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Skin of Color

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21. Comparative microRNA-seq Analysis Depicts Candidate miRNAs Involved in Skin Color Differentiation in Red Tilapia (PubMed)

Comparative microRNA-seq Analysis Depicts Candidate miRNAs Involved in Skin Color Differentiation in Red Tilapia Differentiation and variation in body color has been a growing limitation to the commercial value of red tilapia. Limited microRNA (miRNA) information is available on skin color differentiation and variation in fish so far. In this study, a high-throughput Illumina sequencing of sRNAs was conducted on three color varieties of red tilapia and 81,394,491 raw reads were generated (...) . A total of 158 differentially expressed miRNAs (|log₂(fold change)| ≥ 1 and q-value ≤ 0.001) were identified. Target prediction and functional analysis of color-related miRNAs showed that a variety of putative target genes—including slc7a11, mc1r and asip—played potential roles in pigmentation. Moreover; the miRNA-mRNA regulatory network was illustrated to elucidate the pigmentation differentiation, in which miR-138-5p and miR-722 were predicted to play important roles in regulating

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2018 International journal of molecular sciences

22. TRP-2 mediates coat color pigmentation in sheep skin (PubMed)

TRP-2 mediates coat color pigmentation in sheep skin Tyrosinase‑related protein 2 (TRP‑2) is one of the most important members of the tyrosinase family, and is a key enzyme involved in melanin biosynthesis. In the present study, a skin transcriptome profile, immunohistochemistry, western blotting and reverse transcription‑quantitative polymerase chain reaction were used to investigate TRP‑2 expression in sheep with different coat colors, namely, black, white and black‑white. TRP‑2 (...) . Therefore, TRP‑2 may affect melanin production in sheep, and different expression levels determine coat color. The results may provide novel approaches for developing therapeutic strategies for skin diseases associated with pigmentation disorders.

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2018 Molecular medicine reports

23. Enstilar® Foam in the Treatment of Chronic Plaque Psoriasis in Patients With Skin of Color

Enstilar® Foam in the Treatment of Chronic Plaque Psoriasis in Patients With Skin of Color Enstilar® Foam in the Treatment of Chronic Plaque Psoriasis in Patients With Skin of Color - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) studies before adding more. Enstilar® Foam in the Treatment of Chronic Plaque Psoriasis in Patients With Skin of Color The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03506477 Recruitment Status : Recruiting First Posted

2018 Clinical Trials

24. The Use of Onexton in Moderate Acne Vulgaris for Patients With Skin of Color

The Use of Onexton in Moderate Acne Vulgaris for Patients With Skin of Color The Use of Onexton in Moderate Acne Vulgaris for Patients With Skin of Color - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . The Use of Onexton in Moderate Acne Vulgaris for Patients With Skin of Color The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03402893 Recruitment Status : Completed First Posted : January 18, 2018 Results First Posted : February 19, 2019 Last Update Posted : March 19, 2019 Sponsor: Derm Research, PLLC

2018 Clinical Trials

25. Acne Scarring in Skin of Color: Laser vs Microneedling

Acne Scarring in Skin of Color: Laser vs Microneedling Acne Scarring in Skin of Color: Laser vs Microneedling - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Acne Scarring in Skin of Color: Laser vs (...) lasers, subcision, and peels, none is without risk of adverse effects of pain, post-procedure redness or pigmentary changes. There have been no randomized studies directly comparing the effectiveness and safety profiles of microneedling (Dermapen) to 1,540nm nonablative fractional lasers (Palomar StarLux) in the treatment of atrophic acne scarring in skin of color. This clinical trial aims to determine which treatment modality -- microneedling or nonablative fractional laser -- is safer and more

2018 Clinical Trials

26. Aczone Gel 7.5% in the Treatment of Acne Vulgaris in Patients With Skin of Color

Aczone Gel 7.5% in the Treatment of Acne Vulgaris in Patients With Skin of Color Aczone Gel 7.5% in the Treatment of Acne Vulgaris in Patients With Skin of Color - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding (...) more. Aczone Gel 7.5% in the Treatment of Acne Vulgaris in Patients With Skin of Color The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03681470 Recruitment Status : Not yet recruiting First Posted : September 24, 2018

