How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

995 results for

Spondyloarthropathy

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

181. Serologic Evidence of Gut-driven Systemic Inflammation in Juvenile Idiopathic Arthritis. Full Text available with Trip Pro

Serologic Evidence of Gut-driven Systemic Inflammation in Juvenile Idiopathic Arthritis. Accumulating evidence links juvenile idiopathic arthritis (JIA) to nonhost factors such as gut microbes. We hypothesize that children with new-onset JIA have increased intestinal bacterial translocation and circulating lipopolysaccharide (LPS).We studied systemic treatment-naive patients with JIA [polyarticular JIA, n = 22, oligoarticular JIA, n = 31, and spondyloarthropathies (SpA), n = 16], patients

2017 Journal of Rheumatology

182. A Randomised, Double-blind, Phase I/II Study to Evaluate the PK, PD, Safety, and Efficacy Between HLX01 and Rituximab in Patients With Moderate to Severe Rheumatoid Arthritis and Inadequate Response to Treatment With DMARDs

, in the opinion of the investigator Pregnant or lactating female subjects, or subjects who are planning to conceive or breastfeed during the study period or within 12 months after the last administration. History of, or current, inflammatory joint disease other than RA (e.g., gout, reactive arthritis, psoriatic arthritis, seronegative spondyloarthropathy, Lyme disease) or other systemic autoimmune disorder (e.g., systemic lupus erythematosus, inflammatory bowel disease, pulmonary fibrosis, or Felty's syndrome

2017 Clinical Trials

183. What is hidradenitis suppurativa? Full Text available with Trip Pro

based on typical lesions (nodules, abscesses, sinus tracts), locations (skin folds), and nature of relapses and chronicity. Multiple comorbidities are associated with HS, including obesity, metabolic syndrome, inflammatory bowel disease, and spondyloarthropathy. Although the lack of curative therapy and the recurrent nature makes HS treatment challenging, there are effective symptomatic management options.Family physicians should be suspicious of HS in patients presenting with recurrent skin

2017 Canadian Family Physician

184. Juvenile Idiopathic Arthritis Full Text available with Trip Pro

subtype, characterized by enthesitis and asymmetric lower-extremity arthritis. This disease subtype represents the childhood form of adult spondyloarthropathies, with human leukocyte antigen-B27 positivity and uveitis but commonly without axial skeleton involvement. Juvenile psoriatic arthritis is characterized by a psoriatic rash, accompanied by arthritis, nail pitting and dactylitis. Disease complications can vary from growth retardation and osteoporosis secondary to treatment and disease activity

2017 Balkan medical journal

185. Managing morbidity and treatment-related toxicity in patients with ankylosing spondylitis Full Text available with Trip Pro

Managing morbidity and treatment-related toxicity in patients with ankylosing spondylitis AS is the prototypical member of the family of spondyloarthropathies, and is characterized by seronegativity, axial predominance and new bone formation, which underlie symptoms of inflammatory back pain, enthesopathy and extra-articular manifestations, including anterior uveitis, psoriasis and colitis. Patients with AS typically experience a wide variety of morbidities. These include both morbidities

2017 Rheumatology (Oxford, England)

186. Cardiovascular magnetic resonance imaging: clinical implications in the evaluation of connective tissue diseases Full Text available with Trip Pro

. Rheumatoid arthritis and other spondyloarthropathies, systemic lupus erythematosus, inflammatory myopathies, mixed connective tissue diseases (CTDs), systemic sclerosis, vasculitis, and sarcoidosis are among CTDs with serious cardiovascular involvement; this is due to multiple causative factors such as myopericarditis, micro/macrovascular disease, coronary artery disease, myocardial fibrosis, pulmonary hypertension, and finally heart failure. The complicated pathophysiology and the high cardiovascular

2017 Journal of inflammation research

187. The performance of different classification criteria sets for spondyloarthritis in the worldwide ASAS-COMOSPA study Full Text available with Trip Pro

with SpA by rheumatologists worldwide. Patients were classified according to the European Spondyloarthropathy Study Group (ESSG), modified European Spondyloarthropathy Study Group (mESSG), Amor, modified Amor, Assessment of SpondyloArthritis international Society (ASAS) axial Spondyloarthritis (axSpA), ASAS peripheral spondyloarthritis (pSpA) and ClASsification criteria for Psoriatic Arthritis (CASPAR) criteria. Overlap between the classification criteria sets was assessed for patients with and without

