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Sporotrichosis

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61. Atypical Clinical Presentation of Sporotrichosis Caused by Sporothrix globosa Resistant to Itraconazole. (PubMed)

Atypical Clinical Presentation of Sporotrichosis Caused by Sporothrix globosa Resistant to Itraconazole. Sporotrichosis is a polymorphic disease of humans and animals, which is acquired via traumatic inoculation of Sporothrix propagules into cutaneous or subcutaneous tissue. The etiological agents are in a clinical complex, which includes Sporothrix brasiliensis, Sporothrix schenckii, Sporothrix globosa, and Sporothrix luriei, each of which has specific epidemiological and virulence (...) characteristics. Classical manifestation in humans includes a fixed localized lesion at the site of trauma plus lymphocutaneous sporotrichosis with fungal spreading along the lymphatic channels. Atypical sporotrichosis is a challenge to diagnosis because it can mimic many other dermatological diseases. We report an unusual, itraconazole-resistant cutaneous lesion of sporotrichosis in a 66-year-old Brazilian man. Histopathological examination of the skin revealed vascular and fibroblastic proliferation

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2016 American Journal of Tropical Medicine & Hygiene

62. Is there a relation between percentages of T helper cells and prognosis for sporotrichosis? (PubMed)

Is there a relation between percentages of T helper cells and prognosis for sporotrichosis? 26708442 2017 06 13 2017 08 17 1365-2133 174 6 2016 Jun The British journal of dermatology Br. J. Dermatol. Is there a relationship between the percentage of T helper cells and prognosis for sporotrichosis? 1398-400 10.1111/bjd.14377 Chen F F Dermatology Department, China-Japan Union Hospital of Jilin University, Changchun, Jilin, 130033, China. Yan B L BL Emergency Department, First Hospital of Jilin (...) University, Changchun, Jilin, 130021, China. An L L Dermatology Department, China-Japan Union Hospital of Jilin University, Changchun, Jilin, 130033, China. Jiang R H RH Dermatology Department, China-Japan Union Hospital of Jilin University, Changchun, Jilin, 130033, China. eng Comparative Study Letter 2016 03 20 England Br J Dermatol 0004041 0007-0963 IM Case-Control Studies Chronic Disease Female Humans Male Middle Aged Prognosis Sporotrichosis immunology T-Lymphocytes, Helper-Inducer pathology 2015 12

2015 British Journal of Dermatology

63. Genetic diversity and antifungal susceptibility profiles in causative agents of sporotrichosis. (PubMed)

Genetic diversity and antifungal susceptibility profiles in causative agents of sporotrichosis. Sporotrichosis is a chronic subcutaneous mycosis of humans and animals, which is typically acquired by traumatic inoculation of plant material contaminated with Sporothrix propagules, or via animals, mainly felines. Sporothrix infections notably occur in outbreaks, with large epidemics currently taking place in southeastern Brazil and northeastern China. Pathogenic species include Sporothrix

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2014 BMC Infectious Diseases

64. Imported lymphocutaneous sporotrichosis in Greece. (PubMed)

Imported lymphocutaneous sporotrichosis in Greece. 25421871 2016 04 12 2015 07 15 1365-2133 173 1 2015 Jul The British journal of dermatology Br. J. Dermatol. Imported lymphocutaneous sporotrichosis in Greece. 291-3 10.1111/bjd.13558 Xirotagaros G G 2nd Department of Dermatology Venereology, 'Attikon' Hospital, National and Kapodistrian University of Athens, Athens, Greece. geox74@gmail.com. Drogari-Apiranthitou M M 4th Department of Internal Medicine/Infectious Diseases Research Laboratory (...) Itraconazole therapeutic use Lymphatic Diseases drug therapy Male Molecular Sequence Data Neck Sporotrichosis drug therapy Travel Young Adult 2014 11 26 6 0 2014 11 26 6 0 2016 4 14 6 0 ppublish 25421871 10.1111/bjd.13558

2014 British Journal of Dermatology

65. In vitro and in vivo efficacy of amphotericin B combined with posaconazole against experimental disseminated sporotrichosis. (PubMed)

