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Speckled Lentiginous Nevus

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1. Speckled lentiginous nevus: understanding the process of development and regression. (PubMed)

Speckled lentiginous nevus: understanding the process of development and regression. 29315489 2018 06 13 1365-2133 178 6 2018 Jun The British journal of dermatology Br. J. Dermatol. Speckled lentiginous naevus: understanding the process of development and regression. 1447-1448 10.1111/bjd.16319 Iwatsuki K K http://orcid.org/0000-0003-4666-3179 Department of Dermatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1, Shikata-cho, Kita-ku, Okayama

2018 British Journal of Dermatology

2. Speckled Lentiginous Nevus

Speckled Lentiginous Nevus Speckled Lentiginous Nevus Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Speckled Lentiginous Nevus (...) Speckled Lentiginous Nevus Aka: Speckled Lentiginous Nevus , Nevus Spilus II. Pathophysiology Variant of III. Signs less round to irregularly shaped brown nevus Larger nevus contains 1-3 mm dots of dark brown pigmentation (may be elevated) Diameter ranges from 1-20 cm IV. Management Malignant transformation is uncommon but can occur Size of lesion directs management - follow the same protocols for based on size below Observe and biopsy or excise lesions if atypical V. Reference Habif (2003) Clinical

2018 FP Notebook

3. Speckled Lentiginous Nevus (Follow-up)

Speckled Lentiginous Nevus (Follow-up) Speckled Lentiginous Nevus Treatment & Management: Medical Care, Surgical Care, Consultations Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA2MTk5MC10cmVhdG1lbnQ (...) = processing > Speckled Lentiginous Nevus Treatment & Management Updated: Apr 07, 2017 Author: Rossitza Lazova, MD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Speckled Lentiginous Nevus Treatment Medical Care Photography and observation are the best clinical approaches for assessing the development of atypical features or the transformation to cutaneous melanoma. Speckled lentiginous nevi are evaluated and treated with the same level of concern as would be warranted

2014 eMedicine.com

4. Speckled Lentiginous Nevus (Treatment)

Speckled Lentiginous Nevus (Treatment) Speckled Lentiginous Nevus Treatment & Management: Medical Care, Surgical Care, Consultations Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA2MTk5MC10cmVhdG1lbnQ (...) = processing > Speckled Lentiginous Nevus Treatment & Management Updated: Apr 07, 2017 Author: Rossitza Lazova, MD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Speckled Lentiginous Nevus Treatment Medical Care Photography and observation are the best clinical approaches for assessing the development of atypical features or the transformation to cutaneous melanoma. Speckled lentiginous nevi are evaluated and treated with the same level of concern as would be warranted

2014 eMedicine.com

5. Speckled Lentiginous Nevus (Overview)

Speckled Lentiginous Nevus (Overview) Speckled Lentiginous Nevus: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA2MTk5MC1vdmVydmlldw== processing > Speckled Lentiginous (...) Nevus Updated: Apr 07, 2017 Author: Rossitza Lazova, MD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Speckled Lentiginous Nevus Overview Background Speckled lentiginous nevus is a patch of hyperpigmentation that can be seen on any area of the body. This patch contains a variable number of darkly pigmented macules and papules. Some authorities believe that speckled lentiginous nevus is a subtype of congenital melanocytic nevus. [ , , ] Next: Pathophysiology

2014 eMedicine.com

6. Speckled Lentiginous Nevus (Diagnosis)

Speckled Lentiginous Nevus (Diagnosis) Speckled Lentiginous Nevus: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA2MTk5MC1vdmVydmlldw== processing > Speckled (...) Lentiginous Nevus Updated: Apr 07, 2017 Author: Rossitza Lazova, MD; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Speckled Lentiginous Nevus Overview Background Speckled lentiginous nevus is a patch of hyperpigmentation that can be seen on any area of the body. This patch contains a variable number of darkly pigmented macules and papules. Some authorities believe that speckled lentiginous nevus is a subtype of congenital melanocytic nevus. [ , , ] Next

