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Sporotrichosis

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21. Sporotrichin Skin Test for the Diagnosis of Sporotrichosis Full Text available with Trip Pro

Sporotrichin Skin Test for the Diagnosis of Sporotrichosis Sporotrichosis is the most common implantation mycosis caused by several species of the Sporothrix schenckii complex. The gold standard for diagnosis is concerned with the isolation of the fungus; although, fresh examinations, staining, and biopsies are also helpful for this purpose. The sporotrichin is an antigenic complex comprised of a peptide-rhamnomannan, which is relevant with respect to pathogenic fungi; it is primarily used (...) for serological and skin testing. We present a study regarding the use of sporotrichin as a diagnostic aid for cutaneous sporotrichosis. Furthermore, 138 cases with suspicion of sporotrichosis were included, 55 of which were proven through cultures. Moreover, out of these 55 cases, 52 (94.5%) tested positive for sporotrichin, while the negative cases corresponded to the disseminated cutaneous forms. We observed a sensitivity of 94.5% and a specificity of 95.2%. We consider that the use of sporotrichin

2018 Journal of Fungi

22. Feline sporotrichosis: associations between clinical-epidemiological profiles and phenotypic-genotypic characteristics of the etiological agents in the Rio de Janeiro epizootic area Full Text available with Trip Pro

Feline sporotrichosis: associations between clinical-epidemiological profiles and phenotypic-genotypic characteristics of the etiological agents in the Rio de Janeiro epizootic area Sporotrichosis is caused by species of the genus Sporothrix. From 1998 to 2015, 4,703 cats were diagnosed at the Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Brazil. Even after the description of the Sporothrix species, the characterisation of feline isolates is not performed routinely.To characterise (...) of the species.In phenotypic tests, 34 isolates were characterised as S. brasiliensis, one as S. schenckii and 12 as Sporothrix spp. PCR identified all isolates as S. brasiliensis.S. brasiliensis is the only etiological agent of feline sporotrichosis in Rio de Janeiro to date. None association was found between the isolates and the clinical and epidemiological data. In addition, we strongly recommend the use of molecular techniques for the identification of isolates of Sporothrix spp.

2018 Memórias do Instituto Oswaldo Cruz

23. Sporotrichosis: From KOH to Molecular Biology Full Text available with Trip Pro

Sporotrichosis: From KOH to Molecular Biology Sporotrichosis is a cosmopolitan, chronic granulomatous mycosis, acquired by traumatic inoculation and caused by Sporothrix schenckii complex. Several methods of diagnostic are available, from KOH to molecular biology. In this review, we describe from the simplest (clinical diagnosis) to the most advanced diagnostic techniques (molecular biology).

2018 Journal of Fungi

24. The Infection Returns: A Case of Pulmonary Sporotrichosis Relapse after Chemotherapy Full Text available with Trip Pro

The Infection Returns: A Case of Pulmonary Sporotrichosis Relapse after Chemotherapy Pulmonary sporotrichosis is a rare disease caused by a dimorphic fungus, Sporothrix schenckii. It is rarely found in association with malignancy. We present a case of pulmonary sporotrichosis recurrence after chemotherapy.A 44-year-old man, treated for pulmonary sporotrichosis in the past, presented with dysphagia and was found to have squamous cell carcinoma of the esophagus. After undergoing chemotherapy

2018 Case reports in medicine

25. An immunoproteomic approach revealing peptides from Sporothrix brasiliensis that induce a cellular immune response in subcutaneous sporotrichosis Full Text available with Trip Pro

An immunoproteomic approach revealing peptides from Sporothrix brasiliensis that induce a cellular immune response in subcutaneous sporotrichosis Sporothrix brasiliensis is the most virulent fungus of the Sporothrix complex and is the main species recovered in the sporotrichosis zoonotic hyperendemic area in Rio de Janeiro. A vaccine against S. brasiliensis could improve the current sporotrichosis situation. Here, we show 3 peptides from S. brasiliensis immunogenic proteins that have a higher (...) likelihood for engaging MHC-class II molecules. We investigated the efficiency of the peptides as vaccines for preventing subcutaneous sporotrichosis. In this study, we observed a decrease in lesion diameters in peptide-immunized mice, showing that the peptides could induce a protective immune response against subcutaneous sporotrichosis. ZR8 peptide is from the GP70 protein, the main antigen of the Sporothrix complex, and was the best potential vaccine candidate by increasing CD4+ T cells and higher

2018 Scientific reports

26. A case of disseminated sporotrichosis caused by Sporothrix brasiliensis Full Text available with Trip Pro

A case of disseminated sporotrichosis caused by Sporothrix brasiliensis This paper presents a case of disseminated sporotrichosis in a 13-year-old female, originating from a rural area in Minas Gerais state, Brazil. The patient was hospitalized in Santa Casa hospital of Belo Horizonte, with hyporexia, prostration, fever and disseminated ulcerative lesions, besides anemia, leucopenia and sepsis of probable cutaneous focus. The patient was admitted without proven immunosuppression. She (...) was diagnosed with cutaneous-disseminated sporotrichosis. The drug therapy chosen was itraconazole during 12 months, leading to important clinical improvement and healing of cutaneous lesions.

