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241. Human Leukocyte Antigen (HLA) B27 Allotype-Specific Binding and Candidate Arthritogenic Peptides Revealed through Heuristic Clustering of Data-independent Acquisition Mass Spectrometry (DIA-MS) Data Full Text available with Trip Pro

Human Leukocyte Antigen (HLA) B27 Allotype-Specific Binding and Candidate Arthritogenic Peptides Revealed through Heuristic Clustering of Data-independent Acquisition Mass Spectrometry (DIA-MS) Data Expression of HLA-B27 is strongly associated with ankylosing spondylitis (AS) and other spondyloarthropathies. While this is true for the majority of HLA-B27 allotypes, HLA-B*27:06 and HLA-B*27:09 are not associated with AS. These two subtypes contain polymorphisms that are ideally positioned

2016 Molecular & cellular proteomics : MCP

242. Gut microbiome in children with enthesitis‐related arthritis in a developing country and the effect of probiotic administration Full Text available with Trip Pro

Gut microbiome in children with enthesitis‐related arthritis in a developing country and the effect of probiotic administration In Asia, enthesitis-related arthritis (ERA) is the most frequent category of juvenile idiopathic arthritis. ERA has a strong association with human leucocyte antigen (HLA)-B27 and subclinical gut inflammation. In an HLA-B27 transgenic rat model, the presence of Bacteroides bacteria in the gut appears to cause spondyloarthropathy (SpA). Thus, we studied gut microbiota

2016 Clinical and experimental immunology

243. Selected issues in diagnostic imaging of spondyloarthritides: psoriatic arthritis and juvenile spondyloarthritis Full Text available with Trip Pro

Selected issues in diagnostic imaging of spondyloarthritides: psoriatic arthritis and juvenile spondyloarthritis Spondyloarthritides (also known as spondyloarthropathies) are a group of rheumatic diseases that consists of diversified entities, i.e. ankylosing spondylitis, reactive arthritis, psoriatic arthritis, arthritis in the course of Crohn's disease and ulcerative colitis, and juvenile spondyloarthropathies. In the diagnostics of spondyloarthritides, plain radiography has played a crucial

2016 Reumatologia

244. Radionuclide synovectomy – essentials for rheumatologists Full Text available with Trip Pro

Radionuclide synovectomy – essentials for rheumatologists Radionuclide synovectomy is a minimally invasive method of treating persistent joint inflammation. It involves intra-articular injection of radioactive colloids which induce necrosis and fibrosis of hypertrophic synovial membrane. The most common indication for radiosynovectomy is rheumatoid arthritis, although patients with seronegative spondyloarthropathies, unclassified arthritis, haemophilic arthropathy and other less common

2016 Reumatologia

245. Rate and Predisposing Factors for Sacroiliac Joint Radiographic Progression After a Two‐Year Follow‐up Period in Recent‐Onset Spondyloarthritis Full Text available with Trip Pro

Rate and Predisposing Factors for Sacroiliac Joint Radiographic Progression After a Two‐Year Follow‐up Period in Recent‐Onset Spondyloarthritis To evaluate the rate of radiographic structural progression in the sacroiliac (SI) joints in patients with radiographic or nonradiographic axial spondyloarthritis (SpA), and to determine factors predisposing to such progression, over 2 years.Patients with recent-onset axial SpA (from the Devenir des Spondyloarthropathies Indifferérenciées Récentes

2016 Arthritis & rheumatology (Hoboken, N.J.)

246. Functional limitations due to foot involvement in spondyloarthritis Full Text available with Trip Pro

and psoriatic arthritis with foot pain more than 4 weeks who underwent anteroposterior and lateral feet radiography were enrolled into the study. A "clinical findings score" was calculated by assigning 1 point for every finding of swelling, redness, and tenderness. C-reactive protein and erythrocyte sedimentation rate were used as serum markers for disease activity. Foot radiograms were evaluated using the spondyloarthropathy tarsal radiographic index and the foot-related functional state of patients

2016 Journal of physical therapy science

247. Coexistence of a Ghon Complex, Pott’s Disease, and Hip Arthritis in a Child Full Text available with Trip Pro

and hip arthritis in a patient who recovered after 12 months of antituberculosis therapy.A 16-year-old girl presented to the outpatient otolaryngology clinic with painless swelling of the neck, and to the physical medicine and rehabilitation clinic with complaints of hip and low back pain that mimicked spondyloarthropathy. She was eventually referred to the outpatient pediatric clinic. Her acute-phase reactants were high, and hilar lymphadenopathy was evident on chest x-ray. On computerized tomography

