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Skin Discoloration

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1341. A double-blind randomized clinical trial on the effectiveness of a daily glycolic acid 5% formulation in the treatment of photoaging. (Abstract)

assessments for photoaging. There was statistically significant improvement favoring the active-cream in general skin texture and discoloration. There was a trend favoring glycolic acid in reduction of wrinkles, but this did not achieve statistical significance.Unneutralized 5% glycolic acid topical cream when used on a regular daily basis can improve some photoaging effects.

1998 Dermatologic Surgery Controlled trial quality: uncertain

1342. Addison, pernicious anemia and adrenal insufficiency Full Text available with Trip Pro

insufficiency, based particularly on the discoloration of the skin in these conditions. Three major sources of possible confusion for historians who are attempting to understand Addison's views include Addison's early attempts to link pernicious anemia with disease of the suprarenal capsules, Addison's redefinition of pernicious anemia in his monograph on adrenal disease, and several confusing statements made by Wilks and Daldy in the first reprint of Addison's monograph.

1985 Canadian Medical Association Journal

1343. Pharmacologic features and effects of neuroleptics. Full Text available with Trip Pro

. These include tardive dyskinesia, skin discoloration and corneal deposits. The clinician must consider the pattern aand severity of each patient's present and past psychotic episodes before deciding whether maintenance therapy with neuroleptics is justified. If it is, doses should be re-evaluated frequently and kept as low as possible. Concomitant administration of anticholinergic agents should be avoided if possible. Most important, the long-term administration of neuroleptics should be prescribed only

1981 Canadian Medical Association Journal

1344. Benign Carotenemia in Children Full Text available with Trip Pro

Benign Carotenemia in Children The author discusses five infants, aged eight to 11 months, with carotenemia secondary to excessive consumption of carotene-containing foods. These infants had white sclerae in spite of yellow discoloration of the skin. Simple elimination of these foods led to clearing of the yellow skin color and normalization of serum carotene levels. All infants had normal vitamin A levels, white cell count, serum glucose, lipids, liver- and thyroid-function tests. The benign

1989 Canadian Family Physician

1345. Activities and functional assessment 1 year after spinal fusion for paralytic scoliosis Full Text available with Trip Pro

with the variables classified according to WHO's International Classification of Impairments, Disabilities, and Handicaps (ICIDH). This consists of the patient's/relative's motives for surgery, persistent skin discoloration, ambulating or use of wheelchair, use of a brace, sitting balance, weight distribution on a sitting surface, angle of scoliosis, reaching, pain estimation, activities of daily living (ADL) Klein and Bell, care given, time spent resting, and seating supports. The set of instrument also (...) included a follow-up questionnaire comprising 12 different areas, where the patients/relatives assessed the results of surgery. The study showed that spinal fusion in paralytic scoliosis led to showed improvements in the whole group of patients at the Impairment level in the angle of scoliosis, sitting balance, weight distribution, and reduced number of patients with persistent skin discoloration, and at the Handicap level in reduced time for resting during the day, reduced number of seating supports

1999 European Spine Journal

1346. Sample size, confidence, and contingency judgement. (Abstract)

Sample size, confidence, and contingency judgement. According to statistical models, the acquisition function of contingency judgement is due to confidence increasing with sample size. According to associative models, the function reflects the accumulation of associative strength on which the judgement is based. Which view is right? Thirty university students assessed the relation between a fictitious medication and a symptom of skin discoloration in conditions that varied sample size (4, 6, 8

2002 Canadian journal of experimental psychology = Revue canadienne de psychologie expérimentale

1347. Effect of diaspirin crosslinked hemoglobin (DCLHb HemAssist) during high blood loss surgery on selected indices of organ function. (Abstract)

. There were no occurrences of cardiac ischemia. myocardial infarction, stroke, or pulmonary edema, by clinical or laboratory parameters up to the 28th postoperative day (POD). Seven of 12 (58%) DCLHb patients had yellow skin discoloration vs. none in the PRBC group (P < 0.01). Two of four non-urologic surgery patients developed asymptomatic postoperative hemoglobinuria after DCLHb. Creatinine clearance was unchanged postoperatively. Because of hemoglobin interference, bilirubin, gamma-glutamyl transferase (...) blood cell count or coagulation tests.Administration of approximately 1000 mg/kg DCLHb was associated with transient arterial hypertension, gastrointestinal side effects, laboratory abnormalities, yellow skin discoloration, and hemoglobinuria. These observations point to opportunities for improvement in future synthetic hemoglobin design.

