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Speech Delay

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41. Two-Year Outcomes of a Population-Based Intervention for Preschool Language Delay: An RCT (Full text)

Two-Year Outcomes of a Population-Based Intervention for Preschool Language Delay: An RCT We have previously shown short-term benefits to phonology, letter knowledge, and possibly expressive language from systematically ascertaining language delay at age 4 years followed by the Language for Learning intervention. Here, we report the trial's definitive 6-year outcomes.Randomized trial nested in a population-based ascertainment. Children with language scores >1.25 SD below the mean at age 4 were (...) for intervention families (mean difference AU$4276; 95% CI: $3424 to $5128).Population-based intervention targeting 4-year-old language delay was feasible but did not have lasting impacts on language, possibly reflecting resolution in both groups. Long-term literacy benefits remain possible but must be weighed against its cost.Copyright © 2015 by the American Academy of Pediatrics.

2015 EvidenceUpdates Controlled trial quality: predicted high PubMed abstract

42. Speech Delay

Speech Delay Speech Delay Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Speech Delay Speech Delay Aka: Speech Delay , Language Delay (...) From Related Chapters II. Epidemiology : 219% of children ages 2-7 years old in the U.S. III. Diagnosis IV. Causes: Primary Language Disorders Developmental Speech and Language Delay Delayed speech despite normal comprehension, intelligence, hearing, socialization, articulation Most common of the primary language disorders Expect normal speech by school age with parent and therapist intervention Expressive Language Disorder Presents in similar fashion to Developmental Speech and Language Delay

2018 FP Notebook

43. Early intervention for toddlers with language delays: a randomized controlled trial (Full text)

Early intervention for toddlers with language delays: a randomized controlled trial Early interventions for toddlers with expressive and receptive language delays have not resulted in positive expressive language outcomes. This randomized controlled trial tested the effects on language outcomes of a caregiver-implemented communication intervention targeting toddlers at risk for persistent language delays.Participants included 97 toddlers, who were between 24 and 42 months with language scores (...) at least 1.33 SDs below the normative mean and no other developmental delays, and their caregivers. Toddlers were randomly assigned to the caregiver-implemented intervention or a usual-care control group. Caregivers and children participated in 28 sessions in which caregivers were taught to implement the intervention. The primary outcome was the Preschool Language Scale, Fourth Edition, a broad-based measure of language. Outcome measurement was not blinded.Caregivers in the intervention improved

2015 EvidenceUpdates Controlled trial quality: predicted high PubMed abstract

44. Parent-implemented early language intervention programme for late talkers: parental communicative behaviour change and child language outcomes at 3 and 4 years of age. (Abstract)

, little is known about which strategies parents learn to use after participating in parent programmes and whether this affects their child's language development.To evaluate medium- and long-term effectiveness (1 and 2 years after inclusion) of a low-dosage parent programme in a sample of late talkers (LTs) with an expressive language delay. Specifically, we investigated which strategies the parents learned to use in interaction with their child and which strategies were associated with child language (...) language scores below the mean range. Ongoing monitoring of LTs' language development is necessary in order to make decisions regarding the timing and nature of intervention.© 2019 Royal College of Speech and Language Therapists.

2019 International Journal of Language & Communication Disorders Controlled trial quality: uncertain

45. Internet delivery of intensive speech and language therapy for children with cerebral palsy: a pilot randomised controlled trial. (Full text)

Internet delivery of intensive speech and language therapy for children with cerebral palsy: a pilot randomised controlled trial. To test the feasibility of recruitment, retention, outcome measures and internet delivery of dysarthria therapy for young people with cerebral palsy in a randomised controlled trial.Mixed methods. Single blind pilot randomised controlled trial, with control offered Skype therapy at end of study. Qualitative study of the acceptability of therapy delivery via (...) Skype.Nine speech and language therapy departments in northern England recruited participants to the study. Skype therapy was provided in a university setting.Twenty-two children (14 M, 8 F) with dysarthria and cerebral palsy (mean age 8.8 years (SD 3.2)) agreed to take part. Participants were randomised to dysarthria therapy via Skype (n=11) or treatment as usual (n=11).Children received either usual speech therapy from their local therapist for 6 weeks or dysarthria therapy via Skype from a research

2019 BMJ open Controlled trial quality: uncertain PubMed abstract

46. Speech and language characteristics in individuals with nonsyndromic submucous cleft palate-A systematic review. (Abstract)

