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Speech Delay

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1. One-Year Language Outcomes in Toddlers With Language Delays: An RCT Follow-up (Full text)

One-Year Language Outcomes in Toddlers With Language Delays: An RCT Follow-up The current study is a 1-year follow-up analysis of data from a randomized controlled trial of Enhanced Milieu Teaching (EMT) for toddlers with language delays. Outcomes and predictors of child language and parent intervention implementation were examined 6 and 12 months after the end of the intervention.Toddlers with language delays were recruited from the community, and 97 toddlers and parents were randomly assigned (...) to receive usual community treatments or a 3-month EMT intervention with parent training. Multiple regression analyses were used to estimate the differences between groups at the 6- and 12-month follow-up periods. A subgroup of participants with receptive and expressive language delays was used in a post hoc moderator analysis of treatment outcomes.Children in the treatment arm did not differ from children in the control arm at 6- and 12-month follow-ups. However, post hoc analyses revealed that children

2018 EvidenceUpdates PubMed abstract

2. Preliminary evaluation of a low-intensity parent training program on speech-language stimulation for children with language delay. (Abstract)

Preliminary evaluation of a low-intensity parent training program on speech-language stimulation for children with language delay. The study assessed the outcome of a low-intensity parent training program for improving parent's language input to children with language delay.Nine parents and their children aged between 12 months to 24 months, exhibiting delay in language development, participated in a brief training program over three sessions. Training comprised of inputs on speech-language (...) development, play development and speech-language stimulation strategies, supported by a manual. Effect of the training program on parent's language behaviour was evaluated through observations of parent-child interaction recorded before training and six-weeks and 10-weeks post training. Measures including, different functions served by verbalizations of parents and their nonverbal affective behaviours, were analysed.Parents' verbalizations increased significantly from baseline to the two follow-up

2019 International Journal of Pediatric Otorhinolaryngology

3. Screening for speech and language delays and disorders in children age 5 years or younger: a systematic review for the U.S. Preventive Services Task Force

Screening for speech and language delays and disorders in children age 5 years or younger: a systematic review for the U.S. Preventive Services Task Force Screening for speech and language delays and disorders in children age 5 years or younger: a systematic review for the U.S. Preventive Services Task Force Screening for speech and language delays and disorders in children age 5 years or younger: a systematic review for the U.S. Preventive Services Task Force To evaluate the evidence (...) on screening and treating children for speech and language delays or disorders for the U.S. Preventive Services Task Force (USPSTF) Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation To evaluate the evidence on screening and treating children for speech and language delays or disorders for the U.S. Preventive Services Task Force (USPSTF). Screening

2015 Health Technology Assessment (HTA) Database.

4. Speech and Language Delay and Disorders in Children Age 5 and Younger: Screening

Speech and Language Delay and Disorders in Children Age 5 and Younger: Screening Recommendation | United States Preventive Services Taskforce Toggle navigation Main navigation Main navigation Recommendation Children aged 5 years or younger The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for speech and language delay and disorders in children aged 5 years or younger. I View the Clinical Summary in Population Asymptomatic (...) children aged ≤5 years whose parents or clinicians do not have specific concerns about their speech, language, hearing, or development Recommendation No recommendation. Grade: I statement (insufficient evidence) Risk Assessment Risk factors that have been reported to be associated with speech and language delay and disorders include male sex, family history of speech and language impairment, low parental education level, and perinatal risk factors (e.g., prematurity, low birth weight, and birth

2015 U.S. Preventive Services Task Force

5. The value of diffusion tensor imaging for differentiating autism spectrum disorder with language delay from developmental language disorder among toddlers. (Full text)

The value of diffusion tensor imaging for differentiating autism spectrum disorder with language delay from developmental language disorder among toddlers. Impaired language function is frequently observed as an initial sign in people with autism spectrum disorder (ASD). However, clinically, the early stages of ASD are difficult to distinguish from those of developmental language disorder (DLD).To evaluate the ability of diffusion tensor imaging (DTI) parameters for language-related white (...) matter tracts (arcuate fasciculus) to differentiate ASD from DLD among toddlers.We included 16 ASD toddlers with language delay and 18 DLD toddlers in this study. Magnetic resonance imaging sequences included T2-weighted imaging (T2WI), T1 3-dimensional magnetization-prepared rapid acquisition gradient-echo (3D MP-RAGE), and DTI. Tractography was performed using Neuro 3D in the Siemens Syngo Workstation, and fractional anisotropy (FA), average fiber length (AFL), tract volume (TV), and number

2019 Medicine PubMed abstract

6. Predictors of longer-term development of expressive language in two independent longitudinal cohorts of language-delayed preschoolers with Autism Spectrum Disorder. (Abstract)

