How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

6,101 results for

Skin of Color

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

81. Comparative Transcriptome Analysis Identifies Candidate Genes Related to Skin Color Differentiation in Red Tilapia Full Text available with Trip Pro

Comparative Transcriptome Analysis Identifies Candidate Genes Related to Skin Color Differentiation in Red Tilapia Red tilapia is becoming more popular for aquaculture production in China in recent years. However, the pigmentation differentiation in genetic breeding is the main problem limiting its development of commercial red tilapia culture and the genetic basis of skin color variation is still unknown. In this study, we conducted Illumina sequencing of transcriptome on three color variety (...) and the results revealed that there were 148 common significantly differentially expressed unigenes and several key genes related to pigment synthesis, i.e. tyr, tyrp1, silv, sox10, slc24a5, cbs and slc7a11, were included. The results will facilitate understanding the molecular mechanisms of skin pigmentation differentiation in red tilapia and accelerate the molecular selection of the specific strain with consistent skin colors.

2016 Scientific reports

82. Dermoscopy-guided reflectance confocal microscopy of skin using high-NA objective lens with integrated wide-field color camera Full Text available with Trip Pro

Dermoscopy-guided reflectance confocal microscopy of skin using high-NA objective lens with integrated wide-field color camera Reflectance Confocal Microscopy, or RCM, is being increasingly used to guide diagnosis of skin lesions. The combination of widefield dermoscopy (WFD) with RCM is highly sensitive (~90%) and specific (~ 90%) for noninvasively detecting melanocytic and non-melanocytic skin lesions. The combined WFD and RCM approach is being implemented on patients to triage lesions (...) , providing simultaneous wide-field color images of the skin surface and RCM images of the subsurface cellular structure. The objective lens (0.9 NA) includes a hyperhemisphere lens and an ultra-miniature CMOS color camera, commanding a 4 mm wide dermoscopy view of the skin surface. The camera obscures the central portion of the aperture of the objective lens, but the resulting annular aperture provides excellent RCM optical sectioning and resolution. Preliminary testing on healthy volunteers showed

2016 Proceedings of SPIE--the International Society for Optical Engineering

83. Skin Cancer Concerns in People of Color: Risk Factors and Prevention Full Text available with Trip Pro

Skin Cancer Concerns in People of Color: Risk Factors and Prevention Background: Though people of color (POC) are less likely to become afflicted with skin cancer, they are much more likely to die from it due to delay in detection or presentation. Very often, skin cancer is diagnosed at a more advanced stage in POC, making treatment difficult.The purpose of this research was to improve awareness regarding skin cancers in people of color by providing recommendations to clinicians and the general (...) public for early detection and photo protection preventive measures. Methods: Data on different types of skin cancers were presented to POC. Due to limited research, there are few resources providing insights for evaluating darkly pigmented lesions in POC. Diagnostic features for different types of skin cancers were recorded and various possible risk factors were considered. Results: This study provided directions for the prevention and early detection of skin cancer in POC based on a comprehensive

2016 Asian Pacific journal of cancer prevention : APJCP

84. Expression and Distribution of the Guanine Nucleotide-binding Protein Subunit Alpha-s in Mice Skin Tissues and Its Association with White and Black Coat Colors Full Text available with Trip Pro

Expression and Distribution of the Guanine Nucleotide-binding Protein Subunit Alpha-s in Mice Skin Tissues and Its Association with White and Black Coat Colors Guanine nucleotide-binding protein subunit alpha-s (Gnαs) is a small subunit of the G protein-couple signaling pathway, which is involved in the formation of coat color. The expression level and distribution of Gnαs were detected by quantitative real-time-polymerase chain reaction (qPCR), western blot, and immunohistochemistry (...) to investigate the underlying mechanisms of coat color in white and black skin tissues of mice. qPCR and western blot results suggested that Gnαs was expressed at significantly higher levels in black mice compared with that of white mice, and transcripts and protein possessed the same expression in both colors. Immunohistochemistry demonstrated Gnαs staining in the root sheath and dermal papilla in hair follicle of mice skins. The results indicated that the Gnαs gene was expressed in both white and black

2016 Asian-Australasian journal of animal sciences

85. Pharmacokinetics of MB-102 and Use of the Non-invasive Optical Renal Function Monitor (ORFM) Device in Subjects With Normal and Impaired Renal Function and a Range of Skin Color Types

