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Skin of Color

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102. Serum Vitamin D Depends Less on Latitude Than on Skin Color and Dietary Intake During Early Winter in Northern Europe. (PubMed)

Serum Vitamin D Depends Less on Latitude Than on Skin Color and Dietary Intake During Early Winter in Northern Europe. To evaluate if dietary vitamin D intake is adequate for sufficient vitamin D status during early winter in children living in Sweden, irrespective of latitude or skin color.As part of a prospective, comparative, 2-center intervention study in northern (63°N) and southern (55°N) Sweden, dietary intake, serum 25-hydroxyvitamin D (S-25(OH) D), associated laboratory variables (...) , and sociodemographic data were studied in 5 to 7-year-old children with fair and dark skin in November and December.Two hundred six children with fair/dark skin were included, 44/41 and 64/57 children in northern and southern Sweden, respectively. Dietary vitamin D intake was higher in northern than southern Sweden (P = 0.001), irrespective of skin color, partly due to higher consumption of fortified foods, but only met 50-70% of national recommendations (10 μg/day). S-25(OH) D was higher in northern than southern

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2015 Journal of Pediatric Gastroenterology and Nutrition

103. Race/skin color and obesity in adolescents: systematic review and meta-analysis

Race/skin color and obesity in adolescents: systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web address: Timing

2018 PROSPERO

104. Trihydroxybenzoic acid glucoside as a global skin color modulator and photo-protectant (PubMed)

Trihydroxybenzoic acid glucoside as a global skin color modulator and photo-protectant 3,4,5-Trihydroxybenzoic acid glucoside (THBG), a molecule produced by an original biocatalysis-based technology, was assessed in this study with respect to its skin photoprotective capacity and its skin color control property on Asian-type skin at a clinical level and on skin explant culture models.The double-blinded clinical study was done in comparison to a vehicle by the determination of objective color (...) parameters thanks to recognized quantitative and qualitative analysis tools, including Chroma-Meter, VISIA-CR™, and SIAscope™. Determination of L* (brightness), a* and b* (green-red and blue-yellow chromaticity coordinates), individual typology angle, and C* (chroma) and h* (hue angle) parameters using a Chroma-Meter demonstrated that THBG is able to modify skin color while quantification of ultraviolet (UV) spots by VISIA-CR™ confirmed its photoprotective effect. The mechanism of action of THBG molecule

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2015 Clinical, cosmetic and investigational dermatology

105. Microneedling in skin of color: A review of uses and efficacy. (PubMed)

Microneedling in skin of color: A review of uses and efficacy. In ethnic skin, traditional skin resurfacing procedures such as dermabrasion, chemical peels, and laser therapy can be effective but can also be associated with prolonged recovery and risk of complications. These complications can include a higher risk of dyspigmentation and scarring, and unsatisfactory clinical outcomes. Microneedling is an evolving treatment technique for an expanding number of dermatologic conditions (...) . Microneedling may offer a more advantageous safety profile, particularly in the skin-of-color population (Fitzpatrick skin types IV-VI), compared with more conventional resurfacing modalities. Thus far, it has been shown to be effective for a number of dermatologic conditions in this population, including scarring, melasma, melanosis, skin rejuvenation, acne vulgaris, and primary hyperhidrosis. This article aims to provide a comprehensive review of the literature regarding the efficacy and safety

2015 Journal of American Academy of Dermatology

106. Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up (PubMed)

Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up In the International Visible Trait Genetics (VisiGen) Consortium, we investigated the genetics of human skin color by combining a series of genome-wide association studies (GWAS) in a total of 17,262 Europeans with functional follow-up of discovered loci. Our GWAS provide the first genome-wide significant evidence for chromosome 20q11.22 harboring the ASIP gene being explicitly associated (...) with skin color in Europeans. In addition, genomic loci at 5p13.2 (SLC45A2), 6p25.3 (IRF4), 15q13.1 (HERC2/OCA2), and 16q24.3 (MC1R) were confirmed to be involved in skin coloration in Europeans. In follow-up gene expression and regulation studies of 22 genes in 20q11.22, we highlighted two novel genes EIF2S2 and GSS, serving as competing functional candidates in this region and providing future research lines. A genetically inferred skin color score obtained from the 9 top-associated SNPs from 9 genes

