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Splenic Injury

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181. Scintigraphic Diagnosis of Splenic Injuries (PubMed)

Scintigraphic Diagnosis of Splenic Injuries 18747584 2010 06 30 2018 11 13 0093-0415 123 5 1975 Nov The Western journal of medicine West. J. Med. Scintigraphic diagnosis of splenic injuries. 390-1 Siemsen J K JK Telfer N N eng Journal Article United States West J Med 0410504 0093-0415 1975 11 1 0 0 1975 11 1 0 1 1975 11 1 0 0 ppublish 18747584 PMC1129925 Surg Clin North Am. 1972 Jun;52(3):667-85 5037648 Radiology. 1974 Mar;110(3):609-14 4811682 J Trauma. 1974 Mar;14(3):197-9 4814395

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1975 Western Journal of Medicine

182. Roentgenologic Examination of the Abdomen as an Aid in the Early Diagnosis of Splenic Injury (PubMed)

Roentgenologic Examination of the Abdomen as an Aid in the Early Diagnosis of Splenic Injury 17858547 2007 09 17 2008 11 20 0003-4932 121 1 1945 Jan Annals of surgery Ann. Surg. Roentgenologic Examination of the Abdomen as an Aid in the Early Diagnosis of Splenic Injury. 111-9 O'neill J F JF Rousseau J P JP eng Journal Article United States Ann Surg 0372354 0003-4932 1945 1 1 0 0 1945 1 1 0 1 1945 1 1 0 0 ppublish 17858547 PMC1618069

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1945 Annals of Surgery

183. Splenosis: The Autotransplantation of Splenic Tissue Following Injury to the Spleen : Report of Two Cases and Review of the Literature (PubMed)

Splenosis: The Autotransplantation of Splenic Tissue Following Injury to the Spleen : Report of Two Cases and Review of the Literature 13627998 2000 07 01 2018 12 01 0003-4932 149 3 1959 Mar Annals of surgery Ann. Surg. Splenosis: the autotransplantation of splenic tissue following injury to the spleen; report of two cases and review of the literature. 402-14 COTLAR A M AM CERISE E J EJ eng Journal Article United States Ann Surg 0372354 0003-4932 OM Humans Spleen Splenosis Transplantation

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1959 Annals of Surgery

184. Level-Specific Differences in Systemic Expression of Pro- and Anti-Inflammatory Cytokines and Chemokines after Spinal Cord Injury (PubMed)

Level-Specific Differences in Systemic Expression of Pro- and Anti-Inflammatory Cytokines and Chemokines after Spinal Cord Injury While over half of all spinal cord injuries (SCIs) occur in the cervical region, the majority of preclinical studies have focused on models of thoracic injury. However, these two levels are anatomically distinct-with the cervical region possessing a greater vascular supply, grey-white matter ratio and sympathetic outflow relative to the thoracic region (...) - and anti-inflammatory proteins relative to thoracic SCI, likely due to sympathetic dysregulation associated with higher level SCIs. However, contrary to the literature, we did not observe level-dependent splenic atrophy with our incomplete SCI model. This is the first study to compare the systemic plasma-level changes following cervical and thoracic SCI using level-matched and time-matched controls. The results of this study provide the first evidence in support of level-targeted intervention and also

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2018 International journal of molecular sciences

185. Surgical Strategy Based on Indocyanine Green Test for Chemotherapy-Associated Liver Injury and Long-Term Outcome in Colorectal Liver Metastases. (PubMed)

Surgical Strategy Based on Indocyanine Green Test for Chemotherapy-Associated Liver Injury and Long-Term Outcome in Colorectal Liver Metastases. It remains unclear whether the presence of chemotherapy-induced liver injury (CALI) or impaired liver functional reserve affects the long-term outcome. This study assessed the applicability and long-term effects of using criteria based on the indocyanine green (ICG) test results in selecting the operative procedure among patients with colorectal liver (...) , 161 patients were included; 77 of them had an ICG R15 > 10%, and 57 had pathological liver injury (PLI). After the median follow-up time of 30.9 months, the 5-year overall survival rate was 36.1%. The presence of an impaired ICG test result or CALI did not negatively impact the overall and recurrence-free survival outcomes. A multivariate analysis revealed that the presence of four or more nodules of liver metastases was the only independent predictor of a poor overall survival. A significantly

2018 Journal of Gastrointestinal Surgery

186. The Addition of Bevacizumab to Oxaliplatin-Based Chemotherapy: Impact Upon Hepatic Sinusoidal Injury and Thrombocytopenia. (PubMed)

