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Spondyloarthropathy due to Inflammatory Bowel Disease

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1. Spondyloarthropathy due to Inflammatory Bowel Disease

Spondyloarthropathy due to Inflammatory Bowel Disease Spondyloarthropathy due to Inflammatory Bowel Disease Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse (...) Cancer Administration 4 Spondyloarthropathy due to Inflammatory Bowel Disease Spondyloarthropathy due to Inflammatory Bowel Disease Aka: Spondyloarthropathy due to Inflammatory Bowel Disease , Crohn's Disease Associated Arthritis , Ulcerative Colitis Associated Arthritis , Colitic Arthritis , Arthritis associated with Ulcerative Colitis , Inflammatory Bowel Disease with Spondyloarthropathy , Arthropathy of Inflammatory Bowel Disease , Enteropathic Arthritis II. Pathophysiology Associated with Greater

2018 FP Notebook

2. Spondyloarthropathy due to Inflammatory Bowel Disease

Spondyloarthropathy due to Inflammatory Bowel Disease Spondyloarthropathy due to Inflammatory Bowel Disease Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse (...) Cancer Administration 4 Spondyloarthropathy due to Inflammatory Bowel Disease Spondyloarthropathy due to Inflammatory Bowel Disease Aka: Spondyloarthropathy due to Inflammatory Bowel Disease , Crohn's Disease Associated Arthritis , Ulcerative Colitis Associated Arthritis , Colitic Arthritis , Arthritis associated with Ulcerative Colitis , Inflammatory Bowel Disease with Spondyloarthropathy , Arthropathy of Inflammatory Bowel Disease , Enteropathic Arthritis II. Pathophysiology Associated with Greater

2015 FP Notebook

3. Skeletal Health of Children and Adolescents With Inflammatory Bowel Disease

Skeletal Health of Children and Adolescents With Inflammatory Bowel Disease Copyright 2011 by ESPGHAN and NASPGHAN. Unauthorized reproduction of this article is prohibited. Skeletal Health of Children and Adolescents With Inflammatory Bowel Disease Helen Pappa, y Meena Thayu, z Francisco Sylvester, § Mary Leonard, y Babette Zemel, and jj Catherine Gordon ABSTRACT Current evidence points to suboptimal bone health in children and adoles- cents with in?ammatory bowel disease (IBD) when compared (...) of the effect of biologics on bone health in children and adolescents with IBD, as well as the role of bone active medications such as bisphosphonates. Finally, we summarize the existing numerous gaps in knowledge and potential subjects for future research endeavors. Key Words: adolescents, children, clinical report, in?ammatory bowel disease, skeletal health (JPGN 2011;53: 11–25) PARTA. SCREENING AND MONITORING BONE HEALTH IN CHILDREN AND ADOLESCENTS WITH INFLAMMATORY BOWEL DISEASE (IBD) INTRODUCTION

2011 North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition

4. The British Society for Rheumatology biologic DMARD safety guidelines in inflammatory arthritis

biologic DMARD safety guidelines in inflammatory arthritis, Rheumatology , Volume 58, Issue 2, February 2019, Pages e3–e42, Download citation file: © 2019 Oxford University Press Navbar Search Filter Mobile Microsite Search Term Close search filter search input , , , , , , Introduction The use of biologic therapies has transformed the management of inflammatory arthritis (IA). In contrast to conventional systemic DMARDs (csDMARDs) traditionally used to treat inflammatory disease, these agents offer (...) Mycobacterium MTB TB HIV infection HIV infect* AIDS Kaposi sarcoma Retroviral positive Hepatitis Hepatitis Viral infection Varicella Herpes EBV CMV HPV Cytomegalovirus Epstein Barr Virus HSV VZV Varicella Zoster Fungal infection Fung* Histoplasmos* Aspergillus Coccidiomycosis Malignancy Malignancy Pre-malignant Cancer Lymphoma Lung cancer Bowel cancer Non-melanoma skin cancer Tumour Tumor Carcinoma in situ OR CIS Cervical* OR CIN Barrett* Heart failure Heart failure Cardiac failure Ischaemic heart disease

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2018 British Society for Rheumatology