2017 Arthritis research & therapy

188. Imaging of juvenile spondyloarthritis. Part I: Classifications and radiographs Full Text available with Trip Pro

Imaging of juvenile spondyloarthritis. Part I: Classifications and radiographs Juvenile spondyloarthropathies are manifested mainly by symptoms of peripheral arthritis and enthesitis. By contrast with adults, children rarely present with sacroiliitis and spondylitis. Imaging and laboratory tests allow early diagnosis and treatment. Conventional radiographs visualize late inflammatory lesions and post-inflammatory complications. Early diagnosis is possible with the use of ultrasonography (...) and magnetic resonance imaging. The first part of the article presents classifications of juvenile spondyloarthropathies and discusses their radiographic presentation. Typical radiographic features of individual types of juvenile spondyloarthritis are listed (including ankylosing spondylitis, juvenile psoriatic arthritis, reactive arthritis and arthritis in the course of inflammatory bowel diseases). The second part will describe changes visible on ultrasonography and magnetic resonance imaging

2017 Journal of Ultrasonography

189. Imaging of juvenile spondyloarthritis. Part II: Ultrasonography and magnetic resonance imaging Full Text available with Trip Pro

Imaging of juvenile spondyloarthritis. Part II: Ultrasonography and magnetic resonance imaging Juvenile spondyloarthropathies are mainly manifested by symptoms of peripheral arthritis and enthesitis. Early involvement of sacroiliac joints and spine is exceptionally rare in children; this usually happens in adulthood. Conventional radiographs visualize late inflammatory lesions. Early diagnosis is possible with the use of ultrasonography and magnetic resonance imaging. The first part (...) of the article presented classifications and radiographic presentation of juvenile spondyloarthropathies. This part discusses changes seen on ultrasonography and magnetic resonance imaging. In patients with juvenile spondyloarthropathies, these examinations are conducted to diagnose inflammatory lesions in peripheral joints, tendon sheaths, tendons and bursae. Moreover, magnetic resonance also shows subchondral bone marrow edema, which is considered an early sign of inflammation. Ultrasonography and magnetic

2017 Journal of Ultrasonography

190. Insight on Bone Morphogenetic Protein 7 in Ankylosing Spondylitis and its association with disease activity and radiographic damage Full Text available with Trip Pro

Insight on Bone Morphogenetic Protein 7 in Ankylosing Spondylitis and its association with disease activity and radiographic damage Fusion of joints as well as intervertebral spaces by the formation of bony spurs appearing as syndesmophytes and osteophytes are the hallmark of spondyloarthropathies which accounts for disability. The aim of this study was to assess the serum level of bone morphogenetic protein (BMP)-7 in ankylosing spondylitis and its relationship with disease activity (...) and the radiographic damage.This longitudinal case control study was conducted in Ain Shams University Hospitals (Egypt). A total of 55 subjects were included in two case groups and one control group. Group I included 20 patients with Ankylosing Spondylitis (AS) assessed at baseline (defined as Ia and after 18 months defined as Ib). Group II included 20 patients with Rheumatoid Arthritis (RA) and Group III included 15 healthy subjects as controls. Patients with other forms of seronegative spondyloarthropathies

2016 Electronic physician

191. Mitigation of disease- and treatment-related risks in patients with psoriatic arthritis Full Text available with Trip Pro

Mitigation of disease- and treatment-related risks in patients with psoriatic arthritis Psoriatic arthritis is a part of the family of diseases referred to as spondyloarthropathies, a diverse group of chronic inflammatory disorders with common clinical, radiographic, and genetic features. Peripheral arthritis is the most common symptom of psoriatic arthritis and patients also frequently experience involvement of the entheses, spine, skin, and nails. Due to the diverse clinical spectrum

2017 Arthritis research & therapy

192. Animal models of rheumatoid pain: experimental systems and insights Full Text available with Trip Pro

Animal models of rheumatoid pain: experimental systems and insights Severe chronic pain is one of the hallmarks and most debilitating manifestations of inflammatory arthritis. It represents a significant problem in the clinical management of patients with common chronic inflammatory joint conditions such as rheumatoid arthritis, psoriatic arthritis and spondyloarthropathies. The functional links between peripheral inflammatory signals and the establishment of the neuroadaptive mechanisms acting

2017 Arthritis research & therapy

193. Description of Spondylarthritis and Validation of ASAS Criteria in West Indian Patients Seen in Consultation of Rheumatology.

of spondyloarthropathies to allow for early diagnosis, Nuclear magnetic resonance imaging (MRI). This approach led to the publication in 2009 of the classification criteria for spondylarthritis, in particular axial spondyloarthritis, as well as a proposal to modify the classification of criteria defined by Mr. Amor (AMOR) and European Spondylarthropathy Study Group (ESSG) criteria, taking into account the potential abnormalities visible in Magnetic Resonance Imaging Nuclear (MRI). The performance (specificity

