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Spondyloarthropathy

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161. Study to Evaluate the Effects of Fasinumab on Peripheral Nerve Function in Patients With Pain Due to Osteoarthritis of the Hip or Knee

/acetaminophen, or combinations thereof Consent to allow all radiographs and medical/surgical/hospitalization records of care received elsewhere prior to and during the study period to be shared with the investigator Key Exclusion Criteria: History or presence at the screening visit of non-OA inflammatory joint disease (eg, rheumatoid arthritis, lupus erythematosus, psoriatic arthritis, pseudo-gout, gout, spondyloarthropathy, polymyalgia rheumatica, joint infections within the past 5 years), Paget's disease

2018 Clinical Trials

162. Viable Allograft Supplemented Disc Regeneration in the Treatment of Patients With Low Back Pain

No chronic use (>7 consecutive days) of anticoagulants (such as aspirin) or NSAIDs prior to treatment Exclusion Criteria: Seropositive or seronegative spondyloarthropathy Type III Modic changes Prior surgeries of segments between L1 and S1 Chemonucleolysis or percutaneous laserectomy of the affected disc prior to the study Chronic facet syndrome Stenosis of the spinal canal that is moderate to severe or more in degree Spondylodiscitis Spondylolisthesis (lysis and degenerative) Severe motor deficit

2018 Clinical Trials

163. Trial of Ginsenoside Compound K (GCK) Tablet in Patients With Rheumatoid Arthritis

and comply with the requirements of the study protocol. Exclusion Criteria: Patients have prior exposure to any csDMARDs or bDMARDs. Patients have received corticosteroids, or Chinese medicine preparations such as tripterygium wilfordii, total glucosides of paeony for RA treatment. Patients with fibromyalgia Patients diagnosed with any systemic inflammatory disease other than RA, including but not limited to juvenile chronic arthritis, spondyloarthropathy, Crohn's disease, ulcerative colitis, psoriatic

2018 Clinical Trials

164. The Management of Acute Anterior Uveitis Complicating Spondyloarthritis: Present and Future (PubMed)

The Management of Acute Anterior Uveitis Complicating Spondyloarthritis: Present and Future Spondyloarthropathies (SpA) encompass a group of chronic inflammatory diseases sharing common genetic and clinical features, including the association with HLA-B27 antigen, the involvement of both the axial and the peripheral skeleton, the presence of dactylitis, enthesitis, and typical extra-articular manifestations such as psoriasis, inflammatory bowel disease, and acute anterior uveitis (AAU

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2018 BioMed research international

165. Current evidence for spinal X-ray use in the chiropractic profession: a narrative review (PubMed)

, with consideration of the related risks and benefits. Current evidence supports the use of spinal X-rays only in the diagnosis of trauma and spondyloarthropathy, and in the assessment of progressive spinal structural deformities such as adolescent idiopathic scoliosis. MRI is indicated to diagnose serious pathology such as cancer or infection, and to assess the need for surgical management in radiculopathy and spinal stenosis. Strong evidence demonstrates risks of imaging such as excessive radiation exposure

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2018 Chiropractic & manual therapies

166. An unexpected cause of sacroiliitis in a patient with gout and chronic psoriasis with inflammatory arthritis: a case report. (PubMed)

An unexpected cause of sacroiliitis in a patient with gout and chronic psoriasis with inflammatory arthritis: a case report. Inflammatory back pain is a condition characterized by inflammation of the sacroiliac joints and lower spine. It is frequently seen in patients with spondyloarthropathies like ankylosing spondylitis, psoriatic arthritis, enteropathic arthritis and reactive arthritis. Inflammatory back pain can be caused by many other conditions like infection and crystal deposition (...) such as gout. In this case, it is difficult to specifically identify gout as a cause by ordinary imaging like magnetic resonance imaging (MRI) or ultrasound.This case report describes a young man with severe psoriasis, presumptive psoriatic spondyloarthropathy and chronic extensive tophaceous gout which was difficult to treat because of non-compliance with medications and lifestyle. He presented with inflammatory type low back and buttocks pain with raised inflammatory markers. MRI of the lower back

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2018 BMC Musculoskeletal Disorders