Speech and language characteristics in individuals with nonsyndromic submucous cleft palate-A systematic review. Up to 80% of individuals with unrepaired submucous cleft palate (SMCP) experience speech difficulties secondary to velopharyngeal insufficiency. Language delays are reported in the broader cleft lip and/or palate population, suggesting that individuals with SMCP may also be at risk. However, contemporary understanding of this population remains limited as there has been no systematic (...) examination of the literature. This review aims to systematically review and document the speech and language characteristics of individuals with nonsyndromic SMCP and, in addition, to identify factors reported to impact speech and language outcomes.This review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Five databases were comprehensively searched using keywords and indexed headings. Included studies had to report speech or language outcomes of individuals

2019 Child: care, health and development

47. Genome-Wide Sequencing for Unexplained Developmental Delays and Multiple Congenital Anomalies: A Rapid Qualitative Review

Genome-Wide Sequencing for Unexplained Developmental Delays and Multiple Congenital Anomalies: A Rapid Qualitative Review Genome-Wide Sequencing for Unexplained Developmental Delays and Multiple Congenital Anomalies: A Rapid Qualitative Review | CADTH.ca Find the information you need Genome-Wide Sequencing for Unexplained Developmental Delays and Multiple Congenital Anomalies: A Rapid Qualitative Review Genome-Wide Sequencing for Unexplained Developmental Delays and Multiple Congenital (...) Anomalies: A Rapid Qualitative Review Last updated: May 16, 2019 Project Number: RC1098-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical Appraisal Result type: Report Question How have families, and their health care providers, seeking clarity on a personís unexplained developmental delays or multiple congenital anomalies experienced engaging with the processes of whole exome and/or whole genome sequencing as a diagnostic tool? For example, among other things: How

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

48. Natural Language Processing of Clinical Notes on Chronic Diseases: Systematic Review. (Full text)

Natural Language Processing of Clinical Notes on Chronic Diseases: Systematic Review. Novel approaches that complement and go beyond evidence-based medicine are required in the domain of chronic diseases, given the growing incidence of such conditions on the worldwide population. A promising avenue is the secondary use of electronic health records (EHRs), where patient data are analyzed to conduct clinical and translational research. Methods based on machine learning to process EHRs (...) are resulting in improved understanding of patient clinical trajectories and chronic disease risk prediction, creating a unique opportunity to derive previously unknown clinical insights. However, a wealth of clinical histories remains locked behind clinical narratives in free-form text. Consequently, unlocking the full potential of EHR data is contingent on the development of natural language processing (NLP) methods to automatically transform clinical text into structured clinical data that can guide

2020 JMIR medical informatics PubMed abstract

49. Assessment of learning difficulty and cognitive delay

impairment have below-average IQ, at <70. Harris JC. Developmental neuropsychiatry, Volumes 1 and 2. Oxford, UK: Oxford University Press; 1998. The degree of cognitive impairment depends on the underlying disorder and its severity. An IQ of 50 to 70 is classed as mild cognitive impairment. Children with a specific learning difficulty, on the other hand, have difficulties with particular mental tasks but a normal IQ. Examples include difficulties with speech (specific language impairment), reading (...) therapist. The role of the clinical psychologist is to identify the child's cognitive ability (IQ, or age-equivalent developmental level, which can be compared with their chronological age). Speech therapists help assess the child's expressive and receptive (understanding) language abilities and compare these with the overall level of cognitive ability. Some children have a discrepancy between cognitive and language abilities. For example, children with autism sometimes have relatively superior non

2018 BMJ Best Practice

50. Survival differences with immediate versus delayed chemotherapy for asymptomatic incurable metastatic colorectal cancer. (Full text)

August 2018. We did not apply limitations based on language or date of publication. We searched the reference lists of all included studies to identify trials that may not have been identified from the electronic searches.Randomised controlled trials evaluating immediate versus delayed chemotherapy in persons with asymptomatic, metastatic, incurable colorectal cancer.We applied standard methodological procedures, according to the recommendations of Cochrane and Cochrane Colorectal Cancer. Two review (...) Survival differences with immediate versus delayed chemotherapy for asymptomatic incurable metastatic colorectal cancer. For patients with asymptomatic, incurable, metastatic colorectal cancer, palliative, systemic treatment can be started immediately, or can be delayed until disease-related symptoms occur. How the potential survival benefit of starting palliative, systemic treatment immediately after diagnosis weighs up against the potential side effects is currently under debate

