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Skin Ulcer

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101. Diabetic Foot Ulcers: Wound Management

Diabetic Foot Ulcers: Wound Management Diabetic Foot Ulcers: Wound Management | National Guideline Clearinghouse success fail JUL Aug 12 2017 2018 2019 02 Oct 2017 - 13 Jul 2018 COLLECTED BY Organization: Formed in 2009, the Archive Team (not to be confused with the archive.org Archive-It Team) is a rogue archivist collective dedicated to saving copies of rapidly dying or deleted websites for the sake of history and digital heritage. The group is 100% composed of volunteers and interested (...) * Remember Me Don't have an account? The AHRQ National Guideline Clearinghouse (NGC, guideline.gov) Web site will not be available after July 16, 2018 because federal funding through AHRQ will no longer be available to support the NGC as of that date. For additional information, read our . Guideline Synthesis Diabetic Foot Ulcers: Wound Management Guidelines Being Compared: International Working Group on the Diabetic Foot (IWGDF) IWGDF guidance on use of interventions to enhance the healing of chronic

2017 National Guideline Clearinghouse (partial archive)

102. Diabetic Foot Ulcers: Prevention

skin and cut toe nails straight across. ( Weak; Low ) Is footwear effective in preventing a first or recurrent non-plantar foot ulcer in an at-risk patient with diabetes? Instruct an at-risk patient with diabetes to wear properly fitting footwear to prevent a first foot ulcer, either plantar or non-plantar, or a recurrent non-plantar foot ulcer. When a foot deformity or a pre-ulcerative sign is present, consider prescribing therapeutic shoes, custom-made insoles or toe orthosis. ( Strong; Low (...) treatment, adequate footwear and education. This should be repeated or re-evaluated once every 1 to 3 months as necessary. ( Strong; Low ) Is self-management of foot health effective in preventing a first or recurrent foot ulcer in at-risk patients with diabetes? Instruct a high-risk patient with diabetes to monitor foot skin temperatures at home to prevent a first or recurrent plantar foot ulcer. This aims at identifying the early signs of inflammation, followed by action taken by the patient and care

2017 National Guideline Clearinghouse (partial archive)

103. Prevention of Plantar Ulcers in People With Diabetic Peripheral Neuropathy Using Pressure-Sensing Shoe Insoles

Practice Guidelines for the Prevention and Management of Diabetes in Canada and in regard to the formation of foot ulcers involves regular foot examination (which should include the assessment of skin temperature), prompt callus removal, and patient education. 28 In order to reduce pressure on the bottoms of the feet and accommodate foot deformities, people with diabetes should be advised to wear well-fitting or professionally fitted footwear. 25,28-31 Treatment of Diabetic Foot Ulcers Early detection (...) Prevention of Plantar Ulcers in People With Diabetic Peripheral Neuropathy Using Pressure-Sensing Shoe Insoles Prevention of Plantar Ulcers in People With Diabetic Peripheral Neuropathy Using Pressure-Sensing Shoe Insoles | CADTH.ca CADTH Document Viewer Prevention of Plantar Ulcers in People With Diabetic Peripheral Neuropathy Using Pressure-Sensing Shoe Insoles Table of Contents Search this document Prevention of Plantar Ulcers in People With Diabetic Peripheral Neuropathy Using Pressure

2017 CADTH - Issues in Emerging Health Technologies

104. VF-001 (VitroGro ECM) for venous leg ulcer

. > > > VF-001 (VitroGro ECM) for venous leg ulcer VF-001 (VitroGro ECM) for venous leg ulcer June 2017 VF-001 is a new drug that enables and accelerates chronic wound repair by providing cell attachment sites and stimulating cell activity. Consequently, skin cells are able to attach, migrate and increase rapidly to restore the wound healing process.VF-001 is applied to the wound weekly, and fits with standard care for chronic wounds. The wound closes, breaking the cycle of inflammation, and leaving (...) VF-001 (VitroGro ECM) for venous leg ulcer VF-001 (VitroGro ECM) for venous leg ulcer | Innovation Observatory toggle menu Menu Search View All Filter by Speciality Filter by Year Filter by Category This search function provides links to outputs produced by NIHR Innovation Observatory. These are briefing notes or reports on new or repurposed technologies. This search will not return all technologies currently in development as these outputs are produced as required for our stakeholders

