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Spondyloarthropathy

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201. What is hidradenitis suppurativa? (PubMed)

based on typical lesions (nodules, abscesses, sinus tracts), locations (skin folds), and nature of relapses and chronicity. Multiple comorbidities are associated with HS, including obesity, metabolic syndrome, inflammatory bowel disease, and spondyloarthropathy. Although the lack of curative therapy and the recurrent nature makes HS treatment challenging, there are effective symptomatic management options.Family physicians should be suspicious of HS in patients presenting with recurrent skin

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2017 Canadian Family Physician

202. Imaging of juvenile spondyloarthritis. Part I: Classifications and radiographs (PubMed)

Imaging of juvenile spondyloarthritis. Part I: Classifications and radiographs Juvenile spondyloarthropathies are manifested mainly by symptoms of peripheral arthritis and enthesitis. By contrast with adults, children rarely present with sacroiliitis and spondylitis. Imaging and laboratory tests allow early diagnosis and treatment. Conventional radiographs visualize late inflammatory lesions and post-inflammatory complications. Early diagnosis is possible with the use of ultrasonography (...) and magnetic resonance imaging. The first part of the article presents classifications of juvenile spondyloarthropathies and discusses their radiographic presentation. Typical radiographic features of individual types of juvenile spondyloarthritis are listed (including ankylosing spondylitis, juvenile psoriatic arthritis, reactive arthritis and arthritis in the course of inflammatory bowel diseases). The second part will describe changes visible on ultrasonography and magnetic resonance imaging

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2017 Journal of Ultrasonography

203. Imaging of juvenile spondyloarthritis. Part II: Ultrasonography and magnetic resonance imaging (PubMed)

Imaging of juvenile spondyloarthritis. Part II: Ultrasonography and magnetic resonance imaging Juvenile spondyloarthropathies are mainly manifested by symptoms of peripheral arthritis and enthesitis. Early involvement of sacroiliac joints and spine is exceptionally rare in children; this usually happens in adulthood. Conventional radiographs visualize late inflammatory lesions. Early diagnosis is possible with the use of ultrasonography and magnetic resonance imaging. The first part (...) of the article presented classifications and radiographic presentation of juvenile spondyloarthropathies. This part discusses changes seen on ultrasonography and magnetic resonance imaging. In patients with juvenile spondyloarthropathies, these examinations are conducted to diagnose inflammatory lesions in peripheral joints, tendon sheaths, tendons and bursae. Moreover, magnetic resonance also shows subchondral bone marrow edema, which is considered an early sign of inflammation. Ultrasonography and magnetic

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2017 Journal of Ultrasonography

204. Animal models of rheumatoid pain: experimental systems and insights (PubMed)

Animal models of rheumatoid pain: experimental systems and insights Severe chronic pain is one of the hallmarks and most debilitating manifestations of inflammatory arthritis. It represents a significant problem in the clinical management of patients with common chronic inflammatory joint conditions such as rheumatoid arthritis, psoriatic arthritis and spondyloarthropathies. The functional links between peripheral inflammatory signals and the establishment of the neuroadaptive mechanisms acting

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2017 Arthritis research & therapy

207. Chronic Foot Pain

such as the seronegative spondyloarthropathies, rheumatoid arthritis, gout, or systemic lupus erythematosus [28]. In athletes, plantar fasciitis is a common cause of foot pain and is attributed to mechanical stresses, presumably due to repetitive trauma, which causes plantar fascia microtearing at its origin as well as fascial and perifascial inflammation. Plantar fasciitis is also common in obese patients and in patients who have flat feet. Though radiography is typically insensitive to fasciitis, it should

2013 American College of Radiology

209. Health Supervision in the Management of Children and Adolescents With IBD: NASPGHAN Recommendations

assess for ocular findings related to IBD, including uveitis, iritis, and episcleritis. Joint findings can be seen in up to 15% of patients with CD and UC (11). This can range in severity from nonspecific arthralgias, to a migratory nondestructive arthritis typically seen in large joints, to the more severe and debilitating spondyloarthropathies observed most commonly in patients who are HLA-B27 positive. Muscu- loskeletal conditions that clinicians should consider in children with IBD may also

2012 North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition

210. Skeletal Health of Children and Adolescents With Inflammatory Bowel Disease

those observed in adults (164). Importantly, none of these studies related changes in bone markers to subsequent changes in bone mass or structure. One study of adults with CD found significant improvements in BMD measured via DXA, 1 year after treatment with infliximab (165). One prospective study of 19 (17 received infliximab) adults with spondyloarthropathy demon- strated significant increases in lean mass, BMD, and IGF-1 and a decrease in bone resorption markers after 12 months of anti-TNF

2011 North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition

211. Rate and Predisposing Factors for Sacroiliac Joint Radiographic Progression After a Two‐Year Follow‐up Period in Recent‐Onset Spondyloarthritis (PubMed)

Rate and Predisposing Factors for Sacroiliac Joint Radiographic Progression After a Two‐Year Follow‐up Period in Recent‐Onset Spondyloarthritis To evaluate the rate of radiographic structural progression in the sacroiliac (SI) joints in patients with radiographic or nonradiographic axial spondyloarthritis (SpA), and to determine factors predisposing to such progression, over 2 years.Patients with recent-onset axial SpA (from the Devenir des Spondyloarthropathies Indifferérenciées Récentes

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2016 Arthritis & rheumatology (Hoboken, N.J.)

