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221. PK, PD, Safety, and Efficacy of SAIT101 Versus MabThera® Versus Rituxan® in Patients With Rheumatoid Arthritis

/bed bound. History of or current inflammatory joint disease other than RA (including but not limited to gout, reactive arthritis, psoriatic arthritis, seronegative spondyloarthropathy or Lyme disease). History of or current systemic autoimmune disorder (including but not limited to systemic lupus erythematosus, inflammatory bowel disease, pulmonary fibrosis, Felty syndrome, scleroderma, inflammatory myopathy, fibromyalgia, juvenile idiopathic arthritis, mixed connective tissue disease, vasculitis

2016 Clinical Trials

222. Evaluation of the Evolution of Imaging Markers of Cartilage Degradation in Patients With Knee Osteoarthritis Receiving DROGLICAN

interfering with the evaluation of OA and/or pain such as articular dysplasia, aseptic osteonecrosis, acromegaly, Paget's disease, hemophilia, hemochromatosis, chondromatosis, villonodular synovitis of the knee, seronegative spondyloarthropathy, rheumatoid arthritis, gouty arthritis , infectious arthritis, radiculalgia in the lower limbs, arteritis, etc. Radiological K&L grade I or IV Prosthesis in the target knee Related to treatments Analgesics to manage OA knee pain 24h before inclusion visit

2016 Clinical Trials

223. Ultrasound as Imaging Biomarker of Early Response to Tocilizumab and Methotrexate in Very Early Rheumatoid Arthritis

, leflunomide, sulphasalazine) and naïve to any biologics or biosimilars. Exclusion Criteria: History of other concomitant autoimmune disease such as lupus or psoriatic arthritis Meeting diagnostic criteria for any other rheumatic disease than RA (e.g. gout, Lyme disease, seronegative spondyloarthropathy including reactive arthritis, psoriatic arthritis, arthropathy or inflammatory bowel disease) Any previous treatment with : Biologics: Etanercept, infliximab, certolizumab, golimumab, abatacept, adalimumab

2016 Clinical Trials

224. A Study of the Use of the Madrid Ultrasound Scoring System in the Treatment of Anti-TNF Blocker to Peripheral Tendonitis in Patients With Spondyloarthritis

the blind stage would finish the study. Condition or disease Intervention/treatment Phase Spondyloarthropathy Drug: etanercept Drug: etanercept (half dose) Drug: placebo Phase 4 Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 96 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) Primary Purpose: Treatment Official Title (...) Identifier: Other Study ID Numbers: [2015]2-158 First Posted: November 9, 2016 Last Update Posted: November 9, 2016 Last Verified: November 2016 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: Yes Plan Description: The data will be published on the Journals. Keywords provided by Gu Jieruo, Sun Yat-sen University: Mardird sonographic enthesis index Spondyloarthropathy Ultrasonics Etanercept Additional relevant MeSH terms: Layout table for MeSH terms Spondylarthritis

2016 Clinical Trials

225. C.O.R.P.U.S.: Observational Cohort of Adult and Child Inflammatory Arthritis in France

table for eligibility information Ages Eligible for Study: 3 Years to 75 Years (Child, Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Sampling Method: Non-Probability Sample Study Population Patients suffering rheumatoid arthritis, spondyloarthropathy or idiopathic juvenile arthritis, recruited with rheumatologist in public and private practice Criteria Inclusion Criteria: Diagnosis by rheumatologist of rheumatoid arthritis DAS score > 3.2, any age of onset hand

2016 Clinical Trials

226. To Evaluate the Superiority of Fixed Combination (Orfenadrine 35mg, Acetaminophen 325mg, Caffeine 65mg and Diclofenac Sodium 50mg) Compared to Voltaren® (Diclofenac Sodium 50mg) in the Treatment of Acute Postural Low Back Pain.

