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121. Off-Label Use of Intravenous Immunoglobulin for Dermatological Conditions: Clinical Effectiveness

. Tags dermatology, skin, skin and connective tissue diseases, skin diseases, skin manifestations, Skin, epidermal, epidermis, dermal, dermis, ivig, intravenous immunoglobulin, intravenous immunoglobulins Files Rapid Response Summary of Abstracts Published : November 3, 2017 Related Content Follow us: © 2019 Canadian Agency for Drugs and Technologies in Health Get our newsletter:

2017 Canadian Agency for Drugs and Technologies in Health - Rapid Review

123. European Society of Endocrinology Clinical Practice Guidelines on the management of adrenocortical carcinoma in adults Full Text available with Trip Pro

European Society of Endocrinology Clinical Practice Guidelines on the management of adrenocortical carcinoma in adults European Society of Endocrinology Clinical Practice Guidelines on the management of adrenocortical carcinoma in adults, in collaboration with the European Network for the Study of Adrenal Tumors in: European Journal of Endocrinology Volume 179 Issue 4 Year 2018 This site uses cookies, tags, and tracking settings to store information that help give you the very best browsing

2018 European Society of Endocrinology

124. Rare defects in Adrenal Steroidogenesis Full Text available with Trip Pro

Rare defects in Adrenal Steroidogenesis MECHANISMS IN ENDOCRINOLOGY: Rare defects in adrenal steroidogenesis in: European Journal of Endocrinology Volume 179 Issue 3 Year 2018 This site uses cookies, tags, and tracking settings to store information that help give you the very best browsing experience. If you don't change your settings, we'll assume you're happy with this. Google Translate to save searches and organize your favorite content. Not registered? Search Recently viewed (1) MECHANISMS (...) granulosa cells (and adipocytes). These tissues also express 17βHSD1 (encoded by HSD17B1 ), which converts estrone to estradiol. In genital skin (and to a lesser extent in the testis), 5α-reductase type 2 (5αRed2, encoded by SRD5A2 ) further activates testosterone to dihydrotestosterone. Figure 1 Principal pathways of steroidogenesis. The figure incorporates pathways from adrenal and gonadal steroidogenesis. StAR facilitates most cholesterol influx into steroidogenic mitochondria, but some

2018 Pediatric Endocrine Society

125. Iron, Zinc, and Vitamin D Supplementation During Breastfeeding

in populations around the world. Further study to assess the role of skin pigmentation, seasons, latitude, and sun exposure to ensure healthy vitamin D status for all populations is warranted. Currently,the25(OH)Dstatusassociatedwithtoxicityisnot de?ned. Identifying this upper limit of healthy vitamin D status is critical to future research. In addition, identifying infant vitamin D suf?ciency, the 25(OH)D status associated with optimal outcomes, is needed. Further research is also needed to determine (...) for the breastfeeding infant. The randomized controlled trials described in this protocol demonstrate that thisriskismitigatedbymaternalvitaminDsupplementation atadosethatisbothsafeforherandef?caciousfortheinfant. References 1. Shekelle PG, Woolf SH, Eccles M, et al. Clinical guide- lines: Developing guidelines. BMJ 1999;318:593–596. 2. Saarinen UM, Siimes MA, Dallman PR. Iron absorption in infants: High bioavailability of breast milk iron as in- dicated by the extrinsic tag method of iron absorption

2018 Academy of Breastfeeding Medicine

126. Fistulizing Crohn's Disease

solutions, Atlanta, Georgia, USA) to aid in the consensus process before the 2-day, face-to-face consensus meeting held in Toronto, Ontario, Canada, in September 2016. The steering committee (RP , AHS, BB, RK, JKM, and LT) and one of the nonvoting methodolo- gists (GL) developed the initial statements. Using the consen- sus web-based platform, the steering committee reviewed the results of initial literature searches and identified relevant ref - erences that were then ‘tagged’ (ie, selected and linked (...) ) to each statement. All participants then used the web-based platform and a modified Delphi process 15, 16 to vote anonymously on their level of agreement with the statements, suggest revisions, and provide comments. The statements were revised through 2 separate iterations and finalized at the consensus meeting. All participants had access to all abstracts and electronic copies of the individual tagged references. The GRADE evaluations of the evidence for each statement were provided at the meeting

