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Sporotrichosis

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81. Sporotrichosis (Diagnosis)

Sporotrichosis (Diagnosis) Dermatologic Manifestations of Sporotrichosis: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA5MTE1OS1vdmVydmlldw== processing > Dermatologic (...) Manifestations of Sporotrichosis Updated: May 17, 2016 Author: Scott D Miller, MD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Dermatologic Manifestations of Sporotrichosis Overview Background Sporotrichosis is a subcutaneous or systemic infection caused by Sporothrix schenckii , a rapidly growing dimorphic fungus. The organism derives its name from R B Schenck, who first reported the infection in 1898. Sporothrix species typically exist as a saprophytic mold

2014 eMedicine.com

82. An Unusual Presentation of Sporotrichosis (Full text)

An Unusual Presentation of Sporotrichosis Sporotrichosis can mimic a few diseases. Sporotrichosis presenting as a hypoaesthetic plaque or plaque suggestive of leprosy has not been mentioned in literature. Herein we present a case of a 26 years old man who presented with hypoesthetic plaque on left ankle and was clinically diagnosed to have borderline tuberculoid leprosy who later developed few nodules in linear fashion on left leg, which ruptured to form non healing ulcers. Culture from ulcer

2013 Indian journal of dermatology PubMed

83. Report of 457 sporotrichosis cases from Jilin province, northeast China, a serious endemic region. (PubMed)

Report of 457 sporotrichosis cases from Jilin province, northeast China, a serious endemic region. Most reported sporotrichosis cases came from South American countries, the USA, India and Japan. This mycosis is also endemic in Northeast China. However, the situation is not clear for international researchers due to lack of large series reported in English.To report and analyse 457 sporotrichosis cases.Retrospective study of 457 cases of sporotrichosis diagnosed by fungal culture at the First (...) %) showed lymphocutaneous form, 252 patients (55.14%) showed fixed form, 8 patients (1.75%) showed disseminated cutaneous sporotrichosis and the clinical form of 7 patients (1.53%) could not be defined. Extremities and nodules were the most frequently involved sites and founded manifestation. Main histopathology findings were suppurative granuloma, tuberculoid granuloma and mixed inflammatory granuloma. A total of 75 cases (19.74%) had fungal elements revealed by Periodic Acid-Schiff staining. Patients

2013 Journal of the European Academy of Dermatology and Venereology

84. Sporotrichosis in renal transplant patients (Full text)

Sporotrichosis in renal transplant patients The current report describes two renal transplant recipients who presented with sporotrichosis. In addition, the authors review the general aspects of sporotrichosis in renal transplant recipients reported in the literature. Sporotrichosis is a rare fungal infection in transplant patients and has been reported primarily in renal transplant recipients not treated with antifungal prophylaxis. Extracutaneous forms of sporotrichosis without skin (...) manifestations and no previous history of traumatic injuries have been described in such patients and are difficult to diagnose. Renal transplant recipients with sporotrichosis described in the present report were successfully treated with antifungal therapy including amphotericin B deoxycholate, lipid amphotericin B formulations, fluconazole and itraconazole.

2013 The Canadian Journal of Infectious Diseases & Medical Microbiology PubMed

85. Sporotrichosis Mimicking Keratoacanthoma (Full text)

Sporotrichosis Mimicking Keratoacanthoma 22556066 2012 06 25 2019 03 09 1476-1645 86 5 2012 May The American journal of tropical medicine and hygiene Am. J. Trop. Med. Hyg. Sporotrichosis mimicking keratoacanthoma. 741 10.4269/ajtmh.2012.11-0681 Lauermann Fernanda F Lyra Marcelo M Gaudio Raquel R eng Case Reports Journal Article United States Am J Trop Med Hyg 0370507 0002-9637 304NUG5GF4 Itraconazole AIM IM Aged Drug Interactions Female Humans Itraconazole therapeutic use Keratoacanthoma (...) diagnosis drug therapy pathology Sporothrix isolation & purification pathogenicity Sporotrichosis diagnosis drug therapy pathology 2012 5 5 6 0 2012 5 5 6 0 2012 6 26 6 0 ppublish 22556066 10.4269/ajtmh.2012.11-0681 PMC3335672 Indian J Dermatol Venereol Leprol. 2010 May-Jun;76(3):276-80 20445301 Curr Opin Infect Dis. 2008 Apr;21(2):129-33 18317034