2016 Iranian Red Crescent medical journal

248. Facing Terminal Ileitis: Going Beyond Crohn’s Disease Full Text available with Trip Pro

, medical approach and patient care. This work was performed on a survey of articles collected in different databases and a retrospective search was carried out to identify relevant studies in the field. Pathological conditions such as ulcerative colitis, the intake of non-steroidal anti-inflammatory drugs, infectious diseases, eosinophilic enteritis, malignant diseases, spondyloarthropathies, vasculitides, ischemia, sarcoidosis, amyloidosis and others may be related to ileitis but it is commonly

2016 Gastroenterology research

249. Clinical Characteristics of Importance to Outcome in Patients With Spondyloarthritis

Collaborators: Odense University Hospital Parker Research Institute Spine Centre of Southern Denmark Information provided by (Responsible Party): Rikke Asmussen Andreasen, Svendborg Hospital Study Details Study Description Go to Brief Summary: The objective of the study is to investigate extra-articular manifestations, pain mechanisms, patient-reported outcomes, comorbidities and association between these conditions in patients with spondyloarthropathy (SpA) treated with Biologics. Further, to assess (...) the predictive value of baseline pain profile on treatment outcome after ≥ 3 months. Condition or disease Spondyloarthropathy Detailed Description: Patients with spondyloarthropaty, who initiate or switch biologics in routine care due to an active disease state, will be enrolled in this observational study. The overall aim is to investigate extra-articular manifestations, pain mechanisms and patient-reported outcomes and elucidate if these factors - independently or by interaction - influence treatment

2016 Clinical Trials

250. Post Approval Study of Lixelle for the Treament of Dialysis-Related Amyloidosis

syndrome (3) Trigger finger (4) Dialysis-associated spondylosis ((i) or (ii)) (i) Destructive spondyloarthropathy (DSA) (ii) Spinal stenosis (5) Bone cysts (Bone cysts considered to be caused by other diseases such as osteoarthritis, aneurysmal bone cysts and unicameral bone cysts should be excluded.) Biopsy of any tissue, showing Congo-red positive amyloid fibrils, and one diagnosis or surgical history of criterion 3- (1) to (5) Exclusion Criteria: Patient who meets any of the following 1 to 7

2016 Clinical Trials

251. Ultrasound as Imaging Biomarker of Early Response to Tocilizumab and Methotrexate in Very Early Rheumatoid Arthritis

, leflunomide, sulphasalazine) and naïve to any biologics or biosimilars. Exclusion Criteria: History of other concomitant autoimmune disease such as lupus or psoriatic arthritis Meeting diagnostic criteria for any other rheumatic disease than RA (e.g. gout, Lyme disease, seronegative spondyloarthropathy including reactive arthritis, psoriatic arthritis, arthropathy or inflammatory bowel disease) Any previous treatment with : Biologics: Etanercept, infliximab, certolizumab, golimumab, abatacept, adalimumab

2016 Clinical Trials

252. A Study of the Use of the Madrid Ultrasound Scoring System in the Treatment of Anti-TNF Blocker to Peripheral Tendonitis in Patients With Spondyloarthritis

the blind stage would finish the study. Condition or disease Intervention/treatment Phase Spondyloarthropathy Drug: etanercept Drug: etanercept (half dose) Drug: placebo Phase 4 Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 96 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) Primary Purpose: Treatment Official Title (...) Identifier: Other Study ID Numbers: [2015]2-158 First Posted: November 9, 2016 Last Update Posted: November 9, 2016 Last Verified: November 2016 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: Yes Plan Description: The data will be published on the Journals. Keywords provided by Gu Jieruo, Sun Yat-sen University: Mardird sonographic enthesis index Spondyloarthropathy Ultrasonics Etanercept Additional relevant MeSH terms: Layout table for MeSH terms Spondylarthritis

2016 Clinical Trials

253. Uveitis

is not known; when a cause is identified, it usually includes one of the following [ ; ; ]: Systemic autoimmune disorders, such as: Seronegative spondyloarthropathies (ankylosing spondylitis, juvenile rheumatoid arthritis, Reiter's syndrome, and inflammatory bowel disease). Behçet's disease. Sarcoidosis. Psoriasis (with or without associated arthritis). Multiple sclerosis. Infection. Common infectious causes are herpes simplex, varicella zoster virus, cytomegalovirus, and toxoplasmosis. Less common