Pharmacokinetics of MB-102 and Use of the Non-invasive Optical Renal Function Monitor (ORFM) Device in Subjects With Normal and Impaired Renal Function and a Range of Skin Color Types Pharmacokinetics of MB-102 and Use of the Non-invasive Optical Renal Function Monitor (ORFM) Device in Subjects With Normal and Impaired Renal Function and a Range of Skin Color Types - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration (...) or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Pharmacokinetics of MB-102 and Use of the Non-invasive Optical Renal Function Monitor (ORFM) Device in Subjects With Normal and Impaired Renal Function and a Range of Skin Color Types The safety and scientific validity of this study is the responsibility of the study sponsor

2016 Clinical Trials

86. Facial Hyperpigmentation in Skin of Color: Special Considerations and Treatment. (Abstract)

Facial Hyperpigmentation in Skin of Color: Special Considerations and Treatment. Differences in cutaneous diseases in people of color call for nuanced evaluation and management. One of the most common dermatological complaints from patients with skin of color is dyspigmentation, particularly hyperpigmentation. The challenge for clinicians is to establish correct diagnoses along with consistently successful treatments to meet the needs of the increasingly diverse population served. This review (...) focuses on facial hyperpigmentation and outlines the most common skin disorders and treatment options.

2016 American journal of clinical dermatology

87. What Is the Utility of Ultrasonography for the Identification of Skin and Soft Tissue Infections in the Emergency Department? Full Text available with Trip Pro

What Is the Utility of Ultrasonography for the Identification of Skin and Soft Tissue Infections in the Emergency Department? What Is the Utility of Ultrasonography for the Identification of Skin and Soft Tissue Infections in the Emergency Department? - Annals of Emergency Medicine Email/Username: Password: Remember me Search Terms Search within Search Share this page Access provided by Volume 70, Issue 4, Pages 580–582 What Is the Utility of Ultrasonography for the Identification of Skin (...) and Soft Tissue Infections in the Emergency Department? x Michael Gottlieb , MD, RDMS (EBEM Commentator) , x Ananda Vishnu Pandurangadu , MD (EBEM Commentator) Department of Emergency Medicine, Rush University Medical Center, Chicago, IL DOI: | Publication History Published online: March 15, 2017 Expand all Collapse all Article Outline Take-Home Message Point-of-care ultrasonographic examination of skin and soft tissue infections enhances the ability to differentiate abscesses from cellulitis. Methods

2017 Annals of Emergency Medicine Systematic Review Snapshots

88. What Is the Utility of Ultrasonography for the Identification of Skin and Soft Tissue Infections in the Emergency Department?

What Is the Utility of Ultrasonography for the Identification of Skin and Soft Tissue Infections in the Emergency Department? TAKE-HOME MESSAGE Point-of-care ultrasonographic examination of skin and soft tissue infections enhances the ability to differentiate abscesses from cellulitis. What Is the Utility of Ultrasonography for the Identi?cationofSkinandSoftTissueInfectionsinthe Emergency Department? EBEM Commentators Michael Gottlieb, MD, RDMS Ananda Vishnu Pandurangadu, MD Department (...) of ultrasonography ranged from 90% to 98% and the speci?city ranged from 67% to 88% in the 6 initially included trials. The sensi- tivity of clinical examination ranged from 75% to 95% and the speci?city ranged from 60% to 84%. After removal of the study by Marin et al, 1 the pooled sensitivity andspeci?cityforultrasonography in the remaining trials were 97% and 83%, respectively (see Table). Operating characteristics of ultrasonography for the evaluation of skin and soft tissue infections. Operating

2017 Annals of Emergency Medicine Systematic Review Snapshots

89. Skin Cancer Prevention: Behavioral Counseling

years with fair skin type Skin self-examination in adults Recommendation Counsel about minimizing exposure to UV radiation. Grade: B Selectively offer counseling about minimizing exposure to UV radiation. Grade: C No recommendation. Grade: I (insufficient evidence) Risk Assessment Ultraviolet radiation exposure during childhood and adolescence increases risk of skin cancer later in life, especially when more severe damage occurs. Persons with fair skin type (light hair and eye color, freckles, those (...) . Recognition of Risk Status Exposure to UV radiation during childhood and adolescence increases the risk of skin cancer later in life, especially when more severe damage occurs, such as with severe sunburns. Persons with fair skin types (ivory or pale skin, light hair and eye color, freckles, or those who sunburn easily) are at increased risk of skin cancer. Persons who use tanning beds and those with a history of sunburns or previous skin cancer are also at substantially increased risk of skin cancer

2018 U.S. Preventive Services Task Force

90. Contact sensitization to hair colors in acquired dermal macular hyperpigmentation: Results from a patch and photo patch-test study of 108 patients. (Abstract)

