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Sporotrichosis

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301. Cutaneous sporotrichosis in Bangalore, southern India. (Abstract)

Cutaneous sporotrichosis in Bangalore, southern India. Sporotrichosis is a granulomatous infection caused by Sporothrix schenkii. Although world-wide in distribution, only four cases have been reported from southern India to date.The medical records of all cases seen at the Department of Dermatology at St John's Medical College Hospital, Bangalore, over the last 15 years were reviewed.A total of seven cases of sporotrichosis were seen in this 15-year period.Sporotrichosis is considered to occur

2004 International Journal of Dermatology

302. Epidemiology of sporotrichosis: a study of 304 cases in Brazil. (Abstract)

Epidemiology of sporotrichosis: a study of 304 cases in Brazil. Sporotrichosis is an infection caused by Sporothrix schenckii . It primarily involves the skin and lymphatic channels, but dissemination may occur.We sought to describe clinical and epidemiologic features of cases of sporotrichosis observed in southern Brazil, and to review the literature. Methods We conducted a retrospective analysis of medical records over a 35-year period, from 1967 to 2002.In all, 304 cases of sporotrichosis (...) confirmed by fungal culture, histopathologic examination, and/or remission of lesions with potassium iodide were reviewed. No statistical difference was found between the number of patients with fixed cutaneous sporotrichosis and those with the lymphangitic type. Multifocal and extracutaneous involvement was verified. The upper extremity was the most affected site. Unusual sites, such as the penis and pubic region, were also involved.Sporotrichosis is endemic in the study area. There is much

2005 Journal of American Academy of Dermatology

303. Disseminated sporotrichosis mimicking sarcoidosis. (Abstract)

Disseminated sporotrichosis mimicking sarcoidosis. A 40-year-old Caucasian man presented to the dermatology clinic at Baylor College of Medicine, Houston, Texas, in February 2003, for the evaluation of three nonhealing ulcers. The patient's past medical history was significant for hypothyroidism and pulmonary sarcoidosis, the diagnosis of which was made in June 2000. In March 2000, the patient had complained of cough and shortness of breath. A purified protein derivative (PPD) (Mantoux text (...) , periodic acid-Schiff (PAS) staining demonstrated small fungal spores (Fig. 4) morphologically consistent with sporotrichosis, within the cytoplasm of multinucleated histiocytic giant cells (Fig. 5). Additional stains for bacteria and acid-fast organisms were negative. Cultures of the biopsy specimens from all three sites grew Sporothrix schenckii. Further questioning of the patient failed to reveal an obvious source of the infection. The patient denied any history of traumatic skin inoculation and did

2006 International Journal of Dermatology

304. Efficacy of terbinafine and itraconazole on a experimental model of systemic sporotrichosis Full Text available with Trip Pro

Efficacy of terbinafine and itraconazole on a experimental model of systemic sporotrichosis Itraconazole is currently considered the drug of choice to treat the diverse clinical presentation of sporotrichosis. On the other hand terbinafine by virtue of its excellent in vitro activity is under comparative evaluation for its therapeutic potential for a wide range of fungal infections. In this study, our aim was to determine the in vivo efficacy of terbinafine and itraconazole on a experimental (...) model of systemic sporotrichosis. 120 rats Wistar received an injection of 2×10(3) S. schenckii cells by via the lateral tail vein. After 3 days the animals were treated with terbinafine (250mg/kg) and itraconazole (100 mg/kg) and their respective diluents. In our model, terbinafine and itraconazole were effective in reducing the number of clinical lesions and positive organ cultures. There was statistical difference between the groups treated with the antifungals in relation to the control groups

2008 Brazilian Journal of Microbiology

305. Use of Mycelial-Phase Sporothrix schenckii Exoantigens in an Enzyme-Linked Immunosorbent Assay for Diagnosis of Sporotrichosis by Antibody Detection Full Text available with Trip Pro