In vitro and in vivo efficacy of amphotericin B combined with posaconazole against experimental disseminated sporotrichosis. We evaluated the combination of posaconazole with amphotericin B in vitro and in a murine model of systemic infections caused by Sporothrix brasiliensis and Sporothrix schenckii sensu stricto. In vitro data demonstrated a synergistic effect, and although posaconazole alone was effective against sporotrichosis, efficacy in terms of survival and burden reduction (...) was increased with the combination. This combination might be an option against disseminated sporotrichosis, especially when itraconazole or amphotericin B at optimal doses are contraindicated. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

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2015 Antimicrobial Agents and Chemotherapy

66. Molecular epidemiology of human sporotrichosis in Venezuela reveals high frequency of Sporothrix globosa. (PubMed)

Molecular epidemiology of human sporotrichosis in Venezuela reveals high frequency of Sporothrix globosa. Sporotrichosis is a cutaneous and subcutaneous fungal disease of humans and other mammals, known to be caused by the Sporothrix schenckii species complex, which comprises four species of clinical importance: S. brasiliensis, S. globosa, S. luriei, and S. schenckii sensu stricto. Of them, S. globosa and S. schenckii s. str. show global distribution and differences in global frequency (...) as causal agents of the disease. In the Americas, only three species are present: S. schenckii s. str., S. brasiliensis (so far, only reported in Brazil), and S. globosa. In Venezuela, since the first case of sporotrichosis reported in 1935, S. schenckii have been considered its unique etiological agent. In the present work, the presence of more than one species in the country was evaluated.By phenotypic key features and molecular phylogeny analyses, we re-examined 30 isolates from diverse Venezuelan

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2015 BMC Infectious Diseases

67. Sporotrichosis: The Story of an Endemic Region in Peru over 28 Years (1985 to 2012) (PubMed)

Sporotrichosis: The Story of an Endemic Region in Peru over 28 Years (1985 to 2012) Abancay province is a long-standing geographical focus of sporotrichosis in the south central highlands of Peru. Therefore, we examined the features of 36 newly identified cases of sporotrichosis from two hospital centers in Abancay province. We also performed a literature review of studies conducted in this endemic geographical focus over a period of 28 years (1998 to 2012), and analyzed the demographic (...) , clinical and epidemiological features of sporotrichosis in the cases reported in these studies.We examined the features of 36 new cases of sporotrichosis identified from two hospital centers in Abancay. Furthermore, we searched for relevant studies of cases of sporotrichosis in the endemic region using healthcare databases and literature sources. We analyzed a detailed subset of data on cases collected in Abancay, neighboring provinces, and other regions of Peru.A total of nine studies were identified

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2015 PloS one

68. Sporotrichosis (Treatment)

Sporotrichosis (Treatment) Dermatologic Manifestations of Sporotrichosis Treatment & Management: Medical Care, Surgical Care, Consultations Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA5MTE1OS10cmVhdG1lbnQ (...) = processing > Dermatologic Manifestations of Sporotrichosis Treatment & Management Updated: May 17, 2016 Author: Scott D Miller, MD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Dermatologic Manifestations of Sporotrichosis Treatment Medical Care Systemic antifungal agents are the mainstay of treatment. Antifungal agents are used for fungicidal or fungistatic eradication of the infective organism S schenkii . [ , ] An increase in cutaneous induration, redness

2014 eMedicine.com

69. Sporotrichosis (Treatment)

Sporotrichosis (Treatment) Sporotrichosis Treatment & Management: Medical Care, Surgical Care, Activity Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjI4NzIzLXRyZWF0bWVudA== processing > Sporotrichosis Treatment (...) & Management Updated: Sep 07, 2018 Author: Nelson Ivan Agudelo Higuita, MD; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD Share Email Print Feedback Close Sections Sections Sporotrichosis Treatment Medical Care Antifungal therapy is the mainstay of treatment for all forms of sporotrichosis. Next: Surgical Care Surgical therapy is important in the management of osteoarticular sporotrichosis. Principles of surgical care are the same as for other bone and joint infections. Appropriate drainage