212. Functional limitations due to foot involvement in spondyloarthritis (PubMed)

and psoriatic arthritis with foot pain more than 4 weeks who underwent anteroposterior and lateral feet radiography were enrolled into the study. A "clinical findings score" was calculated by assigning 1 point for every finding of swelling, redness, and tenderness. C-reactive protein and erythrocyte sedimentation rate were used as serum markers for disease activity. Foot radiograms were evaluated using the spondyloarthropathy tarsal radiographic index and the foot-related functional state of patients

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2016 Journal of physical therapy science

213. Radionuclide synovectomy – essentials for rheumatologists (PubMed)

Radionuclide synovectomy – essentials for rheumatologists Radionuclide synovectomy is a minimally invasive method of treating persistent joint inflammation. It involves intra-articular injection of radioactive colloids which induce necrosis and fibrosis of hypertrophic synovial membrane. The most common indication for radiosynovectomy is rheumatoid arthritis, although patients with seronegative spondyloarthropathies, unclassified arthritis, haemophilic arthropathy and other less common

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2016 Reumatologia

214. Efficacy of an acquainted drug in the treatment of inflammatory low back pain: sulfasalazine under investigation (PubMed)

spondyloarthropathy (USpA) (61.0%) and ankylosing spondylitis (24.6%). During the follow-up period, 3.4% of the participants had an appropriate response to only nonsteroidal anti-inflammatory drugs, 57.6% to sulfasalazine, 26.3% to addition of methotrexate to the previous regimen, and 12.7% to biological agents. Multiple logistic regression results showed that the underlying disease had a significant effect on the sulfasalazine response. The odds for response to treatment was 3.53 times higher in USpA patients (...) compared to other patients (odds ratio =3.53, 95% confidence interval: 1.63-7.68, P=0.001). In 69.4% of the participants, the highest response to sulfasalazine was found, which was related to the underlying USpA. This study found that an adequate response to nonsteroidal anti-inflammatory drugs in patients with ILBP was potentially increased by adding sulfasalazine. Thus, the observed response rate was dependent on the nature of underlying spondyloarthropathy.

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2016 Drug design, development and therapy

215. Profile of adalimumab and its potential in the treatment of uveitis (PubMed)

in treating refractory uveitis in multiple settings, including idiopathic disease, juvenile idiopathic arthritis, sarcoidosis, Behçets disease, and uveitis secondary to spondyloarthropathies, among several other noninfectious uveitis conditions. In this paper, we will review the profile of adalimumab, the role of TNF-α in uveitis, discuss safety data, and summarize key articles evaluating the efficacy of adalimumab in treating uveitis secondary to the most commonly associated autoimmune diseases.

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2016 Drug design, development and therapy

216. Reliability and Factorial Validity of the Turkish Version of the Pain Disability Index in Rheumatic Patients With Chronic Pain (PubMed)

), with most common diagnoses including rheumatoid arthritis, seronegative spondyloarthropathies, and familial Mediterranean fever. Exploratory and confirmatory factor analyses were used for validation and Cronbach's alpha coefficient was determined as the internal reliability of the PDI. Correlations between each item and item-total score were also calculated.The Turkish form of the PDI revealed a two-factor model. Cronbach's alpha for the total scale was found as 0.86. All items were correlated

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2016 Archives of Rheumatology

217. Alteration of Fecal Microbiota Profiles in Juvenile Idiopathic Arthritis. Associations with HLA-B27 Allele and Disease Status (PubMed)

Alteration of Fecal Microbiota Profiles in Juvenile Idiopathic Arthritis. Associations with HLA-B27 Allele and Disease Status Alteration of gut microbiota is involved in several chronic inflammatory and autoimmune diseases, including rheumatoid arthritis, and gut microbial "pro-arthritogenic" profiles have been hypothesized. Intestinal inflammation may be involved in spondyloarthropathies and in a subset of patients affected by Juvenile Idiopathic Arthritis (JIA), the most common chronic

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2016 Frontiers in microbiology

218. PK, PD, Safety, and Efficacy of SAIT101 Versus MabThera® Versus Rituxan® in Patients With Rheumatoid Arthritis

/bed bound. History of or current inflammatory joint disease other than RA (including but not limited to gout, reactive arthritis, psoriatic arthritis, seronegative spondyloarthropathy or Lyme disease). History of or current systemic autoimmune disorder (including but not limited to systemic lupus erythematosus, inflammatory bowel disease, pulmonary fibrosis, Felty syndrome, scleroderma, inflammatory myopathy, fibromyalgia, juvenile idiopathic arthritis, mixed connective tissue disease, vasculitis

2016 Clinical Trials

219. Evaluation of the Evolution of Imaging Markers of Cartilage Degradation in Patients With Knee Osteoarthritis Receiving DROGLICAN

interfering with the evaluation of OA and/or pain such as articular dysplasia, aseptic osteonecrosis, acromegaly, Paget's disease, hemophilia, hemochromatosis, chondromatosis, villonodular synovitis of the knee, seronegative spondyloarthropathy, rheumatoid arthritis, gouty arthritis , infectious arthritis, radiculalgia in the lower limbs, arteritis, etc. Radiological K&L grade I or IV Prosthesis in the target knee Related to treatments Analgesics to manage OA knee pain 24h before inclusion visit

2016 Clinical Trials

220. Ultrasound as Imaging Biomarker of Early Response to Tocilizumab and Methotrexate in Very Early Rheumatoid Arthritis

, leflunomide, sulphasalazine) and naïve to any biologics or biosimilars. Exclusion Criteria: History of other concomitant autoimmune disease such as lupus or psoriatic arthritis Meeting diagnostic criteria for any other rheumatic disease than RA (e.g. gout, Lyme disease, seronegative spondyloarthropathy including reactive arthritis, psoriatic arthritis, arthropathy or inflammatory bowel disease) Any previous treatment with : Biologics: Etanercept, infliximab, certolizumab, golimumab, abatacept, adalimumab

2016 Clinical Trials

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