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Sports Performance Supplement

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1561. Exercise-Induced Asthma

grams before Dietary salt reduction Omega 3 supplementation Avoid s (e.g. ) in Exercise-Induced Asthma (unless ) Consistent use results in worsening symptoms and decreased short-acting (rescue ) effect If s are used in Exercise-Induced Asthma, avoid use >3 days per week X. Guidelines: Sporting organization rules regarding restricted medications for Asthma Organizations United States Olympic Committee (USOC) National Collegiate Athletic Association (NCAA) No approval needed Leukotriene Modifiers (...) . Management: General Measures Maintain regular for physical conditioning Warm up and cool down for 10 minutes before and after in humidified, warm environment Cover nose and mouth during cold weather Consider heat exchange mask (available at sporting good stores) Avoid within 2 hours following a meal Avoid in high allergen, ozone or pollution IX. Management: Medications Treat related conditions Primary Agents ( , ) Use 2 puffs, 15-30 minutes before Secondary Adjunctive Agents Step 1: Leukotriene Modifiers

2015 FP Notebook

1562. Potential ergogenic activity of grape juice in runners. (PubMed)

Potential ergogenic activity of grape juice in runners. Recent studies have indicated that certain food products have ergogenic potential similar to that of sports supplements. The present study aimed to investigate the potential ergogenic effect of integral purple grape juice on the performance of recreational runners. Twenty-eight volunteers of both sexes (age, 39.8 ± 8.5 years; peak oxygen consumption, 43.2 ± 8.5 mL/(kg·min)) were randomized into either a group that received grape juice (...) (grape juice group (GJG), n = 15; 10 mL/(kg·min) for 28 days) or a group that received an isocaloric, isoglycemic, and isovolumetric control beverage (control group (CG), n = 13). A time-to-exhaustion exercise test, anaerobic threshold test, and aerobic capacity test were performed, together with assessments of markers of oxidative stress, inflammation, immune response, and muscle injury, performed at baseline and 48 h after the supplementation protocol. The GJG showed a significant increase (15.3

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2015 Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme

1563. Creatine in type 2 diabetes: a randomized, double-blind, placebo-controlled trial. (PubMed)

Creatine in type 2 diabetes: a randomized, double-blind, placebo-controlled trial. Creatine supplementation improves glucose tolerance in healthy subjects.The aim was to investigate whether creatine supplementation has a beneficial effect on glycemic control of type 2 diabetic patients undergoing exercise training.A 12-wk randomized, double-blind, placebo-controlled trial was performed. The patients were allocated to receive either creatine (CR) (5 g·d) or placebo (PL) and were enrolled (...) effects were comparable between the groups.Creatine supplementation combined with an exercise program improves glycemic control in type 2 diabetic patients. The underlying mechanism seems to be related to an increase in GLUT-4 recruitment to the sarcolemma.© 2011 by the American College of Sports Medicine

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2011 Medicine and science in sports and exercise

1564. Effects of p-synephrine alone and in combination with selected bioflavonoids on resting metabolism, blood pressure, heart rate and self-reported mood changes. (PubMed)

Effects of p-synephrine alone and in combination with selected bioflavonoids on resting metabolism, blood pressure, heart rate and self-reported mood changes. Bitter orange (Citrus aurantium) extract is widely used in dietary supplements for weight management and sports performance. Its primary protoalkaloid is p-synephrine. Most studies involving bitter orange extract and p-synephrine have used products with multiple ingredients. The current study assessed the thermogenic effects of p

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2011 International journal of medical sciences

1565. Quantitation of plasma 13C-galactose and 13C-glucose during exercise by liquid chromatography/isotope ratio mass spectrometry. (PubMed)

Quantitation of plasma 13C-galactose and 13C-glucose during exercise by liquid chromatography/isotope ratio mass spectrometry. The utilisation of carbohydrate sources under exercise conditions is of considerable importance in performance sports. Incorporation of optimal profiles of macronutrients can improve endurance performance in athletes. However, gaining an understanding of the metabolic partitioning under sustained exercise can be problematical and isotope labelling approaches can help (...) and glucose required a correction routine to be implemented to allow the measurement, and correction, of plasma glucose δ(13)C, even in the presence of very highly enriched galactose. A Bland-Altman plot of glucose concentration measured by LC/IRMS against glucose measured by an enzymatic method showed good agreement between the methods. Data from seven trained cyclists, undergoing galactose supplementation before exercise, demonstrate that galactose is converted into glucose and is available

