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Spitz Nevus

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1. Clinical and dermoscopic features of Spitz nevus by sex, age and anatomical site: a study of 913 Spitz naevi. (Abstract)

Clinical and dermoscopic features of Spitz nevus by sex, age and anatomical site: a study of 913 Spitz naevi. 29569227 2018 09 17 1365-2133 179 3 2018 Sep The British journal of dermatology Br. J. Dermatol. Clinical and dermoscopic features of Spitz naevus by sex, age and anatomical site: a study of 913 Spitz naevi. 769-770 10.1111/bjd.16564 Scalvenzi M M Section of Dermatology, Department of Clinical Medicine and Surgery, Dermatology Unit, University of Naples Federico II, Via Pansini, 5

2018 British Journal of Dermatology

2. Clinico-Dermoscopic Features of Spitz Naevi by Age and Anatomic Site: A Study of 378 Spitz Naevi. (Abstract)

Clinico-Dermoscopic Features of Spitz Naevi by Age and Anatomic Site: A Study of 378 Spitz Naevi. 28346660 2018 08 28 2018 08 28 1365-2133 177 4 2017 10 The British journal of dermatology Br. J. Dermatol. Clinicodermoscopic features of Spitz naevi by age and anatomical site: a study of 378 Spitz naevi. e152-e153 10.1111/bjd.15501 de Mestier Y Y Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan. Moscarella E E 0000-0001-5160-8997 Dermatology and Skin Cancer Unit (...) of Dermatology, Medical University of Graz, Graz, Austria. Hofmann-Wellenhof R R Department of Dermatology, Medical University of Graz, Graz, Austria. Argenziano G G Dermatology Unit, Second University of Naples, Naples, Italy. eng Letter Observational Study 2017 10 01 England Br J Dermatol 0004041 0007-0963 IM Adolescent Adult Age Distribution Aged Child Child, Preschool Dermoscopy Female Head and Neck Neoplasms epidemiology pathology Humans Infant Infant, Newborn Italy epidemiology Male Middle Aged Nevus

2017 British Journal of Dermatology

3. Agminated Spitz naevi or metastatic spitzoid melanoma? Full Text available with Trip Pro

Agminated Spitz naevi or metastatic spitzoid melanoma? 29405264 2019 03 20 2019 03 20 1440-0960 59 3 2018 Aug The Australasian journal of dermatology Australas. J. Dermatol. Agminated Spitz naevi or metastatic spitzoid melanoma? e234-e235 10.1111/ajd.12781 van Kester Marloes Sophia MS http://orcid.org/0000-0001-9442-0898 Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands. Eggen Celine C Department of Dermatology, Erasmus Medical Center, Rotterdam (...) Melanoma pathology surgery Neoplasm Recurrence, Local pathology Neoplasms, Second Primary pathology Nevus, Epithelioid and Spindle Cell pathology surgery Positron-Emission Tomography methods Risk Assessment Sentinel Lymph Node Biopsy methods Skin Neoplasms pathology surgery 2018 2 7 6 0 2019 3 21 6 0 2018 2 7 6 0 ppublish 29405264 10.1111/ajd.12781 PMC6099432 Pathology. 2016 Feb;48(2):113-31 27020384 Lancet Oncol. 2014 Apr;15(4):e178-83 24694641 Pediatr Dermatol. 2013 Sep-Oct;30(5):e104-5 23278340 Am J

2018 The Australasian journal of dermatology

4. Update on dermoscopy of Spitz/Reed naevi and management guidelines by the International Dermoscopy Society. (Abstract)

Update on dermoscopy of Spitz/Reed naevi and management guidelines by the International Dermoscopy Society. Spitzoid lesions represent a challenging and controversial group of tumours, in terms of clinical recognition, biological behaviour and management strategies. Although Spitz naevi are considered benign tumours, their clinical and dermoscopic morphological overlap with spitzoid melanoma renders the management of spitzoid lesions particularly difficult. The controversy deepens because (...) of the existence of tumours that cannot be safely histopathologically diagnosed as naevi or melanomas (atypical Spitz tumours). The dual objective of the present study was to provide an updated classification on dermoscopy of Spitz naevi, and management recommendations of spitzoid-looking lesions based on a consensus among experts in the field. After a detailed search of the literature for eligible studies, a data synthesis was performed from 15 studies on dermoscopy of Spitz naevi. Dermoscopically, Spitz

