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61. Skin, Benign Skin Lesions

, or unclear. The last 2 categories should be biopsied. Once the benign nature of the lesions is assumed, the diagnosis must be made accurately in order to assess any future malignant potential. A critical caveat is that all benign lesions must be watched by the patient and examined by a clinician should any changes occur. See the images below of benign skin lesions. Papular benign skin lesion: Acrochordon (skin tag). Papular benign skin lesion: Pyogenic granuloma. Papular lesions: Keloids developed from (...) : Papules and Plaques Acrochordon Acrochordons are extremely common lesions found in middle-aged and older persons. They are frequently found on the cervical region, axilla, upper trunk, and eyelids. Skin tags are of low clinical significance except for the questions and concerns they can generate for the patient. Synonyms for acrochordon are skin tag or fibroepithelial polyp. [ , ] (An acrochordon is shown in the image below.) Papular benign skin lesion: Acrochordon (skin tag). Acrochordons can

2014 eMedicine Surgery

62. Skin Tags

Skin Tags Skin Tags - Dermatologic Disorders - MSD Manual Professional Edition Brought to you by The trusted provider of medical information since 1899 SEARCH SEARCH MEDICAL TOPICS Common Health Topics Resources QUIZZES & CASES Quizzes Cases The trusted provider of medical information since 1899 SEARCH SEARCH MEDICAL TOPICS Common Health Topics Resources QUIZZES & CASES Quizzes Cases / / / / IN THIS TOPIC OTHER TOPICS IN THIS CHAPTER Test your knowledge Diagnostic Tests for Skin Disorders Which (...) : This is the Professional Version. CONSUMERS: Topic Resources Skin tags are common, soft, small, flesh-colored or hyperpigmented, pedunculated lesions; there are usually multiple lesions, typically on the neck, axilla, and groin. Skin Tags © Springer Science+Business Media Skin tags are usually asymptomatic but may be irritating. Treatment Removal if irritating or unsightly Irritating or unsightly skin tags can be removed by freezing with liquid nitrogen, light electrodesiccation, or excision with a scalpel or scissors

2013 Merck Manual (19th Edition)

63. Teledermatology for Diagnosis and Management of Skin Conditions

Teledermatology for Diagnosis and Management of Skin Conditions Evidence-based Synthesis Program Department of Veterans Affairs Health Services Research & Development Service Evidence-based Synthesis Program Teledermatology for Diagnosis and Management of Skin Conditions: A Systematic Review of the Evidence Department of Veterans Affairs Health Services Research & Development Service January 2010 Prepared for: Department of Veterans Affairs Veterans Health Administration Health Services (...) Research & Development Service Washington, DC 20420 Prepared by: VA Evidence Synthesis Program Center for Chronic Disease Outcomes Research Minneapolis VA Medical Center Minneapolis, MN Principal Investigator: Erin Warshaw, MD, MS Research Associates Nancy Greer, PhD Yonatan Hillman, BA Emily Hagel, MS Roderick MacDonald, MS Indulis Rutks, BS ESP Program Director Timothy J. Wilt, MD, MPHii Teledermatology for Diagnosis and Management of Skin Conditions: A Systematic Review of the Evidence Evidence

2010 Veterans Affairs Evidence-based Synthesis Program Reports

64. Questioning the link between citrus fruit and skin cancer

Questioning the link between citrus fruit and skin cancer Questioning the link between citrus fruit and skin cancer | Public Health PLOS Blogs Staff Blogs Blogs by Topic Biology & Life Sciences Earth & Environmental Sciences Multi-disciplinary Sciences Medicine & Health Research Analysis & Scientific Policy Diverse perspectives on science and medicine Staff Blogs Blogs by Topic Biology & Life Sciences Earth & Environmental Sciences Multi-disciplinary Sciences Medicine & Health Research Analysis (...) in , which are a group of naturally occurring chemical compounds called . Furanocoumarins are the compounds that cause (this is why grapefruit is not served in hospitals). Furanocoumarins increase skin photosensitivity when applied topically to the skin and also when taken orally. For example, they are used in combination with UVA light to treat psoriasis. Psoralens also used to be used in tanning creams to enhance tanning. So, although the idea may not be readily apparent to many, the authors