2011 Rapid communications in mass spectrometry : RCM

1566. Elevated plasma creatinine due to creatine ethyl ester use. (PubMed)

Elevated plasma creatinine due to creatine ethyl ester use. Creatine is a nutritional supplement widely used in sport, physical fitness training and bodybuilding. It is claimed to enhance performance. We describe a case in which serum creatinine is elevated due to the use of creatine ethyl esther. One week after withdrawal, the plasma creatinine had normalised. There are two types of creatine products available: creatine ethyl esther (CEE) and creatine monohydrate (CM). Plasma creatinine

2011 Netherlands Journal of Medicine

1567. Characterization and Detection of Prolonged Endothelin Receptors Antagonists Administration

study ERA will be administered in newly approved doses for 8 weeks in order to assess the presumed doping potential for both male and female athletes, and to monitor serum and urinary ERA excretion dynamics after single- and multiple-dose administration. The possible effects of prolonged ERA administration in higher doses on exercise performance may be relevant, if further confirmed, in terms of their possible fraudulent utilization to influence exercise performance in sports, raising the difficult (...) for Health, Exercise and Sport Sciences, Serbia Information provided by: Center for Health, Exercise and Sport Sciences, Serbia Study Details Study Description Go to Brief Summary: Endothelin receptors antagonists (ERA), such as bosentan and ambrisentan, are a class of vasoactive drugs that have been developed for the treatment of pulmonary arterial hypertension. It has been anecdotally reported that ERA is frequently used among top-level athletes to counteract exercise-induced rise in pulmonary vascular

2011 Clinical Trials

1568. Diet, Insulin Sensitivity And the Brain

with changes in insulin signaling pathways in peripheral fat and muscle tissue. Condition or disease Intervention/treatment Phase Obesity Diabetes Mellitus Type 2 Other: Meal size increase with HFHS Other: Meal size increase with HS Other: Meal frequency increase with HFHS Other: Meal frequency increase with HS Not Applicable Detailed Description: Lean, healthy, young men will follow a hypercaloric HF- or HFHS diet for 6 weeks. Before and after the dietary intervention, the investigators will perform (...) a SPECT-scan for serotonin and dopamine transporters with the radioligand [123I]FP-CIT, administered intravenously. The investigators will also perform a structural MRI for localization. Furthermore the investigators will perform a liver MRS and abdominal MRI for liver fat- and abdominal visceral fat measurement. The investigators will also perform a euglycemic, hyperinsulinemic clamp to measure insulin sensitivity and muscle- and fat biopsies to examine changes in insulin signaling pathways and fat

2011 Clinical Trials

1569. DGB-01 Effects on Endurance Exercise

: The purpose of this research is to evaluate the effects of DGB-01 on performance of a 40‐km time trial in trained male cyclists. The investigators believe that DGB-01 will improve performance on the time trial as measured by a reduction in the amount of time required to complete the distance, using a computerized cycle ergometer. Condition or disease Intervention/treatment Phase Fatigue Dietary Supplement: DGB-01 Supplementation Not Applicable Study Design Go to Layout table for study information Study (...) will be measured by cycling performance on a standardized 40-km time trial course. [ Time Frame: Individual participants will be followed for the duration of study enrollment, an expected average of 97 days. The study will remain open for up to 2 years or until subject number requirement is met. ] Time to complete the 40km time trial for subjects with DGB-01 intervention in period 1 (minimum 4 weeks of supplementation) versus the time for time trial completion of these subjects with casein in period 2 (minimum

2011 Clinical Trials

1570. Carotenoid Response to the Intake of Vegetables and Fruits

and 2/day for men, use of nutritional/sports supplements (if unwilling to discontinue during the study) Pregnancy or lactating Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its identifier (NCT number): NCT01403844 Locations Layout table for location information United States (...) Raman spectroscopy to assess vegetable and fruit intake by performing a controlled feeding study during which volunteers will consume a provided diet with known amounts of carotenoids in the form of fruits and vegetables. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 29 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Basic Science Official Title: Skin Carotenoid Response

2011 Clinical Trials

1571. Effects of Theobromine and Caffeine on Mood, Cognition and Blood Pressure

Details Study Description Go to Brief Summary: The purpose of this study was to measure potential mood, cognition and blood pressure effects of theobromine and caffeine in healthy women Condition or disease Intervention/treatment Phase Mood Dietary Supplement: theobromine Dietary Supplement: Caffeine Dietary Supplement: caffeine + theobromine Dietary Supplement: placebo Not Applicable Detailed Description: Background Previous research has shown that naturally occurring chocolate ingredients (...) Resource links provided by the National Library of Medicine related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Active Comparator: theobromine theobromine (700 mg) in capsule Dietary Supplement: theobromine 700 mg theobromine in gelatin capsules given one time only Other Name: 3,7-dimethylxanthine Active Comparator: caffeine caffeine (120 mg) in capsule Dietary Supplement: Caffeine 120 mg caffeine in capsules given one time only Other Name: 1,3,7-trimethylxanthine