Predictors of longer-term development of expressive language in two independent longitudinal cohorts of language-delayed preschoolers with Autism Spectrum Disorder. Studies estimate that 30% of individuals with autism are minimally verbal. Understanding what factors predict longer-term expressive development in children with language delays is critical to inform identification and treatment of those at-risk for persistent language impairments. The present study examined predictors of expressive (...) language development in language-delayed preschoolers followed through later school-age and young adulthood.Children using single words or less on the Autism Diagnostic Observation Schedule (ADOS) at approximately 3 years old were drawn from the Early Diagnosis (EDX) and Pathways in ASD longitudinal cohorts. Age-3 predictors of Age-19 ADOS language level were identified using Classification and Regression Trees (CART) in the EDX sample. Linear mixed models examined the effects of CART-identified

2019 Journal of Child Psychology and Psychiatry

7. Screening Tools Compared to Parental Concern for Identifying Speech and Language Delays in Preschool Children: A Review of the Diagnostic Accuracy

Screening Tools Compared to Parental Concern for Identifying Speech and Language Delays in Preschool Children: A Review of the Diagnostic Accuracy Screening Tools Compared With Parental Concern for Identifying Speech and Language Delays in Preschool Children: A Review Context Because the acquisition of speech and language skills is fundamental to a child’s development, early identification of delays in this area is important. Screening for speech and language delays may allow more children (...) to have access to intervention services or assistance at an age when they are likely to derive the greatest benefit. Technology Screening methods used to identify young children at risk of speech and language delays include direct interaction with the child, parent-completed screening instruments such as standardized tests and questionnaires, and expressions of concern from parents regarding their children’s communication skills. Children who have been identified as being at risk can then undergo more

2013 Canadian Agency for Drugs and Technologies in Health - Rapid Review

8. Screening tools compared to parental concern for identifying speech and language delays in preschool children: a review of the diagnostic accuracy

Screening tools compared to parental concern for identifying speech and language delays in preschool children: a review of the diagnostic accuracy Screening tools compared to parental concern for identifying speech and language delays in preschool children: a review of the diagnostic accuracy Screening tools compared to parental concern for identifying speech and language delays in preschool children: a review of the diagnostic accuracy CADTH Record Status This is a bibliographic record (...) of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation CADTH. Screening tools compared to parental concern for identifying speech and language delays in preschool children: a review of the diagnostic accuracy. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH). Rapid Response - Summary with Critical Appraisal. 2013 Authors' conclusions No health technology assessments, systematic

2014 Health Technology Assessment (HTA) Database.

9. A Diagnostic Marker to Discriminate Childhood Apraxia of Speech From Speech Delay: III. Theoretical Coherence of the Pause Marker with Speech Processing Deficits in Childhood Apraxia of Speech (Full text)

A Diagnostic Marker to Discriminate Childhood Apraxia of Speech From Speech Delay: III. Theoretical Coherence of the Pause Marker with Speech Processing Deficits in Childhood Apraxia of Speech Previous articles in this supplement described rationale for and development of the pause marker (PM), a diagnostic marker of childhood apraxia of speech (CAS), and studies supporting its validity and reliability. The present article assesses the theoretical coherence of the PM with speech processing (...) deficits in CAS.PM and other scores were obtained for 264 participants in 6 groups: CAS in idiopathic, neurogenetic, and complex neurodevelopmental disorders; adult-onset apraxia of speech (AAS) consequent to stroke and primary progressive apraxia of speech; and idiopathic speech delay.Participants with CAS and AAS had significantly lower scores than typically speaking reference participants and speech delay controls on measures posited to assess representational and transcoding processes

2017 Journal of speech, language, and hearing research : JSLHR PubMed abstract

10. Comparison of Language Features, Autism Spectrum Symptoms in Children Diagnosed with Autism Spectrum Disorder, Developmental Language Delay, and Healthy Controls (Full text)

Comparison of Language Features, Autism Spectrum Symptoms in Children Diagnosed with Autism Spectrum Disorder, Developmental Language Delay, and Healthy Controls Language and communication is very important in social, emotional, and cognitive development of children. Delay in language is the first complaint for children diagnosed with autism spectrum disorder (ASD) or developmental language delay (DLD). In this study it is aimed to evaluate and compare language profiles and autistic symptoms (...) between children diagnosed with ASD, DLD, and healthy controls.Twenty-six children who are diagnosed with ASD, 43 children who are diagnosed with DLD, and 47 healthy controls are included to study; and all children are in the age of 48-72 months. Test of Early Language Development was used to evaluate language profiles, and autism spectrum symptoms were evaluated with social communication questionnaire (SCQ).The sociodemographic features of groups were similar. The statistical significant differences