2015 PLOS Blogs Network

65. Painful Bullous Skin Lesions

Painful Bullous Skin Lesions Rotation Prep | NEJM Resident 360 Social Login Email Login Log in via Email Create Your Account We will not share your email with anyone. Password must be at least 8 characters. Show or Hide the password you are typing. Request to Join has invited you to join this group Your browser does not support video tags Welcome! NEJM Resident 360 helps you prepare for your next rotation quickly and efficiently, provides support for coping with the pressures of resident life

2013 Now@NEJM

66. Skin Deep

Skin Deep Rotation Prep | NEJM Resident 360 Social Login Email Login Log in via Email Create Your Account We will not share your email with anyone. Password must be at least 8 characters. Show or Hide the password you are typing. Request to Join has invited you to join this group Your browser does not support video tags Welcome! NEJM Resident 360 helps you prepare for your next rotation quickly and efficiently, provides support for coping with the pressures of resident life, and equips you

2012 Now@NEJM

67. Fluorescently Tagged pUL47 of Marek's Disease Virus Reveals Differential Tissue Expression of the Tegument Protein In Vivo (PubMed)

Fluorescently Tagged pUL47 of Marek's Disease Virus Reveals Differential Tissue Expression of the Tegument Protein In Vivo Marek's disease virus (MDV), a lymphotropic alphaherpesvirus, causes Marek's disease (MD) in chickens. MD is characterized by neurological signs, chronic wasting, and T cell lymphomas that predominate in the visceral organs. MDV replicates in a highly cell-associated manner in vitro and in vivo, with infectious virus particles being released only from feather follicle (...) epithelial (FFE) cells in the skin. Virus produced and shed from FFE cells allows transmission of MDV from infected to naïve chickens, but the mechanisms or roles of differential virus gene expression have remained elusive. Here, we generated recombinant MDV in which we fused enhanced green fluorescent protein (EGFP) to the C terminus of the tegument protein pUL47 (vUL47-EGFP) or pUL49 (vUL49-EGFP). While vUL49-EGFP was highly attenuated in vitro and in vivo, vUL47-EGFP showed unaltered pathogenic

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2012 Journal of virology

68. Tagged Red Blood Cell Scan

Tagged Red Blood Cell Scan Tagged Red Blood Cell Scan Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Tagged Red Blood Cell Scan (...) Tagged Red Blood Cell Scan Aka: Tagged Red Blood Cell Scan , Tagged Red Cell Scan , Radionuclide Red Cell Scan II. Indications Acute without obvious source based on Most useful in slower (<0.4 ml/minute) Often used to preselect patients with non-brisk for angiography III. Description Radionuclide scan with Technetium 99m-labeled red cells Labeled s circulate for 48 hours (allows for repeat scanning) Identifies sites of ing via gamma camera scan Detects bleeding down to rates as low as 0.1 ml/min IV

2015 FP Notebook

69. The absurdly effective skin cancer PSA that will make you think twice about tanning

The absurdly effective skin cancer PSA that will make you think twice about tanning The absurdly effective skin cancer PSA that will make you think twice about tanning The absurdly effective skin cancer PSA that will make you think twice about tanning | | September 8, 2015 2K Shares educates with another epic Taylor Swift parody video. Share to promote skin cancer prevention and sun protection! … … 2K Shares Tagged as: , Subscribe to KevinMD and never miss a story! Get free updates delivered (...) free to your inbox. Subscribe Hire KevinMD to keynote your next event "Kevin's keynote presentation was perfect. Extremely rich in content, and a delivery that is world class." Related Posts More in Video < Previous post Next post > Find jobs at Careers by KevinMD.com Search thousands of physician, PA, NP, and CRNA jobs now. × The absurdly effective skin cancer PSA that will make you think twice about tanning 1 comments Comments are moderated before they are published. Please read the . Leave

