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Splenic Injury

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61. Traumatic Splenic Injury and Management (SPLENIQ Study)

: literature search and conducting the retrospective study and analyses. Years 1-3: inclusion prospective study and follow-up of patients. Year 4: finishing follow-up data collection and analysing. Condition or disease Intervention/treatment Quality of Life Spleen Injury Trauma Splenic Artery Embolization Other: Questionnaires Diagnostic Test: MRI abdomen Study Design Go to Layout table for study information Study Type : Observational Actual Enrollment : 106 participants Observational Model: Cohort Time (...) Perspective: Prospective Official Title: Traumatic Splenic Injury and Management (SPLENIQ Study) Quality of Life and Clinical Outcomes of Treatment for Splenic Injury After Trauma Actual Study Start Date : March 1, 2017 Estimated Primary Completion Date : December 31, 2019 Estimated Study Completion Date : December 31, 2019 Groups and Cohorts Go to Group/Cohort Intervention/treatment Non-Operative Management (NOM)/Observational Patients "treated" observationally for (traumatic) spleen injury. Other

2017 Clinical Trials

62. Robotic spleen-preserving splenic hilar lymph node dissection during total gastrectomy for gastric cancer. (Abstract)

, the number of harvested LNs in total and at the splenic hilum, and 5-year overall survival were analyzed, retrospectively.Among the 92 patients, robotic spleen-preserving splenic hilar lymphadenectomy was successfully performed in 91 patients except one who experienced intraoperative splenic artery injury which demanded splenectomy to be performed simultaneously. The overall mean operation time and console time were 287.2 ± 66.0 and 180.2 ± 47.2 min, respectively. Mean estimated blood loss was 141.1 (...) Robotic spleen-preserving splenic hilar lymph node dissection during total gastrectomy for gastric cancer. Robotic system may have potential advantages to facilitate the technically challenging splenic hilar lymphadenectomy during gastrectomy for gastric cancer. However, robotic spleen-preserving splenic hilar lymphadenectomy is performed infrequently not only because of the limited availability of the robot but also because of its technical difficulty. In this study, we describe our technique

2019 Surgical endoscopy

63. Splenic Injury

, Injury of Spleen , Ruptured Spleen , Splenic Rupture From Related Chapters II. Grading: AAST CT Grade for Splenic Injury Precautions May not accurately correlate with surgical findings Does not consistently predict the need for surgical intervention Grade 1 Subcapsular hematoma <10% surface area OR Splenic <1 cm depth into parenchyma Grade 2 Subcapsular hematoma 10-50% surface area OR Splenic 1-3 cm depth into parenchyma (not involving trabecular vessels) Grade 3 Subcapsular hematoma >50% surface (...) 210196007 , 157342001 , 269157005 , 23589004 English Injury to spleen , Injury to spleen NOS , injury of spleen , injury of spleen (diagnosis) , Splenic injury , Unspecified injury of spleen , Injury of spleen, unspecified , injury splenic , injury to spleen , Injury;spleen , injury spleen , injuries splenic , splenic injury , injuries spleen , spleen injury , Injury to spleen NOS (disorder) , Injury of spleen , Injury of spleen (disorder) , injury; spleen , spleen; injury , Injury of spleen, NOS

2018 FP Notebook

64. Interventional radiology versus surgical management on mortality for splenic injuries: a systematic review and meta-analysis

Interventional radiology versus surgical management on mortality for splenic injuries: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne

2018 PROSPERO

65. Unusual Complications From Babesia Infection: Splenic Infarction and Splenic Rupture in Two Separate Patients. (Abstract)

in patients with splenic injuries and without obvious traditional risk factors.Copyright © 2018 Elsevier Inc. All rights reserved. (...) Unusual Complications From Babesia Infection: Splenic Infarction and Splenic Rupture in Two Separate Patients. Babesiosis is a zoonotic parasitic infection transmitted by the tick, Ixodes scapularis. Splenic infarct and rupture are infrequent complications of Babesia parasitemia, and have not been previously reported in the emergency medicine literature.We present two separate cases seen within 1 month at our institution: a case of splenic rupture and another case of splenic infarction due

2018 Journal of Emergency Medicine

66. How Does the Severity of Injury Vary between Motorcycle and Automobile Accident Victims Who Sustain High-Grade Blunt Hepatic and/or Splenic Injuries? Results of a Retrospective Analysis Full Text available with Trip Pro