2017 NIHR Innovation Observatory

105. Prevention of Plantar Ulcers in People With Diabetic Peripheral Neuropathy Using Pressure-Sensing Shoe Insoles

Practice Guidelines for the Prevention and Management of Diabetes in Canada and in regard to the formation of foot ulcers involves regular foot examination (which should include the assessment of skin temperature), prompt callus removal, and patient education. 28 In order to reduce pressure on the bottoms of the feet and accommodate foot deformities, people with diabetes should be advised to wear well-fitting or professionally fitted footwear. 25,28-31 Treatment of Diabetic Foot Ulcers Early detection (...) Prevention of Plantar Ulcers in People With Diabetic Peripheral Neuropathy Using Pressure-Sensing Shoe Insoles Prevention of Plantar Ulcers in People With Diabetic Peripheral Neuropathy Using Pressure-Sensing Shoe Insoles | CADTH.ca CADTH Document Viewer Prevention of Plantar Ulcers in People With Diabetic Peripheral Neuropathy Using Pressure-Sensing Shoe Insoles Table of Contents Search this document Prevention of Plantar Ulcers in People With Diabetic Peripheral Neuropathy Using Pressure

2017 CADTH - Issues in Emerging Health Technologies

106. Cytomegalovirus ulcers following radiotherapy for a Marjolin ulcer in a renal transplant recipient. (Abstract)

Cytomegalovirus ulcers following radiotherapy for a Marjolin ulcer in a renal transplant recipient. Cytomegalovirus (CMV) infection represents a major cause of morbidity and mortality in immunocompromised hosts. Skin ulceration is a rare manifestation of tissue-invasive disease, with the anogenital region being the most typical site of involvement. We present a case of CMV ulceration on the right leg occurring 16 years following renal transplantation and 1 year after adjuvant radiotherapy (...) for a Marjolin ulcer at this site. We suggest radiotherapy may provide a mechanism for local reactivation of the virus in the skin of seropositive patients.© 2018 The Australasian College of Dermatologists.

2018 Australasian Journal of Dermatology

107. From Feline Idiopathic Ulcerative Dermatitis to Feline Behavioral Ulcerative Dermatitis: Grooming Repetitive Behaviors Indicators of Poor Welfare in Cats Full Text available with Trip Pro

From Feline Idiopathic Ulcerative Dermatitis to Feline Behavioral Ulcerative Dermatitis: Grooming Repetitive Behaviors Indicators of Poor Welfare in Cats Feline idiopathic head-and-neck dermatitis-also named feline idiopathic ulcerative dermatitis (IUD)-is considered as a rare skin disease of unknown origin. It is usually associated with a crusted, non-healing, self-induced ulcer occurring most commonly on the dorsal or lateral neck or between the scapula where self-grooming by scratching (...) ). Major modifications of the cat's environment and the human-cat relationship were then recommended for IUD cats. Within 15 days after environment modifications, ulcerative lesions were healed and welfare scores improved significantly (median score of 6, significantly different from the score before environmental modifications), being similar to healthy cats (no significant differences). Only one cat was treated with a psychotropic drug, owners being reluctant to improve environmental modifications