2017 British Journal of Dermatology

5. Mosaic pathogenic HRAS variant in a patient with nevus spilus with agminated Spitz nevi and parametrial-uterine rhabdomyosarcoma. (Abstract)

Mosaic pathogenic HRAS variant in a patient with nevus spilus with agminated Spitz nevi and parametrial-uterine rhabdomyosarcoma. 29193020 2019 02 19 1365-2133 178 3 2018 03 The British journal of dermatology Br. J. Dermatol. Mosaic pathogenic HRAS variant in a patient with nevus spilus with agminated Spitz nevi and parametrial-uterine rhabdomyosarcoma. 804-806 10.1111/bjd.16155 Nemeth K K Department of Dermatology, Medical College of Wisconsin, Milwaukee, WI, U.S.A. Szabo S S Division

2017 British Journal of Dermatology

6. Parallel ridge dermoscopic pattern in plantar atypical Spitz nevus. (Abstract)

Parallel ridge dermoscopic pattern in plantar atypical Spitz nevus. 28862772 2018 03 14 1468-3083 32 3 2018 Mar Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol Parallel ridge dermoscopic pattern in plantar atypical Spitz nevus. e101-e102 10.1111/jdv.14575 Jurakić Tončić R R University Department of Dermatology and Venereology, School of Medicine, University Hospital Center, Zagreb, Croatia. Bradamante M M University Department of Dermatology

2017 Journal of the European Academy of Dermatology and Venereology

7. THE FAST CLINICAL EVOLUTION OF A SPITZ NEVUS: THREE-YEAR FOLLOW-UP OF A CHILD Full Text available with Trip Pro

THE FAST CLINICAL EVOLUTION OF A SPITZ NEVUS: THREE-YEAR FOLLOW-UP OF A CHILD To report the clinical evolution and handling of a Spitz nevus, from its initial flat feature to becoming an irregular, nodular, reddish lesion.Female child, phototype II, with a small congenital nevus on the left lower limb and other sustained small nevi. The patient went through annual clinical and dermoscopic evaluations between the ages of three and seven, period during which the nevi located on the left thigh (...) grew rapidly. The clinical hypothesis was Spitz nevus, with indication of surgical removal with a safety margin and anatomopathological study. Considering patient's age and clinical/histological aspects, the diagnosis of Spitz nevus was confirmed.Initial globular pattern and size under 5 mm upon dermoscopy allowed clinical follow-up. However, onset of hyperchromia and rapid growing of the lesion, along with aesthetic concerns, possibility of trauma in the region, and risk of malignancy at puberty

2017 Revista Paulista de Pediatria

8. Spitz Nevus

Spitz Nevus Spitz Nevus Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Spitz Nevus Spitz Nevus Aka: Spitz Nevus , Benign Juvenile (...) Melanoma II. Epidemiology Most common in children III. Pathophysiology Not a cancer (named only for it's similarity of histology to ) Increased vascular supply gives the lesion its color IV. Signs less Red to red-brown dome-shaped s to s Variable surface (smooth to verrucous) Size varies from 0.3 to 1.5 cm Typically of sudden onset V. Management Excise due to histologic similarities to Alert pathologist to the gross examination findings suggestive of Spitz Nevus VI. Reference Habif (2003) Clinical

2018 FP Notebook

9. Atypical Spitz Tumor Arising on a Congenital Linear Plaque-Type Blue Nevus: A Case Report With a Review of the Literature on Plaque-Type Blue Nevus Full Text available with Trip Pro

Atypical Spitz Tumor Arising on a Congenital Linear Plaque-Type Blue Nevus: A Case Report With a Review of the Literature on Plaque-Type Blue Nevus The plaque-type blue nevus (PTBN) is a rare variant of blue nevus, of which only a few reports are described. A nodular growth within a preexistent PTBN should always alert to the possibility of malignant transformation. The authors report the first case of an atypical Spitz tumor arising on a congenital linear PTBN in a 60-year-old woman (...) . The diagnosis of "atypical Spitz tumor" is here used to describe a microscopic "gray zone" in which it is not possible to differentiate with adequate certainty between a Spitz nevus and a spitzoid melanoma. This report adds to and summarizes the small body of literature describing PTBN and discusses diagnostic and clinical implications.