2018 Canadian Association of Gastroenterology

127. Polyurethane Foam Dressings for the Prevention of Pressure Ulcers: Clinical and Cost-Effectiveness and Guidelines

of standard care. Tags wounds and injuries, pressure ulcer, polyurethane, bedsore, skin lesion, foam Files Rapid Response In Brief Rapid Response Summary with Critical Appraisal Published : April 3, 2017 Follow us: © 2019 Canadian Agency for Drugs and Technologies in Health Get our newsletter:

2017 Canadian Agency for Drugs and Technologies in Health - Rapid Review

128. Topical Antibiotics for Infection Prevention: A Review of the Clinical Effectiveness and Guidelines

the use of mupirocin in adults undergoing intensive home hemodialysis. One guideline mentioned that the use of silver sulfadiazine in preventing burn wound infection has not been proven. Tags infectious diseases, administration, topical, gramicidin, skin diseases, bacterial, skin diseases, infectious, wound infection, topical ointment, infected wound, skin ulcer Files Rapid Response Summary with Critical Appraisal Published : March 30, 2017 Related Content Follow us: © 2019 Canadian Agency for Drugs (...) Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of topical antibiotics for patients to prevent skin or wound infection? What are the evidence-based guidelines regarding the use of topical antibiotics for the prevention of skin or wound infection? Key Message Two systematic reviews and one non-randomized study showed that in non-surgical patients, exit site infection rates were statistically significantly

2017 Canadian Agency for Drugs and Technologies in Health - Rapid Review

129. The Use of Transdermal Buprenorphine Patches in Aiding in Opioid Withdrawal: Clinical Effectiveness and Guidelines

-randomized study and one evidence-based guideline were identified regarding the use of buprenorphine patches for aiding in opioid withdrawal prior to starting a patient on buprenorphine/naloxone. Tags buprenorphine, transdermal patch, medical devices, Withdrawal, addiction, addictions, Opiate, Opiates, pain management, drug addiction, Chronic pain, Opioids, Opioid, dermal, skin patches, skin patch, addicts, addict Files Rapid Response Reference List Published : June 8, 2017 Related Content Follow us: ©

2017 Canadian Agency for Drugs and Technologies in Health - Rapid Review

130. Bone-Marrow Derived Stem Cell Injections for Wound Healing and Tissue Rejuvenation: A Review of Clinical Effectiveness, Cost-Effectiveness and Guidelines

and culturing as well as measurement of relevant outcomes across studies, the authors recommended against its use in clinical practice. Tags arthroplasty, mesenchymal stem cell transplantation, mesenchymal stromal cells, orthopedics, skin ulcer, stem cells, ulcer, wound healing, cell therapy, tissue therapy, rejuvenation, adipose-derived stem cell, adipose-derived stromal cell, adipose-derived stromal cells, adipose-derived stem cells Files Rapid Response Summary with Critical Appraisal Published : May 30

2017 Canadian Agency for Drugs and Technologies in Health - Rapid Review

131. Topical Antibiotics for Infected Dermatitis: A Review of the Clinical Effectiveness and Guidelines

infected dermatitis. The long-term or routine use of topical antibiotics for infected dermatitis is not recommended. The combination of intranasal mupirocin and bleach bath may be recommended for patients with moderate to severe dermatitis who have signs of secondary bacterial infection. Tags dermatology, administration, topical, bacitracin, dermatitis, gramicidin, mupirocin, silver sulfadiazine, skin diseases, infectious, staphylococcal skin infections, Antibiotic, polymyxin, polysporin, ointment

2017 Canadian Agency for Drugs and Technologies in Health - Rapid Review

132. Oral and Dental Aspects of Child Abuse and Neglect

is suspicious for an adult human bite. 37 Bite marks found on human skin are challenging to inter- pret because of the distortion presented and the time elapsed between the injury and the analysis. 36 Recent investigations have led to questions about the scientific validity of forensic patterned evidence (bite mark analysis in particular) and its role in legal proceedings. 38 The pattern, size, contour, and color of a bite mark ideally can be evaluated by a forensic odon- tologist; a forensic pathologist (...) can be consulted if a forensic odontologist is not available. If neither specialist is available, a medical provider or dental provider experienced in identifying the patterns of child abuse injuries may examine and document the bite mark characteristics photographically with an identi- fication tag and scale marker (e.g., ruler) in the photograph. The photograph should be taken such that the angle of the camera lens is directly over the bite and in the same plane AMERICAN ACADEMY OF PEDIATRIC

