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61. Management of Skin Abscesses

Management of Skin Abscesses Rotation Prep | NEJM Resident 360 Social Login Email Login Log in via Email Create Your Account We will not share your email with anyone. Password must be at least 8 characters. Show or Hide the password you are typing. Request to Join has invited you to join this group Your browser does not support video tags Welcome! NEJM Resident 360 helps you prepare for your next rotation quickly and efficiently, provides support for coping with the pressures of resident life

2014 Now@NEJM

62. Microfluidic Isolation of CD34-Positive Skin Cells Enables Regeneration of Hair and Sebaceous Glands In Vivo Full Text available with Trip Pro

technique of fluorescence-activated cell sorting (FACS). This paper describes an alternative separation method using microfluidic devices coated with degradable antibody-functionalized hydrogels. The microfluidic method allows direct injection of tissue digestate (no preprocessing tagging of cells is needed), is fast (45 minutes from injected sample to purified cells), and scalable. This method is used in this study to isolate CD34-positive (CD34+) cells from murine skin tissue digestate (...) Microfluidic Isolation of CD34-Positive Skin Cells Enables Regeneration of Hair and Sebaceous Glands In Vivo Skin stem cells resident in the bulge area of hair follicles and at the basal layer of the epidermis are multipotent and able to self-renew when transplanted into full-thickness defects in nude mice. Based on cell surface markers such as CD34 and the α6-integrin, skin stem cells can be extracted from tissue-derived cell suspensions for engraftment using the gold standard cell separation

2014 Stem cells translational medicine

63. Painful Bullous Skin Lesions

Painful Bullous Skin Lesions Rotation Prep | NEJM Resident 360 Social Login Email Login Log in via Email Create Your Account We will not share your email with anyone. Password must be at least 8 characters. Show or Hide the password you are typing. Request to Join has invited you to join this group Your browser does not support video tags Welcome! NEJM Resident 360 helps you prepare for your next rotation quickly and efficiently, provides support for coping with the pressures of resident life

2013 Now@NEJM

64. Skin Deep

Skin Deep Rotation Prep | NEJM Resident 360 Social Login Email Login Log in via Email Create Your Account We will not share your email with anyone. Password must be at least 8 characters. Show or Hide the password you are typing. Request to Join has invited you to join this group Your browser does not support video tags Welcome! NEJM Resident 360 helps you prepare for your next rotation quickly and efficiently, provides support for coping with the pressures of resident life, and equips you

2012 Now@NEJM

65. MKSAP: 32-year-old woman with a history of nonmelanoma skin cancer

MKSAP: 32-year-old woman with a history of nonmelanoma skin cancer MKSAP: 32-year-old woman with a history of nonmelanoma skin cancer MKSAP: 32-year-old woman with a history of nonmelanoma skin cancer | | December 10, 2016 9 Shares Test your medicine knowledge with the , in partnership with the . A 32-year-old woman is evaluated at a well-patient visit. Both her parents have a history of nonmelanoma skin cancer within the past year, and she is seeking counseling regarding skin cancer prevention (...) . She has a history of remote sunburns and had previously tanned as a teenager. She requests advice on how to approach sun protection to limit both future skin cancer risk as well as to prevent wrinkles and cosmetic photodamage. The patient has no other significant medical history and takes no medications. On physical examination, vital signs are normal. She has mild scattered wrinkling, scattered solar lentigines, and an average number of benign-appearing nevi. Which of the following is the most

2016 KevinMD blog

66. MKSAP: 53-year-old woman with a skin lesion

MKSAP: 53-year-old woman with a skin lesion Mohs micrographic surgery for basal cell carcinoma MKSAP: 53-year-old woman with a skin lesion | | March 5, 2016 4 Shares Test your medicine knowledge with the , in partnership with the . A 53-year-old woman is evaluated for a slowly enlarging, telangiectatic, pearly, ulcerated 1-cm plaque on the left temple. It bleeds periodically when traumatized. Medical history is significant for atrial fibrillation. She takes warfarin daily. She is otherwise (...) is a reasonable choice for BCCs in patients who are either not surgical candidates or who refuse surgery. It carries the risk of chronic radiation skin changes in subsequent years, and given the patient’s age, this makes it a less desirable option. Radiation therapy is also less cost-effective and less convenient for the patient, since it requires multiple treatments over the course of several weeks. Topical imiquimod treatment is often used for superficial BCCs and sometimes used off-label for nodular BCCs

2016 KevinMD blog

67. Image of the Week: Under the Skin

Image of the Week: Under the Skin Image of the Week: Under the Skin | Wellcome Trust Blog Life from a Wellcome Trust perspective Image of the Week: Under the Skin 19 Feb, 2016 tags: , , , , by Credit: Ben Gilbert, Wellcome Images This week, , an academic and Chemist who trains Pharmacy students at the University of East Anglia, tells us about how her skin condition can both be a valuable educational tool and a work of art. Dermatographia (or to use its full term Dermatographia urticaria (...) ) is a type of rash where the skin become raised, red and itchy after being scratched. The term dermatographia actually means “skin writing” as sufferers are able to literally write on their own skin by scratching and waiting for the allergic reaction to reveal the scribbles. This type of urticaria is quite common and in most cases the red whelts, which are caused by release of histamine, subside after about half an hour. The reaction can be prevented by taking classical anti-histamines used for allergies