2018 Medical mycology case reports

27. Unbalanced inflammatory reaction could increase tissue destruction and worsen skin infectious diseases – a comparative study of leishmaniasis and sporotrichosis Full Text available with Trip Pro

Unbalanced inflammatory reaction could increase tissue destruction and worsen skin infectious diseases – a comparative study of leishmaniasis and sporotrichosis The clinical presentations of skin diseases produced by different pathogens, as American tegumentary leishmaniasis (ATL) and sporotrichosis can be similar and possibly influenced by the skin immune system (SIS). The aim of the study was to understand the underlying mechanisms of skin inflammation produced by different pathogens. We (...) used immunohistochemistry to analyze 96 patients: a- localized cutaneous leishmaniasis (LCL-ATL); b- sporotrichoid cutaneous leishmaniasis (SCL-ATL); c-lymphocutaneous (LC-SP); d- fixed (F-SP) sporotrichosis. LCL-ATL and SCL-ATL had a significantly higher percentage of CD8, FasL and NOS2 than sporotrichosis. In contrast, LC-SP had a substantially higher percentage of CD4, BCl2 and neutrophils than ATL lesions. These results indicated some differences in the profile of the in situ immune response

2018 Scientific reports

28. The role of dermoscopy in the diagnosis of deep mycoses and systemic mycoses with cutaneous involvement Comment on "Dermoscopy in disseminated sporotrichosis". Full Text available with Trip Pro

The role of dermoscopy in the diagnosis of deep mycoses and systemic mycoses with cutaneous involvement Comment on "Dermoscopy in disseminated sporotrichosis". 29953679 2019 01 18 1468-3083 33 1 2019 Jan Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol The role of dermoscopy in the diagnosis of deep mycoses and systemic mycoses with cutaneous involvement: Comment on 'Dermoscopy in disseminated sporotrichosis'. e35-e36 10.1111/jdv.15155

2018 Journal of the European Academy of Dermatology and Venereology

29. Dermoscopy in disseminated sporotrichosis. Full Text available with Trip Pro

Dermoscopy in disseminated sporotrichosis. 29953691 2019 01 18 1468-3083 33 1 2019 Jan Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol Dermoscopy in disseminated sporotrichosis. e33-e35 10.1111/jdv.15152 Dabas G G http://orcid.org/0000-0001-8675-2825 Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. Kaur H H Department of Medical Microbiology

2018 Journal of the European Academy of Dermatology and Venereology

30. Sporotrichosis in the nail—An unusual location and presentation Full Text available with Trip Pro

Sporotrichosis in the nail—An unusual location and presentation 29387746 2019 02 26 2352-5126 4 1 2018 Jan JAAD case reports JAAD Case Rep Sporotrichosis in the nail-An unusual location and presentation. 47-49 10.1016/j.jdcr.2017.08.003 Larson Krista N KN Department of Dermatology, West Virginia University, Morgantown, West Virginia. Pandey Shaily S Department of Dermatology, University of North Carolina, Chapel Hill, North Carolina. Hoover William W 3rd Department of Dermatology, University (...) of North Carolina, Chapel Hill, North Carolina. Sun Natalie Z NZ Department of Dermatology, University of North Carolina, Chapel Hill, North Carolina. eng Case Reports 2017 12 19 United States JAAD Case Rep 101665210 2352-5126 fungus nail disorders sporotrichosis 2018 2 2 6 0 2018 2 2 6 0 2018 2 2 6 1 epublish 29387746 10.1016/j.jdcr.2017.08.003 S2352-5126(17)30184-4 PMC5771738 Ann Dermatol. 2016 Apr;28(2):251-2 27081278 Indian J Dermatol. 2013 Sep;58(5):409 24082217 J Am Acad Dermatol. 2012 May;66(5

2017 JAAD Case Reports

31. Cutaneous disseminated sporotrichosis: Clinical experience of 24 cases. (Abstract)

Cutaneous disseminated sporotrichosis: Clinical experience of 24 cases. 28833587 2018 02 21 1468-3083 32 2 2018 Feb Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol Cutaneous disseminated sporotrichosis: clinical experience of 24 cases. e77-e79 10.1111/jdv.14533 Bonifaz A A Dermatology Service & Mycology Department, Hospital General de México, "Dr. Eduardo Liceaga", Mexico City, Mexico. Tirado-Sánchez A A Dermatology Service & Mycology

