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Spondyloarthropathy

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241. Suitability Of Nitisinone In Alkaptonuria 1 (SONIA 1): an international, multicentre, randomised, open-label, no-treatment controlled, parallel-group, dose-response study to investigate the effect of once daily nitisinone on 24-h urinary homogentisic acid (PubMed)

Suitability Of Nitisinone In Alkaptonuria 1 (SONIA 1): an international, multicentre, randomised, open-label, no-treatment controlled, parallel-group, dose-response study to investigate the effect of once daily nitisinone on 24-h urinary homogentisic acid Alkaptonuria (AKU) is a serious genetic disease characterised by premature spondyloarthropathy. Homogentisate-lowering therapy is being investigated for AKU. Nitisinone decreases homogentisic acid (HGA) in AKU but the dose-response

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2016 Annals of the Rheumatic Diseases

242. The Effectiveness of Exergames in Patients with Ankylosing Spondylitis: A Randomized Controlled Trial. (PubMed)

) questionnaire.A statistically significant improvement was observed in VAS, BASFI, BASDAI and ASQoL scores in the EG group after completion of the exercise program (p < 0.05).This study is a first step in investigating the possibilities of using an exergame platform to help patients with spondyloarthropathies to adopt a more physically active lifestyle. The results of this study suggest that exergames increase physical activity and decrease the pain scores in AS patients and also could, therefore, be feasible

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2016 Advances in clinical and experimental medicine : official organ Wroclaw Medical University

243. Inflammatory arthritis in HIV positive patients: A practical guide. (PubMed)

Inflammatory arthritis in HIV positive patients: A practical guide. Musculoskeletal manifestations of the human immunodeficiency virus (HIV) have been described since the outset of the global HIV epidemic. Articular syndromes that have been described in association with HIV include HIV-associated arthropathy, seronegative spondyloarthropathies (SPA) (reactive arthritis, psoriatic arthritis (PsA) and undifferentiated SPA), rheumatoid arthritis (RA) and painful articular syndrome.We carried out (...) a computer-assisted search of PubMed for the medical literature from January 1981 to January 2015 using the keywords HIV, acquired immune-deficiency syndrome, rheumatic manifestations, arthritis, spondyloarthropathy, anti-TNF and disease modifying antirheumatic drugs. Only English language literature was included and only studies involving adult human subjects were assessed.There are challenges in the management of inflammatory arthritis in patients who are HIV-positive, including difficulties

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2016 BMC Infectious Diseases

244. Whole-Body MR Imaging: Musculoskeletal Applications. (PubMed)

of the axial skeleton, mainly spondyloarthropathies, whole-body MR imaging reveals additional lesions compared with limited axial (lumbar and pelvic) studies, especially in the thoracic spine and thoracic wall, pelvic and shoulder girdles, and peripheral entheses and joints. This article provides an overview of technical aspects of whole-body MR imaging and practical recommendations for the interpretation of whole-body MR imaging studies. It reviews the currently established and potential indications

2016 Radiology

245. Genetic association of ankylosing spondylitis with TBX21 influences T-bet and pro-inflammatory cytokine expression in humans and SKG mice as a model of spondyloarthritis. (PubMed)

in AS pathogenesis is unclear.We assessed the importance of T-bet in disease development and progression in peripheral blood mononuclear cells from 172 AS cases and 83 healthy controls carrying either risk or protective alleles of the peak AS-associated TBX21 single nucleotide polymorphism. Kinetics and localisation of T-bet expression in the SKG mouse model of spondyloarthropathy was examined, along with the impact of Tbx21 knockout on arthritis development in SKG mice.Patients with AS had higher T-bet (...) IFNγ-producing and IL-17-producing CD8+ T cells, in Tbx21-/- compared with wild-type SKG mice.AS-associated variants in TBX21 influence T-bet expression. T-bet+ innate and adaptive immune cells have altered IL-17 and IFNγ, and early activation marker CD69 expression than T-bet cells. This indicates that T-bet is a major component of inflammatory pathways of spondyloarthropathy in humans and mice.Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under

2016 Annals of the Rheumatic Diseases

246. Cardiovascular magnetic resonance in rheumatology: Current status and recommendations for use. (PubMed)

involvement of the cardiovascular system during their course. The International Consensus Group on CMR in Rheumatology was formed in January 2012 aiming to achieve consensus among CMR and rheumatology experts in developing initial recommendations on the current state-of-the-art use of CMR in CTDs. The present report outlines the recommendations of the participating CMR and rheumatology experts with regards to: (a) indications for use of CMR in rheumatoid arthritis, the spondyloarthropathies, systemic