2018 Clinical Trials

27. Identification and characterization of skin color microRNAs in Koi carp (Cyprinus carpio L.) by Illumina sequencing (PubMed)

Identification and characterization of skin color microRNAs in Koi carp (Cyprinus carpio L.) by Illumina sequencing MicroRNAs (miRNAs) are endogenous, small (21-25 nucleotide), non-coding RNAs that play important roles in numerous biological processes. Koi carp exhibit diverse color patterns, making it an ideal subject for studying the genetics of pigmentation. However, the influence of miRNAs on skin color regulation and variation in Koi carp is poorly understood.Herein, we performed small RNA (...) (sRNA) analysis of the three main skin colors in Koi carp by Illumina sequencing. The results revealed 330, 397, and 335 conserved miRNAs (belonging to 81 families) and 340, 353, and 351 candidate miRNAs in black, red, and white libraries, respectively. A total of 164 differentially expressed miRNAs (DEMs) and 14 overlapping DEMs were identified, including miR-196a, miR-125b, miR-202, miR-205-5p, miR-200b, and etc. Target prediction and functional analysis of color-related miRNAs such as miR-200b

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2018 BMC genomics

28. Skin Disease Recognition Method Based on Image Color and Texture Features (PubMed)

Skin Disease Recognition Method Based on Image Color and Texture Features Skin diseases have a serious impact on people's life and health. Current research proposes an efficient approach to identify singular type of skin diseases. It is necessary to develop automatic methods in order to increase the accuracy of diagnosis for multitype skin diseases. In this paper, three type skin diseases such as herpes, dermatitis, and psoriasis skin disease could be identified by a new recognition method (...) . Initially, skin images were preprocessed to remove noise and irrelevant background by filtering and transformation. Then the method of grey-level co-occurrence matrix (GLCM) was introduced to segment images of skin disease. The texture and color features of different skin disease images could be obtained accurately. Finally, by using the support vector machine (SVM) classification method, three types of skin diseases were identified. The experimental results demonstrate the effectiveness and feasibility

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2018 Computational and mathematical methods in medicine

29. Comparison of radiation dermatitis between hypofractionated and conventionally fractionated postoperative radiotherapy: objective, longitudinal assessment of skin color (PubMed)

Comparison of radiation dermatitis between hypofractionated and conventionally fractionated postoperative radiotherapy: objective, longitudinal assessment of skin color This study aimed to quantitatively compare radiation dermatitis due to hypofractionated (Hypo) and conventionally fractionated (Conv) external-beam radiotherapy in patients who underwent postoperative radiotherapy after breast-conserving surgery. Skin color changes, in terms of L* (brightness, white-black), a* (red-green), and b (...) * (yellow-blue) values, due to external-beam radiotherapy were examined at alternate fractions using an objective method. Twenty-six patients were included in the Hypo group (42.56 Gy/16 fractions) and 46 in the Conv group (50 Gy/25 fractions). Radiotherapy decreased the L* value (darker) and increased the a* value (redder) gradually. These color alterations progressed linearly according to elapsed fractions and were similar between Hypo and Conv per fraction. The Hypo group showed significantly milder

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2018 Scientific reports

30. Actinic comedonal plaque in skin of color: A case report (PubMed)

Actinic comedonal plaque in skin of color: A case report Actinic comedonal plaque is a variant of Favre-Racouchot syndrome which is a complication of solar degeneration of the skin. It is common in skin types 1-4 and unknown to rare in skin of color. This case report should create an awareness of this disease so not to be missed.