2016 Wellcome Trust Blog

68. This oncologist says the USPSTF gets it wrong on skin cancer screening

This oncologist says the USPSTF gets it wrong on skin cancer screening This oncologist says the USPSTF gets it wrong on skin cancer screening This oncologist says the USPSTF gets it wrong on skin cancer screening | | August 9, 2016 124 Shares In July 2016, the U.S. Preventative Services Task Force (USPSTF) published updated skin cancer screening guidelines in JAMA, concluding “current evidence is insufficient” to screen for skin cancer in adults. The guidelines were formulated on a literature (...) review of studies conducted in asymptomatic patients 15 years and older at general risk for skin cancer from 1995-2015; after identifying nearly 13,000 articles spanning two decades of work worldwide, the authors selected 13 studies to answer specified “key questions,” such as whether direct evidence exists that skin cancer screening reduces morbidity and mortality. One study, the SCREEN trial conducted in Northern Germany, was a population-based skin cancer screening program that included physician

2016 KevinMD blog

69. The absurdly effective skin cancer PSA that will make you think twice about tanning

The absurdly effective skin cancer PSA that will make you think twice about tanning The absurdly effective skin cancer PSA that will make you think twice about tanning The absurdly effective skin cancer PSA that will make you think twice about tanning | | September 8, 2015 2K Shares educates with another epic Taylor Swift parody video. Share to promote skin cancer prevention and sun protection! … … 2K Shares Tagged as: , Subscribe to KevinMD and never miss a story! Get free updates delivered (...) free to your inbox. Subscribe Hire KevinMD to keynote your next event "Kevin's keynote presentation was perfect. Extremely rich in content, and a delivery that is world class." Related Posts More in Video < Previous post Next post > Find jobs at Careers by KevinMD.com Search thousands of physician, PA, NP, and CRNA jobs now. × The absurdly effective skin cancer PSA that will make you think twice about tanning 1 comments Comments are moderated before they are published. Please read the . Leave

2015 KevinMD blog

70. Evaluation of distal symmetric polyneuropathy: role of autonomic testing, nerve biopsy, and skin biopsy

Evaluation of distal symmetric polyneuropathy: role of autonomic testing, nerve biopsy, and skin biopsy Practice Parameter: Evaluation of distal symmetric polyneuropathy: Role of autonomic testing, nerve biopsy, and skin biopsy (an evidence-based review) | Neurology Advertisement Search for this keyword Main menu User menu Search Search for this keyword The most widely read and highly cited peer-reviewed neurology journal Share January 13, 2009 ; 72 (2) Special Article Practice Parameter (...) : Evaluation of distal symmetric polyneuropathy: Role of autonomic testing, nerve biopsy, and skin biopsy (an evidence-based review) Report of the American Academy of Neurology, American Association of Neuromuscular and Electrodiagnostic Medicine, and American Academy of Physical Medicine and Rehabilitation J. D. England , G. S. Gronseth , G. Franklin , G. T. Carter , L. J. Kinsella , J. A. Cohen , A. K. Asbury , K. Szigeti , J. R. Lupski , N. Latov , R. A. Lewis , P. A. Low , M. A. Fisher , D. N. Herrmann

2009 American Academy of Neurology

71. Thyroid hormones treatment for subclinical hypothyroidism Full Text available with Trip Pro

for the diagnosis of SCH and regional variation between populations. It is more common in women, in older people, and those of white ethnicity. What are the symptoms? Around 1 in 3 patients with SCH have no symptoms at all. The type of symptoms people link to SCH include those of overt hypothyroidism: fatigue, muscle cramps, cold sensitivity, dry skin, voice changes, and constipation. Other symptoms include poor memory, slowed thinking, weak muscles, puffy eyes, anxiety, and depression. Many of these symptoms (...) making research , L Lytvyn patient partnership expert, methodologist , A F Heen general internist , M Feller general practitioner , E Moutzouri doctor in general internal medicine et al Bekkering G E , Agoritsas T , Lytvyn L , Heen A F , Feller M , Moutzouri E et al. Thyroid hormones treatment for subclinical hypothyroidism: a clinical practice guideline BMJ 2019; 365 :l2006 BibTeX (win & mac) EndNote (tagged) EndNote 8 (xml) RefWorks Tagged (win & mac) RIS (win only) Medlars Help If you are unable

