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Speech Delay

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121. Auditory Masking Effects on Speech Fluency in Aphasia and Apraxia of Speech

Auditory Feedback Participants will produce sentences while listening to speech-shaped noise at 85 decibels (sound pressure level) to mask ability to hear their own speech. Other Name: Masking Noise Behavioral: Altered Auditory Feedback Participants will produce sentences while listening to their speech shifted up one octave and delayed. Other Name: Delayed and pitch-shifted feedback Neurologically Healthy Participants The neurologically healthy participant group will include 15 adults with no history (...) Name: Masking Noise Behavioral: Altered Auditory Feedback Participants will produce sentences while listening to their speech shifted up one octave and delayed. Other Name: Delayed and pitch-shifted feedback Outcome Measures Go to Primary Outcome Measures : Disfluency duration change with masking noise [ Time Frame: 1 day of the study ] Measured disfluency duration in sentences produced while listening to masking noise compared to speaking in quiet without noise. Secondary Outcome Measures : Speech

2014 Clinical Trials

122. Amino-Terminal Microdeletion within the CNTNAP2 Gene Associated with Variable Expressivity of Speech Delay (PubMed)

Amino-Terminal Microdeletion within the CNTNAP2 Gene Associated with Variable Expressivity of Speech Delay The contactin-associated protein-like 2 (CNTNAP2) gene is highly expressed in the frontal lobe circuits in the developing human brain. Mutations in this gene have been associated with several neurodevelopmental disorders such as autism and specific language impairment. Here we describe a 450 kb deletion within the CNTNAP2 gene that is maternally inherited in two male siblings

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2012 Case Reports in Genetics

123. Effects of delayed auditory feedback on speech kinematics in fluent speakers (PubMed)

Effects of delayed auditory feedback on speech kinematics in fluent speakers The effects of delayed auditory feedback on behavioral responses and speech kinematics were investigated. Participants were 10 men (M age = 22.2 yr., SD = 3.7) and 10 women (M age = 20.5 yr., SD = 2.2). Participants were required to repeat shorter (6 syllables) and longer (11 syllables) non-words in a reading task. Speech errors, lip movement variability, and movement duration of labial trajectories under delayed (...) feedback were compared to effects under gated speech feedback and a control or synchronous auditory feedback condition. Repeated-measures analysis indicated a lower percent of correct productions, higher variability, and slower duration of lip movements in the delayed feedback condition compared to the gated feedback and control conditions. Implications for auditory feedback of movement control in continuous speech and for theories of delayed auditory feedback that attribute a role to movements

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2012 Perceptual and motor skills

124. Speech Delay

Speech Delay Speech Delay Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Speech Delay Speech Delay Aka: Speech Delay , Language Delay (...) From Related Chapters II. Epidemiology : 219% of children ages 2-7 years old in the U.S. III. Diagnosis IV. Causes: Primary Language Disorders Developmental Speech and Language Delay Delayed speech despite normal comprehension, intelligence, hearing, socialization, articulation Most common of the primary language disorders Expect normal speech by school age with parent and therapist intervention Expressive Language Disorder Presents in similar fashion to Developmental Speech and Language Delay

2015 FP Notebook

125. Parent-based Intervention for Language Delayed 2 to 3 Year Olds

Trust Information provided by (Responsible Party): Solent NHS Trust Study Details Study Description Go to Brief Summary: The aim of the study is to evaluate the impact of parent based intervention on the language of 2 to 3 year old children from socially disadvantaged populations with a clinical diagnosis of primary language delay. Condition or disease Intervention/treatment Phase Speech and Language Therapy Other: Standard PBI Other: Enhanced Not Applicable Detailed Description: This project (...) : Interventional (Clinical Trial) Estimated Enrollment : 192 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: A Randomised Controlled Trial of the Effectiveness of Parent-based Models of Speech and Language Therapy Intervention for 2 to 3 Year Old Children With Primary Language Delay in Areas of Social Disadvantage Estimated Study Start Date : October 2017 Estimated Primary Completion Date : March 2020 Estimated

2017 Clinical Trials

126. Exome sequencing identifies a de novo mutation of CTNNB1 gene in a patient mainly presented with retinal detachment, lens and vitreous opacities, microcephaly, and developmental delay: Case report and literature review. (PubMed)