Contact sensitization to hair colors in acquired dermal macular hyperpigmentation: Results from a patch and photo patch-test study of 108 patients. Acquired dermal macular hyperpigmentation (ADMH) is an umbrella term including lichen planus pigmentosus, erythema dyschromicum perstans and pigmented contact/cosmetic dermatitis.To establish contact sensitization to hair colours as an aetiological factor for ADMH.Detailed clinical examination, skin biopsies, and patch and photo-patch testing

2019 Journal of the European Academy of Dermatology and Venereology

91. Microneedling in skin of color: A review of uses and efficacy. (Abstract)

Microneedling in skin of color: A review of uses and efficacy. In ethnic skin, traditional skin resurfacing procedures such as dermabrasion, chemical peels, and laser therapy can be effective but can also be associated with prolonged recovery and risk of complications. These complications can include a higher risk of dyspigmentation and scarring, and unsatisfactory clinical outcomes. Microneedling is an evolving treatment technique for an expanding number of dermatologic conditions (...) . Microneedling may offer a more advantageous safety profile, particularly in the skin-of-color population (Fitzpatrick skin types IV-VI), compared with more conventional resurfacing modalities. Thus far, it has been shown to be effective for a number of dermatologic conditions in this population, including scarring, melasma, melanosis, skin rejuvenation, acne vulgaris, and primary hyperhidrosis. This article aims to provide a comprehensive review of the literature regarding the efficacy and safety

2015 Journal of American Academy of Dermatology

92. Serum Vitamin D Depends Less on Latitude Than on Skin Color and Dietary Intake During Early Winter in Northern Europe. (Abstract)

Serum Vitamin D Depends Less on Latitude Than on Skin Color and Dietary Intake During Early Winter in Northern Europe. To evaluate if dietary vitamin D intake is adequate for sufficient vitamin D status during early winter in children living in Sweden, irrespective of latitude or skin color.As part of a prospective, comparative, 2-center intervention study in northern (63°N) and southern (55°N) Sweden, dietary intake, serum 25-hydroxyvitamin D (S-25(OH) D), associated laboratory variables (...) , and sociodemographic data were studied in 5 to 7-year-old children with fair and dark skin in November and December.Two hundred six children with fair/dark skin were included, 44/41 and 64/57 children in northern and southern Sweden, respectively. Dietary vitamin D intake was higher in northern than southern Sweden (P = 0.001), irrespective of skin color, partly due to higher consumption of fortified foods, but only met 50-70% of national recommendations (10 μg/day). S-25(OH) D was higher in northern than southern

2015 Journal of Pediatric Gastroenterology and Nutrition

93. Trihydroxybenzoic acid glucoside as a global skin color modulator and photo-protectant Full Text available with Trip Pro

Trihydroxybenzoic acid glucoside as a global skin color modulator and photo-protectant 3,4,5-Trihydroxybenzoic acid glucoside (THBG), a molecule produced by an original biocatalysis-based technology, was assessed in this study with respect to its skin photoprotective capacity and its skin color control property on Asian-type skin at a clinical level and on skin explant culture models.The double-blinded clinical study was done in comparison to a vehicle by the determination of objective color (...) parameters thanks to recognized quantitative and qualitative analysis tools, including Chroma-Meter, VISIA-CR™, and SIAscope™. Determination of L* (brightness), a* and b* (green-red and blue-yellow chromaticity coordinates), individual typology angle, and C* (chroma) and h* (hue angle) parameters using a Chroma-Meter demonstrated that THBG is able to modify skin color while quantification of ultraviolet (UV) spots by VISIA-CR™ confirmed its photoprotective effect. The mechanism of action of THBG molecule

2015 Clinical, cosmetic and investigational dermatology

95. Black Patients' Lived Experiences and Perceptions of Skin of Color Clinics

Black Patients' Lived Experiences and Perceptions of Skin of Color Clinics Black Patients' Lived Experiences and Perceptions of Skin of Color Clinics - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Black (...) Patients' Lived Experiences and Perceptions of Skin of Color Clinics The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02375659 Recruitment Status : Completed First Posted : March 2, 2015 Last Update Posted : October 26, 2017 Sponsor: Northwestern University Collaborator: University of Wisconsin, Stout

2015 Clinical Trials

96. Daily Consumption of a Fruit and Vegetable Smoothie Alters Facial Skin Color. Full Text available with Trip Pro

Daily Consumption of a Fruit and Vegetable Smoothie Alters Facial Skin Color. Consumption of dietary carotenoids or carotenoid supplements can alter the color (yellowness) of human skin through increased carotenoid deposition in the skin. As fruit and vegetables are the main dietary sources of carotenoids, skin yellowness may be a function of regular fruit and vegetable consumption. However, most previous studies have used tablets or capsules to supplement carotenoid intake, and less is known (...) of the impact of increased fruit and vegetable consumption on skin color. Here, we examined skin color changes in an Asian population (Malaysian Chinese ethnicity) over a six week dietary intervention with a carotenoid-rich fruit smoothie. Eighty one university students (34 males, 47 females; mean age 20.48) were assigned randomly to consuming either a fruit smoothie (intervention group) or mineral water (control group) daily for six weeks. Participants' skin yellowness (CIELab b*), redness