How Does the Severity of Injury Vary between Motorcycle and Automobile Accident Victims Who Sustain High-Grade Blunt Hepatic and/or Splenic Injuries? Results of a Retrospective Analysis High-grade blunt hepatic and/or splenic injuries (BHSI) remain a great challenge for trauma surgeons. The main aim of this study was to investigate the characteristics, mortality rates, and outcomes of high-grade BHSI in motorcyclists and car occupants hospitalized for treatment of traumatic injuries in a Level (...) I trauma center in southern Taiwan.High-grade BHSI are defined as grade III-VI blunt hepatic injuries and grade III-V blunt splenic injuries. This retrospective study reviewed the data of 101 motorcyclists and 32 car occupants who experienced a high-grade BHSI from 1 January 2011 to 31 December 2013. Two-sided Fisher's exact or Pearson's chi-square tests were used to compare categorical data, unpaired Student's t-test was used to analyze normally distributed continuous data, and Mann-Whitney's U

2016 International journal of environmental research and public health

67. Blunt splenic injury and severe brain injury: a decision analysis and implications for care Full Text available with Trip Pro

Blunt splenic injury and severe brain injury: a decision analysis and implications for care The initial nonoperative management (NOM) of blunt splenic injuries in hemodynamically stable patients is common. In soldiers who experience blunt splenic injuries with concomitant severe brain injury while on deployment, however, NOM may put the injured soldier at risk for secondary brain injury from prolonged hypotension.We conducted a decision analysis using a Markov process to evaluate 2 strategies (...) for managing hemodynamically stable patients with blunt splenic injuries and severe brain injury--immediate splenectomy and NOM--in the setting of a field hospital with surgical capability but no angiography capabilities. We considered the base case of a 40-year-old man with a life expectancy of 78 years who experienced blunt trauma resulting in a severe traumatic brain injury and an isolated splenic injury with an estimated failure rate of NOM of 19.6%. The primary outcome measured was life expectancy. We

2015 Canadian Journal of Surgery

68. Non-operative management for penetrating splenic trauma: how far can we go to save splenic function? Full Text available with Trip Pro

Non-operative management for penetrating splenic trauma: how far can we go to save splenic function? Selective non-operative management (NOM) for the treatment of blunt splenic trauma is safe. Currently, the feasibility of selective NOM for penetrating splenic injury (PSI) is unclear. Unfortunately, little is known about the success rate of spleen-preserving surgical procedures. The aim of this study was to investigate the outcome of selective NOM for penetrating splenic injuries.A dual-centre (...) study is performed in two level-one trauma centres. All identified patients treated for PSI were identified. Patients were grouped based on the treatment they received. Group one consisted of splenectomised patients, the second group included patients treated by a spleen-preserving surgical intervention, and group three included those patients who were treated by NOM.A total of 118 patients with a median age of 27 and a median ISS of 25 (interquartile range (IQR) 16-34) were included. Ninety-six

2017 World journal of emergency surgery : WJES

69. Predicting the Outcome of Non-operative Management of Splenic Trauma in South Africa. (Abstract)

managed with OP or NOM for splenic trauma were identified and analyzed descriptively. Multiple logistic regression analysis identified patients and clinical factors associated with management type.There were 127 patients with splenic injury. Median age was 29 [19-35] years with 42 (33%) women and 85 (67%) men. Blunt injuries occurred in the majority (81, 64%). Organ Injury Scale (OIS) grades included I (25, 20%), II (43, 34%), III (36, 28%), IV (15, 11%), and V (8, 6%). Nine patients expired (...) ratio, 1.4; 95%CI 1.1-1.9) were significantly associated with OP compared to NOM (p = 0.002; area under the curve 0.81).We have identified injury mechanism and admission lactate as factors predictive of OP in South African patients with splenic trauma. Timely presentation to definitive care affects both ICU duration of stay and mortality outcomes. Future global surgical efforts may focus on expanding non-operative management protocols and improving pre-hospital care in patients with splenic trauma.

2020 World Journal of Surgery

70. The cost to perform splenic artery embolisation following blunt trauma: Analysis from a level 1 Australian trauma centre. (Abstract)

The cost to perform splenic artery embolisation following blunt trauma: Analysis from a level 1 Australian trauma centre. Splenic artery embolisation (SAE) has been shown to be an effective treatment for haemodynamically stable patients with high-grade blunt splenic injury. However, there are no local estimates of how much treatment costs. The purpose of this study was to evaluate the cost of providing SAE to patients in the setting of blunt abdominal trauma at an Australian level 1 trauma (...) centre.This was a single-centre retrospective review of 10 patients who underwent splenic embolisation from December 2017 to December 2018 for the treatment of isolated blunt splenic injury, including cost of procedure and the entire admission. Costs included angiography costs including equipment, machine, staff, and post-procedural costs including pharmacy, general ward costs, orderlies, ward nursing, allied health, and further imaging.During the study period, patients remained an inpatient for a mean