Use of Mycelial-Phase Sporothrix schenckii Exoantigens in an Enzyme-Linked Immunosorbent Assay for Diagnosis of Sporotrichosis by Antibody Detection An enzyme-linked immunosorbent assay (ELISA) was developed for specific antibody detection in serum specimens of patients with sporotrichosis. The assay was made with mycelial-phase Sporothrix schenckii exoantigens and was tested against 90 sera from patients with different clinical forms of sporotrichosis. Potential cross-reactions were analyzed (...) with 72 heterologous sera from patients with paracoccidioidomycosis, cryptococcosis, aspergillosis, histoplasmosis, tuberculosis, and American tegumentary leishmaniasis, as well as 76 sera from healthy controls. We found a sensitivity of 97% and a specificity of 89% in this assay. Some cross-reactions were seen, as observed in other immunoassays for the diagnosis of sporotrichosis. The ELISA appears to be especially useful for cutaneous forms of disease, since these are not promptly diagnosed

2007 Clinical and Vaccine Immunology

306. Sporotrichosis, Plain of Jars, Lao People's Democratic Republic Full Text available with Trip Pro

Sporotrichosis, Plain of Jars, Lao People's Democratic Republic 16673522 2006 05 18 2018 11 13 1080-6040 11 9 2005 Sep Emerging infectious diseases Emerging Infect. Dis. Sporotrichosis, Plain of Jars, Lao People's Democratic Republic. 1496-7 Newton Paul N PN Chung Wen-Hung WH Phetsouvanh Rattanaphone R White Nicholas J NJ eng Wellcome Trust United Kingdom Case Reports Letter Research Support, Non-U.S. Gov't United States Emerg Infect Dis 9508155 1080-6040 0 Antifungal Agents 304NUG5GF4 (...) Itraconazole IM Adult Antifungal Agents therapeutic use Female Humans Itraconazole therapeutic use Laos Sporotrichosis diagnosis drug therapy pathology 2006 5 6 9 0 2006 5 19 9 0 2006 5 6 9 0 ppublish 16673522 PMC3310628 10.3201/eid1109.050240 Trans R Soc Trop Med Hyg. 1999 Jan-Feb;93(1):41-5 10492787 Clin Infect Dis. 1999 Aug;29(2):231-6; quiz 237 10476718 Med J Aust. 1998 Sep 7;169(5):287 9762077 J Clin Microbiol. 1993 Feb;31(2):175-8 8381805 Clin Infect Dis. 2000 Jan;30(1):65-70 10619735 Clin Infect Dis

2005 Emerging Infectious Diseases

307. Successful treatment of nasal sporotrichosis in a dog Full Text available with Trip Pro

Successful treatment of nasal sporotrichosis in a dog Sporotrichosis is an uncommon mycosis of dogs caused by Sporothrix schenckii. This report details the diagnosis and treatment of intranasal sporotrichosis in a dog presented for a loss of smell, sneezing, and nasal congestion. Following 6 months of itraconazole treatment, a computed tomography scan showed a complete resolution of previously identified abnormalities.

2007 The Canadian Veterinary Journal

308. Comparative evaluation of the efficacy and safety of two doses of terbinafine (500 and 1000 mg day(-1)) in the treatment of cutaneous or lymphocutaneous sporotrichosis. (Abstract)

Comparative evaluation of the efficacy and safety of two doses of terbinafine (500 and 1000 mg day(-1)) in the treatment of cutaneous or lymphocutaneous sporotrichosis. The aim of this study was to evaluate the safety and efficacy of oral terbinafine (500 and 1000 mg day(-1)) in the treatment of cutaneous or lymphocutaneous sporotrichosis. A culture for Sporothrix schenckii was required for inclusion into this multicentre, randomized, double-blind, parallel-group study. Patients received either (...) was well tolerated and the frequency of drug-related AEs was slightly higher in the 1000 mg treatment group. Both doses of terbinafine were well-tolerated and effective for the treatment of sporotrichosis. The 1000 mg day(-1) terbinafine dose was more efficacious than 500 mg day(-1) in the treatment of cutaneous or lymphocutaneous sporotrichosis.