2014 eMedicine.com

7. Congenital Melanocytic Nevus Admixed with Speckled Lentiginous Nevus (PubMed)

Congenital Melanocytic Nevus Admixed with Speckled Lentiginous Nevus 23716838 2013 05 30 2018 11 13 1998-3611 58 2 2013 Mar Indian journal of dermatology Indian J Dermatol Congenital melanocytic nevus admixed with speckled lentiginous nevus. 161 10.4103/0019-5154.108091 Jeong Nam-Ji NJ Department of Dermatology, School of Medicine, Chungnam National University, Daejeon, Korea. E-mail: im1177@hanmail.net. Park Seung-Bae SB Lee Young Y Seo Young-Joon YJ Lee Jeung-Hoon JH Im Myung M eng Journal

Full Text available with Trip Pro

2013 Indian journal of dermatology

8. Speckled Lentiginous Nevus

Speckled Lentiginous Nevus Speckled Lentiginous Nevus Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Speckled Lentiginous Nevus (...) Speckled Lentiginous Nevus Aka: Speckled Lentiginous Nevus , Nevus Spilus II. Pathophysiology Variant of III. Signs less round to irregularly shaped brown nevus Larger nevus contains 1-3 mm dots of dark brown pigmentation (may be elevated) Diameter ranges from 1-20 cm IV. Management Malignant transformation is uncommon but can occur Size of lesion directs management - follow the same protocols for based on size below Observe and biopsy or excise lesions if atypical V. Reference Habif (2003) Clinical

2015 FP Notebook

9. Congenital Melanocytic Nevus

centimeters to involving an entire region of the body is variably present Typically with uniform pigmentation V. Types: Speckled Lentiginous Nevus (Nevus Spilus) Variant of Congenital Nevi less round to irregularly shaped brown nevus Larger nevus contains 1-3 mm dots of dark brown pigmentation (may be elevated) Diameter ranges from 1-20 cm Malignant transformation is uncommon but can occur Size of lesion directs management - follow the same protocols for Congenital Nevi based on size below Observe (...) Congenital Melanocytic Nevus Congenital Melanocytic Nevus Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Congenital Melanocytic Nevus

2018 FP Notebook

10. More on Speckled Lentiginous Nevus Syndrome. (PubMed)

More on Speckled Lentiginous Nevus Syndrome. 21071924 2011 04 20 2010 12 23 1421-9832 221 4 2010 Dermatology (Basel, Switzerland) Dermatology (Basel) More on speckled lentiginous nevus syndrome. 324-5 10.1159/000321473 Torchia Daniele D eng Case Reports Letter 2010 11 11 Switzerland Dermatology 9203244 1018-8665 IM Adolescent Adult Child Female Humans Hyperhidrosis diagnosis Male Musculoskeletal Abnormalities diagnosis Nevus, Pigmented diagnosis Paresthesia diagnosis Skin Neoplasms diagnosis

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2010 Dermatology

11. Epidermal Nevus Syndrome (Overview)

) congenital hemidysplasia with ichthyosiform nevus and limb defect, (3) phakomatosis pigmentokeratotica, (4) sebaceous nevus, (5) Becker nevus, and (6) nevus comedonicus [ ] syndromes. Phacomatosis pigmentokeratotica is characterized by the presence of multiple organoid nevi with sebaceous differentiation, a speckled lentiginous nevus, and skeletal and neurologic abnormalities. [ ] It may or may not be associated with extracutaneous involvement. One patient with it developed basal cell carcinoma (...) Epidermal Nevus Syndrome (Overview) Epidermal Nevus Syndrome: Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTExNzUwNi1vdmVydmlldw== processing > Epidermal Nevus Syndrome

2014 eMedicine.com

12. Epidermal Nevus Syndrome (Diagnosis)

) congenital hemidysplasia with ichthyosiform nevus and limb defect, (3) phakomatosis pigmentokeratotica, (4) sebaceous nevus, (5) Becker nevus, and (6) nevus comedonicus [ ] syndromes. Phacomatosis pigmentokeratotica is characterized by the presence of multiple organoid nevi with sebaceous differentiation, a speckled lentiginous nevus, and skeletal and neurologic abnormalities. [ ] It may or may not be associated with extracutaneous involvement. One patient with it developed basal cell carcinoma (...) Epidermal Nevus Syndrome (Diagnosis) Epidermal Nevus Syndrome: Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTExNzUwNi1vdmVydmlldw== processing > Epidermal Nevus Syndrome

