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Sporotrichosis

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41. Zoonotic Epidemic of Sporotrichosis: Cat to Human Transmission (PubMed)

Zoonotic Epidemic of Sporotrichosis: Cat to Human Transmission 28103311 2018 01 02 2019 02 02 1553-7374 13 1 2017 01 PLoS pathogens PLoS Pathog. Zoonotic Epidemic of Sporotrichosis: Cat to Human Transmission. e1006077 10.1371/journal.ppat.1006077 Gremião Isabella Dib Ferreira ID Laboratory of Clinical Research on Dermatozoonosis in Domestic Animals, Evandro Chagas National Institute of Infectious Diseases, Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil. Miranda Luisa (...) Cats Epidemics Humans Sporotrichosis epidemiology transmission Zoonoses epidemiology transmission The authors have declared that no competing interests exist. 2017 1 20 6 0 2017 1 20 6 0 2018 1 3 6 0 epublish 28103311 10.1371/journal.ppat.1006077 PPATHOGENS-D-16-01061 PMC5245785 Cad Saude Publica. 2012 Oct;28(10):1867-80 23090167 Clin Infect Dis. 1993 Mar;16(3):384-7 8095815 Med Mycol. 2008 Feb;46(1):53-6 17885948 Int J Dermatol. 2009 Nov;48(11):1198-200 20064175 Biomed Res Int. 2015;2015:212308

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2017 PLoS pathogens

42. Rapidly Progressive Disseminated Sporotrichosis as the First Presentation of HIV Infection in a Patient with a Very Low CD4 Cell Count (PubMed)

Rapidly Progressive Disseminated Sporotrichosis as the First Presentation of HIV Infection in a Patient with a Very Low CD4 Cell Count Sporotrichosis is a human and animal disease caused by species of the Sporothrix schenckii complex. It is classically acquired through traumatic inoculation of fungal elements. Most frequently, sporotrichosis presents as a fixed cutaneous or as a lymphocutaneous form. A much smaller number of cases occur as cutaneous disseminated and disseminated forms (...) . These cases require immediate diagnosis and management to reduce morbidity and mortality. We present the case of a 34-year-old male patient in whom the first presentation of HIV infection was a rapidly progressive sporotrichosis with multiple cutaneous lesions, a high fungal burden in tissues, and pulmonary involvement. He had an extremely low CD4 cell count (06/mm3). Treatment with amphotericin B deoxycholate led to complete clinical resolution. Sporotrichosis remains a neglected opportunistic infection

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2017 Case reports in infectious diseases

43. Sporotrichosis in a liver transplant patient: A case report and literature review (PubMed)

Sporotrichosis in a liver transplant patient: A case report and literature review The liver transplant patient was admitted to the hospital with hyperemic, granulomatous, ulcerated lesion in the anterior compartment of the right lower limb with report of local trauma. The agent Sporothrix schenckii was isolated from biopsy of the lesion and lymph nodes of the right lower limb. In this case, the treatment was difficult because the patient has severe pulmonary hypertension and took the following

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2017 Medical mycology case reports

44. Sporotrichosis by Sporothrix schenckii senso stricto with itraconazole resistance and terbinafine sensitivity observed in vitro and in vivo: Case report (PubMed)

Sporotrichosis by Sporothrix schenckii senso stricto with itraconazole resistance and terbinafine sensitivity observed in vitro and in vivo: Case report We report a case of a patient with lymphocutaneous sporotrichosis in the right upper limb. The fungus was identified as Sporothrix schenckii senso stricto by calmodulin gene sequencing. The initial treatment was itraconazole (200 mg/day), but in vitro antifungal susceptibility demonstrated high resistant to this and another six antifungals

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2017 Medical mycology case reports