2018 Cochrane PubMed abstract

51. Persistent Language Delay Versus Late Language Emergence in Children With Early Cochlear Implantation (Full text)

language emergence (n = 19), late language emergence (n = 22), or persistent language delay (n = 19) on the basis of their test scores at 4.5 and 10.5 years of age. Relative effects of demographic, audiological, linguistic, and academic characteristics on language emergence were determined.Age at CI was associated with normal language emergence but did not differentiate late emergence from persistent delay. Children with persistent delay were more likely to use left-ear implants and older speech (...) processor technology. They experienced higher aided thresholds and lower speech perception scores. Persistent delay was foreshadowed by low morphosyntactic and phonological diversity in preschool. Logistic regression analysis predicted normal language emergence with 84% accuracy and persistent language delay with 74% accuracy.CI characteristics had a strong effect on persistent versus resolving language delay, suggesting that right-ear (or bilateral) devices, technology upgrades, and improved audibility

2016 Journal of speech, language, and hearing research : JSLHR PubMed abstract

52. Fosnetupitant and palonosetron (Akynzeo) - To prevent acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic cancer chemotherapy

Fosnetupitant and palonosetron (Akynzeo) - To prevent acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic cancer chemotherapy Drug Approval Package: Akynzeo (fosnetupitant and palonosetron) Injection U.S. Department of Health and Human Services Search FDA Submit search Drug Approval Package: Akynzeo (fosnetupitant and palonosetron) Injection Company: Helsinn Healthcare SA Application Number: 210493 Approval Date: 04/19/2018 Persons (...) with disabilities having problems accessing the PDF files below may call (301) 796-3634 for assistance. FDA Approval Letter and Labeling (PDF) (PDF) FDA Application Review Files (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) Date created: May 31, 2018 Vision impaired people having problems accessing certain pages of a PDF file may call (301) 796-3634 for assistance. Note: Documents in PDF format require the . Note: If you need help accessing information in different file formats, see . Language Assistance Available

2018 FDA - Drug Approval Package

53. Differentiation of speech delay and global developmental delay in children Using DTI Tractography-Based Connectome (Full text)

), efficiency (measures of global and local integration), cluster coefficient (a measure of local aggregation), and betweeness (a measure of centrality).Compared with typical development, global and local efficiency were significantly reduced in both global developmental delay and speech delay (P < .0001). The nodal strength of the cognitive network is reduced in global developmental delay, whereas the nodal strength of the language network is reduced in speech delay. This finding resulted in a high (...) Differentiation of speech delay and global developmental delay in children Using DTI Tractography-Based Connectome Pure speech delay is a common developmental disorder which, according to some estimates, affects 5%-8% of the population. Speech delay may not only be an isolated condition but also can be part of a broader condition such as global developmental delay. The present study investigated whether diffusion tensor imaging tractography-based connectome can differentiate global

2016 AJNR. American journal of neuroradiology PubMed abstract

54. When does speech sound disorder matter for literacy? The role of disordered speech errors, co-occurring language impairment and family risk of dyslexia. (Full text)

emergent literacy skills, and children with 'disordered' speech errors had poorer word reading skills than children whose speech errors indicated 'delay'. In contrast, the initial severity of SSD was not a significant predictor of reading development. Beyond the domain of speech, the presence of a co-occurring language impairment was strongly predictive of literacy skills and having a family risk of dyslexia predicted additional variance in literacy at both time-points.Early SSD alone has only modest (...) When does speech sound disorder matter for literacy? The role of disordered speech errors, co-occurring language impairment and family risk of dyslexia. This study considers the role of early speech difficulties in literacy development, in the context of additional risk factors.Children were identified with speech sound disorder (SSD) at the age of 3½ years, on the basis of performance on the Diagnostic Evaluation of Articulation and Phonology. Their literacy skills were assessed at the start

2017 Journal of Child Psychology and Psychiatry PubMed abstract

55. Speech, language, hearing delays: Time for early intervention? (Abstract)

Speech, language, hearing delays: Time for early intervention? A wait-and-see approach may not be best for the child exhibiting delayed development. This review--complete with extensive resource lists--can facilitate an expeditious referral.