2015 The American Journal of dermatopathology

10. Human polyomavirus DNA detection in keratoacanthoma and Spitz naevus: no evidence for a causal role. (Abstract)

Human polyomavirus DNA detection in keratoacanthoma and Spitz naevus: no evidence for a causal role. Keratoacanthomas (KA) and Spitz naevus (SN) are both lesions with unknown aetiology; therefore, the possibility of a viral involvement, more specifically the involvement of human polyomaviruses (HPyV), was investigated. In total, 22 cases of KA and 25 cases of SN were tested for the presence of HPyVs. DNA was extracted and amplified by multiplex PCR and thereafter tested with a multiplex bead

2016 Journal of Clinical Pathology

11. Spitz naevi and melanomas with similar dermoscopic pattern: can confocal microscopy differentiate? (Abstract)

Spitz naevi and melanomas with similar dermoscopic pattern: can confocal microscopy differentiate? Differentiating Spitz naevi from melanomas can be difficult both clinically and dermoscopically. Previous studies have reported the potential role of in vivo reflectance confocal microscopy (RCM) in increasing diagnostic accuracy.To define RCM criteria that can differentiate 'false twins', namely Spitz naevi and melanomas sharing similar dermoscopic appearance.Lesions histopathologically diagnosed (...) as Spitz naevi or melanomas were retrospectively retrieved. They were selected to cover all dermoscopic types and were put into couples sharing similar aspects. Lesions were classified into three main dermoscopic categories: globular and starburst pattern, spitzoid with dotted vessels, and multicomponent or aspecific pattern.RCM findings revealed that striking cell pleomorphism within the epidermis, widespread atypical cells at the dermoepidermal junction and marked pleomorphism within nests were

2015 British Journal of Dermatology

12. Spitz Nevus on the Perianal Area of a Child: An Unusual Location Full Text available with Trip Pro

Spitz Nevus on the Perianal Area of a Child: An Unusual Location 26719661 2015 12 31 2018 11 13 1013-9087 27 6 2015 Dec Annals of dermatology Ann Dermatol Spitz Nevus on the Perianal Area of a Child: An Unusual Location. 787-8 10.5021/ad.2015.27.6.787 Lee Dong Yeup DY Department of Dermatology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea. Baek Jong Heon JH Department of Dermatology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea. Kim Dong

2015 Annals of dermatology

13. Spitz Nevus Arising in the Eyelid of a Teenager. (Abstract)

Spitz Nevus Arising in the Eyelid of a Teenager. A 16-year-old boy developed over a 2-month interval a lightly pigmented left upper eyelid lesion measuring 1.5 mm in greatest diameter that, when excised, microscopically was hypercellular and composed almost exclusively of nonpigmented epithelioid cells that created florid, large intraepidermal junctional nests and sheets and nests of subepidermal cells. The diagnosis was a Spitz nevus. HMB-45, MART-1, and microphthalmia-associated transcription (...) factor were all positive and established the melanocytic nature of the benign tumor. The Ki-67 proliferation index (5%) and 2 mitoses/mm(2) were both low; p16 protein was immunohistochemically identified in the nevoid cells. We review the clinical, histopathologic, and other immunohistochemical features of this entity and provide a brief differential diagnosis (including separation from a Spitzoid melanoma). This is only the third eyelid Spitz nevus reported in the literature and is the most fully

2015 Survey of Ophthalmology

14. Evolution of pigmented Spitz nevi with starburst pattern during childhood. Full Text available with Trip Pro

Evolution of pigmented Spitz nevi with starburst pattern during childhood. 29906309 2019 01 18 1468-3083 33 1 2019 Jan Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol Evolution of pigmented Spitz naevi with starburst pattern during childhood. e29-e30 10.1111/jdv.15138 Brancaccio G G http://orcid.org/0000-0001-8982-9410 Dermatology Unit, University of Campania, Naples, Italy. Brunetti B B Ospedale Santa Maria della Speranza, Battipaglia, Italy

2018 Journal of the European Academy of Dermatology and Venereology

15. Eruptive disseminated Spitz naevus (EDSN) in a young girl of Indian origin. (Abstract)

Eruptive disseminated Spitz naevus (EDSN) in a young girl of Indian origin. Eruptive disseminated Spitz naevus (EDSN) is a rare entity and has never been documented in a South-east Asian individual (of Indian origin) previously. We report an adolescent with this condition which, to our knowledge, has only been previously reported a few times. © 2014 The Australasian College of Dermatologists.