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2016 International journal of cardiology

247. Human Leukocyte Antigen (HLA) B27 Allotype-Specific Binding and Candidate Arthritogenic Peptides Revealed through Heuristic Clustering of Data-independent Acquisition Mass Spectrometry (DIA-MS) Data (PubMed)

Human Leukocyte Antigen (HLA) B27 Allotype-Specific Binding and Candidate Arthritogenic Peptides Revealed through Heuristic Clustering of Data-independent Acquisition Mass Spectrometry (DIA-MS) Data Expression of HLA-B27 is strongly associated with ankylosing spondylitis (AS) and other spondyloarthropathies. While this is true for the majority of HLA-B27 allotypes, HLA-B*27:06 and HLA-B*27:09 are not associated with AS. These two subtypes contain polymorphisms that are ideally positioned

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2016 Molecular & cellular proteomics : MCP

248. Imaging studies in patients with spinal pain: Practice audit evaluation of Choosing Wisely Canada recommendations (PubMed)

. In these 110 participants, there were newly diagnosed cases of radiculopathy (n = 12), including a case of cauda equina syndrome; spondyloarthropathy (n = 6); occult fracture (n = 2); solitary metastasis (n = 1); epidural lipomatosis (n = 1); osteomyelitis (n = 1), and retroperitoneal hematoma (n = 1), each of which was considered likely to be the cause of the patient's spinal symptoms. The remaining 893 participants were followed for at least 1 year and none showed evidence of a nonbenign cause of his

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2016 Canadian Family Physician

249. Role of ultrasonography in the diagnosis of rheumatic diseases in light of ACR/EULAR guidelines (PubMed)

an alternative to clinical assessment. Moreover, the relevance of ultrasonography in the diagnosis and monitoring of peripheral spondyloarthropathies was widely discussed in 2014 during the meeting of the European League Against Rheumatism in Paris.

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2016 Journal of Ultrasonography

250. Efficacy of radiation synovectomy (radiosynovectomy or radiosynoviorthesis) with yttrium-90 in exudative inflammation of synovial membrane of knee joints in patients with rheumatic diseases – preliminary report (PubMed)

application of colloidal solution to joint cavities. In this study, the authors assessed the efficacy of knee radiosynovectomy with yttrium-90 (Y-90) in several groups of patients divided into certain rheumatic diseases.The study group consisted of 70 patients aged from 29 to 65 years with hypertrophic and exudative synovitis of the knee in rheumatic diseases such as rheumatoid arthritis, osteoarthrosis and spondyloarthropathies. Radiopharmaceutical colloid of Y-90, with a radiation dose of 185-222 MBq

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2016 Reumatologia

251. Facing Terminal Ileitis: Going Beyond Crohn’s Disease (PubMed)

, medical approach and patient care. This work was performed on a survey of articles collected in different databases and a retrospective search was carried out to identify relevant studies in the field. Pathological conditions such as ulcerative colitis, the intake of non-steroidal anti-inflammatory drugs, infectious diseases, eosinophilic enteritis, malignant diseases, spondyloarthropathies, vasculitides, ischemia, sarcoidosis, amyloidosis and others may be related to ileitis but it is commonly

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2016 Gastroenterology research

252. Rheumatologic Disease

Disorders CREST Syndrome IV. Causes: Joint Disorder Crystal (CPPD) V. Causes: Myofacial Conditions Myofacial Pain Syndrome VI. Causes: Spondyloarthropathy (e.g. ) VII. Causes: Miscellaneous Ehlers-Danlos Syndrome Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Rheumatologic Disease." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Collagen Diseases

2018 FP Notebook

253. Reiter's Syndrome

) , artritis postinfecciosa , artritis que ocurre después de una infección , artropatía posbacteriana (trastorno) , artropatía posbacteriana , artropatía postinfecciosa , Artritis reactiva , Artritis Postinfecciosa , Artritis Reactiva Portuguese Artrite reactiva , Artrite Pós-Infecciosa , Artrite Reativa Derived from the NIH UMLS ( ) Related Topics in Spondyloarthropathy About FPnotebook.com is a rapid access, point-of-care medical reference for primary care and emergency clinicians. Started in 1995