2017 Journal of the European Academy of Dermatology and Venereology

32. Cutaneous sporotrichosis treated with methylene blue-daylight photodynamic therapy. (Abstract)

Cutaneous sporotrichosis treated with methylene blue-daylight photodynamic therapy. 28846164 2018 03 14 1468-3083 32 3 2018 Mar Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol Cutaneous sporotrichosis treated with methylene blue-daylight photodynamic therapy. e90-e91 10.1111/jdv.14545 García-Malinis A J AJ Unit of Dermatology, San Jorge Hospital, Avenida Martinez de Velasco, 36, Huesca, Spain. Unit of Dermatology, Jaca Hospital, Avenida

2017 Journal of the European Academy of Dermatology and Venereology

33. Sporotrichosis transmitted by a cockatiel (Nymphicus hollandicus). (Abstract)

Sporotrichosis transmitted by a cockatiel (Nymphicus hollandicus). 29080316 2018 03 25 1468-3083 32 4 2018 Apr Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol Sporotrichosis transmitted by a cockatiel (Nymphicus hollandicus). e157-e158 10.1111/jdv.14661 Fichman V V http://orcid.org/0000-0003-0348-8008 Laboratory of Clinical Research on Infectious Dermatology, Evandro Chagas National Institute of Infectious Diseases, Oswaldo Cruz Foundation

2017 Journal of the European Academy of Dermatology and Venereology

34. Sporotrichosis among children of a hyperendemic area in Peru: an 8-year retrospective study. (Abstract)

Sporotrichosis among children of a hyperendemic area in Peru: an 8-year retrospective study. The clinical and epidemiologic characteristics of pediatric sporotrichosis are poorly understood.To describe the incidence and clinical characteristics of cases of sporotrichosis in children 14 years of age and younger reported in Abancay from 2004 to 2011, stratified according to age.We performed a retrospective review of pediatric patients 14 years of age and younger who were diagnosed (...) with sporotrichosis in a referral center at Abancay, a poor area located in the south central highlands of Peru, to estimate the incidence rates (per 100,000 person-years) according to age and sporotrichosis type (lymphocutaneous and fixed), and clinical characteristics of these patients.Of the 240 pediatric cases identified, 131 (54.6%) were male. The median age at baseline was 6 years. The mean incidence rate was 81.4 cases per 100,000 person-years for the period from 2004 to 2011, and was highest among

2017 International Journal of Dermatology

35. Cutaneous Disseminated and Extracutaneous Sporotrichosis: Current Status of a Complex Disease Full Text available with Trip Pro

Cutaneous Disseminated and Extracutaneous Sporotrichosis: Current Status of a Complex Disease Sporotrichosis is an implantation or inoculation mycosis caused by species of Sporothrix schenckii complex; its main manifestations are limited to skin; however, cutaneous-disseminated, disseminated (visceral) and extracutaneous variants of sporotrichosis can be associated with immunosuppression, including HIV-AIDS, chronic alcoholism or more virulent strains. The most common extracutaneous form (...) of sporotrichosis includes pulmonary, osteoarticular and meningeal. The laboratory diagnosis requires observing yeast forms and isolating the fungus; the two main causative agents are Sporothrix schenckii (ss) and Sporothrix brasiliensis. Antibody levels and species recognition by Polimerase Chain Reaction using biological samples or cultures are also useful. The treatment of choice for most cases is amphotericin B and subsequent itraconazole for maintenance therapy.

2017 Journal of Fungi

36. Disseminated Sporotrichosis with Osteolytic Bone Involvement Full Text available with Trip Pro

Disseminated Sporotrichosis with Osteolytic Bone Involvement 28349410 2018 11 13 1525-1497 32 9 2017 Sep Journal of general internal medicine J Gen Intern Med Disseminated Sporotrichosis with Osteolytic Bone Involvement. 1063 10.1007/s11606-017-4048-4 Aronowitz Paul B PB Department of Internal Medicine, University of California, Davis, School of Medicine, 4150 V Street, Suite 3100, Sacramento, CA, 95817, USA. Paronowitz@ucdavis.edu. Gilroy Meghan M Division of Gastroenterology, Hepatology (...) & Nutrition, University of Utah, Salt Lake City, Utah, USA. Christiansen Katerina N KN Department of Internal Medicine, University of California, Davis, School of Medicine, 4150 V Street, Suite 3100, Sacramento, CA, 95817, USA. eng Journal Article 2017 03 27 United States J Gen Intern Med 8605834 0884-8734 clinical image dermatology diagnosis infectious disease sporotrichosis 2016 12 21 2017 03 09 2017 02 22 2017 3 30 6 0 2017 3 30 6 0 2017 3 29 6 0 ppublish 28349410 10.1007/s11606-017-4048-4 10.1007