2015 KevinMD blog

70. A microfibril assembly assay identifies different mechanisms of dominance underlying Marfan syndrome, stiff skin syndrome and acromelic dysplasias (PubMed)

of syndromes known collectively as the acromelic dysplasias, which typically result in short stature, skin thickening and joint stiffness, have been linked to FBN1 mutations that affect specific domains of the fibrillin-1 protein. Despite their apparent phenotypic differences, dysregulation of transforming growth factor β (TGFβ) is a common factor in all of these disorders. Using a newly developed assay to track the secretion and incorporation of full-length, GFP-tagged fibrillin-1 into the extracellular (...) A microfibril assembly assay identifies different mechanisms of dominance underlying Marfan syndrome, stiff skin syndrome and acromelic dysplasias Fibrillin-1 is the major component of the 10-12 nm diameter extracellular matrix microfibrils. The majority of mutations affecting the human fibrillin-1 gene, FBN1, result in Marfan syndrome (MFS), a common connective tissue disorder characterised by tall stature, ocular and cardiovascular defects. Recently, stiff skin syndrome (SSS) and a group

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2015 Human molecular genetics

71. Microfluidic Isolation of CD34-Positive Skin Cells Enables Regeneration of Hair and Sebaceous Glands In Vivo (PubMed)

technique of fluorescence-activated cell sorting (FACS). This paper describes an alternative separation method using microfluidic devices coated with degradable antibody-functionalized hydrogels. The microfluidic method allows direct injection of tissue digestate (no preprocessing tagging of cells is needed), is fast (45 minutes from injected sample to purified cells), and scalable. This method is used in this study to isolate CD34-positive (CD34+) cells from murine skin tissue digestate (...) Microfluidic Isolation of CD34-Positive Skin Cells Enables Regeneration of Hair and Sebaceous Glands In Vivo Skin stem cells resident in the bulge area of hair follicles and at the basal layer of the epidermis are multipotent and able to self-renew when transplanted into full-thickness defects in nude mice. Based on cell surface markers such as CD34 and the α6-integrin, skin stem cells can be extracted from tissue-derived cell suspensions for engraftment using the gold standard cell separation

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2014 Stem cells translational medicine

72. THE USE OF RADIOACTIVE CHROMIUM 51 AS AN ERYTHROCYTE TAGGING AGENT FOR THE DETERMINATION OF RED CELL SURVIVAL IN VIVO (PubMed)

THE USE OF RADIOACTIVE CHROMIUM 51 AS AN ERYTHROCYTE TAGGING AGENT FOR THE DETERMINATION OF RED CELL SURVIVAL IN VIVO 13108994 2003 05 01 2018 12 01 0021-9738 32 12 1953 Dec The Journal of clinical investigation J. Clin. Invest. The use of radioactive chromium 51 as an erythrocyte tagging agent for the determination or red cell survival in vivo. 1260-76 EBAUGH F G FG Jr EMERSON C P CP ROSS J F JF eng Journal Article United States J Clin Invest 7802877 0021-9738 0 Chromium Radioisotopes (...) 0R0008Q3JB Chromium OM Cell Survival Chromium Chromium Radioisotopes Erythrocytes Humans Skin Neoplasms 5425:30152:110:166 CHROMIUM/radioactive ERYTHROCYTES 1953 12 1 1953 12 1 0 1 1953 12 1 0 0 ppublish 13108994 10.1172/JCI102855 PMC438472 J Clin Invest. 1950 Dec;29(12):1604-13 14794790 J Clin Invest. 1950 Dec;29(12):1614-9 14794791 J Clin Invest. 1947 Jul;26(4):739-46 16695465 J Clin Invest. 1946 Nov;25(6):838-47 16695381 J Clin Invest. 1947 Jul;26(4):687-703 16695462 J Lab Clin Med. 1952 Apr;39(4):595

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1953 Journal of Clinical Investigation

73. THE POTENTIAL LIFE SPAN AND ULTIMATE SURVIVAL OF FRESH RED BLOOD CELLS IN NORMAL HEALTHY RECIPIENTS AS STUDIED BY SIMULTANEOUS Cr51 TAGGING AND DIFFERENTIAL HEMOLYSIS (PubMed)

