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261. Development of the General Scale Observance for Chronic Diseases

Criteria: patient age of 18 years from routine patient counseling with at least one of these diseases : heart failure, hypertension, coronary disease, type 2 diabetes, osteoarthritis of the knee or hip, osteoporosis, inflammatory rheumatism (rheumatoid arthritis, spondyloarthropathy), cancer ( with only non-hormonal oral anti cancer treatments) and HIV. patient can read the French language in order to complete the self -administered questionnaire patient agreeing to participate in the study Exclusion

2016 Clinical Trials

262. C.O.R.P.U.S.: Observational Cohort of Adult and Child Inflammatory Arthritis in France

table for eligibility information Ages Eligible for Study: 3 Years to 75 Years (Child, Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Sampling Method: Non-Probability Sample Study Population Patients suffering rheumatoid arthritis, spondyloarthropathy or idiopathic juvenile arthritis, recruited with rheumatologist in public and private practice Criteria Inclusion Criteria: Diagnosis by rheumatologist of rheumatoid arthritis DAS score > 3.2, any age of onset hand

2016 Clinical Trials

263. A Pilot Study of MSCs Iufusion and Etanercept to Treat Ankylosing Spondylitis

anti-TNF therapy within 3 months pregnant or suckling period female patients; Patients with the Medical or mentally imbalance charged by researchers. patients associated cardiovascular, cerebrovascular, liver,renal and hematological system diseases or mental disease; Patients could not accept the research or could not cooperate well. Patients with other sever diseases at the same time, such as abnormality of joints, other seronegative spondyloarthropathy, or other Rheumatic Diseases. Contacts

2016 Clinical Trials

264. FDG PET/MRI Evaluation of Facet Joint Pain

spondyloarthropathies and myopathies, but is also lacking. This is an exploratory study investigating the utility of FDG PET activity and MRI signal change around facet joints in the clinical management of low back pain. This study will help determine if such imaging biomarkers could change clinical management. Additionally, this will provide data that will be vital to planning a larger prospective study evaluating the ability of imaging biomarkers to predict response to comparison medial branch blocks and RF

2016 Clinical Trials

265. Evaluation of the Evolution of Imaging Markers of Cartilage Degradation in Patients With Knee Osteoarthritis Receiving DROGLICAN

interfering with the evaluation of OA and/or pain such as articular dysplasia, aseptic osteonecrosis, acromegaly, Paget's disease, hemophilia, hemochromatosis, chondromatosis, villonodular synovitis of the knee, seronegative spondyloarthropathy, rheumatoid arthritis, gouty arthritis , infectious arthritis, radiculalgia in the lower limbs, arteritis, etc. Radiological K&L grade I or IV Prosthesis in the target knee Related to treatments Analgesics to manage OA knee pain 24h before inclusion visit

2016 Clinical Trials

266. Clinical Performance of B-Lite® Light Weight Breast Implant

, if medically required The patient has a confirmed rheumatic disease or syndrome (e.g., SLE, Sjogren's syndrome, scleroderma, polymyositis or any connective tissue disorder, rheumatoid arthritis, crystalline arthritis, infectious arthritis, spondyloarthropathies, any other inflammatory arthritis, fibromyalgia or chronic fatigue syndrome) The patient has a severe breast and upper trunk deformity The patient participated in an investigational trial within 90 days of enrollment The patient has undergone

2016 Clinical Trials

267. PK, PD, Safety, and Efficacy of SAIT101 Versus MabThera® Versus Rituxan® in Patients With Rheumatoid Arthritis

/bed bound. History of or current inflammatory joint disease other than RA (including but not limited to gout, reactive arthritis, psoriatic arthritis, seronegative spondyloarthropathy or Lyme disease). History of or current systemic autoimmune disorder (including but not limited to systemic lupus erythematosus, inflammatory bowel disease, pulmonary fibrosis, Felty syndrome, scleroderma, inflammatory myopathy, fibromyalgia, juvenile idiopathic arthritis, mixed connective tissue disease, vasculitis