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2018 Clinical Case Reports

31. Skin color-specific and spectrally-selective naked-eye dosimetry of UVA, B and C radiations (PubMed)

Skin color-specific and spectrally-selective naked-eye dosimetry of UVA, B and C radiations Spectrally-selective monitoring of ultraviolet radiations (UVR) is of paramount importance across diverse fields, including effective monitoring of excessive solar exposure. Current UV sensors cannot differentiate between UVA, B, and C, each of which has a remarkably different impact on human health. Here we show spectrally selective colorimetric monitoring of UVR by developing a photoelectrochromic ink (...) that consists of a multi-redox polyoxometalate and an e- donor. We combine this ink with simple components such as filter paper and transparency sheets to fabricate low-cost sensors that provide naked-eye monitoring of UVR, even at low doses typically encountered during solar exposure. Importantly, the diverse UV tolerance of different skin colors demands personalized sensors. In this spirit, we demonstrate the customized design of robust real-time solar UV dosimeters to meet the specific need of different

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2018 Nature communications

32. Reversible reddish skin color change in a patient with compressive radial neuropathy. (PubMed)

Reversible reddish skin color change in a patient with compressive radial neuropathy. The motor and sensory symptoms caused by compressive radial neuropathy are well-known, but the involvement of the autonomic nervous system or the dermatologic symptoms are less well known. We report an unusual case of compressive radial neuropathy with reversible reddish skin color change.A 42-year-old man was referred for left wrist drop, finger drop and a tingling sensation over the lateral dorsum (...) of the left hand. Based on clinical information, neurologic examinations and electrophysiologic studies, he was diagnosed with compressive radial neuropathy. In addition, a reddish skin color change was observed at the area of radial sensory distribution. After two weeks of observation without specific treatment, the skin color had recovered along with a marked improvement in weakness and aberrant sensation.Compressive radial neuropathy with a reversible reddish skin color change is unusual

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2018 BMC Neurology

33. Aesthetic considerations in female skin of color: what you need to know. (PubMed)

Aesthetic considerations in female skin of color: what you need to know. The world is flat when it comes to aesthetic treatments, meaning women and men from all walks of life, regardless of culture and ethnicity or even socioeconomic status, are seeking ways to improve their appearance, prevent aging, and rejuvenate their skin. Year after year, statistics show a steady increase in people of color undergoing aesthetic treatments, with neurotoxins, fillers, laser resurfacing, and body contouring

2018 Seminars in Cutaneous Medicine and Surgery

34. Association between race/skin color and premature birth: a systematic review with meta-analysis (PubMed)

Association between race/skin color and premature birth: a systematic review with meta-analysis To analyze the association between race/skin color and the occurrence of prematurity.Meta-analysis with observational studies, selected by a systematic review in the bibliographic databases Medline and Biblioteca Virtual da Saúde with the descriptors: "Race or ethnic group" and "ethnicity and health" associated with the words "infant premature" and "obstetric labor premature". Articles published (...) to analyze possible publication biases and the quality of the studies.Of the 926 articles identified, 17 were eligible for the study. Of the 17 full texts published, seven were retrospective cohort studies, nine were cross-sectional studies, and one was a case-control study. Except for one study, the others reported a positive association between race/color of skin and prematurity. Compared with full-term newborns, the relative risk of the combined effect in those born preterm was 1.51 (95%CI 1.39-1.69

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2018 Revista de saúde pública

35. Global Epidemiology and Clinical Spectrum of Rosacea, Highlighting Skin of Color: Review and Clinical Practice Experience. (PubMed)

Global Epidemiology and Clinical Spectrum of Rosacea, Highlighting Skin of Color: Review and Clinical Practice Experience. Rosacea has been reported less frequently among individuals with skin of color than in those with white skin, but rosacea is not a rare disease in this population. In fact, rosacea might be underreported and underdiagnosed in populations with skin of color because of the difficulty of discerning erythema and telangiectasia in dark skin. The susceptibility of persons (...) with highly pigmented skin to dermatologic conditions like rosacea, whose triggers include sun exposure, is probably underestimated. Many people with skin of color who have rosacea might experience delayed diagnosis, leading to inappropriate or inadequate treatment; greater morbidity; and uncontrolled, progressive disease with disfiguring manifestations, including phymatous rosacea. In this article, we review the epidemiology of rosacea in skin of color and highlight variations in the clinical

2018 Journal of American Academy of Dermatology

36. Treating Acne in Patients With Skin of Color. (PubMed)

Treating Acne in Patients With Skin of Color. Patients with skin of color are more likely to develop acne and postinflammatory hyperpigmentation (PIH). Many therapies for acne have demonstrated efficacy in darker skin types and in the treatment of PIH. Semin Cutan Med Surg 37(supp3):S71-S73 © 2018 published by Frontline Medical Communications.2018 published by Frontline Medical Communications.