2011 Clinical Trials

1572. The Effect of Potassium Bicarbonate on Bone and Several Physiological Systems During Immobilisation

different aspects like sports but also nutrition. Alkaline salts, abundant in fruits and vegetables, have shown to have positive effects on markers of bone turnover of postmenopausal women but also men and younger adults. With the current study the effects of a potassium bicarbonate supplementation added to a standardised, strictly controlled, definite diet of healthy, young men, should be verified within 21 days of 6°- HDT- Bedrest- the gold standard of simulating weightlessness within earthbound (...) deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 20 Years to 45 Years (Adult) Sexes Eligible for Study: Male Accepts Healthy Volunteers: Yes Criteria Inclusion Criteria: healthy male subjects age: 20- 45 weight 65- 85 kg height: 158- 190 cm BMI 20- 26 kg/m2 no high performance sports non- smoking (minimum 6 months

2011 Clinical Trials

1573. Effects of Caffeine in Hydration and Energy Metabolism

the experimental trial to assure that the same diet and physical activity patterns were maintained. Also it was analyzed if the effect of caffeine was independent of body composition, assessed by dual-energy x-ray absorptiometry. To perform this research study, a total of 30 non-smoker males, low caffeine users (<100 mg/day), aged 20-39 yrs [body mass (BM): 72.7 ± 8.8 kg; Height: 1.77 ± 0.07 m] were followed in a double-blind crossover experimental design with two conditions in a random sequence: caffeine (5 (...) mg per kg of BM/day) and malt-dextrine as placebo, both through capsules. Conditions lasted for 4 days with a 3-day washout period. Evaluations were performed at baseline (visit-1), end of condition 1 (visit-2), and end of condition 2 (visit-3). Fat and fat-free masses (FFM) were assessed by dual energy x-ray absorptiometry. TBW and ECW were determined by dilution techniques (deuterium and bromide, specifically) while ICW was calculated as the difference between TBW and ECW (Schoeller et al

2011 Clinical Trials

1574. Recreational football for disease prevention and treatment in untrained men: a narrative review examining cardiovascular health, lipid profile, body composition, muscle strength and functional capacity. (PubMed)

controlled trial, published in the BJSM in January 2009, showed that football increased maximal oxygen uptake and muscle and bone mass, and lowered fat percentage and blood pressure, in untrained men, and since then more than 70 articles about football for health have been published, including publications in two supplements of the Scandinavian Journal of Medicine and Science in Sports in 2010 and 2014, prior to the FIFA World Cup tournaments in South Africa and Brazil. While studies of football training (...) effects have also been performed in women and children, this article reviews the current evidence linking recreational football training with favourable effects in the prevention and treatment of disease in adult men.Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to

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2015 British Journal of Sports Medicine

1575. Clinical Guideline on the Treatment of Carpal Tunnel Syndrome

, antidepressants and NSAIDs), nutritional supplements, phonophoresis, smoking cessation, systemic steroid injection, therapeutic touch, vitamin B6 (pyridoxine), weight reduction, yoga. (Inconclusive, Level II and V) Recommendation 5 We recommend surgical treatment of carpal tunnel syndrome by complete division of the flexor retinaculum regardless of the specific surgical technique. (Grade A, Level I and II) Recommendation 6 We suggest that surgeons do not routinely use the following procedures when performing (...) after three voting rounds, no recommendation is adopted. ARTICLE INCLUSION AND EXCLUSION CRITERIA Inclusion and exclusion criteria were developed a priori. Articles were retrieved and included only if they met these specific inclusion and exclusion criteria (see Appendix II: Article Inclusions and Exclusions). Supplemental searches were conducted to identify national rates and other information relevant to performance measures. Work Group members were given the opportunity to supplement the searches