45. Cutaneous Sporotrichosis Presenting as Clinical Feature of Facial Cellulitis in an Adult (PubMed)

Cutaneous Sporotrichosis Presenting as Clinical Feature of Facial Cellulitis in an Adult 27489440 2016 08 04 2018 11 13 1013-9087 28 4 2016 Aug Annals of dermatology Ann Dermatol Cutaneous Sporotrichosis Presenting as Clinical Feature of Facial Cellulitis in an Adult. 507-8 10.5021/ad.2016.28.4.507 Song Jun Gyu JG Department of Dermatology, Dongguk University College of Medicine, Gyeongju, Korea. Song You Bum YB Department of Dermatology, Dongguk University College of Medicine, Gyeongju, Korea

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2016 Annals of dermatology

46. Chromoblastomycosis due to Fonsecaea monophora misdiagnosed as sporotrichosis and cutaneous tuberculosis in a pulmonary tuberculosis patient (PubMed)

Chromoblastomycosis due to Fonsecaea monophora misdiagnosed as sporotrichosis and cutaneous tuberculosis in a pulmonary tuberculosis patient Chromoblastomycosis is caused by dematiaceous fungi. It develops after inoculation of the organism into the skin. We report a case of chromoblastomycosis in a pulmonary tuberculosis patient without known history of trauma. The lesions were initially diagnosed as sporotrichosis and skin tuberculosis. Histopathology of scales and skin biopsy specimen

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2016 Medical mycology case reports

47. Sporotrichosis-Associated Hospitalizations, United States, 2000-2013. (PubMed)

Sporotrichosis-Associated Hospitalizations, United States, 2000-2013. To determine frequency and risk for sporotrichosis-associated hospitalizations, we analyzed the US 2000-2013 National (Nationwide) Inpatient Sample. An estimated 1,471 hospitalizations occurred (average annual rate 0.35/1 million persons). Hospitalizations were associated with HIV/AIDS, immune-mediated inflammatory diseases, and chronic obstructive pulmonary disease. Although rare, severe sporotrichosis should be considered

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2016 Emerging Infectious Diseases

48. Atypical Clinical Presentation of Sporotrichosis Caused by Sporothrix globosa Resistant to Itraconazole. (PubMed)

Atypical Clinical Presentation of Sporotrichosis Caused by Sporothrix globosa Resistant to Itraconazole. Sporotrichosis is a polymorphic disease of humans and animals, which is acquired via traumatic inoculation of Sporothrix propagules into cutaneous or subcutaneous tissue. The etiological agents are in a clinical complex, which includes Sporothrix brasiliensis, Sporothrix schenckii, Sporothrix globosa, and Sporothrix luriei, each of which has specific epidemiological and virulence (...) characteristics. Classical manifestation in humans includes a fixed localized lesion at the site of trauma plus lymphocutaneous sporotrichosis with fungal spreading along the lymphatic channels. Atypical sporotrichosis is a challenge to diagnosis because it can mimic many other dermatological diseases. We report an unusual, itraconazole-resistant cutaneous lesion of sporotrichosis in a 66-year-old Brazilian man. Histopathological examination of the skin revealed vascular and fibroblastic proliferation

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2016 American Journal of Tropical Medicine & Hygiene

49. Sporotrichosis of Maxillary Sinuses in a Middle Aged Female Patient from Rural Area of Eastern India (PubMed)

Sporotrichosis of Maxillary Sinuses in a Middle Aged Female Patient from Rural Area of Eastern India Sporotrichosis is commonly a chronic infection caused by Sporothrix schenckii, a saprophytic fungus and is usually limited to cutaneous and subcutaneous tissues. Disseminated systemic, osteoarticular or pulmonary sporotrichosis have been reported but nasal sinusitis by this fungus is extremely infrequent. Earlier report from southern India documented a case of maxillary sinusitis by Sporothrix

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2016 Journal of clinical and diagnostic research : JCDR

50. Draft Genome Sequence of the Dimorphic Fungus Sporothrix pallida, a Nonpathogenic Species Belonging to Sporothrix, a Genus Containing Agents of Human and Feline Sporotrichosis (PubMed)