2018 Frontiers in veterinary science

108. Infliximab, adalimumab and golimumab for treating moderately to severely active ulcerative colitis after the failure of conventional therapy

need to defaecate. Some patients may also have extra-intestinal manifestations involving joints, eyes, skin and liver. Symptoms can flare up then disappear for months or even years, but approximately 50% of patients with ulcerative colitis will relapse at least once a year. Ulcerative colitis can cause complications such as primary sclerosing cholangitis (inflamed and damaged bile ducts), bowel cancer, osteoporosis and toxic megacolon (swelling of the colon caused by trapped gases, which can (...) Infliximab, adalimumab and golimumab for treating moderately to severely active ulcerative colitis after the failure of conventional therapy Infliximab, adalimumab and golimumab Infliximab, adalimumab and golimumab for treating moder for treating moderately to se ately to sev verely activ erely active e ulcer ulcerativ ative colitis after the failure of e colitis after the failure of con conv ventional ther entional therap apy y T echnology appraisal guidance Published: 25 February 2015

2015 National Institute for Health and Clinical Excellence - Technology Appraisals

109. Vedolizumab for treating moderately to severely active ulcerative colitis

Vedolizumab for treating moderately to severely active ulcerative colitis V Vedolizumab for treating moder edolizumab for treating moderately to ately to se sev verely activ erely active ulcer e ulcerativ ative colitis e colitis T echnology appraisal guidance Published: 5 June 2015 nice.org.uk/guidance/ta342 © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility The recommendations (...) and to reduce health inequalities. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Vedolizumab for treating moderately to severely active ulcerative colitis (TA342) © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 51Contents Contents 1 Guidance 4

2015 National Institute for Health and Clinical Excellence - Technology Appraisals

110. Pressure ulcers: prevention and management

for implementation 6 Adults: risk assessment 6 Adults: skin assessment 6 All ages: care planning 6 Adults: repositioning 7 Adults: devices for prevention of pressure ulcers 7 Neonates, infants, children and young people: risk assessment 7 All ages: healthcare professional training and education 8 Adults: management of heel pressure ulcers 8 1 Recommendations 9 T erms used in this guideline 9 1.1 Prevention: adults 10 1.2 Prevention: neonates, infants, children and young people 13 1.3 Prevention: all ages 16 1.4 (...) /terms-and- conditions#notice-of-rights). Page 3 of 29This guideline replaces CG29 and CG7. This guideline is the basis of QS89. Introduction Introduction This guideline updates and replaces 'Pressure ulcers' (NICE clinical guideline 29) and 'Pressure ulcer prevention' (NICE clinical guideline 7). See About this guideline for details. Pressure ulcers are caused when an area of skin and the tissues below are damaged as a result of being placed under pressure sufficient to impair its blood supply

2014 National Institute for Health and Clinical Excellence - Clinical Guidelines

111. Superficial Bacterial Skin Infections - Guidelines for Prescribing Topical Antibiotics for impetigo and folliculitis

dermatitis: Did the patient have any recent contact with an unknown plant, chemical, or topical medicine? Lesions would be limited to exposed area Distinguished by: Sudden onset of severe pruritus Asymmetric distribution Location Allergy history : An ulcerative, deeper form of impetigo usually found on the lower leg area following a trauma to the skin such as a scratch or cut. Punched out ulcers covered with a yellow crust; raised purple margins Commonly on buttocks, thighs, legs, ankles or feet Diabetes (...) Superficial Bacterial Skin Infections - Guidelines for Prescribing Topical Antibiotics for impetigo and folliculitis Superficial Bacterial Skin Infections - Guidelines for Prescribing Topical Antibiotics for impetigo and folliculitis - medSask Home - College of Pharmacy and Nutrition - University of Saskatchewan Toggle Menu Search the U of S Search Superficial Bacterial Skin Infections - Guidelines for Prescribing Topical Antibiotics for impetigo and folliculitis The skin has an effective