THE POTENTIAL LIFE SPAN AND ULTIMATE SURVIVAL OF FRESH RED BLOOD CELLS IN NORMAL HEALTHY RECIPIENTS AS STUDIED BY SIMULTANEOUS Cr51 TAGGING AND DIFFERENTIAL HEMOLYSIS 14367517 2003 05 01 2018 12 01 0021-9738 34 4 1955 Apr The Journal of clinical investigation J. Clin. Invest. The potential life span and ultimate survival of fresh red blood cells in normal healthy recipients as studied by simultaneous Cr51 tagging and differential hemolysis. 629-36 EADIE G S GS BROWN I W IW Jr eng Journal (...) Article United States J Clin Invest 7802877 0021-9738 OM Cell Death Erythrocytes Hemolysis Humans Skin Neoplasms 5528:18360:210 ERYTHROCYTES 1955 4 1 1955 4 1 0 1 1955 4 1 0 0 ppublish 14367517 10.1172/JCI103112 PMC438669 J Clin Invest. 1954 Feb;33(2):163-78 13130684 J Gen Physiol. 1953 Jan;36(3):327-43 13022930 J Clin Invest. 1954 Jun;33(6):835-43 13163175 J Lab Clin Med. 1953 Sep;42(3):358-67 13085025 Blood. 1951 Dec;6(12):1284-92 14886401 J Lab Clin Med. 1953 May;41(5):796-801 13053037 J Clin

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1955 Journal of Clinical Investigation

74. A STUDY OF ANDROGEN AND ESTROGEN RECEPTORS α, β IN SKIN TAGS (PubMed)

A STUDY OF ANDROGEN AND ESTROGEN RECEPTORS α, β IN SKIN TAGS In women, the age of 50 is suggested to be the turning point of life at which the development of skin tags comes to a stop. A major event that occurs around this period of life is menopause/andropause. After menopause, estrogen receptors amounts decrease significantly. As skin is considered as the largest nonreproductive target on which estrogens and androgens act, we assume a possible relationship between the pathogenesis of skin (...) tags and sex steroid balance. Another phenomenon is the association of skin tags in obese patients, which may also be explained by the interplay of sex steroids and their receptors in skin tags.Here we see that in obese patients, hyperandrogenism occurs as a result of hyperinsulinemia as well as peripheral conversion of estrogens into androgens in the excessive adipose tissue. To examine the possible role of androgen and estrogen receptors in etiopathogenesis of skin tags.To examine

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2010 Indian journal of dermatology

75. Evaluation of distal symmetric polyneuropathy: role of autonomic testing, nerve biopsy, and skin biopsy

Evaluation of distal symmetric polyneuropathy: role of autonomic testing, nerve biopsy, and skin biopsy Practice Parameter: Evaluation of distal symmetric polyneuropathy: Role of autonomic testing, nerve biopsy, and skin biopsy (an evidence-based review) | Neurology Advertisement Search for this keyword Main menu User menu Search Search for this keyword The most widely read and highly cited peer-reviewed neurology journal Share January 13, 2009 ; 72 (2) Special Article Practice Parameter (...) : Evaluation of distal symmetric polyneuropathy: Role of autonomic testing, nerve biopsy, and skin biopsy (an evidence-based review) Report of the American Academy of Neurology, American Association of Neuromuscular and Electrodiagnostic Medicine, and American Academy of Physical Medicine and Rehabilitation J. D. England , G. S. Gronseth , G. Franklin , G. T. Carter , L. J. Kinsella , J. A. Cohen , A. K. Asbury , K. Szigeti , J. R. Lupski , N. Latov , R. A. Lewis , P. A. Low , M. A. Fisher , D. N. Herrmann

2009 American Academy of Neurology

76. Fat in the skin: Triacylglycerol metabolism in keratinocytes and its role in the development of neutral lipid storage disease (PubMed)

Fat in the skin: Triacylglycerol metabolism in keratinocytes and its role in the development of neutral lipid storage disease Keratinocyte differentiation is essential for skin development and the formation of the skin permeability barrier. This process involves an orchestrated remodeling of lipids. The cleavage of precursor lipids from lamellar bodies by β-glucocerebrosidase, sphingomyelinase, phospholipases and sterol sulfatase generates ceramides, non-esterified fatty acids and cholesterol (...) for the lipid-containing extracellular matrix, the lamellar membranes in the stratum corneum. The importance of triacylglycerol (TAG) hydrolysis for the formation of a functional permeability barrier was only recently appreciated. Mice with defects in TAG synthesis (acyl-CoA:diacylglycerol acyltransferase-2-knock-out) or TAG catabolism (comparative gene identification-58, -CGI-58-knock-out) develop severe permeability barrier defects and die soon after birth because of desiccation. In humans, mutations