2014 eMedicine.com

70. Sporotrichosis (Overview)

Sporotrichosis (Overview) Sporotrichosis: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjI4NzIzLW92ZXJ2aWV3 processing > Sporotrichosis Updated: Sep 07, 2018 Author (...) : Nelson Ivan Agudelo Higuita, MD; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD Share Email Print Feedback Close Sections Sections Sporotrichosis Overview Background Sporotrichosis, also known as rose gardener's disease, is a subacute or chronic infection caused by the saprophytic dimorphic fungus Sporothrix schenckii . Although only one species of Sporothrix was classically described, phenetic and genetic studies have identified additional Sporothrix species. [ ] Knowledge of the geographic

2014 eMedicine.com

71. Sporotrichosis (Overview)

Sporotrichosis (Overview) Dermatologic Manifestations of Sporotrichosis: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA5MTE1OS1vdmVydmlldw== processing > Dermatologic (...) Manifestations of Sporotrichosis Updated: May 17, 2016 Author: Scott D Miller, MD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Dermatologic Manifestations of Sporotrichosis Overview Background Sporotrichosis is a subcutaneous or systemic infection caused by Sporothrix schenckii , a rapidly growing dimorphic fungus. The organism derives its name from R B Schenck, who first reported the infection in 1898. Sporothrix species typically exist as a saprophytic mold

2014 eMedicine.com

72. Sporotrichosis (Follow-up)

Sporotrichosis (Follow-up) Sporotrichosis Follow-up: Further Outpatient Care, Deterrence/Prevention, Prognosis Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjI4NzIzLWZvbGxvd3Vw processing > Sporotrichosis Follow (...) -up Updated: Sep 07, 2018 Author: Nelson Ivan Agudelo Higuita, MD; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD Share Email Print Feedback Close Sections Sections Sporotrichosis Follow-up Further Outpatient Care S schenckii strains that cause cutaneous or lymphocutaneous sporotrichosis grow better at 35°C than at 37°C; therefore, topical heat application to lesions may be of adjunctive benefit. Next: Deterrence/Prevention Exercise efforts to minimize cutaneous inoculation of S schenckii

2014 eMedicine.com

73. Sporotrichosis (Follow-up)

Sporotrichosis (Follow-up) Dermatologic Manifestations of Sporotrichosis Treatment & Management: Medical Care, Surgical Care, Consultations Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA5MTE1OS10cmVhdG1lbnQ (...) = processing > Dermatologic Manifestations of Sporotrichosis Treatment & Management Updated: May 17, 2016 Author: Scott D Miller, MD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Dermatologic Manifestations of Sporotrichosis Treatment Medical Care Systemic antifungal agents are the mainstay of treatment. Antifungal agents are used for fungicidal or fungistatic eradication of the infective organism S schenkii . [ , ] An increase in cutaneous induration, redness

2014 eMedicine.com

74. Sporotrichosis (Diagnosis)

Sporotrichosis (Diagnosis) Pediatric Sporotrichosis: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvOTY4OTAyLW92ZXJ2aWV3 processing > Pediatric Sporotrichosis Updated: Feb (...) 12, 2019 Author: William P Baugh, MD; Chief Editor: Russell W Steele, MD Share Email Print Feedback Close Sections Sections Pediatric Sporotrichosis Overview Background Sporotrichosis is caused by the acquisition of Sporothrix schenckii , a dimorphic, saprophytic, and geophilic fungus. Although this fungal infection has been reported in semiarid environments, it is most typically found in warmer temperatures and tropical climates around the world. [ ] S schenckii usually grows amidst decaying

2014 eMedicine Pediatrics

75. Sporotrichosis (Overview)

Sporotrichosis (Overview) Pediatric Sporotrichosis: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvOTY4OTAyLW92ZXJ2aWV3 processing > Pediatric Sporotrichosis Updated: Feb (...) 12, 2019 Author: William P Baugh, MD; Chief Editor: Russell W Steele, MD Share Email Print Feedback Close Sections Sections Pediatric Sporotrichosis Overview Background Sporotrichosis is caused by the acquisition of Sporothrix schenckii , a dimorphic, saprophytic, and geophilic fungus. Although this fungal infection has been reported in semiarid environments, it is most typically found in warmer temperatures and tropical climates around the world. [ ] S schenckii usually grows amidst decaying