2008 Congress of Neurological Surgeons

1576. Eating disorders toolkit, a practice based guide to the inpatient management of adolescents with eating disorders, with special reference to regional and rural areas

and will depend, in part, on their level of insight to the illness as well as their medical and psychological status at the time. Parent or carer input is required to validate or supplement some of the interview findings. ? Involve the patient and family in assessment, treatment and discharge planning. ? Adolescents are still growing and developing. Physical consequences of the eating disorder may be irreversible, though may be treatable if intervention is timely. ? See Appendix 5 for examples of psychometric (...) , difficulties) Eating Disorders Toolkit - Assessment and Treatment Planning 18 PAST AND CO-MORBID PSYCHIATRIC HISTORY 1. Past psychiatric history and treatment 2. Co-morbid conditions (mood and anxiety disorders are common) 3. Other psychological history including neglect, trauma, depression, self-harm, suicidal thoughts and bullying 4. Personality traits (e.g., perfectionism, obsessiveness) SOCIAL AND FAMILY HISTORY 1. Personal interests (e.g., hobbies, sport, recreations) and strengths 2. History

2008 Clinical Practice Guidelines Portal

1577. Clinical guidelines for the diagnosis and management of early rheumatoid arthritis

of rheumatoid arthritis 19 Multidisciplinary care and care planning 19 Patient information and education 19 Psychosocial support 20 Sleep patterns and fatigue 21 Pharmacological interventions for RA 22 Simple analgesics (eg. paracetamol) 22 Fatty acid supplements (omega-3 and gamma-linolenic acid) 22 Traditional non-steroidal anti-inflammatory drugs and COX-2 inhibitors 23 Disease modifying antirheumatic drugs 25 Corticosteroids 26 Complementary medicines 27ii Clinical guideline for the diagnosis (...) working within a multidisciplinary team. These include, but are not limited to, physiotherapists, nurses, occupational therapists, sports medicine personnel, podiatrists, dieticians, psychologists, pharmacists and community health workers. The guideline is applicable to primary care settings in metropolitan, regional, rural, and remote areas of Australia. The guideline focuses on the diagnosis and management of adults with early stage RA. The early stage of RA is defined as ‘disease duration of less

2009 The Royal Australian College of General Practitioners

1578. Opioid prescription in chronic pain conditions guidelines for South Australian general practitioners

, and diversion. By establishing treatment expectations for each patient, and structuring therapy appropriately, GPs can identify these patients who are at risk, help those who may need controls to manage the therapy responsibly, and provide monitoring necessary for safe and effective prescribing. GPs should consider the following approaches in developing a universal precautions approach: 1. In assessing patients for opioid therapy, take a detailed history and perform an appropriate physical examination (...) in function may be demonstrated by improved sleep patterns, and ability to relieve incident pain by resting and waiting for the pain to ease over time. It is rare for complete pain relief to occur. For some patients, pain relief may be meaningful when specific tasks can be performed, mood improves, sleep is better, or relationships with others can occur. The monitoring of pain intensity is important but the GP needs to assess all activities of daily living in an effort to understand the overall effects

2008 Clinical Practice Guidelines Portal

1579. Diagnostic arthroplasty for conditions of the knee

and reference test among consecutive or non-consecutive patients. Diagnostic performance outcomes examined included specificity, sensitivity, likelihood ratios and predictive values. Safety outcomes examined included pain, patholaxity, complications related to anaesthesia, haemarthrosis, infection, deep vein thrombosis and knee stiffness. Methods Studies were identified by searching BMJ Clinical Evidence, the York (UK) Centre for Reviews and Dissemination (CRD), the Cochrane Library, PubMed and EMBASE from (...) reviews are summarised below. 1. For meniscal lesions and ACL tears, MRI is an effective diagnostic tool when compared to diagnostic arthroscopy. In particular, MRI has a high specificity and negative predictive value, suggesting that screening MRI studies can effectively rule out the presence of meniscal lesions and ACL tears and reduce the number of unnecessary diagnostic arthroscopies performed. MRI is useful in situations where the results of a clinical examination are uncertain


1580. “I don’t like Cricket, oh no, I…” used it to inspire this blog!

! The added scourge of EIMD includes increased stiffness, swelling, decreased strength and power and altered proprioception. , Left alone, EIMD and DOMS usually resolve clinically after four to five days and athletes can return to pre-EIMD training levels. And here in belies the plight of physios, coaches and athletes alike. Anything less than 100% can be the difference between a performance nonpareil or a seasons work undone. In most sporting events (think Tour de France, Wimbledon [Murray on a good run (...) ], Test Match Cricket [ok, so I’m talking key fast bowlers and batsmen not out for <10 runs over two innings!]), a 5-day wait for a full force flexion of the is 3 to 4 days too long. Strategies to help reduce the effects of DOMS and allow a hastier return to full training or competition are like catnip to the high level sports arena. Massage, nutritional supplements and anti-inflammatory medications have all made the list, ice baths being the latest panacea. The problem with all these strategies

2014 David Nunan's blog

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