; as well as participants with a history of bacterial infection that affected the spine in a chronic way; Research participants previously diagnosed with herniated disc, osteoid osteoma, arthroscopic narrowing of the spinal canal, spondyloarthropathies, spondylodiscites, renal calculus, calculitic cholecystitis, endometriosis, prostatitis, abdominal aortic aneurysm, chronic pelvic pain, pyelonephritis, perirenal abscesses and pancreatitis , rheumatoid arthritis, systemic lupus erythematosus, psoriatic

2016 Clinical Trials

227. Biopsychosocial Exploration of Pain Profiles in Inflammatory and Chronic Non-specific Axial Low Back Pain

criteria for CNSLBP group: Spondyloarthropathy, or any structural abnormalities in the lumbar spine that result in serious neurological dysfunction, such as stage III-IV lumbar disc herniation, and grade III-IV spondylolisthesis Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its

2016 Clinical Trials

228. A Study of the Safety and Effectiveness of the Mentor Larger Size MemoryGel Ultra High Profile Breast Implants in Subjects Who Are Undergoing Primary Breast Reconstruction or Revision Reconstruction

, infectious arthritis, spondyloarthropathies, any other inflammatory arthritis, fibromyalgia, or chronic fatigue syndrome Currently has a condition that could compromise or complicate wound healing. Note, obesity alone is not an exclusion. All surgical risk factors (obesity, diabetes, smoking history, and prior radiation) should be considered in totality for proper subject selection Infection or abscess anywhere in the body Demonstrates tissue characteristics that are clinically incompatible

2016 Clinical Trials

229. Clinical Characteristics of Importance to Outcome in Patients With Spondyloarthritis

Collaborators: Odense University Hospital Parker Research Institute Spine Centre of Southern Denmark Information provided by (Responsible Party): Rikke Asmussen Andreasen, Svendborg Hospital Study Details Study Description Go to Brief Summary: The objective of the study is to investigate extra-articular manifestations, pain mechanisms, patient-reported outcomes, comorbidities and association between these conditions in patients with spondyloarthropathy (SpA) treated with Biologics. Further, to assess (...) the predictive value of baseline pain profile on treatment outcome after ≥ 3 months. Condition or disease Spondyloarthropathy Detailed Description: Patients with spondyloarthropaty, who initiate or switch biologics in routine care due to an active disease state, will be enrolled in this observational study. The overall aim is to investigate extra-articular manifestations, pain mechanisms and patient-reported outcomes and elucidate if these factors - independently or by interaction - influence treatment

2016 Clinical Trials

230. Post Approval Study of Lixelle for the Treament of Dialysis-Related Amyloidosis

syndrome (3) Trigger finger (4) Dialysis-associated spondylosis ((i) or (ii)) (i) Destructive spondyloarthropathy (DSA) (ii) Spinal stenosis (5) Bone cysts (Bone cysts considered to be caused by other diseases such as osteoarthritis, aneurysmal bone cysts and unicameral bone cysts should be excluded.) Biopsy of any tissue, showing Congo-red positive amyloid fibrils, and one diagnosis or surgical history of criterion 3- (1) to (5) Exclusion Criteria: Patient who meets any of the following 1 to 7

2016 Clinical Trials

231. FDG PET/MRI Evaluation of Facet Joint Pain

spondyloarthropathies and myopathies, but is also lacking. This is an exploratory study investigating the utility of FDG PET activity and MRI signal change around facet joints in the clinical management of low back pain. This study will help determine if such imaging biomarkers could change clinical management. Additionally, this will provide data that will be vital to planning a larger prospective study evaluating the ability of imaging biomarkers to predict response to comparison medial branch blocks and RF

2016 Clinical Trials

232. Development of the General Scale Observance for Chronic Diseases

Criteria: patient age of 18 years from routine patient counseling with at least one of these diseases : heart failure, hypertension, coronary disease, type 2 diabetes, osteoarthritis of the knee or hip, osteoporosis, inflammatory rheumatism (rheumatoid arthritis, spondyloarthropathy), cancer ( with only non-hormonal oral anti cancer treatments) and HIV. patient can read the French language in order to complete the self -administered questionnaire patient agreeing to participate in the study Exclusion

2016 Clinical Trials

233. VCRC Longitudinal Protocol for Aortitis

, and spondyloarthropathies, among others. This study will establish a longitudinal cohort for these diseases. Condition or disease Aortitis Detailed Description: This study will develop a longitudinal cohort of patients with different types of aortitis to systematically study the natural history, optimal treatments, and outcomes in this group of diseases. This will provide a resource for future studies and for identification of new biomarkers of aortitis for purposes of diagnosis, disease activity measurement, disease