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2015 Human Genetics

107. Changes in Women’s Facial Skin Color over the Ovulatory Cycle are Not Detectable by the Human Visual System (PubMed)

Changes in Women’s Facial Skin Color over the Ovulatory Cycle are Not Detectable by the Human Visual System Human ovulation is not advertised, as it is in several primate species, by conspicuous sexual swellings. However, there is increasing evidence that the attractiveness of women's body odor, voice, and facial appearance peak during the fertile phase of their ovulatory cycle. Cycle effects on facial attractiveness may be underpinned by changes in facial skin color, but it is not clear (...) if skin color varies cyclically in humans or if any changes are detectable. To test these questions we photographed women daily for at least one cycle. Changes in facial skin redness and luminance were then quantified by mapping the digital images to human long, medium, and shortwave visual receptors. We find cyclic variation in skin redness, but not luminance. Redness decreases rapidly after menstrual onset, increases in the days before ovulation, and remains high through the luteal phase. However

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2015 PloS one

108. A Genome-Wide Association Study Identifies the Skin Color Genes IRF4, MC1R, ASIP, and BNC2 Influencing Facial Pigmented Spots. (PubMed)

A Genome-Wide Association Study Identifies the Skin Color Genes IRF4, MC1R, ASIP, and BNC2 Influencing Facial Pigmented Spots. Facial pigmented spots are a common skin aging feature, but genetic predisposition has yet to be thoroughly investigated. We conducted a genome-wide association study for pigmented spots in 2,844 Dutch Europeans from the Rotterdam Study (mean age: 66.9±8.0 years; 47% male). Using semi-automated image analysis of high-resolution digital facial photographs, facial (...) signals observed at all four loci were successfully replicated (P<0.05) in an independent Dutch cohort (Leiden Longevity Study n=599). Although the four genes have previously been associated with skin color variation and skin cancer risk, all association signals remained highly significant (P<2 × 10(-8)) when conditioning the association analyses on skin color. We conclude that genetic variations in IRF4, MC1R, RALY/ASIP, and BNC2 contribute to the acquired amount of facial pigmented spots during

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2015 Journal of Investigative Dermatology

109. Black Patients' Lived Experiences and Perceptions of Skin of Color Clinics

Black Patients' Lived Experiences and Perceptions of Skin of Color Clinics Black Patients' Lived Experiences and Perceptions of Skin of Color Clinics - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Black (...) Patients' Lived Experiences and Perceptions of Skin of Color Clinics The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02375659 Recruitment Status : Completed First Posted : March 2, 2015 Last Update Posted : October 26, 2017 Sponsor: Northwestern University Collaborator: University of Wisconsin, Stout

2015 Clinical Trials

110. Hair loss in patients with skin of color. (PubMed)

Hair loss in patients with skin of color. Hair loss in skin of color patients can vary from the very simplest of diagnoses to a unique diagnostic challenge requiring extensive knowledge of historical symptoms, haircare practices, and previous treatments. There are several disorders in the literature that are noted to be more common in patients of African descent as compared to Caucasian populations. These disorders include central centrifugal cicatricial alopecia, dissecting cellulitis, discoid (...) lesions of lupus erythematosus, traction alopecia, seborrheic dermatitis, and hair breakage. While there is no definitive prevalence data for the various forms of hair loss in the skin of color population, it is clear that these disorders are a concern for many patients in this population along with common hair loss concerns, such as telogen effluvium and pattern hair loss. A careful detailed clinical examination, history, and potential histopathology will guide the clinician to appropriate management

2015 Seminars in Cutaneous Medicine and Surgery

111. Changing Skin Color (PubMed)

Changing Skin Color 26157305 2015 07 09 2018 11 13 0974-2077 8 2 2015 Apr-Jun Journal of cutaneous and aesthetic surgery J Cutan Aesthet Surg Changing Skin Color. 77-8 10.4103/0974-2077.158435 Khunger Niti N Department of Dermatology and Sexually Transmitted Diseases, Vardhman Mahavir Medical College and Safdarjang Hospital, New Delhi, India. eng Journal Article India J Cutan Aesthet Surg 101525405 0974-2077 2015 7 10 6 0 2015 7 15 6 0 2015 7 15 6 1 ppublish 26157305 10.4103/0974-2077.158435