2002 Artificial cells, blood substitutes, and immobilization biotechnology Controlled trial quality: uncertain

1348. Non-ablative cutaneous remodeling with a 1.45 microm mid-infrared diode laser: phase II. (Abstract)

with Fitzpatrick skin phototypes I-III were treated. Single facial rhytids were treated on three separate occasions 3 weeks apart (six periorbital and three perioral). Single, control wrinkles on the contralateral sides were treated with cryogen spray cooling alone. Subjects were treated with single passes with a 5mm spot for the first two treatments. Owing to a modification in the handpiece design, a 4mm spot was used for the third and final treatment. The average power was 12 W. At each treatment visit (...) 2-3 days. Superficial, branny hyperpigmentation occurred in six patients at both treatment and control sides. This discoloration resolved within 1 week of treatment and left no residual pigment alterations. No whitening or residual scarring occurred. Rhytid scores improved from a baseline score of 2.3 to 1.8 at 6 months after treatment (p>0.05). Patient acceptance of the treatment was high, but most felt that there was little improvement of the treated rhytids.Although the 1.45 microm diode

2002 Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology Controlled trial quality: uncertain

1349. Postoperative discomfort associated with surgical and nonsurgical endodontic retreatment. (Abstract)

in single cases. Analgesics were significantly more often consumed after periapical surgery. Patients reported absence from work mainly due to swelling and discoloration of the skin. This was found to occur only after surgical retreatment. Conclusively, surgical retreatment resulted in more discomfort and tended to bring about greater indirect costs than nonsurgical retreatment.

2000 Endodontics & dental traumatology Controlled trial quality: uncertain

1350. Comparison of higher-dose intradermal hepatitis B vaccination to standard intramuscular vaccination of healthcare workers. (Abstract)

effect of intradermal vaccination was skin discoloration at injection sites, which persisted for at least 2 years postvaccination. Two thirds (112/166) of respondents reported that they would have selected the ID route despite the discoloration.Higher-dose ID vaccination (3 vs 1 microg per injection) uses one sixth of the dose required for standard IM vaccination. It is a cost-effective way to vaccinate populations against hepatitis B virus, but the long-term efficacy of the ID route must still

2000 Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America Controlled trial quality: uncertain

1351. The effects of hydrocolloid dressing and gentian violet on radiation-induced moist desquamation wound healing. (Abstract)

was not statistically different in the two groups. These findings suggest that the lower score of dressing satisfaction level in the gentian violet group may result from the skin discoloration and drying effects of the treatment, which renders patients unable to move or stretch their skin. Although the aim is to have complete wound healing, this may not be realistic for many lesions such as radiotherapy-induced moist desquamation wounds. The best evidence on which to make decisions about individual care can now

2000 Cancer nursing Controlled trial quality: uncertain

1352. The use of bovine hemoglobin glutamer-250 (Hemopure) in surgical patients: results of a multicenter, randomized, single-blinded trial. (Abstract)

in the analysis. We studied clinical outcomes and compared hematologic findings, blood chemistry values, and blood use in the two treatment groups. There were no patient deaths in this study. No pattern of clinically significant laboratory abnormalities could be attributed to exposure to HBOC-201. In the HBOC-201 group, 2 patients had a transient increased concentration of serum transaminases and 6 had transient skin discoloration. One patient in the HBOC-201 group had mast cell degranulation with hypotension

2002 Anesthesia and analgesia Controlled trial quality: uncertain

1353. Argyria associated with colloidal silver supplementation. (Abstract)

Argyria associated with colloidal silver supplementation. A 65-year-old male presented for skin examination and was incidentally noted to have discoloration of the fingernails. These findings were completely asymptomatic. The patient had been taking colloidal silver supplementation (Silverzone 140 ppm silver Gifts of Nature, St. George, UT, USA) for 2 years as therapy for diabetes. He first noticed the onset of nail discoloration 1 year ago. His past medical history included type II diabetes (...) and hypertension. His current medications were metformin, glyburide, and benazepril. Physical examination revealed slate-gray discoloration involving the lunulae of the fingernails (Fig. 1). The skin, mucous membranes, and sclerae were unaffected.

2003 International Journal of Dermatology

1354. Along these lines... (Abstract)

Along these lines... Non-melanotic discoloration of the skin can result from the accumulation of various internal agents (ingestion, inhalation, or injection), chemicals or drugs, such as heavy metals, amiodarone, tetracycline, clofazimine and others, or exogenous (topical) substances. Identifying the causative agent frequently requires a thorough investigation and clever detective work, including visits to the home and workplace. It is, however, rare that the patient presents at a clinic