2017 Clinical Trials

194. Cartography and Quantitative Characterization of Achilles Tendon Fibrocartilage by TE = 0ms Imaging at 3T MRI

enthesis study using the calcaneal tendon as a clinical model Condition or disease Intervention/treatment Phase Spondyloarthropathy Tendinopathy Device: MRI ZTE2 sequence Not Applicable Detailed Description: The human body contains a lot of tissue components with short T2 (transversal relaxation time) that are not or only poorly detected on conventional T2-weighted MR sequences. These components are mostly located in musculoskeletal organs such as tendons, ligaments, menisci, periosteum or cortical (...) bone. Considering that conventional sequences do not detect tissue components with T2 shorter than 10ms, imaging of body tendon or enthesis is therefore very limited. This represents a limitation of MR imaging in early diagnosis of a certain number of pathologies, such as mechanical or mostly inflammatory tendinopathy or enthesopathy. This study, would provide the feasibility of ZTE 2 sequence to quantitatively assess normal and pathological spondyloarthropathy Achilles tendon enthesis at 3 T

2017 Clinical Trials

195. Safety, Tolerability, PK and PD of Biosimilar Drug Ritumax® Compared to Original Drug MabThera®

be stable within the last 4 weeks prior to screening Exclusion Criteria: The patient will be deemed ineligible for the study meeting any of the following criteria: Other inflammatory arthropathies apart from rheumatoid arthritis (e.g. gout, reactive arthritis, psoriatic arthritis, seronegative spondyloarthropathy, Lyme desease) or other system autoimmune diseases (e.g. systemic lupus erythematosus, inflammatory bowel disease, pneumosclerosis or Felly's syndrome, sclerodermia, inflammatory myopathy

2017 Clinical Trials

196. The SpACE Study

The SpACE Study The SpACE Study - Small Bowel Crohn's Disease and Spondyloarthropathies - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. The SpACE Study - Small Bowel Crohn's Disease (...) and Spondyloarthropathies (SpACE) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03064815 Recruitment Status : Completed First Posted : February 27, 2017 Last Update Posted : March 1, 2017 Sponsor: McGill University Health Center Collaborators: AbbVie Prometheus Laboratories Information provided by (Responsible Party

2017 Clinical Trials

197. A Study of Infuse® Bone Graft With Mastergraft® Strip and Posterior Fixation for Posterolateral Fusion (PLF) Treatment of Multi-Level Degenerative Lumbosacral Spinal Conditions

or prior history of malignancy. Overt or active bacterial infection, either local or systemic. Has undergone systemic administration of any type of corticosteroid, anti-neoplastic, immunostimulating, or immunosuppressive agents within 30 days prior to implantation of the assigned treatment. Comorbidities precluding subject from being a surgical candidate. History of autoimmune disease known to affect bone metabolism or the spine (e.g., spondyloarthropathies, juvenile arthritis, rheumatoid arthritis

2017 Clinical Trials

198. Dietary Supplement for Joint: the OLE Study

synovitis of the knee, seronegative spondyloarthropathy, rheumatoid arthritis, gouty arthritis , infectious arthritis, radiculalgia in the lower limbs, arteritis Prosthesis in the target knee Diagnosed arthrosis eligible to knee/joint surgery/replacement Related to treatments Analgesics to manage knee pain 24h before inclusion visit Corticosteroids injection in the target knee in the month preceding inclusion Hyaluronan injection in the target knee in the last 6 months Oral corticotherapy ≥ 5mg/day

2017 Clinical Trials

199. Evaluation of Platelet Rich Plasma (PRP) for Knee Osteoarthritis

medication in any other joint less than 1 month after inclusion; Introduction of any medical or physiotherapeutic intervention in the last 3 months (rehabilitation, acupuncture, cane, orthotics, etc.) for locomotor system; Body Mass Index (BMI) greater than 35. Presence of other types of arthropathies such as rheumatoid arthritis, diffuse connective tissue diseases, microcrystalline arthropathies, spondyloarthropathies and infectious arthropathies. Symptomatic osteoarthritis of hip and feet Presence

2017 Clinical Trials

200. Chronic Inflammatory Disease, Lifestyle and Treatment Response

(score) Rheumatoid Arthritis: Disease-specific core outcome sets-7 [ Time Frame: week 14-16 ] • C-Reactive protein (mg/l) Rheumatoid Arthritis: Disease-specific core outcome sets-8 [ Time Frame: week 14-16 ] • DAS28-CRP (score) Rheumatoid Arthritis: Disease-specific core outcome sets-9 [ Time Frame: week 14-16 ] • Simplified Disease Activity Index (SDAI) (index) Axial Spondyloarthropathy: Disease-specific core outcome sets-1 [ Time Frame: week 14-16 ] • BASFI (score) Axial Spondyloarthropathy (...) : Disease-specific core outcome sets-2 [ Time Frame: week 14-16 ] • BASDAI (score) Axial Spondyloarthropathy: Disease-specific core outcome sets-3 [ Time Frame: week 14-16 ] • BASMI (score) Axial Spondyloarthropathy: Disease-specific core outcome sets-4 [ Time Frame: week 14-16 ] • Total score for back pain (0-100 mm VAS) Axial Spondyloarthropathy: Disease-specific core outcome sets-5 [ Time Frame: week 14-16 ] • Physician global assessment (0-100 mm VAS) Axial Spondyloarthropathy: Disease-specific core

2017 Clinical Trials

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>