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2018 Seminars in Cutaneous Medicine and Surgery

37. Efficacy and Safety of Brodalumab in Patients with Moderate-to-Severe Plaque Psoriasis and Skin of Color: Results from the Pooled AMAGINE-2/-3 Randomized Trials. (PubMed)

Efficacy and Safety of Brodalumab in Patients with Moderate-to-Severe Plaque Psoriasis and Skin of Color: Results from the Pooled AMAGINE-2/-3 Randomized Trials. Data on treatment outcomes in patients with psoriasis who have skin of color are limited. Brodalumab has shown efficacy in patients with moderate-to-severe plaque psoriasis.Our objective was to evaluate the efficacy, safety, and health-related quality of life associated with brodalumab in patients with skin of color participating (...) in two phase III, multicenter, randomized, double-blind, placebo- and active comparator-controlled studies (AMAGINE-2/-3).Patients were self-categorized into racial subgroups (black, Asian, or white) or the non-mutually exclusive ethnic subgroup Hispanic/Latino. Patients were randomized to receive brodalumab 210 mg every 2 weeks (Q2W) or ustekinumab (45 mg in patients weighing ≤ 100 kg and 90 mg in patients weighing > 100 kg) for 52 weeks. Skin clearance was monitored using the Psoriasis Area

2018 American journal of clinical dermatology

38. Skin Cancer in Skin of Color

Skin Cancer in Skin of Color Skin Cancer in Skin of Color Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Skin Cancer in Skin of Color (...) Skin Cancer in Skin of Color Aka: Skin Cancer in Skin of Color , Skin Cancer in Black Patients , Skin Cancer in African American Patients , Skin Cancer in Asian Patients , Skin Cancer in Native American Patients , Skin Cancer in Middle Eastern Patients , Skin Cancer in Hispanic Patients From Related Chapters II. Approach: Basal cell skin cancer (BCC) Most common skin cancer in white, asian and hispanic patients (second most common Skin Cancer in Black Patients) Characteristics in Pigmented s

2018 FP Notebook

39. Skin lesion Solid Skin-colored

Skin lesion Solid Skin-colored Skin lesion Solid Skin-colored Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Skin lesion Solid Skin (...) -colored Skin lesion Solid Skin-colored Aka: Skin lesion Solid Skin-colored , Skin-Colored Papule , Skin-Colored Nodule II. Causes: Keratotic (Rough surface) Warts l wart and Calluses III. Causes: Non-Keratotic Warts s s ( s) s Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Skin lesion Solid Skin-colored." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database

2018 FP Notebook

40. Skin color parameters and Fitzpatrick phototypes in estimating the risk of skin cancer: A case-control study in the Polish population. (PubMed)

Skin color parameters and Fitzpatrick phototypes in estimating the risk of skin cancer: A case-control study in the Polish population. Light skin pigmentation is a known risk factor for skin cancer.Skin color parameters and Fitzpatrick phototypes were evaluated in terms of their usefulness in predicting the risk of skin cancer.A case-control study involved 133 individuals with skin cancer (100 with basal cell carcinoma, 21 with squamous cell carcinoma, 12 with melanoma) and 156 healthy (...) individuals. All of them had skin phototype determined and spectrophotometric skin color measurements were done on the inner surfaces of their arms and on the buttock. Using those data, prediction models were built and subjected to 17-fold stratified cross-validation.A model, based on skin phototypes, was characterized by area under the receiver operating characteristic curve = 0.576 and exhibited a lower predictive power than the models, which were mostly based on spectrophotometric variables describing

2016 Journal of American Academy of Dermatology

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