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Sporotrichosis

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281. Systemic Mycoses

with an abrupt, downward-sloping border often seen. Paracoccidioidomycosis . [ ] Also known as South American blastomycosis, it is only found in patients who have lived in South or Central Africa or Mexico and initially affects the upper respiratory tract. It usually appears with ulceration of the upper respiratory tract. Ulcers can coalesce to destroy the epiglottis, vocal cords and uvula. Eating and drinking are very painful. There may be skin lesions on the face. Sporotrichosis . [ ] This occurs when (...) dermatitidis: Antibody Detection in Sera from Dogs with Blastomycosis with Yeast Lysate Antigens Produced from Human and Dog Isolates. Vet Med Int. 20142014:376725. doi: 10.1155/2014/376725. Epub 2014 Feb 27. ; Serology of paracoccidioidomycosis due to Paracoccidioides lutzii. PLoS Negl Trop Dis. 2014 Jul 178(7):e2986. doi: 10.1371/journal.pntd.0002986. eCollection 2014 Jul. ; Sporotrichosis: an emerging neglected opportunistic infection in HIV-infected patients in Rio de Janeiro, Brazil. PLoS Negl Trop

2008 Mentor

282. Randomized Comparative Study of Fluconazole Versus Clotrimazole Troches in the Prevention of Serious Fungal Infection in Patients With AIDS or Advanced AIDS-Related Complex. (A Nested Study of ACTG 081)

). Antipneumocystis prophylaxis. Allowed: Topical suppressive antifungal agents. Eligibility requirements are: Participation in NIAID ACTG 081. No history of systemic fungal infection, including esophageal or systemic candidiasis, cryptococcosis, histoplasmosis, coccidioidomycosis, blastomycosis, sporotrichosis, or aspergillosis. Willingness to sign an informed consent. Transaminases < 5 x upper limit of normal. Noncompliance will not be a reason for withdrawal of a patient from the study, unless patient refuses (...) esophageal or systemic candidiasis, cryptococcosis, histoplasmosis, coccidioidomycosis, blastomycosis, sporotrichosis, or aspergillosis. Active systemic fungal infection at time of enrollment. Active superficial fungal infection at time of entry. (Such patients may be treated with topical antifungal agents and may be randomized if they are in clinical remission 14 days after completion of such therapy.) Concurrent Medication: Excluded: Amphotericin B. Fluconazole. Itraconazole. SCH 39304. Other systemic

1999 Clinical Trials

283. Sporotrichoid cutaneous Mycobacterium avium complex infection. (Abstract)

ulcers, inflammatory nodules, panniculitis, pustular lesions, and draining sinuses. Localized skin involvement resembling sporotrichosis is unusual and to our knowledge has been reported only once in the English-language literature. We describe an additional case of primary cutaneous M avium complex infection manifesting as sporotrichosis-like lesions on a patient with AIDS.

2002 Journal of American Academy of Dermatology

284. Retinal granuloma caused by Sporothrix schenckii. (Abstract)

Retinal granuloma caused by Sporothrix schenckii. To describe an unusual case of disseminated sporotrichosis with intraocular involvement.Interventional case report.An 18-year-old man presented with disseminated ulcerated skin lesions. Fundus examination showed fluffy opacities in the vitreous and a retinal granuloma in the left eye. Biopsy of the skin lesion and lymph node showed the presence of numerous fungus cells. Culture was positive for the diagnosis of disseminated (...) sporotrichosis.Although intraocular infection due to Sporothrix schenckii is uncommon, it can occur in case of disseminated sporotrichosis. Systemic therapy is a successful means to control skin and ocular sporotrichosis.

2003 American Journal of Ophthalmology

285. Fungal arthritis. Full Text available with Trip Pro

Cryptococcosis complications Histoplasmosis complications Humans Mycoses complications Sporotrichosis complications 106 1992 5 1 1992 5 1 0 1 1992 5 1 0 0 ppublish 1616344 PMC1005712 J Rheumatol. 1985 Aug;12(4):805-8 3877169 Ann Rheum Dis. 1985 Feb;44(2):128-9 3856420 Arthritis Rheum. 1985 Dec;28(12):1421-4 4084332 Ann Intern Med. 1985 Dec;103(6 ( Pt 1)):872-9 4062088 Arthritis Rheum. 1985 May;28(5):516-21 4004961 South Med J. 1990 Aug;83(8):957-60 2200140 Lancet. 1990 Jun 16;335(8703):1475 1972255 Clin

1992 Annals of the Rheumatic Diseases

287. Heterologous Expression, Purification, and Immunological Reactivity of a Recombinant HSP60 from Paracoccidioides brasiliensis Full Text available with Trip Pro

that the recombinant P. brasiliensis HSP60 was recognized by antibodies in 72 of 75 sera from paracoccidioidomycosis patients. No cross-reactivity was detected with individual sera from patients with aspergillosis, sporotrichosis, cryptococcosis, and tuberculosis. Reactivity to HSP60 was observed in sera from 9.52% of control healthy individuals and 11.5% of patients with histoplasmosis. The high sensitivity and specificity (97.3 and 92.5%, respectively) for HSP60 suggested that the recombinant protein can be used