2017 American Academy of Pediatric Dentistry

135. Meticillin-resistant Staphylococcus aureus (MRSA): control and management

Meticillin-resistant Staphylococcus aureus (MRSA): control and management Meticillin-resistant Staphylococcus aureus (MRSA): control and management | Great Ormond Street Hospital Google Tag Manager Navigation Search Search You are here Meticillin-resistant Staphylococcus aureus (MRSA): control and management Meticillin-resistant Staphylococcus aureus (MRSA): control and management ) clearly indicate that infection control measures do have an impact on controlling the spread of MRSA (...) or within the first 24 hours of admission and then at least every 30 days during admission (except in areas with local policy for more frequent screening e.g. NICU and PICU). Patients already known to be colonised with MRSA should have a full MRSA screen (nose, throat, hairline, axillae, groin/perineum, any skin lesions and sites of indwelling devices) taken on admission. The swabs need to be sent to the microbiology laboratory to be tested for MRSA ( ). The reasons for taking MRSA swabs must

2016 Publication 1593

136. Topotecan, pegylated liposomal doxorubicin hydrochloride, paclitaxel, trabectedin and gemcitabine for treating recurrent ovarian cancer

, vomiting, nausea, elevation of liver transaminases and alkaline phosphatase, allergic skin rash, alopecia, haematuria, mild proteinuria, influenza-like symptoms and oedema/peripheral oedema. 2.3 Gemcitabine is available in 200-mg, 1-gram and 1.5-gram vials at net prices of £29.80, £154.82 and £213.93 respectively (excluding VAT; 'British national formulary' [BNF] October 2015). The cost of gemcitabine 1000 mg/m 2 for 1 cycle (based on a body surface area of 1.7 m 2 ) on day 1 and 8 of every 21 days

2016 National Institute for Health and Clinical Excellence - Technology Appraisals

137. Diagnosis, staging and treatment of patients with Lung Cancer

the National Cancer Registry Ireland (NCRI) and population projections from the Central Statistics Office (CSO) have been combined by the NCRI to estimate the number of new cancer cases expected in five year bands from 2015 to 2040. The total number of new invasive cancer cases (including non-melanoma skin cancer) is projected to increase by 84% for females and 107% for males between 2010 and 2040, based only on changes in population size and age distribution (demography). If trends in incidence since 1994

2017 Health Service Executive (Ireland) - Clinical Guidelines

138. Diagnosis, staging and treatment of patients with lung cancer

the National Cancer Registry Ireland (NCRI) and population projections from the Central Statistics Office (CSO) have been combined by the NCRI to estimate the number of new cancer cases expected in five year bands from 2015 to 2040. The total number of new invasive cancer cases (including non-melanoma skin cancer) is projected to increase by 84% for females and 107% for males between 2010 and 2040, based only on changes in population size and age distribution (demography). If trends in incidence since 1994

2017 National Clinical Guidelines (Ireland)

139. Management of Anal Fissures

as a longitudinal tear. fissures of a longer duration will manifest one or more stigmata of chronicity, including a hypertrophied anal papilla at the proximal aspect of the fissure, a sentinel tag at the distal aspect of the fissure, and exposed internal anal sphincter muscle within the base of the fissure. METHODOLOGY t hese guidelines were built on the last set of the a merican society of Colon and Rectal surgeons practice parameters for treatment of fissure-in-ano published in 2004. a n orga- nized search (...) flap with botuli- num toxin injection has shown rapid symptom relief with healing rates ranging from 86.7% to 92% at follow-up in- tervals up to 24 months, with negligible fecal incontinence rates. 74,75 t heodoropoulos et al 76 compared the results of 30 consecutive patients who underwent lis plus V-Y peri- anal skin flap and 32 patients who previously underwent lis alone. s ignificantly less postoperative pain, faster heal- ing, and fewer soiling episodes were observed in the lis plus flap group

2017 American Society of Colon and Rectal Surgeons

140. ECCO-ESCP Surgical Crohn?s guidelines Full Text available with Trip Pro

ulcerations, mucosal tags, mucogingivitis, glossitis, and palatal ulcerations are all typical presentations. The main differential diagnosis is orofacial granulomatosis, where the lesions may be found in the absence of gastrointestinal disease. Patients with oral manifestations of CD tend to be male, present at a younger age [paediatric onset], have upper GI involvement, and perianal involvement. Gastroenterologist and colorectal surgeons working in an IBD multidisciplinary team need to be familiar

2017 Palliative Care Evidence Review Service (PaCERS)

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