tension (-11%), Anger (-12%), and Confusion (-15%). Stress hormone profile (salivary cortisol and testosterone

2013 Journal of the International Society of Sports Nutrition Controlled trial quality: uncertain

1578. What Does The Death of Robert Atkins Tell Us About the Atkins Diet?

cannot base decisions on what diet plan is healthy or effective for weight loss on the outcome of one patient. It doesn’t matter how famous that one person is or whether he/she originated and meticulously followed the diet. It is a ludicrous concept. Would you base your decision to engage in running based on the death of ? Fixx did much to popularize the sport of running and the concept of jogging as a source of health benefit and weight loss. He died while jogging, in fact. An autopsy concluded (...) obese man. Atkins actually weight around 200 pounds through most of his life and a hospital note on admission showed him weighing 195 pounds. A substantial weight gain of 63 pounds occurred in the 9 days after his admission due to the accumulation of fluid volume and swelling which is not uncommon in the critically ill. No autopsy was performed on Atkins but the NYME wrote on the document that he had “h/o of MI, CHF, HTN.” MI is the acronym for a myocardial infarction or heart attack. As far as we

2016 The Skeptical Cardiologist

1579. Should I Have Meniscus Surgery?

damage to the structure of the knee? This is assuming that the knee does not lock and pain is minimal. I am a very active 20 something that is involved in contact sports similar to wrestling. I am still training and perform reasonably well. The only time my knee feels uncomfortable is when its in full flexion, heel touching my butt – my knee would pop but without pain. I am able to modify my activities/ movements that do not put me in that position too often… Thanks, Louis says: Louis… in general (...) or stitched back into place. Most procedures take 15-45 minutes and you are able to go home the same day. Whether or not you can return to sports soon will depend on which procedure you had — repair versus removal. More on the here. So if you have a meniscus tear, it’s not all doom and gloom. Many tears do not require meniscus surgery. Some of them do. Some meniscus tears are repairable. Sometimes the torn portion of the meniscus is simply removed. This tear is displaced and caught between the two bones

2016 Howard J. Luks, MD blog

1580. Get a grip…

Get a grip… Get a grip… | The Sports Physio Simple, practical, honest advice Menu / You can get a lot of information from a handshake. A good, firm, vigorous handshake often tells me the individual is strong, healthy, interested and enthusiastic. However, a weak, limp, flaccid handshake often tells me the individual is cautious, timid, weak, lethargic or disinterested. And the over-the-top bone crusher handshake usually tells me the individual is trying to assert their dominance or trying (...) is preferred, and in the Middle East you never offer your left hand to shake as it’s a great insult, and a woman’s hand is never to be touched unless it is offered by her. The handshake has also evolved some rather bizarre rituals that can signify membership to a secret club or organisation, and in sports, they are often used to celebrate achievements with intricate and synchronised, fist bumps, hand slaps, and arm movements that boggle the mind. Check it! Now I always shake my patients hands when I greet

2016 The Sports Physio blog

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