2002 Clinical and Diagnostic Laboratory Immunology

288. Isolation, purification, and radiolabeling of a novel 120-kD surface protein on Blastomyces dermatitidis yeasts to detect antibody in infected patients. Full Text available with Trip Pro

, coccidioidomycosis, sporotrichosis, or candidiasis (titers, 1:86 and 1:91) and in none of 44 healthy persons. WI-1 was shown to be a surface molecule abundant on B. dermatitidis yeasts that were indirectly stained with serum from a rabbit immunized with WI-1. Approximately 0.93 pg of WI-1 or 4.7 x 10(6) WI-1 molecules were found on the surface of an individual yeast using an antigen-inhibition RIA; none was found on Histoplasma capsulatum or Candida albicans yeasts. We conclude that WI-1 is a novel

1990 Journal of Clinical Investigation

289. Itraconazole in the treatment of human mycoses: review of three years of clinical experience. (Abstract)

. A randomized comparison of 50-mg and 100-mg daily doses for the treatment of skin mycoses indicated that the optimal dosage is 100 mg. The results of short courses of treatment for superficial dermatophytoses suggest that such regimens may be effective, and the results of an ongoing double-blind comparison of itraconazole and griseofulvin suggest that itraconazole is superior in these infections. The outcome of treatment of systemic mycoses with itraconazole, especially sporotrichosis, chromomycosis

1987 Reviews of infectious diseases

290. Biosynthesis and Functions of Melanin in Sporothrix schenckii Full Text available with Trip Pro

Biosynthesis and Functions of Melanin in Sporothrix schenckii Sporothrix schenckii is a human pathogen that causes sporotrichosis, an important cutaneous mycosis with a worldwide distribution. It produces dark-brown conidia, which infect the host. We found that S. schenckii synthesizes melanin via the 1,8-dihydroxynaphthalene pentaketide pathway. Melanin biosynthesis in the wild type was inhibited by tricyclazole, and colonies of the fungus were reddish brown instead of black on tricyclazole

2000 Infection and immunity

291. Cases from the Osler Medical Service at Johns Hopkins University. Diagnosis: P. carinii pneumonia and primary pulmonary sporotrichosis. (Abstract)

Cases from the Osler Medical Service at Johns Hopkins University. Diagnosis: P. carinii pneumonia and primary pulmonary sporotrichosis. PRESENTING FEATURES: A 53-year-old man who had human immunodeficiency virus (HIV) presented to the Johns Hopkins Hospital with a 3-month history of increasing dysphagia, cough, dyspnea, chest pain, and an episode of syncope. His past medical history was notable for oral and presumptive esophageal candidiasis that was treated with fluconazole 6 months prior

2004 American Journal of Medicine

292. Sporotrichosis in Uttarakhand (India): a report of nine cases. (Abstract)

Sporotrichosis in Uttarakhand (India): a report of nine cases. Sporotrichosis is a chronic granulomatous infection caused by Sporothrichum schenckii. The disease has worldwide distribution. Majority of cases from India are reported from North-eastern states.The demographic, clinico-investigative profile and therapeutic results of nine patients with cutaneous sporotrichosis attending the Dermatology Outdoor Department between January 2005 and June 2006 have been compiled.Out of nine (male-4 (...) , female-5) patients, five had lymphocutaneous-type sporotrichosis while four had fixed cutaneous sporotrichosis. The average age of these patients was 40.8 years. The duration of complaints ranged from 1 month to 15 months (average 8.6 months). Two patients were able to recall traumatic injury. Six patients had lesions over lower extremities, two over face and one over upper extremity. Histopathologically, all cases showed granulomatous process with mixed inflammatory infiltrate comprising

2008 International Journal of Dermatology

293. Outbreak of sporotrichosis, Western Australia. Full Text available with Trip Pro

Outbreak of sporotrichosis, Western Australia. A cluster of sporotrichosis cases occurred in the Busselton-Margaret River region of Western Australia from 2000 to 2003. Epidemiologic investigation and mycologic culture for Sporothrix schenckii implicated hay initially distributed through a commercial hay supplier as the source of the out-break. Declining infection rates have occurred after various community measures were instigated.