2016 Clinical Trials

268. Ultrasound Features of the Posterior Tibialis Tendon and Peroneus Brevis Tendon Entheses: A Comparison Study between Healthy Adults and Inflammatory Arthritis. Full Text available with Trip Pro

subjects were enrolled as healthy controls (HCs), rheumatoid arthritis (RA) patients, or spondyloarthropathy (SpA) patients. Bilateral PTT and PBT entheses were imaged longitudinally, comparing 2 angles of insonation: perpendicular to the skin surface and 45° cephalad. Images were scored on semiquantitative scales assessing pathology.A total of 78 subjects were enrolled (37 HC, 21 RA, and 20 SpA). Complete enthesis visualization was achieved more frequently in the perpendicular than in the cephalad

2016 Arthritis care & research

269. The Effectiveness of Exergames in Patients with Ankylosing Spondylitis: A Randomized Controlled Trial. Full Text available with Trip Pro

) questionnaire.A statistically significant improvement was observed in VAS, BASFI, BASDAI and ASQoL scores in the EG group after completion of the exercise program (p < 0.05).This study is a first step in investigating the possibilities of using an exergame platform to help patients with spondyloarthropathies to adopt a more physically active lifestyle. The results of this study suggest that exergames increase physical activity and decrease the pain scores in AS patients and also could, therefore, be feasible

2016 Advances in clinical and experimental medicine : official organ Wroclaw Medical University Controlled trial quality: uncertain

270. Ocular manifestations of inflammatory bowel disease. (Abstract)

dysbiosis, have been implicated in the pathogenesis of IBD. IBD and its EIMs appear to respond well to TNFα-targeted biologics.IBD is thought to be caused by polygenic and environmental influences, including a dysbiotic gut microbiota. It is a systemic immune-mediated disease with varying types of ocular manifestations that can precede, occur simultaneously, or follow intestinal involvement. The diagnosis of IBD can be confused with other seronegative spondyloarthropathies as well as Behçet's disease

2016 Current Opinion in Ophthalmology

271. Analysis of HLA-B15 and HLA-B27 in spondyloarthritis with peripheral and axial clinical patterns. Full Text available with Trip Pro

to European Spondyloarthropathy Study Group (ESSG) criteria. Patients were then classified according to ASAS criteria, the axial spondyloarthritis pattern (axSpA) being defined by ascertained sacroiliitis and the peripheral pattern (pSpA) by enthesitis and/or arthritis in extremities. A combined ax/p pattern was also considered.Only HLA-B27 and HLA-B15 alleles were associated with SpA. ASAS criteria for axSpA were met in 152 patients (12 with isolated axSpA and 140 with a combined ax/p patterns). When

2015 BMJ open

272. 'MHC-I-opathy'-unified concept for spondyloarthritis and Behçet disease. (Abstract)

'MHC-I-opathy'-unified concept for spondyloarthritis and Behçet disease. The spondyloarthropathies comprise ankylosing spondylitis (AS), reactive arthritis, psoriatic arthritis (PsA) and arthritis associated with inflammatory bowel disease. In this Perspectives article, we describe how Behçet disease and several clinically distinct spondyloarthropathies-all associated with MHC class I (MHC-I) alleles such as HLA-B(*)51, HLA-C(*)0602 and HLA-B(*)27 and epistatic ERAP-1 interactions-have a shared

2015 Nature reviews. Rheumatology

273. Genetics of ankylosing spondylitis-insights into pathogenesis. (Abstract)

Genetics of ankylosing spondylitis-insights into pathogenesis. Ankylosing spondylitis (AS), an immune-mediated arthritis, is the prototypic member of a group of conditions known as spondyloarthropathies that also includes reactive arthritis, psoriatic arthritis and enteropathic arthritis. Patients with these conditions share a clinical predisposition for spinal and pelvic joint dysfunction, as well as genetic associations, notably with HLA-B(*)27. Spondyloarthropathies are characterized

2015 Nature reviews. Rheumatology

274. The intestinal microbiome in human disease and how it relates to arthritis and spondyloarthritis. (Abstract)

The intestinal microbiome in human disease and how it relates to arthritis and spondyloarthritis. Humans and microbes have developed a symbiotic relationship over time, and alterations in this symbiotic relationship have been linked to several immune mediated diseases such as inflammatory bowel disease, type 1 diabetes and spondyloarthropathies. Improvements in sequencing technologies, coupled with a renaissance in 16S rRNA gene based community profiling, have enabled the characterization (...) in the pathogenesis of spondyloarthropathies, and how this may relate to potential therapies for these conditions. Copyright © 2015 Elsevier Ltd. All rights reserved.