2012 The American journal of tropical medicine and hygiene PubMed

86. Efficacy of posaconazole in murine experimental sporotrichosis. (Full text)

Efficacy of posaconazole in murine experimental sporotrichosis. We developed a murine model of systemic sporotrichosis by using three strains of each of the two commonest species causing sporotrichosis, i.e., Sporothrix schenckii sensu stricto and Sporothrix brasiliensis, in order to evaluate the efficacy of posaconazole (PSC). The drug was administered at a dose of 2.5 or 5 mg/kg of body weight twice a day by gavage, and one group was treated with amphotericin B (AMB) as a control treatment

2012 Antimicrobial Agents and Chemotherapy PubMed

87. Proposal of a histopathological predictive rule for the differential diagnosis between American tegumentary leishmaniasis and sporotrichosis skin lesions. (PubMed)

Proposal of a histopathological predictive rule for the differential diagnosis between American tegumentary leishmaniasis and sporotrichosis skin lesions. American tegumentary leishmaniasis (ATL) and sporotrichosis exhibit similar histopathology and low frequencies of microorganism detection.This study seeks to identify microscopic alterations that can distinguish between these diseases.Haematoxylin and eosin stained slides of 171 ATL and 97 sporotrichosis samples from active cutaneous lesions (...) by calculating kappa coefficients of the histopathological findings and intuitive diagnoses.The markers 'macrophage concentration', 'tuberculoid granuloma' and 'extracellular matrix degeneration' were associated with ATL. 'Suppurative granuloma', 'stellate granuloma', 'different types of giant cells', 'granulomas in granulation tissue' and 'abscess outside the granuloma' were associated with a diagnosis of sporotrichosis. 'Macrophage concentration' and 'suppurative granuloma' had the highest (substantial

2012 British Journal of Dermatology

88. Cutaneous Disseminated Sporotrichosis Complicated by Osteomyelitis. (Full text)

Cutaneous Disseminated Sporotrichosis Complicated by Osteomyelitis. 22855250 2013 09 24 2013 03 27 1651-2057 93 2 2013 Mar 27 Acta dermato-venereologica Acta Derm. Venereol. Cutaneous disseminated sporotrichosis complicated by osteomyelitis. 192-3 10.2340/00015555-1403 Eustace Karen E KE Sampaio Felipe M S FM Lyra Marcelo R MR Quintella Leonardo L do Valle Antonio C F AC eng Case Reports Letter Sweden Acta Derm Venereol 0370310 0001-5555 0 Antifungal Agents IM Antifungal Agents therapeutic use (...) Drainage Female Humans Osteomyelitis diagnosis microbiology therapy Sporothrix isolation & purification Sporotrichosis complications diagnosis microbiology therapy Treatment Outcome 2012 8 3 6 0 2012 8 3 6 0 2013 9 26 6 0 ppublish 22855250 10.2340/00015555-1403

2012 Acta Dermato-Venereologica PubMed

89. Sporotrichosis

Sporotrichosis Sporotrichosis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Sporotrichosis Sporotrichosis Aka: Sporotrichosis (...) fluid culture negative Culture of biopsied tissue shows saprophytic fungi VII. Management Apply warm compresses for 40 to 60 minutes per day for 2 months after lesion resolution 200 mg PO qd (preferred) ( ) 250 mg PO bid SSKI 5 drops PO tid (titrated to 40-50 drops tid) VIII. References Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Sporotrichosis." Click on the image (or right click) to open the source website in a new browser

2015 FP Notebook

90. Disseminated sporotrichosis (Full text)

Disseminated sporotrichosis Sporotrichosis is a subacute or chronic infection caused by Sporothrix schenckii. It is a primary cutaneous infection and it has different clinical forms: disseminated by lymphatic vessels (75%), localised cutaneous form (20%), disseminated cutaneous and extracuteus rarely. The systemic disseminated sporotrichosis is considered a severe opportunistic infection. The best diagnostic test is the culture. The authors report a case of a 36-year-old man, originally from (...) Puebla, Mexico, with a diagnosis of disseminated sporotrichosis. Differential diagnosis with other pathologies includes leishmaniasis, chromoblastomycosis, tuberculosis verrucose and lymphangitis. The development of unusual presentations in immunocompromised patients has been reported.