2017 medSask

112. CRACKCast E137 – Skin Infections

-Clav Erythema migrans Borrelia burgdorferi Doxycycline Puncture wound through foot Pseudomomas aeruginosa Ciprofloxacin [1] List 6 risk factors for cellulitis From Uptodate: Predisposing factors for development of cellulitis and/or skin abscess include: Skin barrier disruption due to trauma (such as abrasion, penetrating wound, pressure ulcer, venous leg ulcer, insect bite, injection drug use) Skin inflammation (such as eczema, radiation therapy) Edema due to impaired lymphatic drainage Edema due (...) CRACKCast E137 – Skin Infections CRACKCast E137 - Skin Infections - CanadiEM CRACKCast E137 – Skin Infections In , , by Adam Thomas December 21, 2017 This episode of CRACKCast covers Rosen’s Chapter 129, Skin Infections. These are common and rarely life threatening, but careful consideration should be given for those who may benefit from admission over outpatient treatment. This is a big episode covering the bugs, presentations, and useful tips when treating these infections in the ED

2017 CandiEM

113. Bed rest for pressure ulcer healing in wheelchair users. Full Text available with Trip Pro

Bed rest for pressure ulcer healing in wheelchair users. Pressure ulcers, which are localised injury to the skin or underlying tissue, or both, occur when people are unable to reposition themselves to relieve pressure on bony prominences. Pressure ulcers are often difficult to heal, painful, and impact negatively on the individual's quality of life. International guidelines suggest bed rest as a component of the treatment strategy to manage pressure ulcers among wheelchair users. The potential (...) benefits and risks need to be considered when assessing the effectiveness of bed rest as an intervention for treating pressure ulcers in this population. Therefore, it was important to search and appraise existing research evidence in order to determine the impact of bed rest on the healing of pressure ulcers in wheelchair users.To assess the impact of bed rest on pressure ulcer healing, in wheelchair users, of any age, who are living or being cared for in any setting.In October 2016 we searched

2016 Cochrane

114. Reconstructive surgery for treating pressure ulcers. Full Text available with Trip Pro

Reconstructive surgery for treating pressure ulcers. The management of pressure ulcers involves several interventions ranging from pressure-relieving measures such as repositioning, to treatments that can include reconstructive surgery. Such surgery may be considered for recalcitrant wounds when full thickness skin loss arises and deeper structures such as muscle fascia and even bone are exposed. The surgery commonly involves wound debridement followed by the addition of new tissue (...) into the wound. Whilst reconstructive surgery is an accepted means of ulcer management, the benefits and harms of surgery compared with non-surgical treatments, or alternative surgical approaches are not clear.To assess the effects of reconstructive surgery for healing pressure ulcers (stage II or above), comparing surgery with no surgery or comparing alternative forms of surgery in any care setting.We searched the following electronic databases to identify reports of relevant randomised clinical trials

2016 Cochrane

115. Effect of a Basic Skin Care Product on the Structural Strength of the Skin

-epidermal separation (blistering time) is a measure of the dermo-epidermal adhesion. It has been proposed that the blistering time might be a clinically relevant parameter reflecting the mechanical integrity/stability of the dermo-epidermal junction. Clinical practice guidelines recommend the use of topical skin care products to reduce the risk for pressure ulcer and skin tear development. However, the underlying working mechanisms of most basic skin care products are poorly understood. It is known (...) Effect of a Basic Skin Care Product on the Structural Strength of the Skin Effect of a Basic Skin Care Product on the Structural Strength of the Skin - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Effect

2018 Clinical Trials

116. Assessing Tissue Remodeling in the Skin Using SFI (Skin Fluorescence Imaging)

Assessing Tissue Remodeling in the Skin Using SFI (Skin Fluorescence Imaging) Assessing Tissue Remodeling in the Skin Using SFI (Skin Fluorescence Imaging) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Assessing Tissue Remodeling in the Skin Using SFI (Skin Fluorescence Imaging) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03535077 Recruitment Status : Recruiting First Posted : May 24, 2018 Last Update Posted : May 24