2014 eMedicine.com

13. Congenital Melanocytic Nevus

centimeters to involving an entire region of the body is variably present Typically with uniform pigmentation V. Types: Speckled Lentiginous Nevus (Nevus Spilus) Variant of Congenital Nevi less round to irregularly shaped brown nevus Larger nevus contains 1-3 mm dots of dark brown pigmentation (may be elevated) Diameter ranges from 1-20 cm Malignant transformation is uncommon but can occur Size of lesion directs management - follow the same protocols for Congenital Nevi based on size below Observe (...) Congenital Melanocytic Nevus Congenital Melanocytic Nevus Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Congenital Melanocytic Nevus

2015 FP Notebook

14. Phacomatosis pigmentokeratotica or the Schimmelpenning‐Feuerstein‐Mims syndrome? (PubMed)

Phacomatosis pigmentokeratotica or the Schimmelpenning‐Feuerstein‐Mims syndrome? Cutaneous symptoms in some patients with clinical picture of Schimmelpenning-Feuerstein-Mims syndrome can include a speckled lentiginous nevus, also known as nevus spilus. Recent investigations show that somatic heterozygous HRAS mutations are present in the sebaceous and speckled lentiginous nevus tissues of patients with combination of two nevi.

Full Text available with Trip Pro

2016 Clinical Case Reports

15. Skin, Benign Skin Lesions

back acne. Macular benign skin lesions: Seborrheic keratoses of back and trunk. Macular benign skin lesions: Seborrheic keratoses of the face. Macular benign skin lesion: Nevus sebaceous of Jadassohn. Subepidermal lesion: Keratinous cyst (epidermal inclusion cyst). Subepidermal benign lesion: Lipoma of posterior neck. Benign pigmented lesion: Dermatosis papulosa nigra. Psoriasis. Necrobiosis lipoidica diabeticorum. Pyoderma gangrenosum. Next: Defining the Lesion The following 3 general types (...) between the two groups. [ ] See also and . Nevus sebaceus of Jadassohn Nevus sebaceus of Jadassohn is a congenital, yellowish plaque seen on the head and neck. While this lesion often is included in tumors of the skin adnexum, it is actually an epithelial nevus. On histopathology, nevus sebaceus of Jadassohn, or verrucous epidermal nevi (some consider a variant), has a papillomatosis appearance with acanthosis, sebaceous hyperplasia and often absent hair follicles. The lesion tends to enlarge

2014 eMedicine Surgery

16. Dermatologic Manifestations of Gastrointestinal Disease (Diagnosis)

Upper GI cancer Peutz-Jeghers syndrome Diffuse macular GI polyps GI cancer Cronkhite-Canada Diffuse Hepatomegaly Cirrhosis Hepatocellular carcinoma Hemochromatosis Plaques, acral Hepatitis Necrolytic acral erythema Lichenoid papules/plaques Hepatitis Lichen planus Hepatomegaly [ ] Hepatic lesions Sarcoidosis Papules that heal with atrophic scars Perforation Malignant atrophic papulosis [ ] Vascular malformation GI bleeding Blue rubber bleb nevus syndrome Ulcers with undermined borders Malabsorption (...) with malabsorption eventually may lead to iron or folate-deficient anemia states. Therapy involves the adoption of a gluten-free diet, with avoidance of foods such as wheat, barley, and rye. The initiation of therapy with dapsone or sulfapyridine results in a dramatic improvement in both GI and dermatologic symptoms; a prompt improvement following therapy can confirm the diagnosis. Blue rubber bleb nevus syndrome This is characterized by the combination of cutaneous vascular malformations and GI bleeding due