2011 BMJ case reports PubMed

91. Ultrastructural study of the mycelial phase of clinical isolates of Sporothrix schenckii obtained from feline, canine and human cases of sporotrichosis (Full text)

Ultrastructural study of the mycelial phase of clinical isolates of Sporothrix schenckii obtained from feline, canine and human cases of sporotrichosis Using transmission electron microscopy, we studied the presence of melanin and cell wall thickness of clinical isolates of Sporothrix schenckii obtained from cats, dogs and humans as compared to reference strains. We detected differences regarding presence of the melanin among the clinical isolates of S. schenckii and a correlation between

2011 Brazilian Journal of Microbiology PubMed

92. Efficacy and safety of itraconazole pulses vs. continuous regimen in cutaneous sporotrichosis. (PubMed)

Efficacy and safety of itraconazole pulses vs. continuous regimen in cutaneous sporotrichosis. Primary observation of using itraconazole pulse regimen (commonly used for onychomycosis) in five sporotrichosis patients produced satisfactory effect, but there are no randomized controlled trials to assess this regimen and to compare with routine continuous regimen.The aim of this study was to compare the efficacy and safety of itraconazole pulse regimen, as a new treatment option for cutaneous (...) sporotrichosis, with continuous regimen.A prospective, randomized, evaluator-blind, controlled study was performed. A total of 50 cutaneous sporotrichosis patients were divided randomly into two groups: Pulsed Rx (npulse=25), treated with itraconazole 200 mg b.i.d. for 1 week and off for 3 weeks; Daily Rx (ncont=25), treated with itraconazole 100 mg bid continuously. In total, 46 patients (npulse=22, ncont=24) were assessable at the end of the study. Cure rates at weeks 12, 24 and 48 along with the course

2011 Journal of the European Academy of Dermatology and Venereology : JEADV

93. Comparative study of 250 mg/day terbinafine and 100 mg/day itraconazole for the treatment of cutaneous sporotrichosis. (PubMed)

Comparative study of 250 mg/day terbinafine and 100 mg/day itraconazole for the treatment of cutaneous sporotrichosis. Itraconazole is currently used for the treatment of cutaneous sporotrichosis. Terbinafine at a daily dose of 250 mg has been successfully applied to the treatment of cutaneous sporotrichosis.To compare the efficacy of 250 mg/day terbinafine and 100 mg/day itraconazole for the treatment of cutaneous sporotrichosis.A bidirectional cohort study was conducted on 55 patients (...) for two patients of the itraconazole group.Terbinafine administered at a daily dose of 250 mg is an effective and well-tolerated option for the treatment of cutaneous sporotrichosis.

2011 Mycopathologia

94. Sporotrichosis Caused by Sporothrix mexicana, Portugal. (Full text)

Sporotrichosis Caused by Sporothrix mexicana, Portugal. 22000393 2012 02 14 2018 11 13 1080-6059 17 10 2011 Oct Emerging infectious diseases Emerging Infect. Dis. Sporotrichosis caused by Sporothrix Mexicana, Portugal. 1975-6 10.3201/eid1710.110737 Dias Nicolina Marques NM Oliveira Manoel Marques Evangelista MM Santos Cledir C Zancope-Oliveira Rosely Maria RM Lima Nelson N eng GENBANK JF970258 Case Reports Letter United States Emerg Infect Dis 9508155 1080-6040 0 Antifungal Agents 0 Calmodulin (...) IM Adult Antifungal Agents pharmacology Calmodulin genetics Genes, Fungal Humans Male Microbial Sensitivity Tests Molecular Sequence Data Portugal Sporothrix drug effects genetics isolation & purification Sporotrichosis microbiology 2011 10 18 6 0 2011 10 18 6 0 2012 2 15 6 0 ppublish 22000393 10.3201/eid1710.110737 PMC3310684 J Am Acad Dermatol. 2005 Mar;52(3 Pt 1):451-9 15761423 Clin Dermatol. 2006 May-Jun;24(3):201-12 16714201 J Clin Microbiol. 2006 Sep;44(9):3251-6 16954256 Mycopathologia