2018 Clinical Trials

117. VivaScope 1500 and 3000 imaging systems for detecting skin cancer lesions

resolution (detail). Basal cell carcinoma Basal cell carcinoma 3.10 Basal cell carcinoma is the most common skin cancer. About 75 out of every 100 cases of non-melanoma skin cancers diagnosed are this type – approximately 76,000 cases in the UK in 2011. It is most likely to develop in sun-exposed areas of skin, such as the nose, forehead, cheeks, back or lower legs, and is most often diagnosed in people in middle or older age. 3.11 Basal cell carcinomas (also known as rodent ulcers) may begin as a small (...) lump and usually have shiny or pearly looking edges with a depressed center, which may become crusty or ulcerate. If untreated the ulcer can grow, becoming wider and deeper and affecting more skin tissue. Rodent ulcers can also affect other types of tissue, such as cartilage or bone. However, advanced rodent ulcers are uncommon in the UK because most people get treatment at an early stage. 3.12 There are different subtypes of basal cell skin cancers, including nodular (the most common – around 50

2015 National Institute for Health and Clinical Excellence - Diagnostics Guidance

118. Ustekinumab as Induction and Maintenance Therapy for Ulcerative Colitis. (Abstract)

Ustekinumab as Induction and Maintenance Therapy for Ulcerative Colitis. The efficacy of ustekinumab, an antagonist of the p40 subunit of interleukin-12 and interleukin-23, as induction and maintenance therapy in patients with ulcerative colitis is unknown.We evaluated ustekinumab as 8-week induction therapy and 44-week maintenance therapy in patients with moderate-to-severe ulcerative colitis. A total of 961 patients were randomly assigned to receive an intravenous induction dose (...) weeks of exposure, there were two deaths (one each from acute respiratory distress syndrome and hemorrhage from esophageal varices) and seven cases of cancer (one each of prostate, colon, renal papillary, and rectal cancer and three nonmelanoma skin cancers) among 825 patients who received ustekinumab and no deaths and one case of cancer (testicular cancer) among 319 patients who received placebo.Ustekinumab was more effective than placebo for inducing and maintaining remission in patients

2019 NEJM

119. Wound-care teams for preventing and treating pressure ulcers. Full Text available with Trip Pro

Wound-care teams for preventing and treating pressure ulcers. Pressure ulcers, which are localised injury to the skin or underlying tissue, or both, occur when people are unable to reposition themselves to relieve pressure on bony prominences. Pressure ulcers are often difficult to heal, painful and impact negatively on the individual's quality of life. The cost implications of pressure ulcer treatment are considerable, compounding the challenges in providing cost effective, efficient health (...) service delivery. International guidelines suggest that to prevent and manage pressure ulcers successfully a team approach is required. Therefore, this review has been conducted to clarify the role of wound-care teams in the prevention and management of pressure ulcers.To assess the impact of wound-care teams in preventing and treating pressure ulcers in people of any age, nursed in any healthcare setting.In April 2015 we searched: The Cochrane Wounds Group Specialised Register; The Cochrane Central

2015 Cochrane

120. Negative pressure wound therapy for treating leg ulcers. Full Text available with Trip Pro

Negative pressure wound therapy for treating leg ulcers. Leg ulcers are open skin wounds that occur between the ankle and the knee that can last weeks, months or even years and are a consequence of arterial or venous valvular insufficiency. Negative pressure wound therapy (NPWT) is a technology that is currently used widely in wound care and is promoted for use on wounds. NPWT involves the application of a wound dressing to the wound, to which a machine is attached. The machine applies (...) included one study, with 60 randomized participants, in the review. The study population had a range of ulcer types that were venous arteriolosclerotic and venous/arterial in origin. Study participants had recalcitrant ulcers that had not healed after treatment over a six-month period. Participants allocated to NPWT received continuous negative pressure until they achieved 100% granulation (wound preparation stage). A punch skin-graft transplantation was conducted and the wound then exposed to further

2015 Cochrane

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