The Addition of Bevacizumab to Oxaliplatin-Based Chemotherapy: Impact Upon Hepatic Sinusoidal Injury and Thrombocytopenia. Oxaliplatin-based chemotherapy can cause hepatic sinusoidal injury (HSI), portal hypertension, and splenic sequestration of platelets. Evidence suggests that bevacizumab may protect against HSI.Two cohorts of metastatic colorectal cancer (CRC) were analyzed: a nonrandomized exploratory cohort of 184 patients treated at a single institution from 2003 to 2010 (...) and a confirmatory cohort of 200 patients from a multi-institutional randomized trial (NO16966). All patients were treated with frontline fluoropyrimidine and oxaliplatin with or without bevacizumab. Changes in splenic volumes and platelet counts were compared by treatment, two-sided log-rank test.In the exploratory cohort, the bevacizumab-treated patients (n = 138) compared with the nonbevacizumab-treated patients (n = 46) demonstrated a longer median time to splenic enlargement (≥30%, P = .02) and reduced rate

2018 Journal of the National Cancer Institute

187. Management of intra-abdominal vascular injury in trauma laparotomy: a South African experience (PubMed)

and 17 mesenteric) and 74 venous injuries (including 21 renal and 17 inferior vena caval). Combined venous and arterial injuries were found in almost one-third of patients (34 [30.9%]). Fifty-seven patients (51.8%) required intensive care admission. The overall mortality rate was 28.2% (31 patients); the rate was 62% for aortic injuries and 47% for inferior vena cava injuries. Liver injury, large bowel injury, splenic injury and elevated lactate level were all associated with a statistically (...) Management of intra-abdominal vascular injury in trauma laparotomy: a South African experience Intra-abdominal vascular injury (IAVI) is uncommon but continues to be associated with high mortality rates despite technological advances in the past decades. In light of these ongoing developments, we reviewed our contemporary experience with IAVI in an attempt to clarify and refine our management strategies and the outcome of these patients.We retrospectively reviewed the charts of all patients

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2018 Canadian Journal of Surgery

188. Equestrian Injury Presentations to a Regional Trauma Centre in Ireland (PubMed)

more females involved in equestrian injuries than males (58% versus 42%). Falling from a horse contributed to significantly more presentations and admissions than any other cause. 36% of presentations were associated with a radiological abnormality. Types of injuries identified included skeletal fractures (27.5%), joint dislocation/subluxation (5%), concussion (12.5%), and splenic laceration/intraperitoneal haemorrhage (1%). Admission or transfer to tertiary care was required for 18% of equestrian (...) Equestrian Injury Presentations to a Regional Trauma Centre in Ireland The Irish Equestrian industry provides over 12,500 full time job equivalents contributing in excess of €454 million to the Irish economy annually. For such an important industry there is a paucity of information relating to equestrian injuries.The aim of this study was to determine the demographics, characteristics, and outcomes of equestrian related injuries presenting to the emergency department of a regional trauma centre

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2018 Emergency medicine international

189. A case of splenic rupture: a rare event after laparoscopic cholecystectomy. (PubMed)

A case of splenic rupture: a rare event after laparoscopic cholecystectomy. Laparoscopic cholecystectomy (LC) is generally safe and well-accepted. In rare cases, it is associated with complications (intra- e postoperative bleeding, visceral injury and surgical site infection). Splenic lesion has been reported only after direct trauma. We report an unusual case of splenic rupture presenting after "uncomplicated" LC.A 77-year-old woman presented with distended abdomen, tenderness in the left (...) upper quadrant and severe anemia 12 hours after LC. Clinical examination revealed hypovolemic shock. Abdominal computed tomography confirmed the diagnosis of splenic rupture, and the patient required an urgent splenectomy through midline incision. The post-operative course was uneventful and the patient was discharged on 7th postoperative day.Splenic injury rarely complicates LC. We postulate that congenital or post-traumatic adhesions of the parietal peritoneum to the spleen may have been stretched

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2014 BMC Surgery

190. Microwave Ablation and Partial Splenic Embolization in the Management of Hypersplenism

for the eradication of local tumor tissue within solid organs. There have been reports of the use of radiofrequency to ablate normal spleen, splenic injury, and splenomegaly. Radiofrequency Ablation (RFA) had comparable efficacy and a better safety than PSE in the treatment of hypersplenism in patients with post hepatitis c cirrhosis. MW ablation performed either laparoscopically or percutaneously is a safe, effective, and minimally invasive technique for the management of hypersplenism in patients with liver (...) Microwave Ablation and Partial Splenic Embolization in the Management of Hypersplenism Microwave Ablation and Partial Splenic Embolization in the Management of Hypersplenism - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies

2014 Clinical Trials

191. Splenic Avulsion Following PEG Tube Placement: A Rare but Serious Complication (PubMed)

of intra-abdominal bleeding secondary to catastrophic splenic injury 12 hours after PEG tube placement resulting in hemodynamic compromise. The patient underwent splenectomy and had an uneventful recovery. (...) Splenic Avulsion Following PEG Tube Placement: A Rare but Serious Complication Placement of a percutaneous endoscopic gastrostomy (PEG) tube is a common procedure to allow for enteral nutrition in patients with multiple indications. PEG tube placement is a safe procedure with minor complications such as site infection and irritation. One of the more severe complications is splenic laceration, which may result in intra-peritoneal bleeding and manifest as an acute abdomen. We present a rare case

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2014 ACG case reports journal

192. Splenic artery embolisation in children and adolescents-an 8 year experience. (PubMed)

Splenic artery embolisation in children and adolescents-an 8 year experience. Non-operative management (NOM) is the treatment of choice in blunt splenic injuries in the paediatric population, with reported success rates exceeding 90%. Splenic artery embolisation (SAE) was added to our institutional treatment protocol for splenic injury in 2002. We wanted to review indications for SAE and the clinical outcome of splenic injury management in children admitted between August 1, 2002 and July 31 (...) , 2010.Patients aged <17 years with splenic injury were identified in the institutional trauma and medical code registries. Patient charts and computed tomographic (CT) scans were reviewed.Of the 72 children and adolescents with splenic injury included during the 8 year study period, 66 patients (92%) were treated non-operatively and six underwent operative management. Severe splenic injury (OIS grade 3-5) was diagnosed in 67 patients (93%). SAE was performed in 22 of the NOM patients. Indications

2014 Injury

193. Ruptured Splenic Artery Aneurysms and the Use of an Adapted Fast Protocol in Reproductive Age Women with Hemodynamic Collapse: Case Series (PubMed)

with hemodynamic collapse, the role of traditional imaging is limited mainly due to the critical condition of the patient. Bedside ultrasound has emerged as a diagnostic imaging resource in patients with undifferentiated hypotension and in patients with traumatic injuries. However, its use has not been studied specifically in the female population. We present two patients with ruptured splenic artery aneurysms, discuss the role of bedside ultrasound in their management, and introduce a new ultrasound protocol (...) Ruptured Splenic Artery Aneurysms and the Use of an Adapted Fast Protocol in Reproductive Age Women with Hemodynamic Collapse: Case Series Nontraumatic symptomatic hypotension in all patients requires prompt diagnosis and appropriate treatment for optimum outcome. The female population specifically has an expanded differential diagnosis that should be considered when these patients present with hemodynamic collapse. While the most common causes of hypotension in pregnant patients

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2014 Case Reports in Emergency Medicine

194. Hemoperitoneum due to Splenic Laceration Caused by Colonoscopy: A Rare and Catastrophic Complication (PubMed)

was found on CT scan. Splenic injury was found few hours later on the day of colonoscopy. It might result from the extra tension between the spleen and splenic flexure which varies from different positions of patients. (...) Hemoperitoneum due to Splenic Laceration Caused by Colonoscopy: A Rare and Catastrophic Complication Numerous studies suggest that in asymptomatic patients, routine follow-up CT is not indicated due to the insignificant findings found on these patients. A 53-year-old man, who denied any underlying disease before, underwent colonoscopy for routine health examination. Sudden onset of abdominal pain around left upper quarter was mentioned at our emergency department. Grade II spleen laceration

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2014 Case Reports in Emergency Medicine

195. Antibody Response to a T-Cell-Independent Antigen Is Preserved after Splenic Artery Embolization for Trauma (PubMed)

Antibody Response to a T-Cell-Independent Antigen Is Preserved after Splenic Artery Embolization for Trauma Splenic artery embolization (SAE) is increasingly being used as a nonoperative management strategy for patients with blunt splenic injury following trauma. The aim of this study was to assess the splenic function of patients who were embolized. A clinical study was performed, with splenic function assessed by examining the antibody response to polysaccharide antigens (pneumococcal 23 (...) (5.29; P = 0.90); however, the median response of the splenectomized patients (2.30) did differ (P = 0.003). In 2 of the proximally embolized patients and none of the distally embolized patients, the ratio of the IgG antibody level postvaccination compared to that prevaccination was <2. There were no significant differences in the absolute numbers of lymphocytes or B-cell subsets between the SAE patients and the HC. HJB were not observed in the SAE patients. The splenic immune function of embolized