2011 Emerging Infectious Diseases PubMed

95. Animal model of human disease: sporotrichosis. (Full text)

Animal model of human disease: sporotrichosis. 831517 1977 02 26 2018 11 13 0002-9440 86 1 1977 Jan The American journal of pathology Am. J. Pathol. Animal model of human disease: sporotrichosis. 281-4 Barbee W C WC Ewert A A Davidson E M EM eng Comparative Study Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. United States Am J Pathol 0370502 0002-9440 AIM IM Animals Cats Disease Models, Animal Female Humans Male Sporotrichosis pathology 1977 1 1

1977 The American journal of pathology PubMed

96. Primary pulmonary sporotrichosis with unusual fungal morphology. (Full text)

Primary pulmonary sporotrichosis with unusual fungal morphology. Primary pulmonary sporotrichosis is a rare disease. Comstock and Wolson (1975) were able to trace approximately 30 such cases. We report a further case; to our knowledge, the various stages in the development of sporotrichosis, from a cigar body to the mature asteroid body with radiations which were present in our case, have not been so well demonstrated in a single case.

1977 Thorax PubMed

97. Lymphocutaneous nocardia Brasiliensis infection simulating sporotrichosis. (Full text)

Lymphocutaneous nocardia Brasiliensis infection simulating sporotrichosis. 906457 1977 11 25 2018 11 13 0093-0415 127 3 1977 Sep The Western journal of medicine West. J. Med. Lymphocutaneous nocardia Brasiliensis infection simulating sporotrichosis. 245-6 Belliveau R R RR Geiger F F eng Case Reports Journal Article United States West J Med 0410504 0093-0415 IM Adult Diagnosis, Differential Humans Male Nevada Nocardia isolation & purification Nocardia Infections diagnosis microbiology (...) Sporotrichosis diagnosis 1977 9 1 1977 9 1 0 1 1977 9 1 0 0 ppublish 906457 PMC1237795 South Med J. 1973 May;66(5):609-12 4698772 Am Rev Respir Dis. 1975 Nov;112(5):721-3 1190621 Am J Dis Child. 1971 Mar;121(3):246-7 5102581 Arch Dermatol. 1967 Apr;95(4):390-3 6023043 Arch Dermatol. 1966 Jan;93(1):62-4 5900706

1977 Western Journal of Medicine PubMed

98. Experimental sporotrichosis in Syrian hamsters. (Full text)

Experimental sporotrichosis in Syrian hamsters. Syrian hamsters were infected with Sporothrix schenckii by subcutaneous footpad inoculation. Two types of infection could be uniformly induced: a self-limited, lymphatic infection resembling the classical disease in humans, and a generalized nonfatal infection. An infecting dose of approximately 5,300 yeast cells produced the localized subcutaneous-lymphatic disease which was limited to a single limb. In contrast, a 1,000-fold increase (...) of infected animals, the titers persisted for at least 1 year after three booster doses of Formalin-killed S. schenckii. The ability to produce an infection in hamsters which closely resembles the disease seen in humans makes the animal a good model with which to study experimental sporotrichosis.

1979 Infection and immunity PubMed

99. Pulmonary Sporotrichosis in a Cattle Beast (Full text)

Pulmonary Sporotrichosis in a Cattle Beast 17647965 2007 07 27 2009 11 11 0316-5957 7 7 1943 Jul Canadian journal of comparative medicine and veterinary science Can J Comp Med Vet Sci Pulmonary Sporotrichosis in a Cattle Beast. 199-204 Humphreys F A FA Helmer D E DE eng Journal Article Canada Can J Comp Med Vet Sci 0151757 0316-5957 1943 7 1 0 0 1943 7 1 0 1 1943 7 1 0 0 ppublish 17647965 PMC1660706

1943 Canadian journal of comparative medicine and veterinary science PubMed

100. Sporotrichosis (Full text)

Sporotrichosis 19992646 2010 06 24 2010 06 24 0035-9157 36 6 1943 Apr Proceedings of the Royal Society of Medicine Proc. R. Soc. Med. Sporotrichosis. 297-8 Warren C M CM eng Journal Article England Proc R Soc Med 7505890 0035-9157 2009 12 9 6 0 1943 4 1 0 0 1943 4 1 0 1 ppublish 19992646 PMC1998500

1943 Proceedings of the Royal Society of Medicine PubMed

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