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Spondyloarthropathy

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281. Kinesio Taping Efficacy in Chronic Low Back Pain Treatment (KITALO)

structures, spondyloarthropathy, spondylodiscitis). Prior spine surgery. Mental retardation, severe mental illness, substance abuse or dependency, illiteracy. Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02604290 Locations Layout table for location

2015 Clinical Trials

282. Strategy to Prevent the Onset of Clinically-Apparent Rheumatoid Arthritis

; A medical history of inflammatory arthritis (IA) of any type and/or rheumatic disease and immunologic disease(s) that may be associated with IA . These diseases include but are not limited to: rheumatoid arthritis (RA); systemic lupus erythematosus (SLE); seronegative spondyloarthropathies; inflammatory bowel disease; Sjögren's syndrome; polymyalgia rheumatic; or vasculitis. Note: Crystalline arthropathies are not exclusionary. A medical history of: congestive heart failure or functional status of New

2015 Clinical Trials

283. Fibrocytes in Early and Longstanding Rheumatoid Arthritis

disease (MCTD), scleroderma, polymyositis or primary vasculitis. History of or current inflammatory joint disease other than RA (e.g. gout, reactive arthritis, psoriatic arthritis, spondyloarthropathy, Lyme disease). Allergy to local aesthetics. Hereditary or acquired (e.g. Anticoagulant Treatment, apart from low dose aspirin) coagulation abnormality. Prednisolone above 7.5 mg/day Skin pathology at site of joint biopsy. Obesity, BMI > 30. Functional class IV as defined by the criteria

2015 Clinical Trials

284. Effect of Subcutaneous ACTEMRA on Inflamed Atherosclerotic Plaques in Patients With Rheumatoid Arthritis

of, or current inflammatory joint disease other than RA (e.g., gout, Lyme disease, seronegative spondyloarthropathy including reactive arthritis, psoriatic arthritis, arthropathy of inflammatory bowel disease). Relatively significant radiation exposure over the course of the year prior to randomization. Significant exposure is defined as: i) More than 2 PCI within 12 months of randomization ii) More than 2 myocardial perfusion studies within the past 12 months iii) More than 2 CT angiograms within the past

2015 Clinical Trials

285. Criterion-concurrent validity of spinal mobility tests in ankylosing spondylitis: a systematic review of the literature. (PubMed)

, spondyloarthropathy, spondylarthritis; mobility, spinal measure*, (a further 16 keywords with similar meaning were used). Seven databases were searched from their inception to February 2014: AMED, Embase, ProQuest, PubMed, Science Direct, Scopus, and Web of Science. The Quality Assessment of Diagnostic Accuracy Studies (with modifications) was used to assess the quality of articles reviewed. An article was considered high quality when it received "yes" in at least 9 of the 13 items.From the 741 records initially

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2015 Journal of Rheumatology

286. Assessment of Tender & Swollen Joints Count Score Performed by a Rheumatologist And Rheumatology Nurses in Patients With RA and PsA.

of more than 6 months. Subject must have a diagnosis of active PsA by Classification Criteria for Psoriatic Arthritis (CASPAR) and has disease duration of more than 6 months. The subject must be able to provide written informed consent and to complete the study questionnaires. Exclusion Criteria: Subject with DIP involvement in PsA Subject with predominant axial symptoms (spondyloarthropathy) Subject with fibromyalgia Subject involved in a concomitant study Subject currently takes ≥10 mg cortisone

2015 Clinical Trials

287. ASAS40 and ASDAS clinical responses in the ABILITY-1 clinical trial translate to meaningful improvements in physical function, health-related quality of life and work productivity in patients with non-radiographic axial spondyloarthritis. (PubMed)

-radiographic axial SpA (nr-axSpA).Data are from ABILITY-1, a phase 3 trial of adalimumab vs placebo in nr-axSpA patients. PROs included the HAQ for Spondyloarthropathies (HAQ-S), 36-item Short Form Health Survey (SF-36) physical component summary (PCS) score and Work Productivity and Activity Impairment Questionnaire. Patients were grouped by clinical response using ASAS40 response and ASDAS disease states at week 12. Changes in PROs from baseline to week 12 were compared between groups using analysis