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2011 Dermato-endocrinology

77. POMC and TP53 genetic variability and risk of basal cell carcinoma of skin: Interaction between host and genetic factors. (PubMed)

work is to test association between POMC and TP53 genetic variability, the possible interplay with host factors and the risk of basal cell carcinoma of skin.We covered the variability of the two genes we used 17 tagging polymorphisms in 529 BCC cases and 532 healthy controls. We have also tested the possible interactions between the genetic variants and three known risk factors for BCC: skin complexion, sun effect and skin response to sun exposure.We did not observe any statistically significant (...) POMC and TP53 genetic variability and risk of basal cell carcinoma of skin: Interaction between host and genetic factors. Basal cell carcinoma (BCC) of the skin is the most common neoplasm among the Caucasian population of the western world. Ultraviolet (UV) radiation-induced p53 activation promotes cutaneous pigmentation by increasing transcriptional activity of pro-opiomelanocortin (POMC) in the skin. Induction of POMC/α-melanocyte-stimulating hormone (α-MSH) activates the melanocortin 1

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2011 Journal of dermatological science

78. Are there any protocols/guidelines that deal with dermatology procedures or minor surgery procedures in general practice ( eg warts, sebaceous cysts, lipoma, skin tags)?

Are there any protocols/guidelines that deal with dermatology procedures or minor surgery procedures in general practice ( eg warts, sebaceous cysts, lipoma, skin tags)? Are there any protocols/guidelines that deal with dermatology procedures or minor surgery procedures in general practice ( eg warts, sebaceous cysts, lipoma, skin tags)? - Trip Database or use your Google+ account Liberating the literature ALL of these words: Title only Anywhere in the document ANY of these words: Title only (...) with dermatology procedures or minor surgery procedures in general practice ( eg warts, sebaceous cysts, lipoma, skin tags)? We searched the NLH Skin Disorders Specialist Library, the British Assocation of Dermatology and the Primary Care Dermatology Society but found no guidelines or protocols on undertaking minor dermatology procedures in primary care. However, the PatientPlus website contains two recently posted articles on minor surgery. The first article outlines the techniques of local anaesthesia

2008 TRIP Answers

79. Acute pancreatitis

of hypovolaemia (including decreased skin turgor, dry mucous membranes, hypotension, and sweating) are common. In more severe cases, the patient may be tachycardic and/or tachypnoeic. Elevated serum lipase or amylase concentration supports, but is not pathognomonic for, the diagnosis of acute pancreatitis. Initial treatment includes resuscitation with intravenous fluids and correction of electrolyte abnormalities, analgesia, and tight glucose control. Treatment of severe acute pancreatitis includes support (...) that they have no competing interests. Peer reviewers Assistant Professor of Medicine Attending Physician and Director of Research Columbia University Medical Center New York NY Disclosures TAG declares that he has no competing interests. Harvard Medical Faculty Physician Division of Gastroenterology Beth Israel Deaconess Medical Center Boston MA Disclosures AM declares that he has no competing interests. Consultant Hepatobiliary & Pancreatic Surgeon Department of Surgery North Manchester General Hospital

2019 BMJ Best Practice

80. Acute pancreatitis

of hypovolaemia (including decreased skin turgor, dry mucous membranes, hypotension, and sweating) are common. In more severe cases, the patient may be tachycardic and/or tachypnoeic. Elevated serum lipase or amylase concentration supports, but is not pathognomonic for, the diagnosis of acute pancreatitis. Initial treatment includes resuscitation with intravenous fluids and correction of electrolyte abnormalities, analgesia, and tight glucose control. Treatment of severe acute pancreatitis includes support (...) that they have no competing interests. Peer reviewers Assistant Professor of Medicine Attending Physician and Director of Research Columbia University Medical Center New York NY Disclosures TAG declares that he has no competing interests. Harvard Medical Faculty Physician Division of Gastroenterology Beth Israel Deaconess Medical Center Boston MA Disclosures AM declares that he has no competing interests. Consultant Hepatobiliary & Pancreatic Surgeon Department of Surgery North Manchester General Hospital

2018 BMJ Best Practice

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