2015 Journal of Family Practice

56. Screening for Speech and Language Delay and Disorders in Children Aged 5 Years or Younger: US Preventive Services Task Force Recommendation Statement. (Full text)

Screening for Speech and Language Delay and Disorders in Children Aged 5 Years or Younger: US Preventive Services Task Force Recommendation Statement. This report is an update of the US Preventive Services Task Force (USPSTF) 2006 recommendation on screening for speech and language delay in preschool-aged children.The USPSTF reviewed the evidence on screening for speech and language delay and disorders in children aged 5 years or younger, including the accuracy of screening in primary care (...) for speech and language delay and disorders in children aged 5 years or younger (I statement).Copyright © 2015 by the American Academy of Pediatrics.

2015 Pediatrics PubMed abstract

57. Timing of Transcranial Direct Current Stimulation (tDCS) Combined With Speech and Language Therapy (SLT)

in the USA. Aphasia impacts language production and comprehension as well as reading and writing. The ramifications of aphasia extend beyond language impairment to negatively impacting a person's social, vocational, and recreational activities. Currently, the most effective way to treat aphasia is with speech-language therapy (SLT). However, even if SLT is intensive, persons with aphasia are left with residual language delays. Recent research suggests that pairing SLT with transcranial direct current (...) Timing of Transcranial Direct Current Stimulation (tDCS) Combined With Speech and Language Therapy (SLT) Timing of Transcranial Direct Current Stimulation (tDCS) Combined With Speech and Language Therapy (SLT) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100

2018 Clinical Trials

58. Dorsolateral Prefrontal Transcranial Direct Current Stimulation Modulates Language Processing but Does Not Facilitate Overt Second Language Word Production (Full text)

stimulation (anodal-tDCS) over the DLPFC on picture naming and word translation and on event-related potentials (ERPs) and their sources. Twenty-six bilingual participants with "unbalanced" proficiency in two languages were given 20 min of 1.5 mA anodal or sham tDCS (double-blind stimulation design, counterbalanced stimulation order, 1-week intersession delay). The participants then performed the following tasks: verbal and non-verbal fluency during anodal-tDCS stimulation and first and second language (...) (L1 and L2) picture naming and translation [forward (L1 → L2) and backward (L2 → L1)] immediately after stimulation. The electroencephalogram (EEG) was recorded during picture naming and translation. On the behavioral level, anodal-tDCS had an influence on non-verbal fluency but neither on verbal fluency, nor on picture naming and translation. EEG measures revealed significant interactions between Language and Stimulation on picture naming around 380 ms post-stimulus onset and Translation

2018 Frontiers in neuroscience Controlled trial quality: uncertain PubMed abstract

59. Weaker semantic language lateralization associated with better semantic language performance in healthy right‐handed children (Full text)

. Furthermore, less lateralized parietal language was associated with better out-of-scanner verbal memory across learning, short- and long-delay trials. In contrast, we did not find any relationship between temporal lobe language laterality and verbal performance.This study suggests that semantic language performance is better with some involvement of the nondominant hemisphere.© 2018 The Authors. Brain and Behavior published by Wiley Periodicals, Inc. (...) Weaker semantic language lateralization associated with better semantic language performance in healthy right‐handed children The relationship between language abilities and language lateralization in the developing brain is important for our understanding of the neural architecture of language development.We investigated 35 right-handed children and adolescents aged 7-16 years with a functional magnetic resonance imaging language paradigm and a comprehensive language and verbal memory

2018 Brain and behavior PubMed abstract

60. A Speech Recognition-based Solution for the Automatic Detection of Mild Cognitive Impairment from Spontaneous Speech (Full text)

A Speech Recognition-based Solution for the Automatic Detection of Mild Cognitive Impairment from Spontaneous Speech Even today the reliable diagnosis of the prodromal stages of Alzheimer's disease (AD) remains a great challenge. Our research focuses on the earliest detectable indicators of cognitive decline in mild cognitive impairment (MCI). Since the presence of language impairment has been reported even in the mild stage of AD, the aim of this study is to develop a sensitive (...) neuropsychological screening method which is based on the analysis of spontaneous speech production during performing a memory task. In the future, this can form the basis of an Internet-based interactive screening software for the recognition of MCI.Participants were 38 healthy controls and 48 clinically diagnosed MCI patients. The provoked spontaneous speech by asking the patients to recall the content of 2 short black and white films (one direct, one delayed), and by answering one question. Acoustic

2018 Current Alzheimer research PubMed abstract

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