. Recently, de novo, heterozygous, loss-of-function mutations of the CTNNB1 gene were found that partially explain intellectual disability in some patients. Other major clinical symptoms in these patients included microcephaly, abnormal facial features, motor delays, speech impairments, and deformities of the hands and feet. In addition, approximately 75% of these patients had mild visual defects, such as astigmatism, hyperopia, or strabismus PATIENT CONCERNS:: A 15-month-old Chinese boy, presenting (...) Exome sequencing identifies a de novo mutation of CTNNB1 gene in a patient mainly presented with retinal detachment, lens and vitreous opacities, microcephaly, and developmental delay: Case report and literature review. The CTNNB1 (β-catenin) gene is well known for its crucial role in cell adhesion and the Wnt-signaling pathway. Previous studies have shown that gain-of-function mutations in the CTNNB1 gene contribute to the occurrence and development of a variety of carcinomas in humans

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2017 Medicine

127. Early Intervention Therapy for Children With Delayed Development: Enabling Access in India's Rural Communities

intervention program, a detailed care plan will be developed by the rehabilitation professional(s) who will provide the care based on the specific needs of the child. A trained community rehabilitation worker (CRW) will implement the care plan with a focus on the one or more domains where delays were identified (i.e. speech, motor, cognition). The intervention will be delivered either within the child's home (home based rehabilitation) or at an local Early Intervention Parent Participation Centre (EI PPCs (...) , individualized rehabilitation therapy will be provided by a rehabilitation professional with a focus on the one or more domains where delays were identified (i.e. speech, motor, cognition). The intervention will be delivered either as home based rehabilitation or as centre based care. Each child will receive a minimum of one therapy session per week by the CRW and a monthly therapist visit for home based care. In center based care daily therapy will be available by either a CRW or specialist. Other

2017 Clinical Trials

128. Early Intervention for Developmental Delay

a joint assessment by a pediatrician, a rehabilitation doctor, a child psychiatrist, a speech therapist, a physical therapist, an occupational therapist, and a social worker. Once the diagnosis of developmental delay is confirmed, the child will be scheduled for prescribed family-based early intervention in the same hospital. Children (between 2 to 4 years old) who attend the program will be enrolled in this study. Informed consent will be obtained from the children and their primary caregivers after (...) Early Intervention for Developmental Delay Early Intervention for Developmental Delay - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Early Intervention for Developmental Delay The safety and scientific

2017 Clinical Trials

129. Patient With Delayed Development Resulting From De Novo Duplication of 7q36.1-q36.3 and Deletion of 9p24.3 (PubMed)

Patient With Delayed Development Resulting From De Novo Duplication of 7q36.1-q36.3 and Deletion of 9p24.3 Patients with a duplication from 7q36 to the terminus or a deletion of 9p24 have been reported, whereas those harboring both mutations have not. Here, we report a patient with simultaneous de novo 7q36.1-q36.3 duplication and 9p24.3 deletion. A 6-year-old boy presented with speech developmental delay, microcephaly, and dysmorphic features, including a long face and small nose. Chromosome

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2017 Annals of rehabilitation medicine

130. Altered human voice processing in the frontal cortex and a developmental language delay in 3- to 5-year-old children with autism spectrum disorder (PubMed)

magnetoencephalography (MEG). The children with ASD exhibited significantly decreased activation in the left superior temporal gyrus compared with the TD children for the MMF amplitude. If we classified the children with ASD according to the presence of a speech onset delay (ASD - SOD and ASD - NoSOD, respectively) and compared them with the TD children, both ASD groups exhibited decreased activation in the left superior temporal gyrus compared with the TD children. In contrast, the ASD - SOD group exhibited (...) Altered human voice processing in the frontal cortex and a developmental language delay in 3- to 5-year-old children with autism spectrum disorder The inferior frontal and superior temporal areas in the left hemisphere are crucial for human language processing. In the present study, we investigated the magnetic mismatch field (MMF) evoked by voice stimuli in 3- to 5-year-old typically developing (TD) children and children with autism spectrum disorder (ASD) using child-customized