2017 Journal of General Internal Medicine

37. Sporotrichosis by Sporothrix schenckii senso stricto with itraconazole resistance and terbinafine sensitivity observed in vitro and in vivo: Case report Full Text available with Trip Pro

Sporotrichosis by Sporothrix schenckii senso stricto with itraconazole resistance and terbinafine sensitivity observed in vitro and in vivo: Case report We report a case of a patient with lymphocutaneous sporotrichosis in the right upper limb. The fungus was identified as Sporothrix schenckii senso stricto by calmodulin gene sequencing. The initial treatment was itraconazole (200 mg/day), but in vitro antifungal susceptibility demonstrated high resistant to this and another six antifungals

2017 Medical mycology case reports

38. Painful linear ulcers: A case of cutaneous sporotrichosis mimicking pyoderma gangrenosum Full Text available with Trip Pro

Painful linear ulcers: A case of cutaneous sporotrichosis mimicking pyoderma gangrenosum 29264381 2019 02 26 2352-5126 3 6 2017 Nov JAAD case reports JAAD Case Rep Painful linear ulcers: A case of cutaneous sporotrichosis mimicking pyoderma gangrenosum. 519-521 10.1016/j.jdcr.2017.07.014 Charles Kristy K Department of Dermatology, Michigan Medicine, Ann Arbor, Michigan. Lowe Lori L Department of Dermatology, Michigan Medicine, Ann Arbor, Michigan. Department of Pathology, Michigan Medicine, Ann (...) Arbor, Michigan. Shuman Emily E Department of Infectious Disease, Michigan Medicine, Ann Arbor, Michigan. Cha Kelly B KB Department of Dermatology, Michigan Medicine, Ann Arbor, Michigan. eng Case Reports 2017 11 06 United States JAAD Case Rep 101665210 2352-5126 cutaneous sporotrichosis cutaneous ulcer sporotrichoid 2017 12 22 6 0 2017 12 22 6 0 2017 12 22 6 1 epublish 29264381 10.1016/j.jdcr.2017.07.014 S2352-5126(17)30163-7 PMC5729013 Curr Opin Infect Dis. 2008 Apr;21(2):129-33 18317034 Clin

2017 JAAD Case Reports

39. Cutaneous Nocardiosis Simulating Cutaneous Lymphatic Sporotrichosis Full Text available with Trip Pro

Cutaneous Nocardiosis Simulating Cutaneous Lymphatic Sporotrichosis Sporotrichosis is the subcutaneous mycosis caused by several species of the Sporothrix genus. With worldwide occurrence, the State of Rio de Janeiro is presently undergoing a zoonotic sporotrichosis epidemic. The form of lymphocutaneous nocardiosis is rare, being caused especially by Nocardia brasiliensis. It appears as a nodular or ulcerated lesion, with multiple painful erythematous nodules or satellite pustules distributed (...) along the lymphatic tract, similar to the lymphocutaneous variant of sporotrichosis. We present a 61-year-old man who, after an insect bite in the left leg, developed an ulcerated lesion associated with ascending lymphangitis, nonresponsive to previous antibiotic therapies. The patient was admitted for investigation, based on the main diagnostic hypothesis of lymphatic cutaneous sporotrichosis entailed by the highly suggestive morphology, associated with the epidemiologic information that he

2017 Case reports in dermatology

40. Rapidly Progressive Disseminated Sporotrichosis as the First Presentation of HIV Infection in a Patient with a Very Low CD4 Cell Count Full Text available with Trip Pro

Rapidly Progressive Disseminated Sporotrichosis as the First Presentation of HIV Infection in a Patient with a Very Low CD4 Cell Count Sporotrichosis is a human and animal disease caused by species of the Sporothrix schenckii complex. It is classically acquired through traumatic inoculation of fungal elements. Most frequently, sporotrichosis presents as a fixed cutaneous or as a lymphocutaneous form. A much smaller number of cases occur as cutaneous disseminated and disseminated forms (...) . These cases require immediate diagnosis and management to reduce morbidity and mortality. We present the case of a 34-year-old male patient in whom the first presentation of HIV infection was a rapidly progressive sporotrichosis with multiple cutaneous lesions, a high fungal burden in tissues, and pulmonary involvement. He had an extremely low CD4 cell count (06/mm3). Treatment with amphotericin B deoxycholate led to complete clinical resolution. Sporotrichosis remains a neglected opportunistic infection

2017 Case reports in infectious diseases

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