2016 Clinical Trials

234. Inflammatory Back Pain and Gluten Free Diet

): Pasquale Mansueto, University of Palermo Study Details Study Description Go to Brief Summary: Articular involvement is the most frequent extra-intestinal manifestation of inflammatory bowel diseases (IBD). IBD-related spondyloarthropathy is mainly characterised by axial involvement (including inflammatory back pain, isolated sacroiliitis and ankylosing spondylitis) but may also be associated with peripheral symptoms (i.e peripheral arthritis, dactylitis and enthesopathy, such as Achilles tendinitis

2016 Clinical Trials

235. Prediction of the Answer to the Treatment by Biotherapies for Naive Spondyloarthritis by Combinatorial Analysis of Serum Biomarkers

important for etanercept treatment. Condition or disease Intervention/treatment Phase Spondylitis, Ankylosing Drug: Etanercept ® 50 mg Not Applicable Detailed Description: Spondyloarthritis (or spondyloarthropathy) is an inflammatory rheumatic disease that causes arthritis. It differs from other types of arthritis because it involves the sites where ligaments and tendons are attached to bones called "entheses." All patients should get physical therapy and make exercises for joints. Exercises

2016 Clinical Trials

236. A Pilot Study of MSCs Iufusion and Etanercept to Treat Ankylosing Spondylitis

anti-TNF therapy within 3 months pregnant or suckling period female patients; Patients with the Medical or mentally imbalance charged by researchers. patients associated cardiovascular, cerebrovascular, liver,renal and hematological system diseases or mental disease; Patients could not accept the research or could not cooperate well. Patients with other sever diseases at the same time, such as abnormality of joints, other seronegative spondyloarthropathy, or other Rheumatic Diseases. Contacts

2016 Clinical Trials

237. Clinical Performance of B-Lite® Light Weight Breast Implant

, if medically required The patient has a confirmed rheumatic disease or syndrome (e.g., SLE, Sjogren's syndrome, scleroderma, polymyositis or any connective tissue disorder, rheumatoid arthritis, crystalline arthritis, infectious arthritis, spondyloarthropathies, any other inflammatory arthritis, fibromyalgia or chronic fatigue syndrome) The patient has a severe breast and upper trunk deformity The patient participated in an investigational trial within 90 days of enrollment The patient has undergone

2016 Clinical Trials

238. Prospective Study Evaluating the Use of PROSPECT to Reduce Insomnia in Patients With Early Stage Breast Cancer

taken for insomnia (melatonin, benzodiazepines, antihistamines, etc.) for < 4 weeks prior to enrollment in the study Use of medication for treatment of another sleep disorder, such as restless leg syndrome or narcolepsy History of medial or arthritic disease that could confound or interfere with evaluation of activity level, including but not limited to inflammatory arthritis (Rheumatoid Arthritis, Systemic Lupus Spondyloarthropathy, Psoriatic Arthritis, Polymyalgia Rheumatica), Parkinson's disease

2016 Clinical Trials

239. Systematic review of rheumatic disease phenotypes and outcomes in the Indigenous populations of Canada, the USA, Australia and New Zealand. (Full text)

on patient-reported outcomes and quality of life than non-Indigenous patients. Spondyloarthropathy features were described in North American populations, with most patients having advanced manifestations. In systemic lupus erythematosus, nephritis was more frequent in Indigenous populations. Gout and osteoarthritis were more severe in New Zealand Maori populations. The existing literature supports differences in disease phenotype and severity in Indigenous populations of Canada, America, Australia

2016 Rheumatology international PubMed

240. The role of the gastrointestinal tract in the pathogenesis of rheumatic diseases. (Full text)

The role of the gastrointestinal tract in the pathogenesis of rheumatic diseases. Dysregulation of the intestinal epithelial barrier in genetically susceptible individuals may lead to both intestinal and extraintestinal autoimmune disorders. There is emerging literature on the role of microbiota changes in the pathogenesis of systemic rheumatic diseases such as rheumatoid arthritis, spondyloarthropathies, and connective tissue diseases. Although the role of the gastrointestinal tract

2016 Best practice & research. Clinical rheumatology PubMed

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