2018 FP Notebook

254. Ankylosing Spondylitis

costovertebral mobility Apical lobe fibrosis Neurologic Involvement Spine s or dislocations Atlantoaxial subluxation VI. Complications of Late Spondyloarthropathy Spondylodiscitis Pseudoarthrosis with spinal cord compression Resultant neurologic deficits VII. Exam Observation of back Lumbar lordosis flattened Thoracic kyphosis exaggerated hyperextended Tests for Sacroiliac Joint Inflammation Tests for range of motion loss at Decreased lateral bending and lumbar extension VIII. Radiology Anteroposterior (...) ankylosans Korean 청소년성 강직성 척추염 Spanish espondilitis anqulilosante juvenil , espondilitis anqulilosante juvenil (trastorno) , espondilitis anquilosante juvenil , espondilitis anquilosante juvenil (trastorno) Dutch ankylopoetica; spondylitis, juveniel , juveniel ankyloserend; spondylitis , spondylitis; ankylopoetica, juveniel , spondylitis; juveniel ankyloserend , Juveniele spondylitis ankylopoetica Derived from the NIH UMLS ( ) Related Topics in Spondyloarthropathy About FPnotebook.com is a rapid access

2018 FP Notebook

255. Longterm Efficacy of an Antipneumococcal Polysaccharide Vaccine among Patients with Autoimmune Inflammatory Rheumatic Diseases. (PubMed)

Longterm Efficacy of an Antipneumococcal Polysaccharide Vaccine among Patients with Autoimmune Inflammatory Rheumatic Diseases. To estimate the longterm humoral response of an antipneumococcal polysaccharide vaccine (PPSV23) in patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), or inflammatory bowel disease (IBD)-associated spondyloarthropathy (SpA), and the effect of demographic and clinical factors and treatment on the longterm efficacy

2016 Journal of Rheumatology

256. Assessment of Fatigue in Spondyloarthritis and Its Association with Disease Activity. (PubMed)

Assessment of Fatigue in Spondyloarthritis and Its Association with Disease Activity. To evaluate fatigue in patients with spondyloarthritis (SpA) and to define its association with disease-related factors and patients' features.A cross-sectional multicenter study which includes 2251 patients with SpA selected from the national Spondyloarthropathies Registry (the Spanish Society of Rheumatology; REGISPONSER) Spanish cohort. The primary outcome was the assessment of fatigue performed

2016 Journal of Rheumatology

257. Ocular manifestations of inflammatory bowel disease. (PubMed)

dysbiosis, have been implicated in the pathogenesis of IBD. IBD and its EIMs appear to respond well to TNFα-targeted biologics.IBD is thought to be caused by polygenic and environmental influences, including a dysbiotic gut microbiota. It is a systemic immune-mediated disease with varying types of ocular manifestations that can precede, occur simultaneously, or follow intestinal involvement. The diagnosis of IBD can be confused with other seronegative spondyloarthropathies as well as Behçet's disease

2016 Current Opinion in Ophthalmology

258. Gut microbiome in children with enthesitis‐related arthritis in a developing country and the effect of probiotic administration (PubMed)

Gut microbiome in children with enthesitis‐related arthritis in a developing country and the effect of probiotic administration In Asia, enthesitis-related arthritis (ERA) is the most frequent category of juvenile idiopathic arthritis. ERA has a strong association with human leucocyte antigen (HLA)-B27 and subclinical gut inflammation. In an HLA-B27 transgenic rat model, the presence of Bacteroides bacteria in the gut appears to cause spondyloarthropathy (SpA). Thus, we studied gut microbiota

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2016 Clinical and experimental immunology

259. Enthesitis in a 16-Year-Old Boy with M694V Mutation (PubMed)

Enthesitis in a 16-Year-Old Boy with M694V Mutation Introduction. FMF (Familial Mediterranean Fever) is characterized by recurrent attacks of fever and articular pain. Enthesitis is the hallmark of pain in spondyloarthropathy. Literature suggests association of M694V mutation and enthesitis. We report a case of a 16-year-old boy with enthesitis and FMF. Case Presentation. A 16-year-old boy of Turkish origin with a history of FMF presented with localized tenderness of the heel and severe

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2016 Case reports in medicine

260. Selected issues in diagnostic imaging of spondyloarthritides: psoriatic arthritis and juvenile spondyloarthritis (PubMed)

Selected issues in diagnostic imaging of spondyloarthritides: psoriatic arthritis and juvenile spondyloarthritis Spondyloarthritides (also known as spondyloarthropathies) are a group of rheumatic diseases that consists of diversified entities, i.e. ankylosing spondylitis, reactive arthritis, psoriatic arthritis, arthritis in the course of Crohn's disease and ulcerative colitis, and juvenile spondyloarthropathies. In the diagnostics of spondyloarthritides, plain radiography has played a crucial

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2016 Reumatologia

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