2004 Mycoses Controlled trial quality: uncertain

309. Phase II Study of Fluconazole for Lymphocutaneous and Visceral Sporotrichosis

Phase II Study of Fluconazole for Lymphocutaneous and Visceral Sporotrichosis Phase II Study of Fluconazole for Lymphocutaneous and Visceral Sporotrichosis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Phase II Study of Fluconazole for Lymphocutaneous and Visceral Sporotrichosis The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00004938 Recruitment Status : Completed First Posted : February 25, 2000 Last Update Posted : June 9, 2006 Sponsor: National Institute of Allergy and Infectious Diseases

2000 Clinical Trials

310. Phase I/II Study of Itraconazole for Blastomycosis, Histoplasmosis, and Sporotrichosis

Phase I/II Study of Itraconazole for Blastomycosis, Histoplasmosis, and Sporotrichosis Phase I/II Study of Itraconazole for Blastomycosis, Histoplasmosis, and Sporotrichosis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies (...) before adding more. Phase I/II Study of Itraconazole for Blastomycosis, Histoplasmosis, and Sporotrichosis The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00004811 Recruitment Status : Completed First Posted : February 25, 2000 Last Update Posted : June 9, 2006 Sponsor: National Center for Research

2000 Clinical Trials

311. Phase II Pilot Study of Fluconazole for Histoplasmosis, Blastomycosis, and Sporotrichosis

Phase II Pilot Study of Fluconazole for Histoplasmosis, Blastomycosis, and Sporotrichosis Phase II Pilot Study of Fluconazole for Histoplasmosis, Blastomycosis, and Sporotrichosis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) studies before adding more. Phase II Pilot Study of Fluconazole for Histoplasmosis, Blastomycosis, and Sporotrichosis The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00004808 Recruitment Status : Completed First Posted : February 25, 2000 Last Update Posted : June 9, 2006 Sponsor: National Center

2000 Clinical Trials

312. Laryngeal sporotrichosis causing stridor in a young child. (Abstract)

Laryngeal sporotrichosis causing stridor in a young child. Fungal infections of the larynx are rare entities that must be considered in the differential diagnosis of the patient who presents with laryngeal symptoms. We present an unusual case of initially recurrent and then persistent stridor in a 19-month-old girl, unresponsive to 4 months of antibiotic and steroid therapy. Upon our laryngoscopic examination, the patient was noted to have an ulcerated, granulomatous process involving (...) the larynx. She also had an erythematous papule on the left thigh. Fungal cultures of both sites grew Sporothrix schenckii. The patient was treated with systemic antifungal medications and had complete resolution of her symptoms. We discuss the pathophysiology and possible source of this unusual form of sporotrichosis, the first such case reported in a child. We emphasize the role of empiric steroid therapy in exacerbating and eventually enabling dissemination of the infection. We also review

2003 International Journal of Pediatric Otorhinolaryngology

313. Disseminated sporotrichosis associated with treatment with immunosuppressants and tumor necrosis factor-alpha antagonists. Full Text available with Trip Pro

Disseminated sporotrichosis associated with treatment with immunosuppressants and tumor necrosis factor-alpha antagonists. We report a case of disseminated sporotrichosis in a 49-year-old man who was treated with multiple immunosuppressants, including tumor necrosis factor (TNF)-alpha antagonists (etanercept and infliximab), for presumed inflammation arthritis. This case illustrates the potential for infectious complications related to the use of cytotoxic immunosuppressants and anticytokine

2003 Clinical Infectious Diseases

314. Population-based surveillance and a case-control study of risk factors for endemic lymphocutaneous sporotrichosis in Peru. Full Text available with Trip Pro

Population-based surveillance and a case-control study of risk factors for endemic lymphocutaneous sporotrichosis in Peru. Population-based surveillance and a case-control study were conducted in Abancay, Peru, to estimate the burden of disease and to determine risk factors for sporadic lymphocutaneous sporotrichosis (LS). Laboratory records from local hospitals were reviewed for the years of 1997 and 1998, and prospective surveillance was conducted for the period of September 1998 through

2003 Clinical Infectious Diseases

315. Potassium iodide remains the most effective therapy for cutaneous sporotrichosis. (Abstract)

Potassium iodide remains the most effective therapy for cutaneous sporotrichosis. Sporotrichosis is a subcutaneous fungal infection caused by the dimorphic fungus Sporothrix schenckii. Itraconazole has largely replaced older therapies, but we present a case of lymphocutaneous sporotrichosis that failed to respond to an adequate course of itraconazole yet responded dramatically to treatment with saturated solution of potassium iodide (SSKI).