5. Chronic Extremity Joint Pain?Suspected Inflammatory Arthritis

seronegative spondyloarthropathy. Imaging assessment for the seronegative spondyloarthropathies, which include psoriatic arthritis, reactive arthritis, ankylosing spondylitis, and arthritis associated with inflammatory bowel disease, includes the synovial spaces, entheses, and osseous surfaces of the extremities. Radiography The findings of spondyloarthropathy related to erosions, enthesitis, and bone proliferation are well characterized by radiography [29,30]. Ultrasound US can identify synovial (...) that can indicate the presence of a chronic inflammatory arthritis. Overview of Imaging Modalities Osseous abnormalities In addition to joint space narrowing, the osseous abnormalities of the extremities that are assessed include erosions and bone proliferation. Erosions, which appear as cortical discontinuity, may be seen at the margins of synovial joints (rheumatoid arthritis and spondyloarthropathies), periarticular (gout), central (erosive osteoarthritis), and at the enthesis (spondyloarthropathies

2016 American College of Radiology

6. Ankylosing Spondylitis and Undifferentiated Spondyloarthropathy (Follow-up)

In adults with active AS despite treatment with NSAIDs and who have contraindications to TNFi, conditionally recommend treatment with a SAARD over treatment with a non-TNFi biologic agent In adults with AS and inflammatory bowel disease : No recommendation for any particular NSAID as the preferred choice to decrease the risk of worsening of inflammatory bowel disease symptoms Treatment with TNFi monoclonal antibodies strongly recommended over treatment with etanercept Other recommendations: In adults (...) in ankylosing spondylitis. Nature . 1973 Mar 9. 242(5393):121. . Alvarez I, López de Castro JA. HLA-B27 and immunogenetics of spondyloarthropathies. Curr Opin Rheumatol . 2000 Jul. 12(4):248-53. . McGonagle D, Gibbon W, Emery P. Classification of inflammatory arthritis by enthesitis. Lancet . 1998 Oct 3. 352(9134):1137-40. . Muñoz-Villanueva MC, Muñoz-Gomariz E, Escudero-Contreras A, et al. Biological and clinical markers of disease activity in ankylosing spondylitis. J Rheumatol . 2003 Dec. 30(12):2729-32

2014 eMedicine.com

7. Ankylosing Spondylitis and Undifferentiated Spondyloarthropathy (Overview)

% of patients with AS. Increased levels of fatigue are associated with increased pain and stiffness and decreased functional capacity. [ , ] Extra-articular manifestations of AS can include the following: Uveitis Cardiovascular disease Pulmonary disease Renal disease Neurologic disease Gastrointestinal (GI) disease Metabolic bone disease Undifferentiated spondyloarthropathy Clinical manifestations of undifferentiated spondyloarthropathy include the following: Inflammatory back pain - 90% Buttock pain - 80 (...) by combining clinical criteria of inflammatory back pain and enthesitis or arthritis with radiological findings. Early diagnosis is important because early medical and physical therapy may improve functional outcome. As with any chronic disease, patient education is vital to familiarize the patient with the symptoms, course, and treatment of the disease. Treatment measures include pharmacologic, physical therapy, and surgical. Previous Next: Pathophysiology The spondyloarthropathies are chronic

2014 eMedicine.com

8. Ankylosing Spondylitis and Undifferentiated Spondyloarthropathy (Diagnosis)

% of patients with AS. Increased levels of fatigue are associated with increased pain and stiffness and decreased functional capacity. [ , ] Extra-articular manifestations of AS can include the following: Uveitis Cardiovascular disease Pulmonary disease Renal disease Neurologic disease Gastrointestinal (GI) disease Metabolic bone disease Undifferentiated spondyloarthropathy Clinical manifestations of undifferentiated spondyloarthropathy include the following: Inflammatory back pain - 90% Buttock pain - 80 (...) by combining clinical criteria of inflammatory back pain and enthesitis or arthritis with radiological findings. Early diagnosis is important because early medical and physical therapy may improve functional outcome. As with any chronic disease, patient education is vital to familiarize the patient with the symptoms, course, and treatment of the disease. Treatment measures include pharmacologic, physical therapy, and surgical. Previous Next: Pathophysiology The spondyloarthropathies are chronic