2014 NICE Clinical Knowledge Summaries

254. Prospective Study Evaluating the Use of PROSPECT to Reduce Insomnia in Patients With Early Stage Breast Cancer

taken for insomnia (melatonin, benzodiazepines, antihistamines, etc.) for < 4 weeks prior to enrollment in the study Use of medication for treatment of another sleep disorder, such as restless leg syndrome or narcolepsy History of medial or arthritic disease that could confound or interfere with evaluation of activity level, including but not limited to inflammatory arthritis (Rheumatoid Arthritis, Systemic Lupus Spondyloarthropathy, Psoriatic Arthritis, Polymyalgia Rheumatica), Parkinson's disease

2016 Clinical Trials

255. Biopsychosocial Exploration of Pain Profiles in Inflammatory and Chronic Non-specific Axial Low Back Pain

criteria for CNSLBP group: Spondyloarthropathy, or any structural abnormalities in the lumbar spine that result in serious neurological dysfunction, such as stage III-IV lumbar disc herniation, and grade III-IV spondylolisthesis Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its

2016 Clinical Trials

256. A Study of the Safety and Effectiveness of the Mentor Larger Size MemoryGel Ultra High Profile Breast Implants in Subjects Who Are Undergoing Primary Breast Reconstruction or Revision Reconstruction

, infectious arthritis, spondyloarthropathies, any other inflammatory arthritis, fibromyalgia, or chronic fatigue syndrome Currently has a condition that could compromise or complicate wound healing. Note, obesity alone is not an exclusion. All surgical risk factors (obesity, diabetes, smoking history, and prior radiation) should be considered in totality for proper subject selection Infection or abscess anywhere in the body Demonstrates tissue characteristics that are clinically incompatible

2016 Clinical Trials

257. Prediction of the Answer to the Treatment by Biotherapies for Naive Spondyloarthritis by Combinatorial Analysis of Serum Biomarkers

important for etanercept treatment. Condition or disease Intervention/treatment Phase Spondylitis, Ankylosing Drug: Etanercept ® 50 mg Not Applicable Detailed Description: Spondyloarthritis (or spondyloarthropathy) is an inflammatory rheumatic disease that causes arthritis. It differs from other types of arthritis because it involves the sites where ligaments and tendons are attached to bones called "entheses." All patients should get physical therapy and make exercises for joints. Exercises

2016 Clinical Trials

258. To Evaluate the Superiority of Fixed Combination (Orfenadrine 35mg, Acetaminophen 325mg, Caffeine 65mg and Diclofenac Sodium 50mg) Compared to Voltaren® (Diclofenac Sodium 50mg) in the Treatment of Acute Postural Low Back Pain.

; as well as participants with a history of bacterial infection that affected the spine in a chronic way; Research participants previously diagnosed with herniated disc, osteoid osteoma, arthroscopic narrowing of the spinal canal, spondyloarthropathies, spondylodiscites, renal calculus, calculitic cholecystitis, endometriosis, prostatitis, abdominal aortic aneurysm, chronic pelvic pain, pyelonephritis, perirenal abscesses and pancreatitis , rheumatoid arthritis, systemic lupus erythematosus, psoriatic

2016 Clinical Trials

259. Inflammatory Back Pain and Gluten Free Diet

): Pasquale Mansueto, University of Palermo Study Details Study Description Go to Brief Summary: Articular involvement is the most frequent extra-intestinal manifestation of inflammatory bowel diseases (IBD). IBD-related spondyloarthropathy is mainly characterised by axial involvement (including inflammatory back pain, isolated sacroiliitis and ankylosing spondylitis) but may also be associated with peripheral symptoms (i.e peripheral arthritis, dactylitis and enthesopathy, such as Achilles tendinitis

2016 Clinical Trials

260. VCRC Longitudinal Protocol for Aortitis

, and spondyloarthropathies, among others. This study will establish a longitudinal cohort for these diseases. Condition or disease Aortitis Detailed Description: This study will develop a longitudinal cohort of patients with different types of aortitis to systematically study the natural history, optimal treatments, and outcomes in this group of diseases. This will provide a resource for future studies and for identification of new biomarkers of aortitis for purposes of diagnosis, disease activity measurement, disease

2016 Clinical Trials

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