2014 eMedicine.com

17. Laser Treatment of Benign Pigmented Lesions (Overview)

lesions. A typical treatment response includes purpura lasting 5-7 days, followed by subsequent sloughing of the treated lesion at 7-14 days. The underlying new skin is pink for 2-3 days but fades to normal skin color with rare textural changes or scarring. In another study, 25 patients with solar lentigines showed excellent laser-induced clearing after 1-2 treatments. Fourteen patients with café au lait macules showed complete clearing after 3-6 treatments. Two patients with nevus spilus and 2 (...) clearance, briefer pulse widths and treatment without cryogen cooling both, independently, decreased the fluence threshold. In 2001, Suh et al [ ] reported 71 Korean adult patients with superficial pigmented lesions (lentigines and solar lentigines) who demonstrated a very good response rate to multiple Q-switched Nd:YAG laser treatments. In 2003, Downs et al [ ] noted that the combination of the Q-switched Nd:YAG laser for café au lait spots, Becker nevi, speckled nevi, and congenital melanocytic nevi

2014 eMedicine.com

18. Dermatologic Manifestations of Gastrointestinal Disease (Overview)

Upper GI cancer Peutz-Jeghers syndrome Diffuse macular GI polyps GI cancer Cronkhite-Canada Diffuse Hepatomegaly Cirrhosis Hepatocellular carcinoma Hemochromatosis Plaques, acral Hepatitis Necrolytic acral erythema Lichenoid papules/plaques Hepatitis Lichen planus Hepatomegaly [ ] Hepatic lesions Sarcoidosis Papules that heal with atrophic scars Perforation Malignant atrophic papulosis [ ] Vascular malformation GI bleeding Blue rubber bleb nevus syndrome Ulcers with undermined borders Malabsorption (...) with malabsorption eventually may lead to iron or folate-deficient anemia states. Therapy involves the adoption of a gluten-free diet, with avoidance of foods such as wheat, barley, and rye. The initiation of therapy with dapsone or sulfapyridine results in a dramatic improvement in both GI and dermatologic symptoms; a prompt improvement following therapy can confirm the diagnosis. Blue rubber bleb nevus syndrome This is characterized by the combination of cutaneous vascular malformations and GI bleeding due

2014 eMedicine.com

19. Dermatologic Manifestations of Gastrointestinal Disease (Treatment)

Upper GI cancer Peutz-Jeghers syndrome Diffuse macular GI polyps GI cancer Cronkhite-Canada Diffuse Hepatomegaly Cirrhosis Hepatocellular carcinoma Hemochromatosis Plaques, acral Hepatitis Necrolytic acral erythema Lichenoid papules/plaques Hepatitis Lichen planus Hepatomegaly [ ] Hepatic lesions Sarcoidosis Papules that heal with atrophic scars Perforation Malignant atrophic papulosis [ ] Vascular malformation GI bleeding Blue rubber bleb nevus syndrome Ulcers with undermined borders Malabsorption (...) with malabsorption eventually may lead to iron or folate-deficient anemia states. Therapy involves the adoption of a gluten-free diet, with avoidance of foods such as wheat, barley, and rye. The initiation of therapy with dapsone or sulfapyridine results in a dramatic improvement in both GI and dermatologic symptoms; a prompt improvement following therapy can confirm the diagnosis. Blue rubber bleb nevus syndrome This is characterized by the combination of cutaneous vascular malformations and GI bleeding due

2014 eMedicine.com

20. Laser Treatment of Benign Pigmented Lesions (Treatment)

lesions. A typical treatment response includes purpura lasting 5-7 days, followed by subsequent sloughing of the treated lesion at 7-14 days. The underlying new skin is pink for 2-3 days but fades to normal skin color with rare textural changes or scarring. In another study, 25 patients with solar lentigines showed excellent laser-induced clearing after 1-2 treatments. Fourteen patients with café au lait macules showed complete clearing after 3-6 treatments. Two patients with nevus spilus and 2 (...) clearance, briefer pulse widths and treatment without cryogen cooling both, independently, decreased the fluence threshold. In 2001, Suh et al [ ] reported 71 Korean adult patients with superficial pigmented lesions (lentigines and solar lentigines) who demonstrated a very good response rate to multiple Q-switched Nd:YAG laser treatments. In 2003, Downs et al [ ] noted that the combination of the Q-switched Nd:YAG laser for café au lait spots, Becker nevi, speckled nevi, and congenital melanocytic nevi

2014 eMedicine.com

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