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2014 Clinical and vaccine immunology : CVI

196. Splenic Infarct (Overview)

with multiple blunt injuries who required hepatic packing as part of a damage-control procedure. At initial exploration, the spleen was intact, perfused, and viable. The patient subsequently required reoperation for release of an intra-abdominal compartment syndrome. Follow-up CT after the second operation revealed global splenic infarction, attributed to an occlusion of splenic venous outflow due to severe intra-abdominal hypertension and the resultant impedance of venous return from the visceral (...) of blunt splenic injuries Increased use of angiographic embolization for vascular splenic injuries [ ] Previous Next: Prognosis The prognosis for splenic infarction varies according to the underlying disease process responsible for the infarct. Splenectomies for infarction of massively enlarged spleens accompanying hematologic malignancies reportedly are associated with mortalities as high as 35%. At the other end of the spectrum, many infarcts are clinically occult, with no significant long-term

2014 eMedicine Surgery

197. Splenic Rupture (Overview)

Author: H Scott Bjerke, MD, FACS; Chief Editor: John Geibel, MD, DSc, MSc, AGAF Share Email Print Feedback Close Sections Sections Splenic Rupture Overview Background Although protected under the bony ribcage, the spleen remains the most commonly affected organ in blunt injury to the abdomen in all age groups. While some references occasionally document liver injuries as being more common, blunt injuries to the spleen are documented more frequently as the primary solid organ injury in the abdomen (...) . These injuries are common in both rural and urban environments and result from motor vehicle crashes, domestic violence, sporting events, and accidents involving bicycle handlebars. See the images below. Intra-parenchymal blush observed on helical CT scan. Grade 4-5 splenic laceration on helical CT scan. A general surgeon in a community hospital is just as likely to observe and treat a splenic injury as the full-time trauma surgeon in an –verified Level 1 or Level 2 trauma center. For this reason, all

2014 eMedicine Surgery

198. Splenic Abscess (Overview)

upper pole can fistulize into the pleura. Abscesses originating from the lower pole can involve the splenic flexure and communicate with the colonic lumen. The stomach and pancreas can be affected in an analogous way. [ ] Previous Next: Pathophysiology Splenic abscesses occur in a variety of clinical scenarios. Published studies suggest that preexisting splenic tissue injury and bacteremia are required to form a basis for an abscess. [ , ] Published scenarios include the following: Hematogenous (...) Splenic Abscess (Overview) Splenic Abscess: Background, Anatomy, Pathophysiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTk0NjU1LW92ZXJ2aWV3 processing > Splenic Abscess Updated: Jul 20, 2018 Author

2014 eMedicine Surgery

199. Splenic Infarct (Diagnosis)

with multiple blunt injuries who required hepatic packing as part of a damage-control procedure. At initial exploration, the spleen was intact, perfused, and viable. The patient subsequently required reoperation for release of an intra-abdominal compartment syndrome. Follow-up CT after the second operation revealed global splenic infarction, attributed to an occlusion of splenic venous outflow due to severe intra-abdominal hypertension and the resultant impedance of venous return from the visceral (...) of blunt splenic injuries Increased use of angiographic embolization for vascular splenic injuries [ ] Previous Next: Prognosis The prognosis for splenic infarction varies according to the underlying disease process responsible for the infarct. Splenectomies for infarction of massively enlarged spleens accompanying hematologic malignancies reportedly are associated with mortalities as high as 35%. At the other end of the spectrum, many infarcts are clinically occult, with no significant long-term

2014 eMedicine Surgery

200. Splenic Abscess (Diagnosis)

upper pole can fistulize into the pleura. Abscesses originating from the lower pole can involve the splenic flexure and communicate with the colonic lumen. The stomach and pancreas can be affected in an analogous way. [ ] Previous Next: Pathophysiology Splenic abscesses occur in a variety of clinical scenarios. Published studies suggest that preexisting splenic tissue injury and bacteremia are required to form a basis for an abscess. [ , ] Published scenarios include the following: Hematogenous (...) Splenic Abscess (Diagnosis) Splenic Abscess: Background, Anatomy, Pathophysiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTk0NjU1LW92ZXJ2aWV3 processing > Splenic Abscess Updated: Jul 20, 2018 Author

2014 eMedicine Surgery

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