2015 Best practice & research. Clinical rheumatology

275. ASAS40 and ASDAS clinical responses in the ABILITY-1 clinical trial translate to meaningful improvements in physical function, health-related quality of life and work productivity in patients with non-radiographic axial spondyloarthritis. Full Text available with Trip Pro

-radiographic axial SpA (nr-axSpA).Data are from ABILITY-1, a phase 3 trial of adalimumab vs placebo in nr-axSpA patients. PROs included the HAQ for Spondyloarthropathies (HAQ-S), 36-item Short Form Health Survey (SF-36) physical component summary (PCS) score and Work Productivity and Activity Impairment Questionnaire. Patients were grouped by clinical response using ASAS40 response and ASDAS disease states at week 12. Changes in PROs from baseline to week 12 were compared between groups using analysis

2015 Rheumatology (Oxford, England) Controlled trial quality: uncertain

276. Safety and Efficacy Study of Rexlemestrocel-L in Subjects With Chronic Discogenic Lumbar Back Pain

Symptomatic central vertebral canal stenosis as defined by neurogenic claudication Spondylolisthesis or retrolisthesis Grade 2 and above or Spondylolysis at the index or adjacent level(s) Lumbar spondylitis or other undifferentiated spondyloarthropathy affecting the index disc Spinal deformity defined as lumbar scoliosis with a Cobb angle of the lumbar spine greater than 15 degrees Any fracture of the spine at the index or adjacent levels that has not healed, or clinically compromised vertebral bodies

2015 Clinical Trials

277. Extract of Curcuma Longa Complexed With Phosphatidilcholine(Motore®)in the Treatment of Adults With Knee Osteoarthritis

sterile (bilateral oophorectomy or hysterectomy); concomitant arthropathy that may confuse or interfere with pain assessment or efficacy, including: inflammatory arthropathy (rheumatoid arthritis, systemic lupus erythematosus, spondyloarthropathy, psoriatic arthritis, polymyalgia rheumatic), gouty arthritis, acute episodes of monoarthritis compatible with pseudogout, Paget's disease with involvement of the joint study, history of septic arthritis, avascular necrosis or intra-articular joint studied

2015 Clinical Trials

278. Musculoskeletal Ultrasound in Asymptomatic Hyperuricemia

two years without a clinical diagnosis of gout per American College of Rheumatology criteria30 (appendix A). Patients, of matched gender and age, with normal uric acid levels will serve as controls. Exclusion Criteria: Patients who meet or have met the ACR criteria for Gout, unable to read English, and/or have terminal illness will not be eligible to participate in the study. Patients with a diagnosis of skin psoriasis31, rheumatoid arthritis, or spondyloarthropathies will not be eligible

2015 Clinical Trials

279. Topical Glyceryl Trinitrate (GTN) and Eccentric Exercises in the Treatment of Midportion Achilles Tendinopathy

: Previous corticosteroid injection to the affected tendon in the past 3 months Symptoms of less than 3 months duration Previous use of topical GTN Current use of nitrates, eg: GTN spray, tablet, transdermal patch. Contra-indication to GTN therapy (see section 12.2.3) Current pregnancy, breastfeeding or planning pregnancy VISA-A score > 80 Previous surgery to the affected Achilles tendon Seronegative spondyloarthropathy with Achilles enthesitis Previous performance of a heavy load eccentric exercise

2015 Clinical Trials

280. A Phase 2a Study Evaluating the Safety and Efficacy of ABT-981 in Patients With Erosive Hand Osteoarthritis

mm3 Diagnosis of one or more of the following: Fibromyalgia, Inflammatory arthritis such as rheumatoid arthritis, peripheral seronegative spondyloarthropathy, Psoriatic arthritis, psoriasis, Microcrystalline (including gout and pseudo gout) arthritis affecting the hands, Any OA of the hands due to an infectious origin or acute traumatic episode, secondary OA or OA linked to cartilage and bone dysplasia, Other chronic painful syndromes that could interfere with assessment of pain at the hand(s

2015 Clinical Trials

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