2020 Injury

71. Spontaneous Splenic Rupture Two Weeks After Sleeve Gastrectomy. (Abstract)

Spontaneous Splenic Rupture Two Weeks After Sleeve Gastrectomy. Sleeve gastrectomy is one of the commonest bariatric procedures performed globally with an acceptable rate of reported complications. Splenic injury during this procedure is a rare but can be a serious complication. A 32-year-old male patient who had a spontaneous splenic rupture two weeks after an uneventful sleeve gastrectomy needed an emergency splenectomy. Spontaneous rupture after sleeve gastrectomy is an extremely rare

2020 Obesity Surgery

72. Comparison of the efficacy of five standard topical hemostats: a study in porcine liver and spleen models of surgical bleeding. Full Text available with Trip Pro

and spleen surgical bleeding models.Cutanplast Standard and Fast gelatin sponge and Emosist ORC gauze were tested in liver abrasion/incision, liver puncture and spleen incision/puncture injuries, and Cutanplast Standard and Fast gelatin powder products were tested in liver abrasion/incision injuries. There were 13 liver injury (five abrasion, five incision and three puncture) and six spleen injury (three puncture and three incision sites) sites per animal.Rapid hemostasis (≤ 2-5 min) was achieved (...) Comparison of the efficacy of five standard topical hemostats: a study in porcine liver and spleen models of surgical bleeding. Several topical hemostats are available to help control surgical bleeding. Cutanplast is a highly absorbent and porous gelatin product that is available in Fast sponge and powder forms. This study investigated the hemostatic efficacy of Cutanplast Standard and Fast gelatin sponge and powder and Emosist oxidized regenerated cellulose (ORC) gauze in porcine liver

2020 BMC Surgery

73. A rare case of malignant hypertension with splenic rupture and thrombotic microangiopathy: A case report. Full Text available with Trip Pro

A rare case of malignant hypertension with splenic rupture and thrombotic microangiopathy: A case report. Thrombotic microangiopathy (TMA) is characterized by endothelial injury followed by formation of multiple microthrombi in the target organs due to various causes, including malignant hypertension (MHT). Here, we reported a rare case of MHT with splenic TMA changes.A 27-year-old Chinese Han male with a history of hypertension and proteinuria, admitted to our hospital because of renal failure (...) with MHT and thrombocytopenia.This case diagnosed with TMA based on the patient's MHT and thrombocytopenia. The patient final diagnosis was confirmed by the spleen pathological findings, other differential diagnoses were ruled out.The patient was treated with hemodialysis and intravenous antihypertensive agents, and his condition gradually improved. However, he suddenly complained of abdominal pain and went into hemorrhagic shock, which was due to spontaneous spleen rupture on the third day

2020 Medicine

74. Blunt Splenic Injury: Use of a Multidetector CT-based Splenic Injury Grading System and Clinical Parameters for Triage of Patients at Admission. Full Text available with Trip Pro

Blunt Splenic Injury: Use of a Multidetector CT-based Splenic Injury Grading System and Clinical Parameters for Triage of Patients at Admission. To assess the use of a dual-phase multidetector computed tomography (CT)-based grading system alone and in combination with assessment of clinical parameters at triage of patients with blunt splenic injury for determination of appropriate treatment (observation, splenic artery embolization [SAE], or splenic surgery).This HIPAA-compliant retrospective (...) study was approved by the institutional review board, and the requirement for informed consent was waived. Between January 2009 and July 2011, 171 hemodynamically stable patients with blunt splenic injury underwent multidetector CT at admission to the hospital. Images were reviewed by applying a multidetector CT-based grading system, and the amount of hemoperitoneum was quantified. Demographic data, vital signs, laboratory values, injury severity score, abbreviated injury severity, final treatment

2014 Radiology

75. Organ crushing tackle: pancreatic, bowel and splenic artery injury from blunt abdominal trauma playing rugby union Full Text available with Trip Pro

Organ crushing tackle: pancreatic, bowel and splenic artery injury from blunt abdominal trauma playing rugby union 26786533 2016 12 13 2018 11 13 1757-790X 2016 2016 Jan 19 BMJ case reports BMJ Case Rep Organ crushing tackle: pancreatic, bowel and splenic artery injury from blunt abdominal trauma playing rugby union. 10.1136/bcr-2015-214124 bcr2015214124 Moore Timothy T NSW Health, Manly, New South Wales, Australia. eng Case Reports Journal Article 2016 01 19 England BMJ Case Rep 101526291 1757 (...) -790X IM Abdominal Injuries diagnostic imaging etiology pathology surgery Adult Colectomy Football injuries Humans Laparotomy methods Male Pancreas injuries surgery Pancreatectomy Shock, Hemorrhagic diagnosis etiology Splenectomy Splenic Artery injuries surgery Wounds, Nonpenetrating diagnosis etiology pathology surgery 2016 1 21 6 0 2016 1 21 6 0 2016 12 15 6 0 epublish 26786533 bcr-2015-214124 10.1136/bcr-2015-214124 PMC4735394 Acta Radiol. 2015 Apr;56(4):387-96 24760286 N Engl J Med. 1994 Oct