2007 Emerging Infectious Diseases

294. Clinical practice guidelines for the management of sporotrichosis: 2007 update by the Infectious Diseases Society of America. Full Text available with Trip Pro

Clinical practice guidelines for the management of sporotrichosis: 2007 update by the Infectious Diseases Society of America. Guidelines for the management of patients with sporotrichosis were prepared by an Expert Panel of the Infectious Diseases Society of America and replace the guidelines published in 2000. The guidelines are intended for use by internists, pediatricians, family practitioners, and dermatologists. They include evidence-based recommendations for the management of patients (...) with lymphocutaneous, cutaneous, pulmonary, osteoarticular, meningeal, and disseminated sporotrichosis. Recommendations are also provided for the treatment of sporotrichosis in pregnant women and in children.

2007 Clinical Infectious Diseases

295. Endemic of Zoonotic Sporotrichosis: Profile of Cases in Children. (Abstract)

Endemic of Zoonotic Sporotrichosis: Profile of Cases in Children. Sporotrichosis in childhood is rare in most countries. Isolated cases and small outbreaks related to recreational activities or without identification of the transmission mechanism have been reported.Series of case reports. The isolation of Sporothrix schenckii from exudates or fragments of lesions obtained from the patients was used as the criterion of inclusion in the study.A total of 81 cases of sporotrichosis in children (...) , and 6 had spontaneous regression of the lesions.This is the largest series of childhood sporotrichosis with zoonotic transmission. The clinical presentation of sporotrichosis in children followed the same pattern of the disease in adults in this ongoing endemic.

2008 Pediatric Infectious Dsease Journal

296. Positive Montenegro skin test among patients with sporotrichosis in Rio De Janeiro. (Abstract)

Positive Montenegro skin test among patients with sporotrichosis in Rio De Janeiro. We studied 52 patients with sporotrichosis confirmed by isolation of Sporothrix schenckii and reactivity to the Montenegro skin test (MST) during an ongoing outbreak of this mycosis in Rio de Janeiro. The objective was to emphasize the importance of parasitological confirmation and the possibility of incorrect diagnosis based on the lesion's appearance, epidemiological information, and immunological tests (...) (84.6%) were treated with itraconazole. In the differential diagnosis between sporotrichosis and cutaneous leishmaniasis, the possibility of co-infection, allergy to the reagent diluent, and cross-reactions should be further investigated, especially in regions with limited laboratory facilities.

2005 Acta Tropica

297. A case of atypical sporotrichosis with multifocal cutaneous ulcers. (Abstract)

A case of atypical sporotrichosis with multifocal cutaneous ulcers. We report an atypical case of sporotrichosis in an elderly woman working as a horticulturist, who presented with multiple ulcers and nodules on the face and the right upper back. Histological examination found numerous small yeast-like spores in the granulomatous reaction in the upper dermis. Culture and DNA analysis identified Sporothrix schenckii, group B. Misuse of topical steroids and self-inoculation may have caused

2007 Clinical & Experimental Dermatology

298. Cat-transmitted sporotrichosis, Rio de Janeiro, Brazil. Full Text available with Trip Pro

Cat-transmitted sporotrichosis, Rio de Janeiro, Brazil. Sporotrichosis is an emerging zoonosis in Rio de Janeiro, Brazil. From 1998 to 2003, 497 humans and 1,056 cats with culture-proven sporotrichosis were studied. A total of 421 patients, 67.4% with a history of a scratch or bite, reported contact with cats that had sporotrichosis.

2005 Emerging Infectious Diseases

299. Cat-transmitted sporotrichosis epidemic in Rio de Janeiro, Brazil: description of a series of cases. Full Text available with Trip Pro

Cat-transmitted sporotrichosis epidemic in Rio de Janeiro, Brazil: description of a series of cases. Sporotrichosis is the most common subcutaneous mycosis in South America. Classic infection is associated with traumatic inoculation of soil, vegetables, and organic matter contaminated with Sporothrix schenckii. Zoonotic transmission has been described in isolated cases or in small outbreaks. Since 1998, we have been observing an increasing number of cases of sporotrichosis in persons from (...) the city of Rio de Janeiro, Brazil, and surroundings. From 1998 to 2001, 178 cases of culture-proven sporotrichosis had been diagnosed. Female patients predominated, and the median age was 39 years. The most frequent clinical presentation was lymphocutaneous disease. Of the 178 patients, 156 reported domiciliary or professional contact with cats with sporotrichosis, and 97 of these patients had a history of receipt of cat scratch or bite. The patients received itraconazole as first-line treatment

2004 Clinical Infectious Diseases

300. Importance of the direct fresh examination in the diagnosis of cutaneous sporotrichosis. (Abstract)

Importance of the direct fresh examination in the diagnosis of cutaneous sporotrichosis. To date the direct fresh examination has not been considered, except by a few authors, as a valid laboratory procedure for the diagnosis of cutaneous sporotrichosis.Forty-two patients with cutaneous sporotrichosis (36 lymphangitic and six fixed) were studied. Pus was obtained through digital compression of opened lesions followed by collection with a spatula and examination of the material between the slide

2004 International Journal of Dermatology

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