2014 eMedicine.com

9. Ankylosing Spondylitis and Undifferentiated Spondyloarthropathy (Treatment)

In adults with active AS despite treatment with NSAIDs and who have contraindications to TNFi, conditionally recommend treatment with a SAARD over treatment with a non-TNFi biologic agent In adults with AS and inflammatory bowel disease : No recommendation for any particular NSAID as the preferred choice to decrease the risk of worsening of inflammatory bowel disease symptoms Treatment with TNFi monoclonal antibodies strongly recommended over treatment with etanercept Other recommendations: In adults (...) in ankylosing spondylitis. Nature . 1973 Mar 9. 242(5393):121. . Alvarez I, López de Castro JA. HLA-B27 and immunogenetics of spondyloarthropathies. Curr Opin Rheumatol . 2000 Jul. 12(4):248-53. . McGonagle D, Gibbon W, Emery P. Classification of inflammatory arthritis by enthesitis. Lancet . 1998 Oct 3. 352(9134):1137-40. . Muñoz-Villanueva MC, Muñoz-Gomariz E, Escudero-Contreras A, et al. Biological and clinical markers of disease activity in ankylosing spondylitis. J Rheumatol . 2003 Dec. 30(12):2729-32

2014 eMedicine.com

10. Spondyloarthritis in over 16s: diagnosis and management

, enthesitis and dactylitis) or extra-articular (for example, uveitis and psoriasis [including psoriatic nail symptoms]). Risk factors include recent genitourinary infection and a family history of spondyloarthritis or psoriasis. 1.1.3 Be aware that axial and peripheral spondyloarthritis may be missed, even if the onset is associated with established comorbidities (for example, uveitis, psoriasis, inflammatory bowel disease [Crohn's disease or ulcerative colitis], or a gastrointestinal or genitourinary (...) If the person does not meet the criteria in recommendation 1.1.5 but clinical suspicion of axial spondyloarthritis remains, advise the person to seek repeat assessment if new signs, symptoms or risk factors listed in recommendation 1.1.5 develop. This may be especially appropriate if the person has current or past inflammatory bowel disease (Crohn's disease or ulcerative colitis), psoriasis or uveitis (see recommendation 1.1.12 for guidance on referral for immediate [same-day] ophthalmological assessment

2017 National Institute for Health and Clinical Excellence - Clinical Guidelines

11. Assessment of inflamed joint

infections Parvoviral syndrome Lyme disease Juvenile idiopathic arthritis (oligo-articular type) Acute rheumatic fever (ARF) Sarcoidosis Spondyloarthropathy Systemic lupus erythematosus (SLE) Adult-onset Still's disease (AOSD) Reactive arthritis Ankylosing spondylitis (AS) Osteoarthritis Trauma Non-traumatic haemarthrosis Hypertrophic osteoarthropathy Intra-articular metastatic cancer Synovial sarcoma Arbovirus infections (e.g., chikungunya) Inflammatory bowel disease (ulcerative colitis and Crohn's (...) % of such patients undergoing remission requiring no pharmacological therapy at follow-up at 1 year. [Figure caption and citation for the preceding image starts]: Acute monoarthritis of the right knee From the collection of Dr Soumya Chatterjee [Citation ends]. Differentiation of joint pain In addition to inflammatory joint diseases, joint pain can also be due to: Joint damage (e.g., osteoarthritis, or trauma leading to a fracture or internal derangement) Referred pain Altered pain threshold (as is seen

2018 BMJ Best Practice

12. Assessment of inflamed joint

infections Parvoviral syndrome Lyme disease Juvenile idiopathic arthritis (oligo-articular type) Acute rheumatic fever (ARF) Sarcoidosis Spondyloarthropathy Systemic lupus erythematosus (SLE) Adult-onset Still's disease (AOSD) Reactive arthritis Ankylosing spondylitis (AS) Osteoarthritis Trauma Non-traumatic haemarthrosis Hypertrophic osteoarthropathy Intra-articular metastatic cancer Synovial sarcoma Arbovirus infections (e.g., chikungunya) Inflammatory bowel disease (ulcerative colitis and Crohn's (...) % of such patients undergoing remission requiring no pharmacological therapy at follow-up at 1 year. [Figure caption and citation for the preceding image starts]: Acute monoarthritis of the right knee From the collection of Dr Soumya Chatterjee [Citation ends]. Differentiation of joint pain In addition to inflammatory joint diseases, joint pain can also be due to: Joint damage (e.g., osteoarthritis, or trauma leading to a fracture or internal derangement) Referred pain Altered pain threshold (as is seen