2016 BMJ case reports

76. The spleen as an extramedullary source of inflammatory cells responding to acetaminophen-induced liver injury Full Text available with Trip Pro

The spleen as an extramedullary source of inflammatory cells responding to acetaminophen-induced liver injury Macrophages have been shown to play a role in acetaminophen (APAP)-induced hepatotoxicity, contributing to both pro- and anti-inflammatory processes. In these studies, we analyzed the role of the spleen as an extramedullary source of hepatic macrophages. APAP administration (300mg/kg, i.p.) to control mice resulted in an increase in CD11b(+) infiltrating Ly6G(+) granulocytic and Ly6G (...) (-) monocytic cells in the spleen and the liver. The majority of the Ly6G(+) cells were also positive for the monocyte/macrophage activation marker, Ly6C, suggesting a myeloid derived suppressor cell (MDSC) phenotype. By comparison, Ly6G(-) cells consisted of 3 subpopulations expressing high, intermediate, and low levels of Ly6C. Splenectomy was associated with increases in mature (F4/80(+)) and immature (F4/80(-)) pro-inflammatory Ly6C(hi) macrophages and mature anti-inflammatory (Ly6C(lo)) macrophages

2016 Toxicology and applied pharmacology

77. Laparascopic Splenectomy Due to Splenic Injury after Colonoscopy Full Text available with Trip Pro

Laparascopic Splenectomy Due to Splenic Injury after Colonoscopy Colonoscopy, which is routinely performed in diagnosis and treatment of colorectal disorders, is a reliable procedure. Its most frequent complications are bleeding and perforation. Splenic rupture is a very rarely met complication of colonoscopy, and delay in its diagnosis leads to increased morbidity and mortality. We presented a 69 years old female patient, who was diagnosed by computerized abdominal tomography, performed (...) bleeding, in other words, if there is a sub-capsular hematoma of the spleen, medical management by monitoring the vital signs may be preferred. Then, splenectomy should be performed at an appropriate time.

2016 The Eurasian journal of medicine

78. Comparison of MDCT protocols in trauma patients with suspected splenic injury: superior results with protocol that includes arterial and portal venous phase imaging Full Text available with Trip Pro

Comparison of MDCT protocols in trauma patients with suspected splenic injury: superior results with protocol that includes arterial and portal venous phase imaging We aimed to determine which intravenous contrast-enhanced multidetector computed tomography (MDCT) protocol produced the most accurate results for the detection of splenic vascular injury in hemodynamically stable patients who had sustained blunt abdominal trauma.We retrospectively reviewed 88 patients from 2003 to 2011 who (...) , which includes the arterial phase, in patients with suspected splenic injury and question the utility of obtaining a delayed sequence.

2016 Diagnostic and Interventional Radiology

79. Salmonella typhi Splenic Abscess Following Blunt Abdominal Injury: A Case Report Full Text available with Trip Pro

Salmonella typhi Splenic Abscess Following Blunt Abdominal Injury: A Case Report Splenic abscess as a complication of enteric fever due to Salmonella typhi is a rare entity. Here, we are presenting a case of splenic abscess caused by Salmonella typhi with a blunt injury to the abdomen as the predisposing factor. The patient underwent total splenectomy due to failure of conservative management. Splenic abscess is a potential life threatening disease if left untreated. In spite of its rarity

2016 Journal of clinical and diagnostic research : JCDR

80. Iatrogenic splenic injury: review of the literature and medico-legal issues Full Text available with Trip Pro

Iatrogenic splenic injury: review of the literature and medico-legal issues Iatrogenic splenic injury is a recognized complication in abdominal surgery. The aim of this paper is to understand the medico-legal issues of iatrogenic splenic injuries. We performed a literature review on PubMed and Scopus using iatrogenic splenic or spleen injury and iatrogenic splenic rupture as keywords. Iatrogenic splenic injury cases were identified. Most cases were related to colonoscopy, but we also identified (...) cases related to upper gastrointestinal procedures, colonic surgery, ERCP, left nephrectomy and/or adrenalectomy, percutaneous nephrolithotomy, vascular operations involving the abdominal aorta, gynecological operation, left lung biopsy, chest drain, very rarely spinal surgery and even cardiopulmonary resuscitation. There are several surgical procedures that can lead to a splenic injury. However, from a medico-legal point of view, it is important to assess whether the cause can be attributed

2016 Open Medicine

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