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Splenic Injury

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2741. Occult splenic injury: delayed presentation manifesting as jaundice Full Text available with Trip Pro

Occult splenic injury: delayed presentation manifesting as jaundice Delayed splenic rupture, though uncommon, is a recognised clinical condition and is associated with a significant mortality rate. In the vast majority of cases the patient re-presents with abdominal symptoms and/or signs of acute intraperitoneal haemorrhage. A case is presented of delayed splenic rupture presenting with jaundice attributable to intra-abdominal clot lysis.

2001 Emergency Medicine Journal : EMJ

2742. Management of adult splenic injuries in Ontario: a population-based study Full Text available with Trip Pro

Management of adult splenic injuries in Ontario: a population-based study To determine the population-based incidence of splenic injuries in the Province of Ontario, the proportion of splenic injuries treated by observation, splenectomy and splenorrhaphy, changes in management over time and the variation in management of splenic injuries among Ontario hospitals.A retrospective cohort study.All adults (older than 16 years) admitted with a diagnosis of splenic injury (clinical modification (...) of the International Classification of Diseases, 9th revision) to acute care hospitals in Ontario between 1991 and 1994, identified from the Ontario Trauma Registry.The incidence of splenic injury was 1.7 cases per 1000 trauma admissions per year. Patients with splenic injury were young (median age 32 years) and male (71%), and the death rate was 8%. Observation was the commonest method of treatment (69%), followed by splenectomy (28%) and splenorrhaphy (4%). The use of observation increased over the study period

2000 Canadian Journal of Surgery

2743. Blunt splenic injuries in a Canadian pediatric population: the need for a management guideline Full Text available with Trip Pro

Blunt splenic injuries in a Canadian pediatric population: the need for a management guideline To review practice patterns in a Canadian pediatric centre and develop a safe and effective care plan for managing children with splenic injuries.A chart review.Winnipeg Children's Hospital.All patients with splenic injuries under the age of 17 years admitted to the hospital between December 1994 and April 1999.These included patient demographics, length of stay, location of care, grade of splenic (...) injury (American Association for the Surgery of Trauma Organ Injury Scale), imaging tests performed in hospital and after discharge, follow-up care and time to return to full activity.Forty-four patients received nonoperative management. The mean age of the patients was 10.4 years. The average grade of splenic injury was 2.8. Sixteen patients (36%) were admitted to the intensive care unit for an average of 1.9 days. Mobilization was allowed after a mean of 5.2 days. Average length of hospital stay

2002 Canadian Journal of Surgery

2744. Portal hyperperfusion injury as the cause of primary nonfunction in a small-for-size liver graft-successful treatment with splenic artery ligation. (Abstract)

Portal hyperperfusion injury as the cause of primary nonfunction in a small-for-size liver graft-successful treatment with splenic artery ligation. Dysfunction of a small-for-size graft is an important clinical problem after living donor liver transplantation in adults. We report a case of primary nonfunction after a small-for-size right lobe living donor liver transplant that was successfully salvaged by reduction of portal pressure and blood flow after splenic artery ligation. The case (...) established portal hyperperfusion injury as a cause of primary nonfunction in a small-for-size graft and we recommend that portal pressure be measured when clinical suspicion arises. Splenic artery ligation is a technically simple procedure that can be applied for the prevention or treatment of such injury.

2003 Liver Transplantation

2745. Kupffer cells modulate splenic interleukin-10 production in endotoxin-induced liver injury after partial hepatectomy. (Abstract)

Kupffer cells modulate splenic interleukin-10 production in endotoxin-induced liver injury after partial hepatectomy. This study was conducted to investigate the implication of Kupffer cells and the spleen in interleukin (IL)-10 production in endotoxin-induced liver injury after hepatectomy.Rats were divided into five groups: the S group, sham-operation; the SG group, sham-operation followed by intravenous gadolinium chloride (GdCl(3): 7 mg/kg) administration to inhibit Kupffer cell function (...) , marked increase in plasma IL-10 levels associated with enhanced splenic IL-10 mRNA was observed 1 h after lipopolysaccharide administration when compared to those in the H and HGS groups. Plasma TNF-alpha/IL-10 ratio 1 h after lipopolysaccharide administration was higher in the order of H, HGS and HG groups. Hepatic parenchymal damage and the 24-h mortality were lowest in group HG, followed by groups HGS and H.Kupffer cells after hepatectomy may aggravate endotoxin-induced liver injury via down

2003 Journal of Hepatology

2746. Clinical Findings in Patients with Splenic Injuries: Are Injuries to the Left Lower Chest Important? Full Text available with Trip Pro

Clinical Findings in Patients with Splenic Injuries: Are Injuries to the Left Lower Chest Important? 20852694 2011 07 14 2016 10 21 1948-3384 2 3 2001 Jul The California journal of emergency medicine Cal J Emerg Med Clinical findings in patients with splenic injuries: are injuries to the left lower chest important? 33-6 Schneir A A Division of Emergency Medicine, UC San Diego School of Medicine and. Holmes J F JF eng Journal Article United States Cal J Emerg Med 101527253 1948-3384 2010 9 21 6

2001 The California Journal of Emergency Medicine

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