2018 BMJ Best Practice

13. Spine imaging

to epidural abscess, arachnoiditis, discitis, and osteomyelitis. IMAGING STUDY - CT or MRI all spinal levels - FDG-PET for chronic osteomyelitis Spondyloarthropathy Includes ankylosing spondylitis, reactive arthritis, psoriatic arthritis, spondyloarthropathy associated with inflammatory bowel disease, and juvenile-onset spondyloarthritis Advanced imaging of the spine is considered medically necessary for diagnosis following standard evaluation with radiographs and/or laboratory evaluation. IMAGING STUDY (...) Infectious and Inflammatory Conditions 12 Juvenile idiopathic arthritis (Pediatric only) 12 Multiple sclerosis or other white matter disease 12 Rheumatoid arthritis (Adult only) 12 Spinal infection 13 Spondyloarthropathy 13 Trauma 14 Cervical injury 14 Thoracic or lumbar injury 14 Tumor 15 Tumor 15 Miscellaneous Conditions of the Spine 15 Osteoporosis and osteopenia 15 Spinal cord infarction 16 Spondylolysis and spondylolisthesis 16 Syringomyelia 16 Signs and Symptoms 16 Cauda equina syndrome 16

2019 AIM Specialty Health

14. Appropriate Use Criteria: Imaging of the Abdomen and Pelvis

Tumor or neoplasm – not otherwise referenced 12 Female Reproductive System and Obstetrics 12 Adenomyosis 12 Adnexal mass 12 Endometriosis 13 Obstetric indications 13 Uterine artery embolization procedures 13 Gastrointestinal Conditions 14 Appendicitis 14 Bowel obstruction 14 Constipation (Pediatric only) 15 Diverticulitis 15 Enteritis and colitis 15 Foreign body (Pediatric only) 16 Gastrointestinal bleeding (Pediatric only) 16 Henoch-Schonlein purpura (Pediatric only) 16 Inflammatory bowel disease (...) 16 Intussusception (Pediatric only) 16 Ischemic bowel 17 Hepatobiliary Conditions 17 Ascites 17 Biliary tract dilatation or obstruction 17 Cholecystitis 17 Imaging of the Abdomen and Pelvis Copyright © 2019. AIM Specialty Health. All Rights Reserved. 3 Choledocholithiasis 18 Diffuse liver disease 18 Focal liver lesion 19 Hepatomegaly 20 Jaundice 20 Primary sclerosing cholangitis 21 Osseous Conditions 21 Avascular necrosis 21 Axial spondyloarthropathy 21 Developmental hip dysplasia (Pediatric only

2019 AIM Specialty Health

15. AGA Clinical Practice Guidelines on the Management of Mild-to-Moderate Ulcerative Colitis

, University of Washington, Seattle, Washington 1 , x Siddharth Singh Affiliations Division of Gastroenterology, University of California, San Diego, La Jolla, California 2 , x Joseph D. Feuerstein Affiliations Division of Gastroenterology and Center for Inflammatory Bowel Diseases, Beth Israel Deaconess Medical Center, Boston, Massachusetts 3 , x Corinna Falck-Ytter Affiliations Division of Internal Medicine, Louis Stokes Veterans Affairs Medical Center, Case Western Reserve University, Cleveland, Ohio 4 (...) Association technical review on the management of mild-moderate ulcerative colitis. Gastroenterology . 2018 ; | | | that is a compilation of the clinical evidence on which these recommendations were formulated. Development of this guideline and the accompanying technical review was fully funded by the AGA Institute without additional outside funding. UC is a chronic inflammatory bowel disease with onset most frequently in young adulthood. Most patients with UC have a mild-to-moderate course characterized

2019 American Gastroenterological Association Institute

16. American College of Rheumatology/Arthritis Foundation Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Non-Systemic Polyarthritis, Sacroiliitis, and Enthesitis

arthritis or sacroiliitis. These guidelines are not intended to be applicable to children with associated extraarticular manifes- tations (e.g., psoriasis, uveitis, inflammatory bowel disease) that may also influence treatment decisions. Given the heterogeneity of patients with JIA and polyarthritis, the Expert and Voting Panels initially categorized patients into treatment groups, using combi- nations of the following categories: 1) presence or absence of risk factors for disease severity (...) –27). A joint with inactive disease was defined using the ACR definition: presence of swelling (not due to currently inactive synovitis or to bony enlargement) or, if swell- ing is not present, limitation of motion accompanied by pain, tenderness, or both (28,29). The Voting Panel used the clinical JADAS based on 10 joints (cJADAS- 10) and a cutoff of =2.5 versus >2.5 to define low versus high/moderate disease activ- ity. Low disease activity was further defined as a cJADAS- 10 of =2.5 and =1