167. Efficacy and Safety of a Intra-articular Injection, ENKO1, in Patients With Symptomatic Knee Osteoarthritis.

randomisation. Paget's disease of bone, chondromatosis or villonodular sinovitis. Inflammatory, infectious or metabolic arthritis (rheumatoid arthritis, spondyloarthropathy or connective tissue diseases). Haemochromatosis, ochronosis or haemophilia. History of diseases that the investigator considers likely to interfere with the functional disability assessment. Knee surgery planned during the study period. Other disease-related criteria: BMI greater than or equal to 30. Immunodeficiency or a serious

2018 Clinical Trials

168. Upright Back Posture Device Study

disc, lumbar spondylolysis, radiculitis, facet arthrosis, fibromyalgia, rheumatoid arthritis, seronegative spondyloarthropathy. Neurologic deficits on exam Currently in physical therapy (PT) Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03769246

2018 Clinical Trials

169. Effects of Aerobic Training in Patients with Ankylosing Spondylitis (PubMed)

were the Bath indexes [Bath AS Functional Index (BASFI), Bath AS Disease Activity Index (BASDAI), and Bath AS Metrology Index (BASMI)], Health Assessment Questionnaire for the Spondyloarthropathies (HAQ-S), AS Disease Activity Score (ASDAS), the 6-min walk test (6MWT), chest expansion, and the Medical Outcomes Study Short Form-36. Aerobic capacity was assessed by ergospirometry on a treadmill. Routine laboratory techniques were used in determining lipid levels. Assessments were performed

2016 EvidenceUpdates Controlled trial quality: uncertain

170. Cross-sectional survey of the undergraduate rheumatology curriculum in European medical schools: a EULAR School of Rheumatology initiative (PubMed)

. Similarly, interpretation of investigations undertaken on synovial fluid was taught in only 16 schools. While disease-modifying anti-rheumatic drugs and biological agents, and urate-lowering treatment were included in the curricula of 20 and 21 institutions, respectively, only curricula from 18 schools included core non-pharmacological interventions. Osteoarthritis, gout, rheumatoid arthritis, spondyloarthropathy, polymyalgia rheumatica and lupus were included in the curriculum of all institutions

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2018 RMD open

171. Can power Doppler ultrasound of the entheses help in classifying recent axial spondyloarthritis? Data from the DESIR cohort (PubMed)

% European Spondyloarthropathy Study Group criteria and 59% both.In a cohort of patients with recent IBP, the prevalence of PDUS enthesitis was low (14.4%); however, its specificity for classifying patients as axSpA according to ASAS criteria was high (83.5%). PDUS enthesitis might be of additional value for classifying as patients with axSpA IBP who do not fulfil ASAS criteria.

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2018 RMD open

172. Feasibility of cardiovascular disease risk assessments in rheumatology outpatient clinics: experiences from the nationwide NOCAR project (PubMed)

referred to their primary care physician for initiation of CVD preventive measures.Data collection (autumn 2015) showed that five of the NOCAR centres had implemented CVD risk assessments. There were 8789 patients eligible for CVD risk evaluation (rheumatoid arthritis (RA), 4483; ankylosing spondylitis (AS), 1663; psoriatic arthritis (PsA), 1928; unspecified and other forms of spondyloarthropathies (SpA), 715) of whom 41.4 % received a CVD risk assessment (RA, 44.7%; AS, 43.4%; PsA, 36.3%; SpA, 30.6

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2018 RMD open

173. A systematic evaluation of the therapeutic effectiveness of sacroiliac joint interventions

to be at least one month. Eligible patients were adults (at least 18 years old) with chronic low back and/or lower extremity pain which had lasted for at least three months and for whom other therapies had not worked. The primary outcome of interest was pain relief. Secondary outcomes were functional improvement, change in psychological status, return to work, reduction or elimination of opioid use/other interventions, and complications. Studies of spondyloarthropathy were excluded. Further inclusion

2012 DARE.

174. Dietary Supplement for Joint: the OLE Study

synovitis of the knee, seronegative spondyloarthropathy, rheumatoid arthritis, gouty arthritis , infectious arthritis, radiculalgia in the lower limbs, arteritis Prosthesis in the target knee Diagnosed arthrosis eligible to knee/joint surgery/replacement Related to treatments Analgesics to manage knee pain 24h before inclusion visit Corticosteroids injection in the target knee in the month preceding inclusion Hyaluronan injection in the target knee in the last 6 months Oral corticotherapy ≥ 5mg/day