2019 BMJ Rapid Recommendations

72. Covid-19: a remote assessment in primary care Full Text available with Trip Pro

that anosmia (loss of sense of smell) is a common and early symptom. Red flags Red flag symptoms which indicate that the patient needs urgent assessment (either in person or by a good video link, depending on the clinical circumstances) include severe breathlessness or difficulty breathing, pain or pressure in the chest, blue lips or face, and a story suggestive of shock (such as cold and clammy with mottled skin, new confusion, becoming difficult to rouse, or significantly reduced urine output (...) ). Haemoptysis occurs in about 1% of covid-19 patients and seems to be a poor prognostic symptom. Remote physical examination A physical examination will be almost impossible by phone and difficult by video, so you will have to make compromises. In a video consultation, assess the patient’s demeanour, whether they are lying in bed or up and about, skin features (such as flushing, pallor, cyanosis—though note that if lighting is suboptimal this can be difficult to assess), and oropharynx. Congestion

2020 Covid-19 Ad hoc papers

73. COVID-19: infection prevention and control

and control measures necessary to reduce the risk of transmission of infectious agents from both recognised and unrecognised sources. Sources include blood and other body fluids, secretions and excretions (excluding sweat), non-intact skin or mucous membranes, and any equipment or items in the care environment. SICPs should be used by all staff, in all care settings, at all times, for all patients. 4.2 Transmission Based Precautions (TBPs) definition Transmission based precautions (TBPs) are applied when (...) procedures are required; linen is categorised as ‘used’ or ‘infectious’. All linen used in the direct care of patients with suspected and confirmed COVID-19 should be managed as COVID-19: Guidance for infection prevention and control in healthcare settings. Version 1.1, 27/03/20 Page 20 of 52 ‘infectious’ linen. Linen must be handled, transported and processed in a manner that prevents exposure to the skin and mucous membranes of staff, contamination of their clothing and the environment: Disposable

2020 Public Health England

74. Acute pancreatitis

of hypovolaemia (including decreased skin turgor, dry mucous membranes, hypotension, and sweating) are common. In more severe cases, the patient may be tachycardic and/or tachypnoeic. Elevated serum lipase or amylase concentration supports, but is not pathognomonic for, the diagnosis of acute pancreatitis. Initial treatment includes resuscitation with intravenous fluids and correction of electrolyte abnormalities, analgesia, and tight glucose control. Treatment of severe acute pancreatitis includes support (...) that they have no competing interests. Peer reviewers Assistant Professor of Medicine Attending Physician and Director of Research Columbia University Medical Center New York NY Disclosures TAG declares that he has no competing interests. Harvard Medical Faculty Physician Division of Gastroenterology Beth Israel Deaconess Medical Center Boston MA Disclosures AM declares that he has no competing interests. Consultant Hepatobiliary & Pancreatic Surgeon Department of Surgery North Manchester General Hospital

2019 BMJ Best Practice

75. Atraumatic (pencil-point) versus conventional needles for lumbar puncture Full Text available with Trip Pro

contaminated with red blood cells negatively affecting fluid analysis). Accordingly, this outcome was considered to have limited importance in the recommendation. The panel felt confident that atraumatic needles would be acceptable to patients, although this was not measured in the systematic review. Most clinicians found atraumatic and conventional needles similar to use. Some clinicians expressed potential concern regarding puncturing of the skin with the blunter atraumatic needle; however, this can (...) be overcome by inserting the lumbar puncture needle through the same skin hole used for local anaesthesia, by using an introducer needle, or by spinning the atraumatic needle around its axis while advancing the needle. Practical issues and other considerations Atraumatic needles do not eliminate the risk of complications entirely, and clinicians should continue to discuss potential adverse consequences of the lumbar puncture with their patients. Costs and resources The panel reviewed three published cost

2018 BMJ Rapid Recommendations

76. Radiofrequency treatment for haemorrhoids

patients. Rectal tenesmus was reported in 4% (1/28) of patients who had radiofrequency treatment and 19% (6/32) of patients who had rubber band ligation (p<0.05) in the RCT of 60 patients. 5.5 Skin tag formation at 12-month follow-up was reported in 7 patients who had external haemorrhoids, in the case series of 50 patients. 5.6 In addition to safety outcomes reported in the literature, specialist advisers are asked about anecdotal adverse events (events which they have heard about) and about

2017 National Institute for Health and Clinical Excellence - Interventional Procedures

78. Diabetic Foot Infections

diabetic foot infection is summarized in Figure 1. History should focus on acuity and severity of the infection and physical exam should assess the skin, vascular, neurological and musculoskeletal systems. [I-C] Grading of severity can be done using the Infectious Diseases Society of America classification scheme (Table 1). [I-C] Ankle Brachial Index and Toe Brachial Index (ABI/TBI) measurements should be taken to evaluate for underlying peripheral vascular disease. Perform an initial x-ray to evaluate (...) , or if additional imaging is needed to evaluate the extent of osteomyelitis, perform an MRI as the next imaging test. [I-C] Obtain a triple-phase bone scan in combination with a tagged WBC scan if MRI cannot be obtained but further evaluation of osteomyelitis is needed. [I-C] Treatment. Delay antibiotic initiation until after soft tissue cultures are obtained in patients with mild and moderate wound infections and without evidence of active cellulitis (Table 1). [II-E] Consult the appropriate surgical service

2020 University of Michigan Health System

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