2003 International Journal of Dermatology

1355. Development and validation of a health-related quality of life instrument for women with melasma. (Abstract)

Evaluation scale, the Dermatology Life Quality Index (DLQI), a skin discoloration evaluation questionnaire, and a measure of perceived life quality difference without melasma. The 10-item MELASQOL scale was devised from the comprehensive HRQoL assessment battery.The psychometric properties of the MELASQOL were comparable with the properties of the DLQI and the SKINDEX-16. The MELASQOL scores were highly correlated with the other HRQoL measures. The discriminatory ability of the MELASQOL is superior (...) to the SKINDEX-16 and the DLQI for melasma. The three life domains most adversely affected by melasma (social life, recreation/leisure and emotional well-being) were highlighted by this instrument. These were the same three areas of life that patients believed would improve the most if they no longer were affected by the disease.The MELASQOL can be used to evaluate objectively the effect of melasma on a patient's HRQoL. The high correlation with the DLQI, the SKINDEX-16 and the skin discoloration

2003 British Journal of Dermatology

1356. Bullous appearance of pilomatricoma. (Abstract)

Bullous appearance of pilomatricoma. Pilomatricomas, which are usually solitary, firm to hard tumors that are covered by normal skin, rarely show a bullous appearance.To discuss, through a case report, the clinical and histopathologic characteristics of bullous pilomatricomas.A 15-year-old boy presented with a firm, well-defined tumor on his right arm that showed dark-blue discoloration and bullous formation over it.Excisional biopsy was performed, and histopathologic examination confirmed

2003 Dermatologic Surgery

1357. Intense pulsed light in the treatment of striae distensae. (Abstract)

by IPL.A prospective study was carried out in 15 women, all of them having late stage striae distensae of the abdomen. Five sessions of IPL were performed in each one, once every two weeks. Skin biopsies and before and after photographs were taken of all the patients. Data concerning skin features (number of stretch marks in a square of 5 cm per side, sum of all the stretch marks to determine the total length, discolorations and general appearance) were all assessed before each session and at the end (...) Intense pulsed light in the treatment of striae distensae. Intense Pulsed Light (IPL) is a noncoherent, nonlaser, filtered flashlamp, emitting a broadband visible light. Its efficacy has been reported recently in the treatment of photodamaged facial skin, promoting the production of neo collagen and ordering of elastic fibers. We don't know however, its efficacy in the treatment of striae distensae.To assess gross and microscopical changes that occur in the striae distensae when treated

2002 Dermatologic Surgery

1358. Successful treatment of leukaemia cutis with cladribine in a patient with B-cell chronic lymphocytic leukaemia. (Abstract)

population of B lymphocytes both in the bone marrow and in the skin. The patient received four courses of cladribine 0.12 mg kg-1 daily as a 2-h infusion for five consecutive days. The courses were repeated at monthly intervals. The lymphocytosis gradually decreased and the PB count normalized after three courses. At the same time, a significant decrease in the cutaneous symptoms was observed. The patient became free of skin tumours after the fourth course of cladribine; only slight discoloration (...) Successful treatment of leukaemia cutis with cladribine in a patient with B-cell chronic lymphocytic leukaemia. Cutaneous presentation of B-cell chronic lymphocytic leukaemia (B-CLL) is uncommon, and the influence of skin changes on B-CLL prognosis is unclear. We report a patient with B-CLL Rai II, with multiple nodular skin infiltrations on the trunk, upper arms and thighs as well as constitutional symptoms, who was successfully treated with cladribine. The peripheral blood (PB) lymphocytes

2002 British Journal of Dermatology

1359. Should you remove sea urchin spikes from the skin

Should you remove sea urchin spikes from the skin Should you remove sea urchin spikes from the skin - Trip Database or use your Google+ account Turning Research Into Practice ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing (...) , educational courses and news. For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via Should you remove sea urchin spikes from the skin This is an unusual question! We cannot be certain if the type of sea urchin alters the answer. However, we have found some general information on the topic which might be of interest. eMedicine has a chapter, ‘Echinoderm Envenomations’ [1

2006 TRIP Answers

1360. Neuroskin Forte for Dry Skin Relief in Eczema and Psoriasis

Neuroskin Forte for Dry Skin Relief in Eczema and Psoriasis Neuroskin Forte for Dry Skin Relief in Eczema and Psoriasis - Full Text View - Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Neuroskin Forte for Dry Skin Relief (...) Collaborator: AVVAA World Healthcare Products, Inc. Information provided by (Responsible Party): Rutgers, The State University of New Jersey ( University of Medicine and Dentistry of New Jersey ) Study Details Study Description Go to Brief Summary: The purpose of this study is to assess the efficacy of Neuroskin Forte in relieving the symptoms of dry skin in adults with psoriasis or eczema. Condition or disease Intervention/treatment Phase Psoriasis Eczema Drug: Neuroskin Forte Drug: Placebo Application

2005 Clinical Trials

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