Draft Genome Sequence of the Dimorphic Fungus Sporothrix pallida, a Nonpathogenic Species Belonging to Sporothrix, a Genus Containing Agents of Human and Feline Sporotrichosis Sporothrix pallidais considered to be a mostly avirulent environmental fungus, phylogenetically closely related to the well-known pathogenSporothrix schenckii Here, we present the first assembly of its genome, which provides a valuable resource for future comparative genomic studies between nonpathogenic

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2016 Genome Announcements

51. A Case of Sporotrichosis Caused by Sporothrix globosa in Japan (PubMed)

A Case of Sporotrichosis Caused by Sporothrix globosa in Japan 27081278 2016 04 15 2018 11 13 1013-9087 28 2 2016 Apr Annals of dermatology Ann Dermatol A Case of Sporotrichosis Caused by Sporothrix globosa in Japan. 251-2 10.5021/ad.2016.28.2.251 Watanabe Mana M Division of Cutaneous Science, Department of Dermatology, Nihon University School of Medicine, Tokyo, Japan. Hayama Koremasa K Division of Cutaneous Science, Department of Dermatology, Nihon University School of Medicine, Tokyo, Japan

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2016 Annals of dermatology

52. Sporotrichosis as an unusual case of osteomyelitis: A case report and review of the literature (PubMed)

Sporotrichosis as an unusual case of osteomyelitis: A case report and review of the literature Sporotrichosis is an infection of worldwide distribution caused by the dimorphic fungus, Sporothrix schenckii. Acquisition typically occurs via cutaneous inoculation with development of a localized cutaneous and/or lymphocutaneous infection. We present a rare case of osteoarticular sporotrichosis in a 39-year-old man and review the literature noting only 20 published cases since 1980. Recommendations

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2016 Medical mycology case reports

53. Sporotrichosis

Sporotrichosis Sporotrichosis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Sporotrichosis Sporotrichosis Aka: Sporotrichosis (...) fluid culture negative Culture of biopsied tissue shows saprophytic fungi VII. Management Apply warm compresses for 40 to 60 minutes per day for 2 months after lesion resolution 200 mg PO qd (preferred) ( ) 250 mg PO bid SSKI 5 drops PO tid (titrated to 40-50 drops tid) VIII. References Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Sporotrichosis." Click on the image (or right click) to open the source website in a new browser

2018 FP Notebook

54. Epidemiological investigation of an outbreak of cutaneous sporotrichosis, Northern Territory, Australia. (PubMed)

Epidemiological investigation of an outbreak of cutaneous sporotrichosis, Northern Territory, Australia. An outbreak of cutaneous sporotrichosis occurred in the Darwin region of the Northern Territory (NT) in 2014. We aimed to determine the source and risk factors associated with the outbreak and describe the clinical spectrum of cases seen.Epidemiological investigation of cases of cutaneous sporotrichosis identified through the Royal Darwin Hospital was undertaken to investigate risk factors (...) and potential sources of infection. Data were collected through chart review and individual patient interviews. Environmental investigation followed identification of a common risk factor.Nine confirmed cases of cutaneous sporotrichosis caused by Sporothrix schenckii were identified with onset of symptoms between April and July 2014. Patients were aged 29 to 70 years and seven were male (78%). Two strains of S. schenckii were identified, neither of which have been previously documented. One common risk

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2016 BMC Infectious Diseases

55. A 27-Year-Old Severely Immunosuppressed Female with Misleading Clinical Features of Disseminated Cutaneous Sporotrichosis (PubMed)

A 27-Year-Old Severely Immunosuppressed Female with Misleading Clinical Features of Disseminated Cutaneous Sporotrichosis Sporotrichosis is a subacute or chronic granulomatous mycosis caused by fungus of the Sporothrix schenckii complex. It is considered to be a rare condition in most parts of the world. It mostly causes cutaneous infection but can also cause multisystemic disease. Unlike most deep cutaneous mycoses which have a primary pulmonary focus, it is usually caused by direct (...) inoculation of the fungus into the skin causing a classical linear, lymphocutaneous nodular eruption. However, atypical presentations of the condition can occur especially in immunosuppressed individuals. We report the case of a severely immunosuppressed female who presented with disseminated cutaneous sporotrichosis which was initially diagnosed and treated as disseminated cutaneous Kaposi's sarcoma.