2018 Archives of Neuropsychiatry PubMed abstract

11. Effectiveness of Intervention in Children with Primary Speech and Language Delays/Disorders: A Meta-analysis of RCTs

Effectiveness of Intervention in Children with Primary Speech and Language Delays/Disorders: A Meta-analysis of RCTs Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated (...) by Jablonski scale; continuous; Jablonski score. ">Data to be extracted: secondary outcome(s) Example: 1st author, year of publication, language, journal. ">Data to be extracted: other as well as a to meta-analysis of pre-clinical studies are available. Example: A meta‐analysis will be performed for all outcome measures reported in 10 or more articles. For subgroup analysis a minimum of 8 studies per subgroup is required. If meta‐analysis is not possible, data will be reported through a descriptive summary

2020 PROSPERO

12. Among children with chronic otitis media or hearing problems documented in childhood, does immediate hearing or speech language intervention compared to delayed or no intervention, improve language outcomes?

Among children with chronic otitis media or hearing problems documented in childhood, does immediate hearing or speech language intervention compared to delayed or no intervention, improve language outcomes? Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears (...) be recalculated from mg/dL); Renal histological damage as assessed by Jablonski scale; continuous; Jablonski score. ">Data to be extracted: secondary outcome(s) Example: 1st author, year of publication, language, journal. ">Data to be extracted: other as well as a to meta-analysis of pre-clinical studies are available. Example: A meta‐analysis will be performed for all outcome measures reported in 10 or more articles. For subgroup analysis a minimum of 8 studies per subgroup is required. If meta‐analysis

2019 PROSPERO

13. Subcortical Brain and Behavior Phenotypes Differentiate Infants with Autism versus Language Delay (Full text)

Subcortical Brain and Behavior Phenotypes Differentiate Infants with Autism versus Language Delay Younger siblings of children with autism spectrum disorder (ASD) are themselves at increased risk for ASD and other developmental concerns. It is unclear if infants who display developmental concerns, but are unaffected by ASD, share similar or dissimilar behavioral and brain phenotypes to infants with ASD. Most individuals with ASD exhibit heterogeneous difficulties with language (...) , and their receptive-expressive language profiles are often atypical. Yet, little is known about the neurobiology that contributes to these language difficulties.In this study, we used behavioral assessments and structural magnetic resonance imaging to investigate early brain structures and associations with later language skills. High-risk infants who were later diagnosed with ASD (n = 86) were compared with high-risk infants who showed signs of early language delay (n = 41) as well as with high- and low-risk

2017 Biological psychiatry. Cognitive neuroscience and neuroimaging PubMed abstract

14. Four delays of child mortality in Rwanda: a mixed methods analysis of verbal social autopsies. (Full text)

Four delays of child mortality in Rwanda: a mixed methods analysis of verbal social autopsies. We sought to understand healthcare-seeking patterns and delays in obtaining effective treatment for rural Rwandan children aged 1-5 years by analysing verbal and social autopsies (VSA). Factors in the home, related to transport and to quality of care in the formal health sector (FHS) were thought to contribute to delays.We collected quantitative and qualitative cross-sectional data using the validated (...) 2012 WHO VSA tool. Descriptive statistics were performed. We inductively and deductively coded narratives using the three delays model, conducted thematic content analysis and used convergent mixed methods to synthesise findings.The study took place in the catchment areas of two rural district hospitals in Rwanda-Kirehe and Southern Kayonza. Participants were caregivers of children aged 1-5 years who died in our study area between March 2013 and February 2014.We analysed 77 VSAs. Although 74

2019 BMJ open PubMed abstract

15. A Diagnostic Marker to Discriminate Childhood Apraxia of Speech From Speech Delay: Introduction (Full text)

A Diagnostic Marker to Discriminate Childhood Apraxia of Speech From Speech Delay: Introduction The goal of this article is to introduce the pause marker (PM), a single-sign diagnostic marker proposed to discriminate early or persistent childhood apraxia of speech (CAS) from speech delay.

2017 Journal of speech, language, and hearing research : JSLHR PubMed abstract

16. A Diagnostic Marker to Discriminate Childhood Apraxia of Speech From Speech Delay: I. Development and Description of the Pause Marker (Full text)

A Diagnostic Marker to Discriminate Childhood Apraxia of Speech From Speech Delay: I. Development and Description of the Pause Marker The goal of this article (PM I) is to describe the rationale for and development of the Pause Marker (PM), a single-sign diagnostic marker proposed to discriminate early or persistent childhood apraxia of speech from speech delay.The authors describe and prioritize 7 criteria with which to evaluate the research and clinical utility of a diagnostic marker (...) and scoring information, and citations to papers and technical reports that include audio exemplars of the PM and reference data used to standardize PM scores are provided.The PM described here is an acoustic-aided perceptual sign that quantifies one aspect of speech precision in the linguistic domain of phrasing. This diagnostic marker can be used to discriminate early or persistent childhood apraxia of speech from speech delay.