2014 eMedicine Pediatrics

76. Sporotrichosis (Follow-up)

Sporotrichosis (Follow-up) Pediatric Sporotrichosis Follow-up: Further Outpatient Care, Further Inpatient Care, Inpatient & Outpatient Medications Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvOTY4OTAyLWZvbGxvd3Vw processing > Pediatric Sporotrichosis Follow-up Updated: Feb 12, 2019 Author: William P Baugh, MD; Chief Editor: Russell W Steele, MD Share Email Print Feedback Close Sections Sections Pediatric Sporotrichosis Follow-up Further Outpatient Care See the list below: The primary therapeutic approach to managing cutaneous lesions of sporotrichosis involves administration of systemic medications to eradicate the fungus. If a cutaneous plaque, nodule, or ulcer is present, consider teaching

2014 eMedicine Pediatrics

77. Sporotrichosis (Treatment)

Sporotrichosis (Treatment) Pediatric Sporotrichosis Treatment & Management: Medical Care, Consultations, Activity Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvOTY4OTAyLXRyZWF0bWVudA== processing > Pediatric (...) Sporotrichosis Treatment & Management Updated: Feb 12, 2019 Author: William P Baugh, MD; Chief Editor: Russell W Steele, MD Share Email Print Feedback Close Sections Sections Pediatric Sporotrichosis Treatment Medical Care Medical therapy is the standard of care for sporotrichosis. Patients are commonly treated with an oral antifungal agent on an outpatient basis. Surgical therapy, other than to perform a biopsy from a lesion for establishing the diagnosis, is rarely used as a form of treatment. Aggressive

2014 eMedicine Pediatrics

78. Sporotrichosis (Diagnosis)

Sporotrichosis (Diagnosis) Sporotrichosis: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjI4NzIzLW92ZXJ2aWV3 processing > Sporotrichosis Updated: Sep 07, 2018 Author (...) : Nelson Ivan Agudelo Higuita, MD; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD Share Email Print Feedback Close Sections Sections Sporotrichosis Overview Background Sporotrichosis, also known as rose gardener's disease, is a subacute or chronic infection caused by the saprophytic dimorphic fungus Sporothrix schenckii . Although only one species of Sporothrix was classically described, phenetic and genetic studies have identified additional Sporothrix species. [ ] Knowledge of the geographic

2014 eMedicine.com

79. Sporotrichosis (Diagnosis)

Sporotrichosis (Diagnosis) Dermatologic Manifestations of Sporotrichosis: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA5MTE1OS1vdmVydmlldw== processing > Dermatologic (...) Manifestations of Sporotrichosis Updated: May 17, 2016 Author: Scott D Miller, MD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Dermatologic Manifestations of Sporotrichosis Overview Background Sporotrichosis is a subcutaneous or systemic infection caused by Sporothrix schenckii , a rapidly growing dimorphic fungus. The organism derives its name from R B Schenck, who first reported the infection in 1898. Sporothrix species typically exist as a saprophytic mold

2014 eMedicine.com

80. Oral potassium iodide for the treatment of sporotrichosis. (PubMed)

Oral potassium iodide for the treatment of sporotrichosis. Sporotrichosis is a subacute or chronic disease, usually affecting the skin caused by a dimorphic (existing in two forms), aerobic (oxygen requiring) fungus called Sporothrix schenckii. Oral potassium iodide is widely used for cutaneous sporotrichosis in clinical medicine with more and more reports published. However, the benefits and adverse reactions of these treatments have not yet been systematically reviewed.To assess the effects (...) for or against oral potassium iodide as a treatment for sporotrichosis. Further randomised double-blind placebo-controlled trials are needed to define the efficacy and acceptability of these interventions.

2009 Cochrane

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