2015 PloS one Controlled trial quality: uncertain

97. The treatment of keloids and hypertrophic scars with intralesional bleomycin in skin of color. (Abstract)

The treatment of keloids and hypertrophic scars with intralesional bleomycin in skin of color. Intralesional injection with corticosteroid remains the mainstay of therapy for hypertrophic scars and keloids, however some lesions are unresponsive or may result in skin atrophy. Intralesional bleomycin injection is an alternative therapy that has been widely reported. In order to compare the effectiveness and safety of bleomycin for the treatment of keloids and hypertrophic scars in skin of color (...) population, Fitzpatrick skin type III to V patients with keloids or hypertrophic scars were randomized into two groups. Group A was treated monthly with intralesional triamcinolone acetonide (10 mg/mL), while group B with intralesional bleomycin (1 mg/mL) for three consecutive months. Evaluation of the treatment was performed using "Patient and Observer Scar Assessment Scale" (POSAS), self-rated patient satisfaction score, photography, and ultrasonography. Two patients had their bleomycin blood levels

2015 Journal of cosmetic dermatology Controlled trial quality: uncertain

98. A Genome-Wide Association Study Identifies the Skin Color Genes IRF4, MC1R, ASIP, and BNC2 Influencing Facial Pigmented Spots. Full Text available with Trip Pro

A Genome-Wide Association Study Identifies the Skin Color Genes IRF4, MC1R, ASIP, and BNC2 Influencing Facial Pigmented Spots. Facial pigmented spots are a common skin aging feature, but genetic predisposition has yet to be thoroughly investigated. We conducted a genome-wide association study for pigmented spots in 2,844 Dutch Europeans from the Rotterdam Study (mean age: 66.9±8.0 years; 47% male). Using semi-automated image analysis of high-resolution digital facial photographs, facial (...) signals observed at all four loci were successfully replicated (P<0.05) in an independent Dutch cohort (Leiden Longevity Study n=599). Although the four genes have previously been associated with skin color variation and skin cancer risk, all association signals remained highly significant (P<2 × 10(-8)) when conditioning the association analyses on skin color. We conclude that genetic variations in IRF4, MC1R, RALY/ASIP, and BNC2 contribute to the acquired amount of facial pigmented spots during

2015 Journal of Investigative Dermatology

99. Changes in Women’s Facial Skin Color over the Ovulatory Cycle are Not Detectable by the Human Visual System Full Text available with Trip Pro

Changes in Women’s Facial Skin Color over the Ovulatory Cycle are Not Detectable by the Human Visual System Human ovulation is not advertised, as it is in several primate species, by conspicuous sexual swellings. However, there is increasing evidence that the attractiveness of women's body odor, voice, and facial appearance peak during the fertile phase of their ovulatory cycle. Cycle effects on facial attractiveness may be underpinned by changes in facial skin color, but it is not clear (...) if skin color varies cyclically in humans or if any changes are detectable. To test these questions we photographed women daily for at least one cycle. Changes in facial skin redness and luminance were then quantified by mapping the digital images to human long, medium, and shortwave visual receptors. We find cyclic variation in skin redness, but not luminance. Redness decreases rapidly after menstrual onset, increases in the days before ovulation, and remains high through the luteal phase. However

2015 PloS one

100. Hair loss in patients with skin of color. (Abstract)

Hair loss in patients with skin of color. Hair loss in skin of color patients can vary from the very simplest of diagnoses to a unique diagnostic challenge requiring extensive knowledge of historical symptoms, haircare practices, and previous treatments. There are several disorders in the literature that are noted to be more common in patients of African descent as compared to Caucasian populations. These disorders include central centrifugal cicatricial alopecia, dissecting cellulitis, discoid (...) lesions of lupus erythematosus, traction alopecia, seborrheic dermatitis, and hair breakage. While there is no definitive prevalence data for the various forms of hair loss in the skin of color population, it is clear that these disorders are a concern for many patients in this population along with common hair loss concerns, such as telogen effluvium and pattern hair loss. A careful detailed clinical examination, history, and potential histopathology will guide the clinician to appropriate management

2015 Seminars in Cutaneous Medicine and Surgery

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>