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Skin Ulcer

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15501. Leucocyte function in ulcerative colitis. Quantitative leucocyte mobilisation to skin windows and in vitro function of blood leucocytes. (PubMed)

Leucocyte function in ulcerative colitis. Quantitative leucocyte mobilisation to skin windows and in vitro function of blood leucocytes. Leucocyte function was evaluated by the in vivo mobilisation to skin windows with chambers and by the chemotactic, phagocytic, and nitro blue tetrazolium reducing capacity of blood leucocytes from 20 patients with ulcerative colitis. The total number of leucocytes mobilised to the chambers after 12 hours did not differ from those in 21 healthy volunteers (...) . After 24 and 48 hours reduced number of leucocytes were mobilised by patients with ulcerative colitis (p less than 0.01). Correspondingly, the leucocyte migration rates were normal initially but were reduced after 18 hours Mobilisation in vivo was positively correlated to the blood neutrophil count (Rho:0.5549 po less than 0.02) but unrelated to clinical activity. Blood leucocytes showed reduced random migration in vitro as well as chemotactic response to casein (p less than 0.01). Serum independent

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1982 Gut

15502. Ischemic skin lesions in ulcerative colitis (PubMed)

Ischemic skin lesions in ulcerative colitis 3978517 1985 05 16 2018 11 13 0008-4409 132 8 1985 Apr 15 Canadian Medical Association journal Can Med Assoc J Ischemic skin lesions in ulcerative colitis. 937-9 Chaun H H Day J J Dodd W A WA Dunn W L WL eng Case Reports Journal Article Canada Can Med Assoc J 0414110 0008-4409 AIM IM Adult Colitis, Ulcerative complications therapy Female Fingers Gangrene pathology Humans Ischemia etiology pathology Male Skin blood supply pathology Toes 1985 4 15 1985

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1985 Canadian Medical Association Journal

15503. Skin ulceration due to cement. (PubMed)

Skin ulceration due to cement. Despite legislation that requires manufacturers to inform the public about the dangers of contact with cement, severe ulceration from cement contact still occurs. We present a retrospective study of seven patients presenting to this department over a 2-year period. All were male and employed in the building trade, their injuries being sustained whilst at work. The injuries were to the lower limb, often multiple and required a median of seven visits before healing (...) was complete. One required hospital admission and skin grafting.

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1992 Archives of Emergency Medicine

15504. Rapid healing of venous ulcers and lack of clinical rejection with an allogeneic cultured human skin equivalent. Human Skin Equivalent Investigators Group. (PubMed)

Rapid healing of venous ulcers and lack of clinical rejection with an allogeneic cultured human skin equivalent. Human Skin Equivalent Investigators Group. To test the safety, efficacy, and immunological impact of a cultured allogeneic human skin equivalent (HSE) in the treatment of venous ulcers.Prospective, randomized study.Multicenter study in the outpatient setting.Each patient with a venous ulcer received either compression therapy alone or compression therapy and treatment with HSE (...) . The patients were evaluated for HSE safety, complete (100%) ulcer healing, time to wound closure, wound recurrence, and immune response to the HSE.The study was completed as planned in 293 randomized patients.Treatment with HSE was more effective than compression therapy in the percentage of patients healed by 6 months (63% vs 49%; P=.02, Fisher exact test, 2-tailed) and the median time to complete wound closure (61 days vs 181 days; P=.003, log-rank test). Treatment with HSE was superior to compression

1998 Archives of Dermatology

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