2003 Journal of Dermatological Treatment

316. Sporotrichosis with widespread cutaneous lesions: report of 24 cases related to transmission by domestic cats in Rio de Janeiro, Brazil. (Abstract)

Sporotrichosis with widespread cutaneous lesions: report of 24 cases related to transmission by domestic cats in Rio de Janeiro, Brazil. Sporotrichosis most commonly presents as a localized lymphocutaneous infection following traumatic inoculation of soil, vegetables or organic substrates contaminated with the dimorphic fungus Sporothrix schenckii. Cases of widespread cutaneous lesions are rare. There have been isolated reports of household outbreaks of sporotrichosis involving cats (...) and humans.We report 24 cases of culture-proven sporotrichosis presenting with widespread cutaneous lesions.These 24 cases are part of an epidemic currently occurring in Rio de Janeiro. All patients reported contact with cats with sporotrichosis and 17 reported a history of a scratch or bite. Clinical manifestations included fixed lesions at multiple anatomical sites, and fixed lesions associated with the lymphocutaneous, bilateral lymphocutaneous and mucosal forms of the disease. Two patients were

2003 International Journal of Dermatology

317. Sporotrichosis. (Abstract)

Sporotrichosis. Sporotrichosis is a cutaneous fungal infection with a global distribution. The disease has several clinical forms, primarily cutaneous with associated lymphadenopathy. However, dissemination to osteoarticular structures and viscera may occur, both in healthy and immunosuppressed individuals; such disseminated forms usually follow spread after inhalation of fungal spores. Cutaneous infection is usually associated with trauma during the course of outdoor work, and treatment

2002 Clinical & Experimental Dermatology

318. Feline-transmitted sporotrichosis in the southwestern United States. Full Text available with Trip Pro

Feline-transmitted sporotrichosis in the southwestern United States. 1877193 1991 09 24 2018 11 13 0093-0415 154 4 1991 Apr The Western journal of medicine West. J. Med. Feline-transmitted sporotrichosis in the southwestern United States. 462-5 Caravalho J J Jr Department of Medicine, William Beaumont Army Medical Center, El Paso, Texas. Caldwell J B JB Radford B L BL Feldman A R AR eng Case Reports Journal Article United States West J Med 0410504 0093-0415 1C4QK22F9J Potassium Iodide (...) 7XU7A7DROE Amphotericin B AIM IM Adult Amphotericin B therapeutic use Animals Cats Clinical Protocols standards Diagnosis, Differential Disease Vectors Humans Male Potassium Iodide therapeutic use Sporotrichosis diagnosis drug therapy transmission Texas 1991 4 11 19 15 2001 3 28 10 1 1991 4 11 19 15 ppublish 1877193 PMC1002802 Rev Infect Dis. 1987 Jan-Feb;9 Suppl 1:S109-13 3027833 Arch Dermatol. 1986 Apr;122(4):413-7 3006602 J Am Acad Dermatol. 1989 May;20(5 Pt 2):964-7 2715452 Int J Dermatol. 1988 Jan

1991 Western Journal of Medicine

319. Comparison between histochemical and immunohistochemical methods for diagnosis of sporotrichosis. Full Text available with Trip Pro

Comparison between histochemical and immunohistochemical methods for diagnosis of sporotrichosis. To compare the efficacy of histochemical and immunohistochemical methods in detecting forms of Sporothrix schenckii in tissue.Thirty five cutaneous biopsy specimens from 27 patients with sporotrichosis were stained by histochemical haematoxylin and eosin, periodic acid Schiff, and Gomori's methenamine silver methods and an immunohistochemical (avidin-biotin complex immunoperoxidase) (ABC) technique (...) is concluded that immunostaining is an easy and rapid method which can efficiently increase the accuracy of the diagnosis of sporotrichosis in human tissue.

1992 Journal of Clinical Pathology

320. Sporotrichosis of the nose with spontaneous cure. Full Text available with Trip Pro

Sporotrichosis of the nose with spontaneous cure. 7260788 1981 10 29 2018 11 13 0008-4409 124 8 1981 Apr 15 Canadian Medical Association journal Can Med Assoc J Sporotrichosis of the nose with spontaneous cure. 1027 Bargman H B HB eng Case Reports Journal Article Canada Can Med Assoc J 0414110 0008-4409 AIM IM Adult Dermatomycoses Humans Male Nose Remission, Spontaneous Sporotrichosis 1981 4 15 1981 4 15 0 1 1981 4 15 0 0 ppublish 7260788 PMC1705375 Arch Intern Med. 1972 Dec;130(6):910-2

1981 Canadian Medical Association Journal

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