2017 Clinical Trials

175. The SpACE Study

The SpACE Study The SpACE Study - Small Bowel Crohn's Disease and Spondyloarthropathies - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. The SpACE Study - Small Bowel Crohn's Disease (...) and Spondyloarthropathies (SpACE) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03064815 Recruitment Status : Completed First Posted : February 27, 2017 Last Update Posted : March 1, 2017 Sponsor: McGill University Health Center Collaborators: AbbVie Prometheus Laboratories Information provided by (Responsible Party

2017 Clinical Trials

176. Cartography and Quantitative Characterization of Achilles Tendon Fibrocartilage by TE = 0ms Imaging at 3T MRI

enthesis study using the calcaneal tendon as a clinical model Condition or disease Intervention/treatment Phase Spondyloarthropathy Tendinopathy Device: MRI ZTE2 sequence Not Applicable Detailed Description: The human body contains a lot of tissue components with short T2 (transversal relaxation time) that are not or only poorly detected on conventional T2-weighted MR sequences. These components are mostly located in musculoskeletal organs such as tendons, ligaments, menisci, periosteum or cortical (...) bone. Considering that conventional sequences do not detect tissue components with T2 shorter than 10ms, imaging of body tendon or enthesis is therefore very limited. This represents a limitation of MR imaging in early diagnosis of a certain number of pathologies, such as mechanical or mostly inflammatory tendinopathy or enthesopathy. This study, would provide the feasibility of ZTE 2 sequence to quantitatively assess normal and pathological spondyloarthropathy Achilles tendon enthesis at 3 T

2017 Clinical Trials

177. Cross-phenotype association mapping of the MHC identifies genetic variants that differentiate psoriatic arthritis from psoriasis. (PubMed)

PsC. This amino acid also represents the largest genetic effect for ankylosing spondylitis, thereby refining the genetic overlap of these two spondyloarthropathies. Correcting for bias has important implications for cross-phenotype genetic studies.© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

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2017 Annals of the Rheumatic Diseases

178. Hip resurfacing arthroplasty for patients with inflammatory arthritis: a systematic review. (PubMed)

in these series, however, their outcomes following resurfacing are underreported. The aim of this study was to determine complications that may occur following hip resurfacing in patients with inflammatory arthritis. A secondary aim was to determine functional outcomes following resurfacing.A search was performed in MEDLINE (PubMed/OVID), Cochrane Library, and Google Scholar. 5 studies met eligibility criteria. This review includes 196 hips; 120 had a diagnosis of AS or seronegative spondyloarthropathy and 76

2017 Hip international : the journal of clinical and experimental research on hip pathology and therapy

179. Serologic Evidence of Gut-driven Systemic Inflammation in Juvenile Idiopathic Arthritis. (PubMed)

Serologic Evidence of Gut-driven Systemic Inflammation in Juvenile Idiopathic Arthritis. Accumulating evidence links juvenile idiopathic arthritis (JIA) to nonhost factors such as gut microbes. We hypothesize that children with new-onset JIA have increased intestinal bacterial translocation and circulating lipopolysaccharide (LPS).We studied systemic treatment-naive patients with JIA [polyarticular JIA, n = 22, oligoarticular JIA, n = 31, and spondyloarthropathies (SpA), n = 16], patients

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2017 Journal of Rheumatology

180. Switching tumor necrosis factor inhibitors in the treatment of axial spondyloarthritis. (PubMed)

Switching tumor necrosis factor inhibitors in the treatment of axial spondyloarthritis. To assess the impact of switching tumor necrosis factor (TNF)-alpha inhibitors on patients with axial spondyloarthritis (axSpA).PubMed literature searches were conducted using combinations of search terms including ankylosing spondylitis, spondyloarthropathy, spondyloarthritis, switch/switching, drug survival, and TNF/tumor necrosis factor to identify published articles with data on outcomes related

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2017 Seminars in arthritis and rheumatism

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