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2015 Journal of cutaneous and aesthetic surgery

112. AIUM Practice Parameter for the Performance of Peripheral Arterial Ultrasound Examinations Using Color and Spectral Doppler Imaging

AIUM Practice Parameter for the Performance of Peripheral Arterial Ultrasound Examinations Using Color and Spectral Doppler Imaging AIUM Practice Parameter for the Performance of Peripheral Arterial Ultrasound Examinations Using Color and Spectral Doppler Imaging © 2014 by the American Institute of Ultrasound in Medicine Parameter developed in collaboration with the American College of Radiology (ACR) and the Society of Radiologists in Ultrasound (SRU). peripheralArterial.qxp_1115 12/1/15 3:26 (...) of Peripheral Arterial Ultrasound Examinations Using Color and Spectral Doppler Imaging. The AIUM represents the entire range of clinical and basic science interests in medical diagnostic ultrasound, and, with hundreds of vol- unteers, this multidisciplinary organization has promoted the safe and effective use of ultrasound in clinical medicine for more than 50 years. This document and others like it will continue to advance this mission. Practice parameters of the AIUM are intended to provide the medical

2014 American Institute of Ultrasound in Medicine

113. Phloxine O, a Cosmetic Colorant, Suppresses the Expression of Thymic Stromal Lymphopoietin and Acute Dermatitis Symptoms in Mice (PubMed)

Phloxine O, a Cosmetic Colorant, Suppresses the Expression of Thymic Stromal Lymphopoietin and Acute Dermatitis Symptoms in Mice Cosmetics are primarily applied to the skin; therefore, the association of cosmetic dyes with skin diseases or inflammation is a topic of great interest. Thymic stromal lymphopoietin (TSLP) is an interleukin 7-like cytokine that activates dendritic cells to promote Th2 inflammatory immune responses. TSLP is highly expressed in keratinocytes under inflammatory (...) conditions, which suggests that it may play a critical role in the development of skin diseases, such as atopic dermatitis. Therefore, we investigated whether cosmetic dyes influenced the production of TSLP by keratinocytes. Phloxine O, also known as D&C Red No.27, is one of the most common red synthetic pigments and is widely used in colored cosmetics. Our results showed that Phloxine O downregulated phorbol 12-myristate 13-acetate-induced production of TSLP in a murine keratinocyte cell line (PAM212

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2018 Biomolecules & therapeutics

114. Molecular-channel driven actuator with considerations for multiple configurations and color switching (PubMed)

Molecular-channel driven actuator with considerations for multiple configurations and color switching The ability to achieve simultaneous intrinsic deformation with fast response in commercially available materials that can safely contact skin continues to be an unresolved challenge for artificial actuating materials. Rather than using a microporous structure, here we show an ambient-driven actuator that takes advantage of inherent nanoscale molecular channels within a commercial

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2018 Nature communications

115. The pattern of color change in small mammal museum specimens: is it independent of storage histories given museum-specific conditions? (PubMed)

that there is a relationship between specimen storage antiquity and pelage color and it seems that it is general for at least a number of small mammals and this could indicate a universal phenomenon across several mammal species and across several storage conditions. Our results, as others, emphasize the importance of considering storage time, among other circumstances, in research studies using mammal skins and where color is of importance. (...) The pattern of color change in small mammal museum specimens: is it independent of storage histories given museum-specific conditions? Determination of color and evaluating its variation form the basis for a broad range of research questions. For studies on taxonomy, systematics, etc., resorting to mammal specimens in museum collections has a number of advantages over using field specimens. However, if museum specimens are to be for studying color, they should accurately represent the color