2019 American College of Rheumatology

17. Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis

, stiffness, and limited flexibility varies widely among patients and over the course of axial SpA. Skeletal disease may be accompanied by uveitis, psoriasis, and inflammatory bowel disease (IBD). Axial SpA can impose substantial physical and social burdens on patients, and can interfere with work and schooling (5,6). The goals of treat- ment are to alleviate symptoms, improve functioning, maintain the ability to work, decrease disease complications, and forestall skeletal damage as much as possible (...) conditionally recommend prescription of topical glucocorticoids over no prescription for prompt at-home use in the event of eye symptoms to decrease the severity or duration of iritis episodes.† Very low 28 39. In adults with recurrent iritis, we conditionally recommend treatment with TNFi monoclonal antibodies over treat- ment with other biologics. Low 29 40. In adults with inflammatory bowel disease, we do not recommend any particular NSAID as the preferred choice to decrease the risk of worsening

2019 American College of Rheumatology

18. Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with awareness and attention to comorbidities

for reports published during January 1, 1980-December 31, 2017, capable of addressing all of the newly identified clinical questions ( Table I ). Searches were limited to publications in the English language. Medical subject heading terms used in various combinations in the literature search included “psoriasis,” “inflammatory bowel disease,” “Crohn's disease,” “ulcerative colitis,” “metabolic syndrome,” “diabetes,” “obesity,” “dyslipidemia,” “hypertension,” “nonalcoholic fatty liver disease (...) Clinical questions What are the available screening and/or therapeutic interventions in managing the following comorbidities in adults: i. Psoriatic arthritis ii. Cardiovascular disease iii. Metabolic syndrome iv. Mental health v. Lifestyle choices vi. Inflammatory bowel disease vii. Malignancy viii. Renal disease ix. Sleep apnea x. Chronic obstructive pulmonary disease xi. Uveitis xii. Hepatic disease For a full description of the methodology used herein, please refer to the Appendix . Definition

2019 American Academy of Dermatology

19. Familial Mediterranean fever

Familial Mediterranean fever Familial Mediterranean fever - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Familial Mediterranean fever Last reviewed: February 2019 Last updated: September 2017 Summary Primarily a genetic disease due to Mendelian-recessive inheritance of Mediterranean fever gene mutations. Occurs mainly in people of Mediterranean ancestry, especially from Arabian countries, Turkey, Israel, and Armenia (...) and prevents the most serious and life-threatening complication, renal amyloidosis. Definition Familial Mediterranean fever (FMF; phenotype Mendelian Inheritance in Man number 249100) is part of the currently expanding family of auto-inflammatory disorders.The disease originated over 2000 years ago in western Asia and spread to the Mediterranean basin and the rest of the globe with the advent of extensive global migration. First classified as a clinical disease by Siegal in 1949, Siegal S. Benign

2017 BMJ Best Practice

20. Level of Care for Musculoskeletal Surgery

-and-Notices-Items/CMS- 1678-FC.html?DLPage=1&DLEntries=10&DLSort=2&DLSortDir=descending Copyright © 2018. AIM Specialty Health. All Rights Reserved. Level of Care for Musculoskeletal Surgery and Procedures 8 • Indications that are emergent and/or systemic o Acute trauma with fracture o Spinal neoplasm o Septic arthritis o Complication of inflammatory arthritis / seronegative spondyloarthropathy (SpA) • Prolonged operative or anesthesia time (anticipated > 3 hours) • Revision surgery • Procedure specific o (...) /Hospital-Outpatient-Regulations-and-Notices-Items/CMS- 1678-FC.html?DLPage=1&DLEntries=10&DLSort=2&DLSortDir=descending • Indications that are emergent and/or systemic o Acute trauma with fracture o Spinal neoplasm o Septic arthritis o Complication of inflammatory arthritis / seronegative spondyloarthropathy (SpA) • Prolonged operative or anesthesia time (> 3 hours) • Revision surgery • Surgical facility does not have capability for 23-hour observation or arrangements in place for overnight hospital

2018 AIM Specialty Health

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