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2017 Scientific reports

131. Delayed dyskinesia and prolonged psychosis in a patient presenting with profound hyponatraemia (PubMed)

Delayed dyskinesia and prolonged psychosis in a patient presenting with profound hyponatraemia A 65-year-old woman was admitted to the emergency unit with a 48 h history of generalised weakness and confusion. On examination, she had mild slurring of speech although there was no other focal neurological deficit. She had profound hyponatraemia (serum sodium level of 100 mmol/L) on admission with the rest of her metabolic parameters being within normal range. Subsequent investigations confirmed (...) the diagnosis of small-cell lung cancer with paraneoplastic syndrome of inappropriate antidiuresis (SIAD). She was monitored closely in high-dependency unit with an attempt to cautiously correct her hyponatraemia to prevent sequelae associated with rapid correction. The patient developed prolonged psychosis (lasting over 2 weeks) and displayed delayed dyskinetic movements, even after a gradual increase in serum sodium levels close to 130 mmol/L. To our knowledge, delayed neurological recovery from profound

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2017 Endocrinology, diabetes & metabolism case reports

132. Characterization of a de novo sSMC 17 detected in a girl with developmental delay and dysmorphic features (PubMed)

Characterization of a de novo sSMC 17 detected in a girl with developmental delay and dysmorphic features The majority of small supernumerary marker chromosome cases arise de novo and their frequency in newborns is 0.04%. We report on a girl with developmental delay and dysmorphic features with a non-mosaic de novo sSMC that originated from the pericentric region of q arm in chromosome 17.The girl presented with developmental delay, speech delay, myopia, mild muscle hypotonia, hypoplasia (...) of orbicular muscle, poor concentration, and hyperactivity. Main dysmorphic features included: round face, microstomia, small chin, down-slanting palpebral fissures and small lobules of both ears. At present, her developmental abilities are still delayed for her chronological age but she is making evident progress with speech. A postnatal array comparative genomic hybridization showed a 2.31 Mb genomic gain indicating microduplication derived from pericentric regions q11.1 and q11.2 of chromosome 17

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2017 Molecular cytogenetics

133. Modulation of auditory-motor learning in response to formant perturbation as a function of delayed auditory feedback (PubMed)

Modulation of auditory-motor learning in response to formant perturbation as a function of delayed auditory feedback The interaction of language production and perception has been substantiated by empirical studies where speakers compensate their speech articulation in response to the manipulated sound of their voice heard in real-time as auditory feedback. A recent study by Max and Maffett [(2015). Neurosci. Lett. 591, 25-29] reported an absence of compensation (i.e., auditory-motor learning (...) ) for frequency-shifted formants when auditory feedback was delayed by 100 ms. In the present study, the effect of auditory feedback delay was studied when only the first formant was manipulated while delaying auditory feedback systematically. In experiment 1, a small yet significant compensation was observed even with 100 ms of auditory delay unlike the past report. This result suggests that the tolerance of feedback delay depends on different types of auditory errors being processed. In experiment 2

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2017 The Journal of the Acoustical Society of America

134. Constant and Variable Time Delays of Synchrony of Facial Expressions in Dyadic Conversations (PubMed)

Constant and Variable Time Delays of Synchrony of Facial Expressions in Dyadic Conversations 29472730 2018 12 17 2018 12 17 1532-7906 52 1 2017 01 Multivariate behavioral research Multivariate Behav Res Constant and Variable Time Delays of Synchrony of Facial Expressions in Dyadic Conversations. 122-123 10.1080/00273171.2016.1265436 Meyer M Joseph MJ University of Virginia, Department of Psychology, 485 McCormick Road, Gilmer Hall, Charlottesville, VA 22903. eng R21 AG041035 AG NIA NIH HHS (...) United States BCS-1030806 National Science Foundation International Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. 2017 01 18 United States Multivariate Behav Res 0046052 0027-3171 IM Emotions Face Facial Expression Factor Analysis, Statistical Humans Image Processing, Computer-Assisted Interpersonal Relations Speech Speech Perception Time Factors Video Recording Conflict of Interest Disclosures: The author signed a form for disclosure of potential

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2017 Multivariate Behavioral Research