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2018 BMC research notes

116. New Insights into the Melanophilin (MLPH) Gene Affecting Coat Color Dilution in Rabbits (PubMed)

>A variant that is located in an acceptor splice site or the c.585delG variant, a frameshift mutation. On the transcript level, the skipping of two exons has been reported as the molecular mechanism responsible for the coat color dilution. To clarify, which of the two variants represents the causal variant, (i) we analyzed their allelic segregation by genotyping Castor and Chinchilla populations, and (ii) we evaluated their functional effects on the stability of MLPH transcripts in skin samples (...) New Insights into the Melanophilin (MLPH) Gene Affecting Coat Color Dilution in Rabbits Coat color dilution corresponds to a specific pigmentation phenotype that leads to a dilution of wild type pigments. It affects both eumelanin and pheomelanin containing melanosomes. The mode of inheritance of the dilution phenotype is autosomal recessive. Candidate gene approaches focused on the melanophilin (MLPH) gene highlighted two variants associated with the dilution phenotype in rabbits: The c.111-5C

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2018 Genes

117. Comparative genomics and transcriptomics of Chrysolophus provide insights into the evolution of complex plumage coloration (PubMed)

Comparative genomics and transcriptomics of Chrysolophus provide insights into the evolution of complex plumage coloration As one of the most recognizable characteristics in birds, plumage color has a high impact on understanding the evolution and mechanisms of coloration. Feather and skin are ideal tissues to explore the genomics and complexity of color patterns in vertebrates. Two species of the genus Chrysolophus, golden pheasant (Chrysolophus pictus) and Lady Amherst's pheasant (...) (Chrysolophus amherstiae), exhibit brilliant colors in their plumage, but with extreme phenotypic differences, making these two species great models to investigate plumage coloration mechanisms in birds.We sequenced and assembled a genome of golden pheasant with high coverage and annotated 15,552 protein-coding genes. The genome of Lady Amherst's pheasant is sequenced with low coverage. Based on the feather pigment identification, a series of genomic and transcriptomic comparisons were conducted

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2018 GigaScience

118. MKSAP: 25-year-old man with dark-colored urine

MKSAP: 25-year-old man with dark-colored urine Poststreptococcal glomerulonephritis is characterized these preceding symptoms MKSAP: 25-year-old man with dark-colored urine | | August 25, 2018 1 Shares Test your medicine knowledge with the , in partnership with the . A 25-year-old man is evaluated for dark-colored urine for 2 days, swelling of the face and hands for 1 day, and severe headaches this morning. He reports having an upper respiratory tract infection 1 week ago with fever, sore (...) throat, and swollen glands, but had otherwise felt well. Medical history is otherwise unremarkable, and he takes no medications. On physical examination, temperature is 37.2 °C (99.0 °F), blood pressure is 180/90 mm Hg, pulse rate is 88/min, and respiration rate is 14/min. Cardiopulmonary and abdominal examinations are normal. No skin rash or arthritis is present. There is bilateral lower extremity edema to the mid shins. Laboratory studies: Albumin 3.3 g/dL (33 g/L) C3 Low C4 Normal Creatinine 1.4

2018 KevinMD blog

119. Skin cancer and photoprotection in people of color: A review and recommendations for physicians and the public. (PubMed)

Skin cancer and photoprotection in people of color: A review and recommendations for physicians and the public. Skin cancer is less prevalent in people of color than in the white population. However, when skin cancer occurs in non-whites, it often presents at a more advanced stage, and thus the prognosis is worse compared with white patients. The increased morbidity and mortality associated with skin cancer in patients of color compared with white patients may be because of the lack (...) of awareness, diagnoses at a more advanced stage, and socioeconomic factors such as access to care barriers. Physician promotion of skin cancer prevention strategies for all patients, regardless of ethnic background and socioeconomic status, can lead to timely diagnosis and treatment. Public education campaigns should be expanded to target communities of color to promote self-skin examination and stress importance of photoprotection, avoidance of tanning bed use, and early skin cancer detection

2014 Journal of American Academy of Dermatology

120. Choloperitoneum causes extensive coloring of the abdominal wall skin. (PubMed)

Choloperitoneum causes extensive coloring of the abdominal wall skin. Laparoscopic cholecystectomy, because it is the less invasive surgical procedure, has been established as the procedure of choice for the treatment of patients with symptomatic gallbladder stones. However, bile leakage after laparoscopic cholecystectomy should not be overlooked. It is generally due to a minor biliary complication, although it can sometimes herald a major duct injury. Bile leakage rates of 1.2% to 4.0

2014 American Journal of Emergency Medicine

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