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2015 Rheumatology (Oxford, England)

288. The intestinal microbiome in human disease and how it relates to arthritis and spondyloarthritis. (PubMed)

The intestinal microbiome in human disease and how it relates to arthritis and spondyloarthritis. Humans and microbes have developed a symbiotic relationship over time, and alterations in this symbiotic relationship have been linked to several immune mediated diseases such as inflammatory bowel disease, type 1 diabetes and spondyloarthropathies. Improvements in sequencing technologies, coupled with a renaissance in 16S rRNA gene based community profiling, have enabled the characterization (...) in the pathogenesis of spondyloarthropathies, and how this may relate to potential therapies for these conditions. Copyright © 2015 Elsevier Ltd. All rights reserved.

2015 Best practice & research. Clinical rheumatology

289. Construct validity of clinical spinal mobility tests in ankylosing spondylitis: a systematic review and meta-analysis. (PubMed)

) ankylosing spondylitis, spondyloarthritis, spondyloarthropathy, spondylarthritis; (ii) accuracy, association, construct, correlation, Outcome Measures in Rheumatoid Arthritis Clinical Trials, OMERACT, truth, validity; (iii) mobility, Bath Ankylosing Spondylitis Metrology Index-BASMI, radiography, spinal measures, cervical rotation, Schober (a further 19 keywords were used). Initially, 2558 records were identified, and from these, 21 studies were retained. Fourteen of these studies were considered high

2015 Clinical rheumatology

290. Topical Glyceryl Trinitrate (GTN) and Eccentric Exercises in the Treatment of Midportion Achilles Tendinopathy

: Previous corticosteroid injection to the affected tendon in the past 3 months Symptoms of less than 3 months duration Previous use of topical GTN Current use of nitrates, eg: GTN spray, tablet, transdermal patch. Contra-indication to GTN therapy (see section 12.2.3) Current pregnancy, breastfeeding or planning pregnancy VISA-A score > 80 Previous surgery to the affected Achilles tendon Seronegative spondyloarthropathy with Achilles enthesitis Previous performance of a heavy load eccentric exercise

2015 Clinical Trials

291. Musculoskeletal Ultrasound in Asymptomatic Hyperuricemia

two years without a clinical diagnosis of gout per American College of Rheumatology criteria30 (appendix A). Patients, of matched gender and age, with normal uric acid levels will serve as controls. Exclusion Criteria: Patients who meet or have met the ACR criteria for Gout, unable to read English, and/or have terminal illness will not be eligible to participate in the study. Patients with a diagnosis of skin psoriasis31, rheumatoid arthritis, or spondyloarthropathies will not be eligible

2015 Clinical Trials

292. A Study of MEDI7352 in Painful Osteoarthritis of the Knee

Exclusion Criteria: Current treatment with another biologic therapeutic agent Current of historical diagnosis of RA Current diagnosis of an immunological condition that is associated with another form of arthritis in addition to OA, including traumatic arthritis or a seronegative spondyloarthropathy At risk of destructive arthropathy, including Rapidly Progressive Osteoarthritis (RPOA), osteonecrosis, spontaneous osteonecrosis of the knee, subchondral insufficiency fractures, hip dislocation

2015 Clinical Trials

293. Ocular Involvement in Systemic Autoimmune Diseases. (PubMed)

Ocular Involvement in Systemic Autoimmune Diseases. Eye involvement represents a common finding in patients with systemic autoimmune diseases, particularly rheumatoid arthritis, Sjogren syndrome, seronegative spondyloarthropathy, and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. The eye is a privileged immune site but commensal bacteria are found on the ocular surface. The eye injury may be inflammatory, vascular or infectious, as well as iatrogenic, as in the case

2015 Clinical Reviews in Allergy & Immunology

294. Patient-physician discordance in global assessment in early spondyloarthritis and its change over time: the DESIR cohort. (PubMed)