2017 Journal of speech, language, and hearing research : JSLHR PubMed abstract

17. A Diagnostic Marker to Discriminate Childhood Apraxia of Speech From Speech Delay: II. Validity Studies of the Pause Marker (Full text)

A Diagnostic Marker to Discriminate Childhood Apraxia of Speech From Speech Delay: II. Validity Studies of the Pause Marker The purpose of this 2nd article in this supplement is to report validity support findings for the Pause Marker (PM), a proposed single-sign diagnostic marker of childhood apraxia of speech (CAS).PM scores and additional perceptual and acoustic measures were obtained from 296 participants in cohorts with idiopathic and neurogenetic CAS, adult-onset apraxia of speech (...) and primary progressive apraxia of speech, and idiopathic speech delay.Adjusted for questionable specificity disagreements with a pediatric Mayo Clinic diagnostic standard, the estimated sensitivity and specificity, respectively, of the PM were 86.8% and 100% for the CAS cohort, yielding positive and negative likelihood ratios of 56.45 (95% confidence interval [CI]: [1.15, 2763.31]) and 0.13 (95% CI [0.06, 0.30]). Specificity of the PM for 4 cohorts totaling 205 participants with speech delay was 98.5

2017 Journal of speech, language, and hearing research : JSLHR PubMed abstract

18. A Diagnostic Marker to Discriminate Childhood Apraxia of Speech From Speech Delay: IV. The Pause Marker Index (Full text)

A Diagnostic Marker to Discriminate Childhood Apraxia of Speech From Speech Delay: IV. The Pause Marker Index Three previous articles provided rationale, methods, and several forms of validity support for a diagnostic marker of childhood apraxia of speech (CAS), termed the pause marker (PM). Goals of the present article were to assess the validity and stability of the PM Index (PMI) to scale CAS severity.PM scores and speech, prosody, and voice precision-stability data were obtained (...) for participants with CAS in idiopathic, neurogenetic, and complex neurodevelopmental disorders; adult-onset apraxia of speech consequent to stroke and primary progressive apraxia; and idiopathic speech delay. Three studies were completed including criterion and concurrent validity studies of the PMI and a temporal stability study of the PMI using retrospective case studies.PM scores were significantly correlated with other signs of CAS precision and stability. The best fit of the distribution of PM scores

2017 Journal of speech, language, and hearing research : JSLHR PubMed abstract

19. Typical versus delayed speech onset influences verbal reporting of autistic interests (Full text)

Typical versus delayed speech onset influences verbal reporting of autistic interests The distinction between autism and Asperger syndrome has been abandoned in the DSM-5. However, this clinical categorization largely overlaps with the presence or absence of a speech onset delay which is associated with clinical, cognitive, and neural differences. It is unknown whether these different speech development pathways and associated cognitive differences are involved in the heterogeneity (...) of the restricted interests that characterize autistic adults.This study tested the hypothesis that speech onset delay, or conversely, early mastery of speech, orients the nature and verbal reporting of adult autistic interests. The occurrence of a priori defined descriptors for perceptual and thematic dimensions were determined, as well as the perceived function and benefits, in the response of autistic people to a semi-structured interview on their intense interests. The number of words, grammatical

2017 Molecular autism PubMed abstract

20. 18q22.1-qter deletion and 4p16.3 microduplication in a boy with speech delay and mental retardation: case report and review of the literature (Full text)

18q22.1-qter deletion and 4p16.3 microduplication in a boy with speech delay and mental retardation: case report and review of the literature Deletions involving the long arm of chromosome 18 have been associated with a highly variable phenotypic spectrum that is related to the extent of the deleted region. Duplications in chromosomal region 4p16.3 have also been shown to cause 4p16.3 microduplication syndrome. Most reported patients of trisomy 4p16.3 have more duplications, including the Wolf (...) -Hirschhorn critical region (WHSCR). Here, we present a patient with speech delay and mental retardation caused by a deletion of 18q (18q22.1-qter) and terminal microduplication of 4p (4p16.3-pter) distal to WHSCR.The patient was a 23-month-old boy with moderate growth retardation, severe speech delay, mental retardation, and dysmorphic features. Single nucleotide polymorphism (SNP) array analysis confirmed an 11.2-Mb terminal deletion at 18q22.1 and revealed a 1.8-Mb terminal duplication of 4p16.3. Our

2018 Molecular cytogenetics PubMed abstract

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