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2016 Case reports in dermatological medicine

56. Disseminated sporotrichosis in an immunocompetent patient (PubMed)

Disseminated sporotrichosis in an immunocompetent patient Sporothrix schenckii, the causative agent of sporotrichosis, is a relatively rare infection. Local infection usually occurs through direct inoculation of the organism through the skin; disseminated disease is rarely seen. This article describes a case of disseminated sporotrichosis in a middle-aged man without the commonly seen risk factors for dissemination.

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2016 Case Reports in Plastic Surgery & Hand Surgery

57. Immune Response Induced by an Immunodominant 60 kDa Glycoprotein of the Cell Wall of Sporothrix schenckii in Two Mice Strains with Experimental Sporotrichosis (PubMed)

Immune Response Induced by an Immunodominant 60 kDa Glycoprotein of the Cell Wall of Sporothrix schenckii in Two Mice Strains with Experimental Sporotrichosis Cell wall (CW) components of fungus Sporothrix schenckii are the major inductors antigens of immune responses. The immunodominant 60 kDa glycoprotein (gp60) has been shown to be associated with the virulence of this fungus but its role in experimental sporotrichosis is unknown. In this work, the immunological effects of CW-purified gp60 (...) were investigated in a model of experimental subcutaneous sporotrichosis in normal and gp60-preimmunized C57BL/6 and BALB/c mice strains which were then infected with S. schenckii conidia. Results showed that both mice strains use different cytokine profiles in order to fight S. schenckii infection; C57BL/6 mice seem to use a Th17 response while BALB/c mice tend to depend on a Th1 profile. Preimmunization with gp60 showed a downregulatory effect on the immune response since cytokines levels were

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2016 Journal of immunology research

58. Oral potassium iodide for the treatment of sporotrichosis. (PubMed)

Oral potassium iodide for the treatment of sporotrichosis. Sporotrichosis is a subacute or chronic disease, usually affecting the skin caused by a dimorphic (existing in two forms), aerobic (oxygen requiring) fungus called Sporothrix schenckii. Oral potassium iodide is widely used for cutaneous sporotrichosis in clinical medicine with more and more reports published. However, the benefits and adverse reactions of these treatments have not yet been systematically reviewed.To assess the effects (...) for or against oral potassium iodide as a treatment for sporotrichosis. Further randomised double-blind placebo-controlled trials are needed to define the efficacy and acceptability of these interventions.

2009 Cochrane

59. The accuracy of serological tests using recombinant antigens for diagnosis of sporotrichosis: a systematic review and meta-analysis

The accuracy of serological tests using recombinant antigens for diagnosis of sporotrichosis: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne

2018 PROSPERO

60. Is there a relation between percentages of T helper cells and prognosis for sporotrichosis? (PubMed)

Is there a relation between percentages of T helper cells and prognosis for sporotrichosis? 26708442 2017 06 13 2017 08 17 1365-2133 174 6 2016 Jun The British journal of dermatology Br. J. Dermatol. Is there a relationship between the percentage of T helper cells and prognosis for sporotrichosis? 1398-400 10.1111/bjd.14377 Chen F F Dermatology Department, China-Japan Union Hospital of Jilin University, Changchun, Jilin, 130033, China. Yan B L BL Emergency Department, First Hospital of Jilin (...) University, Changchun, Jilin, 130021, China. An L L Dermatology Department, China-Japan Union Hospital of Jilin University, Changchun, Jilin, 130033, China. Jiang R H RH Dermatology Department, China-Japan Union Hospital of Jilin University, Changchun, Jilin, 130033, China. eng Comparative Study Letter 2016 03 20 England Br J Dermatol 0004041 0007-0963 IM Case-Control Studies Chronic Disease Female Humans Male Middle Aged Prognosis Sporotrichosis immunology T-Lymphocytes, Helper-Inducer pathology 2015 12

2015 British Journal of Dermatology

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