Patient-physician discordance in global assessment in early spondyloarthritis and its change over time: the DESIR cohort. To assess patient-physician discordance in global assessment of disease activity in early axial spondyloarthritis (axSpA) over time and determinants of discordance.DESIR (Devenir des Spondyloarthropathies Indifférenciées Récentes) is a French, multicentre, longitudinal cohort of patients with early inflammatory back pain suggestive of axSpA. Patient global assessment (PGA

2015 Annals of the Rheumatic Diseases

295. Genetics of ankylosing spondylitis-insights into pathogenesis. (PubMed)

Genetics of ankylosing spondylitis-insights into pathogenesis. Ankylosing spondylitis (AS), an immune-mediated arthritis, is the prototypic member of a group of conditions known as spondyloarthropathies that also includes reactive arthritis, psoriatic arthritis and enteropathic arthritis. Patients with these conditions share a clinical predisposition for spinal and pelvic joint dysfunction, as well as genetic associations, notably with HLA-B(*)27. Spondyloarthropathies are characterized

2015 Nature reviews. Rheumatology

296. Extract of Curcuma Longa Complexed With Phosphatidilcholine(Motore®)in the Treatment of Adults With Knee Osteoarthritis

sterile (bilateral oophorectomy or hysterectomy); concomitant arthropathy that may confuse or interfere with pain assessment or efficacy, including: inflammatory arthropathy (rheumatoid arthritis, systemic lupus erythematosus, spondyloarthropathy, psoriatic arthritis, polymyalgia rheumatic), gouty arthritis, acute episodes of monoarthritis compatible with pseudogout, Paget's disease with involvement of the joint study, history of septic arthritis, avascular necrosis or intra-articular joint studied

2015 Clinical Trials

297. Safety and Efficacy Study of Rexlemestrocel-L in Subjects With Chronic Discogenic Lumbar Back Pain

Symptomatic central vertebral canal stenosis as defined by neurogenic claudication Spondylolisthesis or retrolisthesis Grade 2 and above or Spondylolysis at the index or adjacent level(s) Lumbar spondylitis or other undifferentiated spondyloarthropathy affecting the index disc Spinal deformity defined as lumbar scoliosis with a Cobb angle of the lumbar spine greater than 15 degrees Any fracture of the spine at the index or adjacent levels that has not healed, or clinically compromised vertebral bodies

2015 Clinical Trials

298. Analysis of HLA-B15 and HLA-B27 in spondyloarthritis with peripheral and axial clinical patterns. (PubMed)

to European Spondyloarthropathy Study Group (ESSG) criteria. Patients were then classified according to ASAS criteria, the axial spondyloarthritis pattern (axSpA) being defined by ascertained sacroiliitis and the peripheral pattern (pSpA) by enthesitis and/or arthritis in extremities. A combined ax/p pattern was also considered.Only HLA-B27 and HLA-B15 alleles were associated with SpA. ASAS criteria for axSpA were met in 152 patients (12 with isolated axSpA and 140 with a combined ax/p patterns). When

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2015 BMJ open

299. 'MHC-I-opathy'-unified concept for spondyloarthritis and Behçet disease. (PubMed)

'MHC-I-opathy'-unified concept for spondyloarthritis and Behçet disease. The spondyloarthropathies comprise ankylosing spondylitis (AS), reactive arthritis, psoriatic arthritis (PsA) and arthritis associated with inflammatory bowel disease. In this Perspectives article, we describe how Behçet disease and several clinically distinct spondyloarthropathies-all associated with MHC class I (MHC-I) alleles such as HLA-B(*)51, HLA-C(*)0602 and HLA-B(*)27 and epistatic ERAP-1 interactions-have a shared

2015 Nature reviews. Rheumatology

300. Heterogeneity of Synovial Molecular Patterns in Patients with Arthritis (PubMed)

biopsies of patients with arthritis, using low-density platforms.Low-density assays (cDNA microarray and microfluidics qPCR) were designed, based on the results of the high-density microarray data. Knee synovial biopsies were obtained from patients with RA, spondyloarthropathies (SA) or osteoarthritis (OA) (n = 39), and also from patients with initial undifferentiated arthritis (UA) (n = 49).According to high-density microarray data, several molecular pathways are differentially expressed in patients

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2015 PloS one

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