135. The Effects of Pitch Shifts on Delay-Induced Changes in Vocal Sequencing in a Songbird (PubMed)

The Effects of Pitch Shifts on Delay-Induced Changes in Vocal Sequencing in a Songbird Like human speech, vocal behavior in songbirds depends critically on auditory feedback. In both humans and songbirds, vocal skills are acquired by a process of imitation whereby current vocal production is compared to an acoustic target. Similarly, performance in adulthood relies strongly on auditory feedback, and online manipulations of auditory signals can dramatically alter acoustic production even after (...) vocalizations have been well learned. Artificially delaying auditory feedback can disrupt both speech and birdsong, and internal delays in auditory feedback have been hypothesized as a cause of vocal dysfluency in persons who stutter. Furthermore, in both song and speech, online shifts of the pitch (fundamental frequency) of auditory feedback lead to compensatory changes in vocal pitch for small perturbations, but larger pitch shifts produce smaller changes in vocal output. Intriguingly, large pitch shifts

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2017 eNeuro

136. Oral Health Characteristics and Dental Rehabilitation of Children with Global Developmental Delay (PubMed)

Oral Health Characteristics and Dental Rehabilitation of Children with Global Developmental Delay Global developmental delay (GDD) is a chronic neurological disturbance which includes defects in one or more developmental domains. The developmental domain can be motor, cognitive, daily activities, speech or language, and social or personal development. The etiology for GDD can be prenatal, perinatal, or postnatal. It can be diagnosed early in childhood as the delay or absence of one or more

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2017 Case reports in dentistry

137. Delayed access to bilateral input alters cortical organization in children with asymmetric hearing (PubMed)

Delayed access to bilateral input alters cortical organization in children with asymmetric hearing Bilateral hearing in early development protects auditory cortices from reorganizing to prefer the better ear. Yet, such protection could be disrupted by mismatched bilateral input in children with asymmetric hearing who require electric stimulation of the auditory nerve from a cochlear implant in their deaf ear and amplified acoustic sound from a hearing aid in their better ear (bimodal hearing (...) ). Cortical responses to bimodal stimulation were measured by electroencephalography in 34 bimodal users and 16 age-matched peers with normal hearing, and compared with the same measures previously reported for 28 age-matched bilateral implant users. Both auditory cortices increasingly favoured the better ear with delay to implanting the deaf ear; the time course mirrored that occurring with delay to bilateral implantation in unilateral implant users. Preference for the implanted ear tended to occur

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2017 NeuroImage : Clinical

138. Delayed brain atrophy after electrical injury. (PubMed)

Delayed brain atrophy after electrical injury. We report a case of delayed brain atrophy after electrical injury. A 12-year-old boy sustained extensive burns by touching a high-voltage power line. The burn area comprised more than 60% TBSA, and he subsequently underwent several surgical procedures. Two months later, he suddenly developed seizures. Initial findings on magnetic resonance imaging showed diffuse cortical damage in the left brain. Two months later, motor aphasia appeared (...) , and a second magnetic resonance imaging scan showed atrophy in the left temporal and frontal lobes. Owing to speech rehabilitation, the patient gradually recovered his capacity for speech. Eight months later, his speech was almost perfect. We believe that because the patient was young, early speech rehabilitation was effective.

2017 Journal of Burn Care & Rehabilitation

139. Clinical Inquiry: How should you evaluate a toddler for speech delay? (PubMed)

Clinical Inquiry: How should you evaluate a toddler for speech delay? 21472154 2011 06 28 2011 04 07 1533-7294 60 4 2011 Apr The Journal of family practice J Fam Pract Clinical inquiries. How should you evaluate a toddler for speech delay? 230-1 Jackson Jo J University of Washington, Seattle, USA. Kornrich Rachel R Safranek Sarah S eng Journal Article Review United States J Fam Pract 7502590 0094-3509 AIM IM Child, Preschool Diagnosis, Differential Evidence-Based Medicine Humans Language

2011 Journal of Family Practice

140. Are sex chromosone abnormalities a factor in speech delay? (PubMed)

Are sex chromosone abnormalities a factor in speech delay? 727806 1979 02 26 2018 11 13 1468-2044 53 10 1978 Oct Archives of disease in childhood Arch. Dis. Child. Are sex chromosone abnormalities a factor in speech delay? 831 Tuncbilek E E Kurultay N N Belgin E E eng Journal Article England Arch Dis Child 0372434 0003-9888 AIM IM Child Child, Preschool Female Humans Male Sex Chromosome Aberrations Speech Disorders genetics 1978 10 1 1978 10 1 0 1 1978 10 1 0 0 ppublish 727806 PMC1545401 Hum

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1978 Archives of Disease in Childhood

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