2014 Australasian Journal of Dermatology

16. Spitz Nevus (Overview)

Spitz Nevus (Overview) Spitz Nevus: Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA1OTYyMy1vdmVydmlldw== processing > Spitz Nevus Updated: Jan 08, 2018 Author: Zoltan (...) Trizna, MD, PhD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Spitz Nevus Overview Background Physicians have known for almost a century that some childhood lesions histologically diagnosed as did not show malignant behavior. The terms juvenile melanoma and prepubertal melanoma were used to describe such lesions. Several attempts were made to establish objective criteria that would clearly delineate Spitz nevi and melanomas. The controversial classification

2014 eMedicine.com

17. Spitz Nevus (Treatment)

Spitz Nevus (Treatment) Spitz Nevus Treatment & Management: Surgical Care, Consultations, Activity Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA1OTYyMy10cmVhdG1lbnQ= processing > Spitz Nevus Treatment (...) & Management Updated: Jan 08, 2018 Author: Zoltan Trizna, MD, PhD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Spitz Nevus Treatment Surgical Care Excision of lesions suspected of being Spitz nevi with histopathologic evaluation of the margins of the specimen is indicated. [ , ] Sentinel lymph node biopsy is not justified for surgical staging. [ ] Next: Consultations Consult a plastic surgeon or head and neck surgeon if the excision requires extensive repair. Previous

2014 eMedicine.com

18. Spitz Nevus (Follow-up)

Spitz Nevus (Follow-up) Spitz Nevus Treatment & Management: Surgical Care, Consultations, Activity Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA1OTYyMy10cmVhdG1lbnQ= processing > Spitz Nevus Treatment (...) & Management Updated: Jan 08, 2018 Author: Zoltan Trizna, MD, PhD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Spitz Nevus Treatment Surgical Care Excision of lesions suspected of being Spitz nevi with histopathologic evaluation of the margins of the specimen is indicated. [ , ] Sentinel lymph node biopsy is not justified for surgical staging. [ ] Next: Consultations Consult a plastic surgeon or head and neck surgeon if the excision requires extensive repair. Previous

2014 eMedicine.com

19. Spitz Nevus (Diagnosis)

Spitz Nevus (Diagnosis) Spitz Nevus: Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA1OTYyMy1vdmVydmlldw== processing > Spitz Nevus Updated: Jan 08, 2018 Author: Zoltan (...) Trizna, MD, PhD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Spitz Nevus Overview Background Physicians have known for almost a century that some childhood lesions histologically diagnosed as did not show malignant behavior. The terms juvenile melanoma and prepubertal melanoma were used to describe such lesions. Several attempts were made to establish objective criteria that would clearly delineate Spitz nevi and melanomas. The controversial classification

2014 eMedicine.com

20. Patients with Spitz nevi in the Greek population: Epidemiologic, Clinical, and histopathological characteristics. (Abstract)

Patients with Spitz nevi in the Greek population: Epidemiologic, Clinical, and histopathological characteristics. Spitz naevi may present with clinical and histopathological atypical features that do not affect patient prognosis but may become worrisome for patients ≥40 years presenting with newly appearing SN.Patient characteristics and sun behaviour patterns were investigated in correlation with age. SN characteristics and histopathological attributes were also investigated in correlation (...) with age.Patients with histopathologically confirmed diagnosis of SN were invited for a clinical examination. Data such as skin type, number of banal/atypical naevi, sun exposure patterns and personal/family history were collected. Histopathology preparations were re-examined by two different histopathologists, and characteristics were collected based on a prespecified checklist. Patients were afterwards followed up every 6 months.A total of 110 patients with SN were identified and assigned to three age groups

2017 Journal of the European Academy of Dermatology and Venereology

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